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公开(公告)号:US07914900B2
公开(公告)日:2011-03-29
申请号:US12196061
申请日:2008-08-21
申请人: Sidney T. Smith , Larry Rosenbaum , Sue Rosenbaum, legal representative , Gregg Nebgen , Steven H. Giovanetto
CPC分类号: B32B27/30 , A61J1/10 , A61M2207/00 , B32B1/08 , Y10S128/24 , Y10S128/912 , Y10S206/828 , Y10S604/905 , Y10T428/1334 , Y10T428/1341 , Y10T428/2495 , Y10T428/269 , Y10T428/31757 , Y10T428/31909 , Y10T428/31913 , Y10T428/31935
摘要: The present invention provides a receptacle (30) for a therapeutic fluid susceptible to deterioration on exposure to a gas such as oxygen or carbon dioxide. The receptacle (30) has walls of sheet material each including at least one layer forming a barrier essentially impermeable to such gas, and a seal sealing the walls together in a region thereof. A transfer tube (40) is sealed in the seal having a proximal end in the receptacle (30), a distal end accessible from outside the receptacle (30), a flow passage (56) extending between said proximal and distal ends, and a closure (54) blocking flow through the flow passage (56) adapted to be pierced by a tubular needle for transfer of therapeutic through the needle. The transfer tube (40) and closure (54) are essentially impermeable to said gas.
摘要翻译: 本发明提供了一种用于治疗性液体的容器(30),其易于暴露于诸如氧气或二氧化碳的气体中的劣化。 容器(30)具有片状材料壁,每个层包括至少一层形成对这种气体基本上不可渗透的阻挡层,以及在其区域中将壁密封在一起的密封件。 传送管(40)被密封在密封件中,该密封件具有在容器(30)中的近端,可从容器(30)的外部接近的远端,在所述近端和远端之间延伸的流动通道(56) 封闭件(54)阻止流过通道(56)的流动,该流动通道(56)适于被管状针刺穿,用于通过针转运治疗剂。 输送管(40)和封闭件(54)对所述气体基本上是不可渗透的。
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公开(公告)号:US20090022985A1
公开(公告)日:2009-01-22
申请号:US12196061
申请日:2008-08-21
CPC分类号: B32B27/30 , A61J1/10 , A61M2207/00 , B32B1/08 , Y10S128/24 , Y10S128/912 , Y10S206/828 , Y10S604/905 , Y10T428/1334 , Y10T428/1341 , Y10T428/2495 , Y10T428/269 , Y10T428/31757 , Y10T428/31909 , Y10T428/31913 , Y10T428/31935
摘要: The present invention provides a receptacle (30) for a therapeutic fluid susceptible to deterioration on exposure to a gas such as oxygen or carbon dioxide. The receptacle (30) has walls of sheet material each including at least one layer forming a barrier essentially impermeable to such gas, and a seal sealing the walls together in a region thereof. A transfer tube (40) is sealed in the seal having a proximal end in the receptacle (30), a distal end accessible from outside the receptacle (30), a flow passage (56) extending between said proximal and distal ends, and a closure (54) blocking flow through the flow passage (56) adapted to be pierced by a tubular needle for transfer of therapeutic through the needle. The transfer tube (40) and closure (54) are essentially impermeable to said gas.
摘要翻译: 本发明提供了一种用于治疗性液体的容器(30),其易于暴露于诸如氧气或二氧化碳的气体中的劣化。 容器(30)具有片状材料壁,每个层包括至少一层形成对这种气体基本上不可渗透的阻挡层,以及在其区域中将壁密封在一起的密封件。 传送管(40)被密封在密封件中,该密封件具有在容器(30)中的近端,可从容器(30)的外部接近的远端,在所述近端和远端之间延伸的流动通道(56) 封闭件(54)阻止流过通道(56)的流动,该流动通道(56)适于被管状针刺穿,用于通过针转运治疗剂。 输送管(40)和封闭件(54)对所述气体基本上是不可渗透的。
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公开(公告)号:US06974447B2
公开(公告)日:2005-12-13
申请号:US10124599
申请日:2002-04-16
申请人: Sidney T. Smith , Larry Rosenbaum , Gregg Nebgen , William S. Hurst , William S. Hoerle , Adel M. Sadik , Melissa J. Skelnik , Steven H. Giovanetto , Bradley Buchanan
发明人: Sidney T. Smith , Larry Rosenbaum , Gregg Nebgen , William S. Hurst , William S. Hoerle , Adel M. Sadik , Melissa J. Skelnik , Steven H. Giovanetto , Bradley Buchanan
IPC分类号: B65D30/02 , A61J1/00 , A61J1/05 , A61J1/10 , B32B1/08 , B32B27/08 , B32B27/30 , B65D65/40 , A61B19/00 , A61M37/00 , B29D22/00 , B65D30/08 , B65D37/00
CPC分类号: B32B27/30 , A61J1/10 , A61M2207/00 , B32B1/08 , Y10S128/24 , Y10S128/912 , Y10S206/828 , Y10S604/905 , Y10T428/1334 , Y10T428/1341 , Y10T428/2495 , Y10T428/269 , Y10T428/31757 , Y10T428/31909 , Y10T428/31913 , Y10T428/31935
摘要: The present invention provides a receptacle for a therapeutic fluid susceptible to deterioration on exposure to a gas such as oxygen or carbon dioxide. The receptacle has walls of sheet material each including at least one layer forming a barrier essentially impermeable to such gas, and a seal sealing the walls together in a region thereof. A transfer tube is sealed in the seal having a proximal end in the receptacle, a distal end accessible from outside the receptacle, a flow passage extending between said proximal and distal ends, and a closure blocking flow through the flow passage adapted to be pierced by a tubular needle for transfer of therapeutic through the needle. The transfer tube and closure are essentially impermeable to said gas.
摘要翻译: 本发明提供了一种用于暴露于诸如氧气或二氧化碳等气体的劣化的治疗性流体的容器。 容器具有片状材料壁,每个层包括至少一层形成对这种气体基本上不可渗透的阻挡层,以及将壁密封在一起的区域中。 输送管被密封在密封件中,该密封件具有在容器中的近端,可从容器外部接近的远端,在所述近端和远端之间延伸的流动通道,以及封闭流经所述流动通道的流体,其适于被 用于通过针转运治疗的管状针。 转移管和封闭物基本上不透气于所述气体。
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公开(公告)号:US5693387A
公开(公告)日:1997-12-02
申请号:US484767
申请日:1995-06-07
申请人: Larry Rosenbaum , Steven Giovanetto , Sidney T. Smith , David V. Bacehowski , Gregg Nebgen , Varsha Kalyankar
发明人: Larry Rosenbaum , Steven Giovanetto , Sidney T. Smith , David V. Bacehowski , Gregg Nebgen , Varsha Kalyankar
IPC分类号: B32B27/28 , B32B27/08 , B32B27/30 , B32B27/32 , C08L23/08 , C08L23/10 , C08L25/04 , C08L53/00 , C08L53/02 , C08L77/00 , B29D22/00
CPC分类号: B32B27/08 , B29C47/0021 , B29C47/061 , B32B7/12 , B32B27/302 , B32B27/32 , B32B27/34 , B32B2323/04 , B32B2325/00 , B32B2377/00 , B32B2439/80 , B32B2597/00 , C08L23/08 , C08L23/0815 , C08L23/0846 , C08L23/0853 , C08L23/0869 , C08L23/10 , C08L25/04 , C08L53/00 , C08L53/02 , C08L77/00 , C08L2203/02 , Y10T428/1341 , Y10T428/2495 , Y10T428/2878 , Y10T428/2883 , Y10T428/31743 , Y10T428/31746 , Y10T428/31909 , Y10T428/31913 , Y10T428/31917 , Y10T428/31928 , Y10T428/31931 , Y10T428/31935 , C08L2666/04 , C08L2666/20
摘要: A multiple layer structure comprising a skin layer, a barrier layer, a radio frequency susceptible layer having a first polyolefin in an amount within a range of 30-60% by weight, a second polyolefin in an amount within the range of 25-50% by weight, a radio frequency susceptible polymer in an amount within the range of 3-40% by weight, a styrene and hydrocarbon block copolymer in an amount within the range of 5-40% by weight of the sealant layer.
摘要翻译: 一种多层结构,包括表皮层,阻挡层,具有30-60重量%范围内的第一聚烯烃的射频敏感层,第二聚烯烃的量为25-50重量% ,3-70重量%范围内的无线电频率敏感聚合物,密封剂层重量5-40重量%范围内的苯乙烯和烃嵌段共聚物。
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公开(公告)号:US5993949A
公开(公告)日:1999-11-30
申请号:US975602
申请日:1997-11-21
申请人: Larry Rosenbaum , Steven Giovanetto , Sidney T. Smith , David V. Bacehowski , Gregg Nebgen , Varsha Kalyankar
发明人: Larry Rosenbaum , Steven Giovanetto , Sidney T. Smith , David V. Bacehowski , Gregg Nebgen , Varsha Kalyankar
IPC分类号: B32B27/28 , B32B27/08 , B32B27/30 , B32B27/32 , C08L23/08 , C08L23/10 , C08L25/04 , C08L53/00 , C08L53/02 , C08L77/00
CPC分类号: B32B27/08 , B29C47/0021 , B29C47/061 , C08L23/08 , C08L23/10 , C08L2203/02 , C08L23/0815 , C08L23/0846 , C08L23/0853 , C08L23/0869 , C08L25/04 , C08L53/00 , C08L53/02 , C08L77/00 , Y10T428/1341 , Y10T428/2495 , Y10T428/2878 , Y10T428/2883 , Y10T428/31743 , Y10T428/31746 , Y10T428/31909 , Y10T428/31913 , Y10T428/31917 , Y10T428/31928 , Y10T428/31931 , Y10T428/31935
摘要: A multiple layer structure comprising a skin layer, a barrier layer, a radio frequency susceptible layer having a first polyolefin in an amount within a range of 30-60% by weight, a second polyolefin in an amount within the range of 25-50% by weight, a radio frequency susceptible polymer in an amount within the range of 3-40% by weight, a styrene and hydrocarbon block copolymer in an amount within the range of 5-40% by weight of the sealant layer.
摘要翻译: 一种多层结构,包括表皮层,阻挡层,具有30-60重量%范围内的第一聚烯烃的射频敏感层,第二聚烯烃的量为25-50重量% ,3-70重量%范围内的无线电频率敏感聚合物,密封剂层重量5-40重量%范围内的苯乙烯和烃嵌段共聚物。
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公开(公告)号:US6083587A
公开(公告)日:2000-07-04
申请号:US934924
申请日:1997-09-22
申请人: Sidney T. Smith , Larry Rosenbaum , Steven Giovanetto , Bradley Buchanan , Y. Samuel Ding , Suchuan C. Fan , Gregg Nebgen
发明人: Sidney T. Smith , Larry Rosenbaum , Steven Giovanetto , Bradley Buchanan , Y. Samuel Ding , Suchuan C. Fan , Gregg Nebgen
CPC分类号: B29C47/061 , B32B27/08 , B29C47/0021 , B29C47/0023 , Y10T428/1379 , Y10T428/1383 , Y10T428/26 , Y10T428/28
摘要: The present invention provides a multiple layer structure for fabricating medical products. The layer structure has a core layer of an ethylene vinyl alcohol copolymer having an ethylene content of about 25-45 mole percent, a solution contact layer of a polyolefin positioned on a first side of the core layer, an outer layer positioned on a second side of the core layer opposite the solution contact layer, the outer layer being selected from the group consisting of polyamides, polyesters and polyolefins; two tie layers--one of each adhered to the first and second sides of the core layer and positioned between the solution contact layer and the core layer and between the outer layer and the core layer, and wherein the structure is produced in a cast coextrusion process.
摘要翻译: 本发明提供用于制造医疗产品的多层结构。 层结构具有乙烯含量约25-45摩尔%的乙烯 - 乙烯醇共聚物的芯层,位于芯层第一侧上的聚烯烃的溶液接触层,位于第二侧的外层 所述芯层与所述溶液接触层相对,所述外层选自聚酰胺,聚酯和聚烯烃; 两个粘结层 - 其中一个粘附到芯层的第一和第二侧并且定位在溶液接触层和芯层之间以及外层和芯层之间,并且其中该结构以铸造共挤出工艺 。
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公开(公告)号:US6083584A
公开(公告)日:2000-07-04
申请号:US16236
申请日:1998-01-30
CPC分类号: B65D75/26 , B29C65/02 , B29C66/1122 , B29C66/24244 , B29C66/43 , B29C66/723 , B31B39/00 , B29C65/04 , B29C65/16 , B29C65/18 , B29C66/71 , B29L2031/7128 , B29L2031/7148 , B31B2219/603 , B31B2237/05 , Y10S128/24 , Y10T428/1334 , Y10T428/24777 , Y10T428/24802 , Y10T428/24843 , Y10T428/31917 , Y10T428/3192 , Y10T428/31928
摘要: A container (10) suitable for medical uses comprising a first planar member (18), a second planar member (22), a first seam (24) and a second seam (26). The first planar member (18) is of a multi-layered polymeric material and further comprises a first substrate (38) and a first layer (46). The first layer (46) is disposed on a portion of the first substrate (38) to separately define a first overlap area (58) and an adjacent first peripheral flange (62). The second planar member (22) is of a multi-layered polymeric material. The first seam (24) attaches a portion of the first overlap area (58) to the second planar member (22). The second seam (26) is spaced from the first seam (24) and attaches a portion of the first peripheral flange (62) to the second planar member (22).
摘要翻译: 一种适用于医疗用途的容器(10),包括第一平面构件(18),第二平面构件(22),第一接缝(24)和第二接缝(26)。 第一平面构件(18)是多层聚合材料,并且还包括第一衬底(38)和第一层(46)。 第一层(46)设置在第一基板(38)的一部分上以分开地限定第一重叠区域(58)和相邻的第一周边凸缘(62)。 第二平面构件(22)是多层聚合材料。 第一接缝(24)将第一重叠区域(58)的一部分附接到第二平面构件(22)。 第二接缝(26)与第一接缝(24)间隔开并将第一周边凸缘(62)的一部分附接到第二平面构件(22)。
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公开(公告)号:US06361843B1
公开(公告)日:2002-03-26
申请号:US09607058
申请日:2000-06-29
申请人: Sidney T. Smith , Larry A. Rosenbaum , Steven Giovanetto , Bradley Buchanan , Y. Samuel Ding , Suchuan C. Fan , Gregg Nebgen
发明人: Sidney T. Smith , Larry A. Rosenbaum , Steven Giovanetto , Bradley Buchanan , Y. Samuel Ding , Suchuan C. Fan , Gregg Nebgen
IPC分类号: B32B108
CPC分类号: B32B27/08 , B29C47/0021 , B29C47/0023 , B29C47/061 , B32B27/32 , B32B27/34 , B32B37/153 , B32B2323/046 , B32B2377/00 , B32B2535/00 , Y10T428/1379 , Y10T428/1383 , Y10T428/26 , Y10T428/28 , Y10T428/31725 , Y10T428/3175 , Y10T428/31855 , Y10T428/31909 , Y10T428/3192
摘要: The present invention provides a multiple layer structure (10) for fabricating medical products. The layer structure (10) has a core layer (14) of an ethylene vinyl alcohol copolymer having an ethylene content of about 25-45 mole percent, a solution contact layer of a polyolefin positioned on a first side of the core layer, an outer layer (12) positioned on a second side of the core layer opposite the solution contact layer (16), the outer layer (12) being selected from the group consisting of polyamides, polyesters and polyolefins; two tie layers (18)—one of each adhered to the first and second sides of the core layer (14) and positioned between the solution contact layer (16) and the core layer (14) and between the outer layer (12) and the core layer (14), and wherein the structure (10) is produced in a cast coextrusion process.
摘要翻译: 本发明提供一种用于制造医疗产品的多层结构(10)。 层结构(10)具有乙烯含量约25-45摩尔%的乙烯乙烯醇共聚物的芯层(14),位于芯层第一侧的聚烯烃的溶液接触层,外层 层(12)位于与溶液接触层(16)相对的芯层的第二侧上,外层(12)选自聚酰胺,聚酯和聚烯烃; 两个粘结层(18) - 一个粘合到芯层(14)的第一和第二侧并且位于溶液接触层(16)和芯层(14)之间以及外层(12)和 所述芯层(14),并且其中所述结构(10)以铸造共挤出工艺制造。
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公开(公告)号:US5976300A
公开(公告)日:1999-11-02
申请号:US990503
申请日:1997-12-15
IPC分类号: A61J1/05 , A61J1/10 , B29C65/00 , B29C65/02 , B29C65/04 , B31B19/84 , B32B27/08 , F16L11/04 , B32B31/20 , F16L13/02
CPC分类号: A61J1/10 , B29C65/02 , B29C66/004 , B29C66/3282 , B29C66/3452 , B29C66/53262 , B29C66/73143 , B29C66/8322 , B32B27/08 , F16L11/04 , A61M2207/00 , B29C65/04 , B29C66/71 , B29L2031/7148 , B31B2219/9054
摘要: The present invention provides a method for connecting rounded members between planar members comprising the steps of providing a rounded member having an outer layer having a first melting temperature range and an inner layer concentrically disposed within the outer layer and having a second melting temperature range, the second melting temperature range being warmer than the first melting temperature range, providing a pair of opposed planar members, the planar members each having a melting temperature within the first melting temperature range, positioning an end portion of the rounded member between perimeter edges of the pair of planar members to define an interface area, applying pressure to the interface area to collapse the end portion of the rounded member to essentially a flattened position, applying sealing energy to the interface area to heat the rounded member to a temperature within the first melting temperature range but below the second melting temperature range, thereby forming a weld between the planar members, and the rounded member in the interface area, and, releasing the pressure to the interface area wherein the end portion of the rounded member returns to an open position.
摘要翻译: 本发明提供了一种在平面构件之间连接圆形构件的方法,包括以下步骤:提供具有第一熔化温度范围的外层和同心地设置在外层内并具有第二熔融温度范围的内层的圆形构件, 第二熔化温度范围比第一熔融温度范围更暖,提供一对相对的平面构件,每个平面构件的熔化温度在第一熔融温度范围内,将圆形构件的端部定位在该对的周边边缘之间 的平面构件以限定界面区域,向所述界面区域施加压力以将所述圆形构件的端部折叠到基本上平坦的位置,向所述界面区域施加密封能量以将所述圆形构件加热到所述第一熔化温度 范围但低于第二熔融温度范围,那里 y在所述平面构件和所述接合区域中的所述圆形构件之间形成焊接,并且将所述压力释放到所述圆形构件的端部返回到打开位置的所述界面区域。
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公开(公告)号:US6024220A
公开(公告)日:2000-02-15
申请号:US998256
申请日:1997-12-24
CPC分类号: B65D75/26 , B29C66/1122 , B29C66/133 , B29C66/24244 , B29C66/43 , B29C66/4312 , B29C66/723 , B31B39/00 , B29C65/08 , B29C65/18 , B29C66/53262 , B29C66/71 , B29C66/712 , B29L2031/7128 , B29L2031/7148 , B31B2219/603 , B31B2237/05
摘要: A container is disclosed comprising a first sidewall having a first layer and a second layer. The second layer overlaps a portion of the first layer to define an overlap area. A sealing flange extends from the first layer outward of the overlap area. A second sidewall is connected to the first sidewall along the sealing flange to define an inner chamber therebetween. The second sidewall and the sealing flange define a first layered structure having a first number of layers along the sealing flange. The overlap area and the second sidewall define a second layered structure having a second number of layers. The second number of layers is greater than the first number of layers. The container is sealed by positioning peripheral edges of the first and second sidewalls into registration so that the overlap area is substantially centrally disposed over the second sidewall and applying sealing energy to the first number of layers to define a peripheral seam.
摘要翻译: 公开了一种容器,其包括具有第一层和第二层的第一侧壁。 第二层与第一层的一部分重叠以限定重叠区域。 密封凸缘从重叠区域的外部从第一层延伸。 第二侧壁沿着密封凸缘连接到第一侧壁,以在它们之间限定内室。 第二侧壁和密封凸缘限定了沿着密封凸缘具有第一数量的层的第一分层结构。 重叠区域和第二侧壁限定具有第二层数的第二分层结构。 第二层数大于第一层数。 通过将第一和第二侧壁的外围边缘定位成对准来使容器密封,使得重叠区域基本上居中设置在第二侧壁上方,并且将密封能量施加到第一层数以限定外围接缝。
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