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    Use of a biochip for the diagnosis of sepsis or sepsis related syndrome
    2.
    发明申请
    Use of a biochip for the diagnosis of sepsis or sepsis related syndrome 审中-公开
    使用生物芯片诊断败血症或败血症相关综合征

    公开(公告)号：US20060134685A1

    公开(公告)日：2006-06-22

    申请号：US11349387

    申请日：2006-02-06

    申请人： Peter Zipfel ,  Hans-Peter Saluz ,  Stefan Russwurm ,  Konrad Reinhart

    发明人： Peter Zipfel ,  Hans-Peter Saluz ,  Stefan Russwurm ,  Konrad Reinhart

    IPC分类号： C12Q1/68 ,  C12M1/34

    CPC分类号： C12Q1/6837

    摘要： The application relates to the use of a nucleic acid and/or protein chip comprising probe nucleic acids and/or probe proteins, which are specific for cellular stress, inflammatory and immune reactions, associated with stress, inflammatory and immune reactions, induced during acute phase responses or any combination thereof and which are immobilised on a carrier for the diagnosis of sepsis or sepsis related syndrome.

    摘要翻译： 本申请涉及包含探针核酸和/或探针蛋白的核酸和/或蛋白质芯片在与急性期诱导的应激，炎症和免疫反应相关的细胞应激，炎性和免疫反应特异性的应用 反应或其任何组合，并且其固定在用于诊断败血症或败血症相关综合征的载体上。

    Rapid heat block thermocycler
    5.
    发明授权
    Rapid heat block thermocycler 有权
    快速热块热循环仪

    公开(公告)号：US06556940B1

    公开(公告)日：2003-04-29

    申请号：US09719125

    申请日：2000-12-07

    申请人： Alexandre Tretiakov ,  Hans-Peter Saluz

    发明人： Alexandre Tretiakov ,  Hans-Peter Saluz

    IPC分类号： G01K500

    CPC分类号： B01L3/50851 ,  B01L7/52

    摘要： A heat block thermocycler to perform rapid PCR in multiple small-volume samples (1-20 &mgr;l) employing, low profile, low thermal mass sample block the temperature of which can be rapidly and accurately modulated by a single thermoelectric pump (thermoelectric module). An array of spaced-apart sample wells is formed in the top surface of the block. The samples are placed into the wells of ultrathin-walled (20-40 &mgr;m) multiwell plate and located into the sample block. The heated lid tightly seals the individual wells by pressing the sealing film to the top surface of the multiwell plate. Air pressure arising inside the tightly sealed wells at elevated temperatures deforms the elastic walls of the wells of the ultrathin-walled plate and brings them into close thermal contact with the sample block. A gasket thermally isolates the sample block from the heated lid. The PCR reactions (30 cycles) can be performed in 10-30 minutes.

    摘要翻译： 热块式热循环仪在多个小体积样品（1-20 mul）中进行快速PCR，采用薄型，低热质量样品块，其温度可以通过单个热电泵（热电模块）快速和准确地调制。 在块的顶表面中形成间隔开的样品阱阵列。 将样品置于超薄壁（20-40μm）多孔板的孔中，并置于样品块中。 加热的盖子通过将密封膜压到多孔板的顶表面来紧密地密封各个孔。 在高温下在紧密密封的井内产生的空气压力使超薄壁板的孔的弹性壁变形，使它们与样品块紧密地热接触。 垫片将样品块与加热的盖子隔离。 PCR反应（30个循环）可以在10-30分钟内进行。