公开(公告)号：US07374546B2

公开(公告)日：2008-05-20

申请号：US10767522

申请日：2004-01-29

申请人： Steven N. Roe ,  Charles C. Raney ,  Volker Zimmer ,  Jeffrey N. Roe

发明人： Steven N. Roe ,  Charles C. Raney ,  Volker Zimmer ,  Jeffrey N. Roe

IPC分类号： A61B5/00

CPC分类号： A61B5/14532 ,  A61B5/1486 ,  A61B5/150022 ,  A61B5/150198 ,  A61B5/150213 ,  A61B5/150358 ,  A61B5/150412 ,  A61B5/150564 ,  A61B5/150824 ,  A61B5/15117 ,  A61B5/15144 ,  A61B2562/0295

摘要： An integrated bodily fluid sampling device is used to sample a bodily fluid from an incision in skin. The device includes a lancet for forming the incision in the skin. A housing is coupled to the lancet. The housing defines at least in part a capillary channel with an opening. The capillary channel is sized to draw the bodily fluid from the incision via capillary action. A test strip is positioned along the capillary channel for analyzing the fluid. In one form, a flexible sheet extends from the housing proximal the opening of the capillary channel for drawing the bodily fluid into the opening of the capillary channel. In another form, the lancet is slidably received inside the channel. During lancing, the lancet extends from the housing to form the incision. Fluid from the incision is drawn into the channel and is deposited on the test strip for analysis.

摘要翻译： 一体式体液取样装置用于从皮肤切口取样体液。 该装置包括用于在皮肤中形成切口的刺血针。 外壳与柳叶刀相连。 壳体至少部分地限定具有开口的毛细通道。 毛细通道的大小可以通过毛细管作用从切口中吸取体液。 测试条沿着毛细通道定位，用于分析流体。 在一种形式中，柔性片从靠近毛细通道的开口的壳体延伸，用于将体液吸入毛细通道的开口中。 在另一种形式中，刺血针可滑动地容纳在通道内。 在穿刺期间，柳叶刀从外壳延伸形成切口。 将来自切口的流体吸入通道并沉积在测试条上进行分析。

公开(公告)号：US07476202B2

公开(公告)日：2009-01-13

申请号：US10729546

申请日：2003-12-05

申请人： Charles C. Raney ,  Jeffrey N. Roe ,  A. Michael Jung ,  Chris Wiegel ,  Steven N. Roe ,  Edward P. Perez ,  Rafael C. Donnay ,  David S. Fisher ,  Ian M. Munson

发明人： Charles C. Raney ,  Jeffrey N. Roe ,  A. Michael Jung ,  Chris Wiegel ,  Steven N. Roe ,  Edward P. Perez ,  Rafael C. Donnay ,  David S. Fisher ,  Ian M. Munson

IPC分类号： A61B5/00 ,  B65D81/00

CPC分类号： A61B5/14514 ,  A61B5/14532 ,  A61B5/150022 ,  A61B5/150068 ,  A61B5/150213 ,  A61B5/150358 ,  A61B5/150412 ,  A61B5/150503 ,  A61B5/150755 ,  A61B5/15113 ,  A61B5/15117 ,  A61B5/15128 ,  A61B5/1519 ,  A61B5/15194

摘要： Systems and methods for the sampling of bodily fluid from an incision in the skin include test strips which are positioned adjacent to the skin and which include features to inhibit the passage of the bodily fluid between the skin and the underside of the test strip. One system utilizes a sealing member located on the bottom surface of the test strip and positioned to provide a fluid tight seal with the skin. A second system includes a recessed surface aligned with the inlet opening of the test strip to preclude contact of the bodily fluid directly with the bottom surface of the test strip. A third system involves the use of a hydrophobic surface on the underside of the test strip to inhibit wicking of the bodily fluid along the test strip. The present invention further encompasses the combination of the foregoing sampling systems with each other, and with incising, expressing and/or testing systems and methods, particularly in a single, integrated device.

摘要翻译： 用于从皮肤切口取样体液的系统和方法包括与皮肤相邻定位的测试条，其包括阻止体液在皮肤和测试条的下侧之间通过的特征。 一个系统利用位于测试条的底表面上的密封构件并定位成提供与皮肤的流体密封密封。 第二系统包括与测试条的入口开口对准的凹陷表面，以排除体液直接与测试条的底表面的接触。 第三种系统涉及在测试条的下侧使用疏水性表面以抑制体液沿测试条的芯吸。 本发明还包括上述采样系统的组合，以及切割，表达和/或测试系统和方法，特别是在单个集成设备中。

公开(公告)号：US20100286564A1

公开(公告)日：2010-11-11

申请号：US12840352

申请日：2010-07-21

申请人： Jeffrey N. Roe ,  Steven N. Roe

发明人： Jeffrey N. Roe ,  Steven N. Roe

IPC分类号： A61B5/00

CPC分类号： A61B5/14546 ,  A61B5/1411 ,  A61B5/150022 ,  A61B5/150099 ,  A61B5/150358 ,  A61B5/150419 ,  A61B5/150473 ,  A61B5/150503 ,  A61B5/150633 ,  A61B5/150702 ,  A61B5/150717 ,  A61B5/15113 ,  A61B5/15117 ,  A61B5/1519 ,  A61B5/157 ,  A61B10/0045 ,  A61B2562/0295 ,  G01N33/48 ,  G01N33/48764 ,  G01N2001/028 ,  G01N2035/00019 ,  Y10T436/25

摘要： A bodily fluid sampling device includes a piercing device and a sensor enclosed in a housing. A cassette, which contains test media, is positioned proximal to the sensor so that the sensor is able to analyze a bodily fluid sample collected on the test media. The cassette includes a supply portion from which unused test media is supplied and a storage portion in which contaminated test media is stored after exposure to the bodily fluid. The cassette is adapted to collect a series of bodily fluid samples without requiring disposal of the test media.

公开(公告)号：US08016775B2

公开(公告)日：2011-09-13

申请号：US12581477

申请日：2009-10-19

申请人： Steven N. Roe ,  Jeffrey N. Roe

发明人： Steven N. Roe ,  Jeffrey N. Roe

IPC分类号： A61B5/00 ,  B65D81/00

CPC分类号： A61B5/14532 ,  A61B5/150022 ,  A61B5/150213 ,  A61B5/150358 ,  A61B5/150442 ,  A61B5/150503 ,  A61B5/15142

摘要： An integrated lancing test strip includes a pair of blade members that each have a lancing tip that are configured to lance skin. A pair of spacer members connect the blade members together such that the blade members define an internal capillary. A test strip is positioned along the internal capillary, and the test strip is configured to test analyte levels in the bodily fluid. During use, the lancing tips form one or more incisions in the skin. The fluid from the incisions is drawn via capillary action through the internal capillary and onto the test strip.

摘要翻译： 集成的穿刺测试条包括一对刀片构件，每个刀片构件具有构造成刺穿皮肤的穿刺尖端。 一对间隔件将叶片构件连接在一起，使得叶片构件限定内部毛细管。 测试条沿着内部毛细管定位，并且测试条被配置成测试体液中的分析物水平。 在使用过程中，穿刺尖端在皮肤中形成一个或多个切口。 来自切口的流体通过毛细管作用通过内部毛细管并被拉到测试条上。

公开(公告)号：US07625457B2

公开(公告)日：2009-12-01

申请号：US11619439

申请日：2007-01-03

申请人： Steven N. Roe ,  Jeffrey N. Roe

发明人： Steven N. Roe ,  Jeffrey N. Roe

IPC分类号： A63B39/00 ,  A63B41/00 ,  B29C65/00 ,  B32B37/00

CPC分类号： A61B5/14532 ,  A61B5/150022 ,  A61B5/150213 ,  A61B5/150358 ,  A61B5/150442 ,  A61B5/150503 ,  A61B5/15142

摘要： An integrated lancing test strip includes a pair of blade members that each have a lancing tip that are configured to lance skin. A pair of spacer members connect the blade members together such that the blade members define an internal capillary. A test strip is positioned along the internal capillary, and the test strip is configured to test analyte levels in the bodily fluid. During use, the lancing tips form one or more incisions in the skin. The fluid from the incisions is drawn via capillary action through the internal capillary and onto the test strip.

摘要翻译： 集成的穿刺测试条包括一对刀片构件，每个刀片构件具有构造成刺穿皮肤的穿刺尖端。 一对间隔件将叶片构件连接在一起，使得叶片构件限定内部毛细管。 测试条沿着内部毛细管定位，并且测试条被配置成测试体液中的分析物水平。 在使用过程中，穿刺尖端在皮肤中形成一个或多个切口。 来自切口的流体通过毛细管作用通过内部毛细管并被拉到测试条上。

公开(公告)号：US20120226116A1

公开(公告)日：2012-09-06

申请号：US13466467

申请日：2012-05-08

申请人： Jeffrey N. Roe ,  Steven N. Roe

发明人： Jeffrey N. Roe ,  Steven N. Roe

IPC分类号： A61B5/157 ,  A61B5/1455

CPC分类号： A61B5/14546 ,  A61B5/1411 ,  A61B5/150022 ,  A61B5/150099 ,  A61B5/150358 ,  A61B5/150419 ,  A61B5/150473 ,  A61B5/150503 ,  A61B5/150633 ,  A61B5/150702 ,  A61B5/150717 ,  A61B5/15113 ,  A61B5/15117 ,  A61B5/1519 ,  A61B5/157 ,  A61B10/0045 ,  A61B2562/0295 ,  G01N33/48 ,  G01N33/48764 ,  G01N2001/028 ,  G01N2035/00019 ,  Y10T436/25

摘要： A bodily fluid sampling device includes a piercing device and a sensor enclosed in a housing. A cassette, which contains test media, is positioned proximal to the sensor so that the sensor is able to analyze a bodily fluid sample collected on the test media. The cassette includes a supply portion from which unused test media is supplied and a storage portion in which contaminated test media is stored after exposure to the bodily fluid. The cassette is adapted to collect a series of bodily fluid samples without requiring disposal of the test media.

摘要翻译： 体液采样装置包括穿孔装置和封闭在壳体中的传感器。 包含测试介质的盒子位于传感器的近侧，使得传感器能够分析在测试介质上收集的体液样品。 盒子包括供应部分，从该供应部分供应未使用的试验介质和存储部分，在存储部分中暴露于体液之后存储被污染的测试介质。 该盒适于收集一系列体液样品，而不需要处理测试介质。

公开(公告)号：US07785272B2

公开(公告)日：2010-08-31

申请号：US11283079

申请日：2005-11-18

申请人： Jeffrey N. Roe ,  Steven N. Roe

发明人： Jeffrey N. Roe ,  Steven N. Roe

IPC分类号： A61B5/00 ,  B65D81/00

CPC分类号： A61B5/14546 ,  A61B5/1411 ,  A61B5/150022 ,  A61B5/150099 ,  A61B5/150358 ,  A61B5/150419 ,  A61B5/150473 ,  A61B5/150503 ,  A61B5/150633 ,  A61B5/150702 ,  A61B5/150717 ,  A61B5/15113 ,  A61B5/15117 ,  A61B5/1519 ,  A61B5/157 ,  A61B10/0045 ,  A61B2562/0295 ,  G01N33/48 ,  G01N33/48764 ,  G01N2001/028 ,  G01N2035/00019 ,  Y10T436/25

摘要： A bodily fluid sampling device includes a piercing device and a sensor enclosed in a housing. A cassette, which contains test media, is positioned proximal to the sensor so that the sensor is able to analyze a bodily fluid sample collected on the test media. The cassette includes a supply portion from which unused test media is supplied and a storage portion in which contaminated test media is stored after exposure to the bodily fluid. The cassette is adapted to collect a series of bodily fluid samples without requiring disposal of the test media.

摘要翻译： 体液采样装置包括穿孔装置和封闭在壳体中的传感器。 包含测试介质的盒子位于传感器的近侧，使得传感器能够分析在测试介质上收集的体液样品。 盒子包括供应部分，从该供应部分供应未使用的试验介质和存储部分，在存储部分中暴露于体液之后存储被污染的测试介质。 该盒适于收集一系列体液样品，而不需要处理测试介质。

公开(公告)号：US06285454B1

公开(公告)日：2001-09-04

申请号：US09206641

申请日：1998-12-07

申请人： Joel S. Douglas ,  Jeffrey N. Roe ,  John E. Priest ,  John M. Gleisner ,  Charles C. Raney ,  David A. Hasker ,  Ryszard Radwanski ,  John Ramirez

发明人： Joel S. Douglas ,  Jeffrey N. Roe ,  John E. Priest ,  John M. Gleisner ,  Charles C. Raney ,  David A. Hasker ,  Ryszard Radwanski ,  John Ramirez

IPC分类号： G01N110

CPC分类号： G01N21/8483

摘要： A multi-use assay system accurately docks a removable test strip supporting a reagent-analyte reaction with an optics system including an LED, photodetector, and lenses or light pipes for directing light to and from the test strip. Docking is achieved using alignment fixturing, whereby an optics block holder is relied upon to align the test strip and test pad with the various optical components. Signals from the photodetector indicative of test strip reaction progress are provided to a processor for measuring the analyte.

摘要翻译： 多用分析系统将包含LED，光电检测器和透镜或光管的光学系统的支撑试剂 - 分析物反应的可移除测试条准确地对准，以将光导向和从测试条引导。 使用对准夹具实现对接，由此依靠光学块保持器将测试条和测试垫与各种光学部件对准。 来自光电检测器的指示测试条反应进程的信号被提供给用于测量分析物的处理器。

公开(公告)号：US08986223B2

公开(公告)日：2015-03-24

申请号：US13466467

申请日：2012-05-08

申请人： Jeffrey N. Roe ,  Steven N. Roe

发明人： Jeffrey N. Roe ,  Steven N. Roe

IPC分类号： A61B5/00 ,  B65D81/00 ,  A61B5/145 ,  A61B5/15 ,  G01N33/487 ,  A61B10/00 ,  G01N1/02 ,  G01N35/00

CPC分类号： A61B5/14546 ,  A61B5/1411 ,  A61B5/150022 ,  A61B5/150099 ,  A61B5/150358 ,  A61B5/150419 ,  A61B5/150473 ,  A61B5/150503 ,  A61B5/150633 ,  A61B5/150702 ,  A61B5/150717 ,  A61B5/15113 ,  A61B5/15117 ,  A61B5/1519 ,  A61B5/157 ,  A61B10/0045 ,  A61B2562/0295 ,  G01N33/48 ,  G01N33/48764 ,  G01N2001/028 ,  G01N2035/00019 ,  Y10T436/25

摘要： A bodily fluid sampling device includes a piercing device and a sensor enclosed in a housing. A cassette, which contains test media, is positioned proximal to the sensor so that the sensor is able to analyze a bodily fluid sample collected on the test media. The cassette includes a supply portion from which unused test media is supplied and a storage portion in which contaminated test media is stored after exposure to the bodily fluid. The cassette is adapted to collect a series of bodily fluid samples without requiring disposal of the test media.

公开(公告)号：US08257277B2

公开(公告)日：2012-09-04

申请号：US12848282

申请日：2010-08-02

申请人： Jeffrey N. Roe ,  Steven N. Roe

发明人： Jeffrey N. Roe ,  Steven N. Roe

IPC分类号： A61B5/00 ,  B65D81/00

CPC分类号： A61B5/14546 ,  A61B5/1411 ,  A61B5/150022 ,  A61B5/150099 ,  A61B5/150358 ,  A61B5/150419 ,  A61B5/150473 ,  A61B5/150503 ,  A61B5/150633 ,  A61B5/150702 ,  A61B5/150717 ,  A61B5/15113 ,  A61B5/15117 ,  A61B5/1519 ,  A61B5/157 ,  A61B10/0045 ,  A61B2562/0295 ,  G01N33/48 ,  G01N33/48764 ,  G01N2001/028 ,  G01N2035/00019 ,  Y10T436/25

摘要： A bodily fluid sampling device includes a piercing device and a sensor enclosed in a housing. A cassette, which contains test media, is positioned proximal to the sensor so that the sensor is able to analyze a bodily fluid sample collected on the test media. The cassette includes a supply portion from which unused test media is supplied and a storage portion in which contaminated test media is stored after exposure to the bodily fluid. The cassette is adapted to collect a series of bodily fluid samples without requiring disposal of the test media.

摘要翻译： 体液采样装置包括穿孔装置和封闭在壳体中的传感器。 包含测试介质的盒子位于传感器的近侧，使得传感器能够分析在测试介质上收集的体液样品。 盒子包括供应部分，从该供应部分供应未使用的试验介质和存储部分，在存储部分中暴露于体液之后存储被污染的测试介质。 该盒适于收集一系列体液样品，而不需要处理测试介质。