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公开(公告)号：US20120099098A1
公开(公告)日：2012-04-26
申请号：US13265969
申请日：2010-04-23
Applicant: Simon Webster
Inventor： Simon Webster
CPC classification number: G01N21/03 , G01N21/0332 , G01N2021/0346 , G01N2201/0446
Abstract: A unit is provided comprising an array (2) of sample containers (1), said containers, being connected together and arranged in a planar configuration, each container having multiple optically transparent windows arranged such that the sample contained therein can be interrogated using simultaneous multiple optical analytical techniques, the array of containers being configured so as to allow optical access to the windows of each container in the array. Also provided is an apparatus comprising such a unit, a system comprising a combination of such an apparatus and unit and a method of analysing multiple samples by introducing each individual sample into an individual container of such an apparatus, illuminating the samples and detecting and analysing light emerging therefrom.
Abstract translation: 提供了包括样品容器（1）的阵列（2），所述容器连接在一起并布置成平面构造的单元，每个容器具有多个光学透明窗口，其布置使得其中容纳的样品可以使用同时多个 光学分析技术，容器阵列被配置为允许光学访问阵列中每个容器的窗口。 还提供了一种包括这种单元的装置，包括这种装置和单元的组合的系统以及通过将每个单独的样品引入这种装置的单独容器中来分析多个样品的方法，照亮样品并检测和分析光 从中出现。
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公开(公告)号：US08988677B2
公开(公告)日：2015-03-24
申请号：US13265969
申请日：2010-04-23
Applicant: Simon Webster
Inventor： Simon Webster
CPC classification number: G01N21/03 , G01N21/0332 , G01N2021/0346 , G01N2201/0446
Abstract: A unit is provided comprising an array (2) of sample containers (1), said containers, being connected together and arranged in a planar configuration, each container having multiple optically transparent windows arranged such that the sample contained therein can be interrogated using simultaneous multiple optical analytical techniques, the array of containers being configured so as to allow optical access to the windows of each container in the array. Also provided is an apparatus comprising such a unit, a system comprising a combination of such an apparatus and unit and a method of analyzing multiple samples by introducing each individual sample into an individual container of such an apparatus, illuminating the samples and detecting and analyzing light emerging therefrom.
Abstract translation: 提供了包括样品容器（1）的阵列（2），所述容器连接在一起并布置成平面构造的单元，每个容器具有多个光学透明窗口，其布置使得其中容纳的样品可以使用同时多个 光学分析技术，容器阵列被配置为允许光学访问阵列中每个容器的窗口。 还提供了一种包括这种单元的装置，包括这种装置和单元的组合的系统以及通过将每个单独的样品引入这种装置的单独容器中来分析多个样品的方法，照亮样品并检测和分析光 从中出现。
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3.发明申请公开(公告)号：US20130109082A1
公开(公告)日：2013-05-02
申请号：US13639790
申请日：2011-04-08
Applicant: Edward John Quinn , Simon Webster , David Alistair Smith , Robert Harrand
Inventor： Edward John Quinn , Simon Webster , David Alistair Smith , Robert Harrand
CPC classification number: B01L3/502 , B01L2200/16 , B01L2300/0832 , B01L2300/087 , B01L2400/0478 , B01L2400/0481 , G01N35/1002
Abstract: An apparatus for delivering a plurality of liquid volumes sequentially to a reaction site is provided, the apparatus comprising a vessel having a plurality of solid spacers arranged in linear order therein so as to define a series of adjacent voids, separated by individual solid spacers, for receiving said liquid volumes, the vessel being provided in a lateral wall with a plurality of reversibly sealable openings through which the liquid volumes for delivery to the reaction site may be introduced into the voids defined therein, and an outlet port, the spacers being movable within the vessel such that, in use, liquid volumes disposed in the individual voids are deliverable sequentially through the ‘outlet port to the reaction site. Also provided are units, such as disposable cartridge units, comprising such an apparatus coupled to a reaction site and systems comprising such units together with means for interrogating the reaction site to determine the outcome of the reaction.
Abstract translation: 提供了一种用于将多个液体体积顺序地输送到反应部位的装置，该装置包括具有以线性顺序排列的多个固体间隔物的容器，以便限定一系列相邻的空隙，由各个固体间隔物隔开，用于 接收所述液体体积，容器设置在具有多个可逆密封的开口的侧壁中，用于输送到反应部位的液体体积可通过该开口引入到其中限定的空隙中，以及出口，所述间隔件可在 使得在使用中，设置在各个空隙中的液体体积可以依次通过“出口到达反应部位”输送。 还提供了诸如一次性盒单元的单元，其包括耦合到反应位点的这种装置和包含这些单元的系统以及用于询问反应位点以确定反应结果的装置。
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公开(公告)号：US20110134421A1
公开(公告)日：2011-06-09
申请号：US12997506
申请日：2009-06-03
Applicant: Kurt Baldwin , Simon Webster
Inventor： Kurt Baldwin , Simon Webster
CPC classification number: G01J3/44 , G01J3/10 , G01J2001/4242 , G01J2003/4424
Abstract: Raman band detection apparatus illuminates a sample using an illumination source that oscillates in wavelength over a range. The source might for example switch between two wavelengths or might traverse the wavelength range. A wavelength sensitive detector detects radiation emitted by the sample at a series of different wavelengths and a signal processor extracts signals that have a temporal correspondence to the wavelength variation of the illumination at the different wavelengths. One or more Raman bands that might be present will produce a distinctive characteristic of the extracted signals plotted against a spectral axis and relatively simple processing of these spectrally-related time-varying components can then enhance the appearance of the Raman band in a spectral representation based on the processed components. For example, such processing might comprise numerical integration across a spectral plot of the components, or the selection and shifting of certain components, for instance negative components, to overlie others within portions of the spectral representation showing the presence of the Raman band.
Abstract translation: 拉曼带检测装置使用在一定范围内波长振荡的照明源照射样品。 源可以例如在两个波长之间切换或者可以遍历波长范围。 波长敏感检测器以一系列不同波长检测由样本发射的辐射，并且信号处理器提取与不同波长的照明的波长变化具有时间对应关系的信号。 可能存在的一个或多个拉曼带将产生针对光谱轴绘制的提取的信号的独特特性，并且这些光谱相关时变分量的相对简单的处理可以在基于光谱表示的基础上增强拉曼带的出现 对加工组件。 例如，这样的处理可以包括在分量的谱图上的数值积分，或者某些分量（例如负分量）的选择和移位，以覆盖表示拉曼谱带存在的频谱表示的部分内的其他分量。
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