公开(公告)号：US20160175489A1

公开(公告)日：2016-06-23

申请号：US15056478

申请日：2016-02-29

Applicant: SurModics, Inc.

Inventor： David E. Babcock ,  Timothy M. Kloke ,  Joseph S. McGonigle ,  Nathan Lockwood ,  Bruce Jelle

IPC: A61L29/14 ,  A61L29/08 ,  B05D7/00 ,  C10M107/42 ,  C10M135/36 ,  C10M169/04 ,  A61L29/04 ,  C10M107/28

CPC classification number: A61L29/14 ,  A61L29/041 ,  A61L29/085 ,  A61L2400/10 ,  A61L2420/02 ,  A61L2420/08 ,  B05D7/54 ,  C10M107/28 ,  C10M107/42 ,  C10M107/46 ,  C10M107/48 ,  C10M107/50 ,  C10M135/36 ,  C10M169/04 ,  C10M177/00 ,  C10M2209/084 ,  C10M2209/0845 ,  C10M2217/0245 ,  C10M2217/0285 ,  C10N2220/02 ,  C10N2250/14 ,  C10N2250/141 ,  Y10T428/31573 ,  Y10T428/31699 ,  Y10T428/3175 ,  Y10T428/31928 ,  C10M2217/065 ,  C10M2209/1045 ,  C10M2221/025 ,  C10N2220/021 ,  C08L39/06 ,  C08L33/26 ,  C08L89/00

Abstract: Embodiments of the disclosure include lubricious coatings. In an embodiment the disclosure includes a lubricious coating for a medical device including first and second coated layers. The first coated layer is between the second coated layer and the device surface and includes a vinyl pyrrolidone polymer and a photo reactive group. The second coated layer is in direct contact with the first coated layer and is a top coating that includes an acrylic acid polymer. The second coated layer can optionally include photoreactive groups. The coating was found to have a very low number of particulates (e.g., 10 μm or greater) which is very desirable for in vivo use.

Abstract translation: 本公开的实施方案包括润滑涂层。 在一个实施方案中，本公开包括用于包括第一和第二涂层的医疗装置的润滑涂层。 第一涂层位于第二涂层和装置表面之间，并且包括乙烯基吡咯烷酮聚合物和光反应性基团。 第二涂层与第一涂层直接接触，并且是包括丙烯酸聚合物的顶涂层。 第二涂层可以任选地包括光反应性基团。 发现涂层具有非常低数量的微粒（例如10μm或更大），这对于体内使用是非常理想的。

公开(公告)号：US20170072129A1

公开(公告)日：2017-03-16

申请号：US15257252

申请日：2016-09-06

Applicant: Surmodics, Inc.

Inventor： Joram Slager ,  Joe McGonigle ,  Anh Tri La ,  David E. Babcock ,  Bruce Jelle ,  Aleksey Kurdyumov ,  Timothy M. Kloke ,  Charlie Olson ,  Gary Maharaj ,  Nathan Lockwood

IPC: A61M1/36 ,  A61M39/02 ,  A61M25/10

Abstract: A hemodialysis vascular access device includes a proximal end sized and shaped to sealably couple to a hemodialysis catheter, a movable structure coupled to the proximal end, a fixation structure coupled to the movable region and sized and shaped for fixation on a patient, an elongated sleeve coupled to the fixation structure and sized and shaped for insertion into a patient's vasculature, and a valve at a distal end of the internal lumen. When a hemodialysis catheter is inserted into the device and coupled to the proximal end, distal movement of the proximal end relative to the fixation structure biases a distal end of the hemodialysis catheter from a position inside the elongated sleeve through a valve out of the device and into the patient's blood.

Abstract translation: 血液透析血管通路装置包括尺寸和形状可密封地连接到血液透析导管的近端，耦合到近端的可移动结构，联接到可移动区域的尺寸和形状用于固定在患者身上的细长套筒 耦合到所述固定结构，并且其尺寸和形状用于插入到患者的脉管系统中，以及在所述内腔的远端处的阀。 当血液透析导管插入装置并且联接到近端时，近端相对于固定结构的远端运动通过穿过装置的阀将细胞套筒内的位置偏离血液透析导管的远端， 进入病人的血液。

公开(公告)号：US10980918B2

公开(公告)日：2021-04-20

申请号：US15056478

申请日：2016-02-29

Applicant: SurModics, Inc.

Inventor： David E. Babcock ,  Timothy M. Kloke ,  Joseph S. McGonigle ,  Nathan Lockwood ,  Bruce Jelle

IPC: A61L29/14 ,  A61L29/08 ,  C10M169/04 ,  C10M107/42 ,  A61L29/04 ,  C10M107/48 ,  C10M177/00 ,  C10M107/46 ,  C10M107/50 ,  B05D7/00 ,  C10M107/28 ,  C10M135/36 ,  C10N20/00 ,  C10N50/00

Abstract: Embodiments of the disclosure include lubricious coatings. In an embodiment the disclosure includes a lubricious coating for a medical device including first and second coated layers. The first coated layer is between the second coated layer and the device surface and includes a vinyl pyrrolidone polymer and a photo reactive group. The second coated layer is in direct contact with the first coated layer and is a top coating that includes an acrylic acid polymer. The second coated layer can optionally include photoreactive groups. The coating was found to have a very low number of particulates (e.g., 10 μm or greater) which is very desirable for in vivo use.

公开(公告)号：US11298451B2

公开(公告)日：2022-04-12

申请号：US16685642

申请日：2019-11-15

Applicant: Surmodics, Inc.

Inventor： Joram Slager ,  Joe McGonigle ,  Anh Tri La ,  David E. Babcock ,  Bruce Jelle ,  Aleksey Kurdyumov ,  Timothy M. Kloke ,  Charlie Olson ,  Gary Maharaj ,  Nathan Lockwood

IPC: A61M1/36 ,  A61M25/10 ,  A61M39/02 ,  A61B17/34 ,  A61M25/00 ,  A61M25/06

Abstract: A hemodialysis vascular access device includes a proximal end sized and shaped to sealably couple to a hemodialysis catheter, a movable structure coupled to the proximal end, a fixation structure coupled to the movable region and sized and shaped for fixation on a patient, an elongated sleeve coupled to the fixation structure and sized and shaped for insertion into a patient's vasculature, and a valve at a distal end of the internal lumen. When a hemodialysis catheter is inserted into the device and coupled to the proximal end, distal movement of the proximal end relative to the fixation structure biases a distal end of the hemodialysis catheter from a position inside the elongated sleeve through a valve out of the device and into the patient's blood.

公开(公告)号：US10478546B2

公开(公告)日：2019-11-19

申请号：US15257252

申请日：2016-09-06

Applicant: Surmodics, Inc.

Inventor： Joram Slager ,  Joe McGonigle ,  Anh Tri La ,  David E. Babcock ,  Bruce Jelle ,  Aleksey Kurdyumov ,  Timothy M. Kloke ,  Charlie Olson ,  Gary Maharaj ,  Nathan Lockwood

IPC: A61M5/178 ,  A61M1/36 ,  A61M25/10 ,  A61M39/02 ,  A61B17/34 ,  A61M25/00 ,  A61M25/06

Abstract: A hemodialysis vascular access device includes a proximal end sized and shaped to sealably couple to a hemodialysis catheter, a movable structure coupled to the proximal end, a fixation structure coupled to the movable region and sized and shaped for fixation on a patient, an elongated sleeve coupled to the fixation structure and sized and shaped for insertion into a patient's vasculature, and a valve at a distal end of the internal lumen. When a hemodialysis catheter is inserted into the device and coupled to the proximal end, distal movement of the proximal end relative to the fixation structure biases a distal end of the hemodialysis catheter from a position inside the elongated sleeve through a valve out of the device and into the patient's blood.