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1.发明授权公开(公告)号：US10980918B2
公开(公告)日：2021-04-20
申请号：US15056478
申请日：2016-02-29
Applicant: SurModics, Inc.
Inventor： David E. Babcock , Timothy M. Kloke , Joseph S. McGonigle , Nathan Lockwood , Bruce Jelle
IPC: A61L29/14 , A61L29/08 , C10M169/04 , C10M107/42 , A61L29/04 , C10M107/48 , C10M177/00 , C10M107/46 , C10M107/50 , B05D7/00 , C10M107/28 , C10M135/36 , C10N20/00 , C10N50/00
Abstract: Embodiments of the disclosure include lubricious coatings. In an embodiment the disclosure includes a lubricious coating for a medical device including first and second coated layers. The first coated layer is between the second coated layer and the device surface and includes a vinyl pyrrolidone polymer and a photo reactive group. The second coated layer is in direct contact with the first coated layer and is a top coating that includes an acrylic acid polymer. The second coated layer can optionally include photoreactive groups. The coating was found to have a very low number of particulates (e.g., 10 μm or greater) which is very desirable for in vivo use.
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2.发明申请公开(公告)号：US20210260255A1
公开(公告)日：2021-08-26
申请号：US17316244
申请日：2021-05-10
Applicant: Surmodics, Inc.
Inventor： David E. Babcock , Timothy M. Kloke , Joseph S. McGonigle
IPC: A61L29/14 , A61L29/08 , C10M169/04 , C10M107/42 , A61L29/04 , C10M107/48 , C10M177/00 , C10M107/46 , C10M107/50 , B05D7/00 , C10M107/28 , C10M135/36
Abstract: Embodiments of the disclosure include lubricious coatings. In an embodiment the disclosure includes a lubricious coating for a medical device including first and second coated layers. The first coated layer is between the second coated layer and the device surface and includes a vinyl pyrrolidone polymer and a photo reactive group. The second coated layer is in direct contact with the first coated layer and is a top coating that includes an acrylic acid polymer. The second coated layer can optionally include photoreactive groups. The coating was found to have a very low number of particulates (e.g., 10 μm or greater) which is very desirable for in vivo use.
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3.发明授权公开(公告)号：US11000632B2
公开(公告)日：2021-05-11
申请号：US14148339
申请日：2014-01-06
Applicant: SurModics, Inc.
Inventor： David E. Babcock , Timothy M. Kloke , Joseph S. McGonigle
IPC: A61L29/14 , A61L29/08 , C10M169/04 , C10M107/42 , A61L29/04 , C10M107/48 , C10M177/00 , C10M107/46 , C10M107/50 , B05D7/00 , C10M107/28 , C10M135/36 , C10N20/00 , C10N50/00
Abstract: Embodiments of the disclosure include lubricious coatings. In an embodiment the disclosure includes a lubricious coating for a medical device including first and second coated layers. The first coated layer is between the second coated layer and the device surface and includes a vinyl pyrrolidone polymer and a photo reactive group. The second coated layer is in direct contact with the first coated layer and is a top coating that includes an acrylic acid polymer. The second coated layer can optionally include photoreactive groups. The coating was found to have a very low number of particulates (e.g., 10 μm or greater) which is very desirable for in vivo use.
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4.发明申请LOW PARTICULATE LUBRICIOUS COATING WITH VINYL PYRROLIDONE AND ACIDIC POLYMER-CONTAINER LAYERS 审中-公开低粘度润滑油涂料与乙烯吡咯烷酮和酸性聚合物容器层公开(公告)号：US20160175489A1
公开(公告)日：2016-06-23
申请号：US15056478
申请日：2016-02-29
Applicant: SurModics, Inc.
Inventor： David E. Babcock , Timothy M. Kloke , Joseph S. McGonigle , Nathan Lockwood , Bruce Jelle
IPC: A61L29/14 , A61L29/08 , B05D7/00 , C10M107/42 , C10M135/36 , C10M169/04 , A61L29/04 , C10M107/28
CPC classification number: A61L29/14 , A61L29/041 , A61L29/085 , A61L2400/10 , A61L2420/02 , A61L2420/08 , B05D7/54 , C10M107/28 , C10M107/42 , C10M107/46 , C10M107/48 , C10M107/50 , C10M135/36 , C10M169/04 , C10M177/00 , C10M2209/084 , C10M2209/0845 , C10M2217/0245 , C10M2217/0285 , C10N2220/02 , C10N2250/14 , C10N2250/141 , Y10T428/31573 , Y10T428/31699 , Y10T428/3175 , Y10T428/31928 , C10M2217/065 , C10M2209/1045 , C10M2221/025 , C10N2220/021 , C08L39/06 , C08L33/26 , C08L89/00
Abstract: Embodiments of the disclosure include lubricious coatings. In an embodiment the disclosure includes a lubricious coating for a medical device including first and second coated layers. The first coated layer is between the second coated layer and the device surface and includes a vinyl pyrrolidone polymer and a photo reactive group. The second coated layer is in direct contact with the first coated layer and is a top coating that includes an acrylic acid polymer. The second coated layer can optionally include photoreactive groups. The coating was found to have a very low number of particulates (e.g., 10 μm or greater) which is very desirable for in vivo use.
Abstract translation: 本公开的实施方案包括润滑涂层。 在一个实施方案中，本公开包括用于包括第一和第二涂层的医疗装置的润滑涂层。 第一涂层位于第二涂层和装置表面之间，并且包括乙烯基吡咯烷酮聚合物和光反应性基团。 第二涂层与第一涂层直接接触，并且是包括丙烯酸聚合物的顶涂层。 第二涂层可以任选地包括光反应性基团。 发现涂层具有非常低数量的微粒（例如10μm或更大），这对于体内使用是非常理想的。
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5.发明申请公开(公告)号：US20140004158A1
公开(公告)日：2014-01-02
申请号：US13930512
申请日：2013-06-28
Applicant: SurModics, Inc.
Inventor： Joseph S. McGonigle
IPC: C12N11/06
CPC classification number: C12N11/06 , A61L31/10 , A61L31/16 , A61L2300/25 , A61L2300/252 , A61L2300/64 , A61L2420/08 , C12N2303/00 , C08L71/00 , C08L89/06
Abstract: Cell attachment coatings for articles such as implantable medical devices and cell culture vessels are disclosed. The coatings include an intermediate coater layer which includes a phosphorous-containing component that is bonded in the coating by reacted photoreactive functional groups. The coating also include a second coated layer including an immobilized ECM protein or peptide that includes an active portion of an ECM protein that is able to serve as an outer layer to contact cells during use. The coatings promoted enhanced cell binding and growth.
Abstract translation: 公开了用于诸如可植入医疗装置和细胞培养容器的制品的细胞附着涂层。 涂层包括中间涂布机层，其包括通过反应的光反应性官能团在涂层中结合的含磷组分。 该涂层还包括第二涂层，其包括固定的ECM蛋白或肽，其包括ECM蛋白的活性部分，其能够用作在使用期间接触细胞的外层。 涂层促进增强的细胞结合和生长。
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Patent Agency Ranking
公开(公告)号：US10695174B2
公开(公告)日：2020-06-30
申请号：US15543704
申请日：2016-01-14
Applicant: SURMODICS, INC.
Inventor： Bruce M. Jelle , Joram Slager , Joseph S. McGonigle , Rick Murphy , Andrew G. Bach , Teryl L. Woodwick Sides , Ambereen Angamuthu , Sean Lundquist , Gary Opperman , Nathan A. Lockwood
Abstract: The disclosure provides insertion tools and articles that facilitate entry of a medical device, such as a balloon catheter, into the body. In embodiments the insertion tools have an elongate hollow body (50) that is able to protect a portion of a medical device, such as a balloon of a balloon catheter, during an insertion procedure. In one embodiment the insertion tool has an elongate hollow body (131), a tapered distal end (135), and a locking mechanism (133) at the proximal end which can secure a portion of a balloon catheter. An opening at the distal end can allow passage of the balloon in a folded uninflated state.
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公开(公告)号：US09631190B2
公开(公告)日：2017-04-25
申请号：US13930512
申请日：2013-06-28
Applicant: SurModics, Inc.
Inventor： Joseph S. McGonigle
CPC classification number: C12N11/06 , A61L31/10 , A61L31/16 , A61L2300/25 , A61L2300/252 , A61L2300/64 , A61L2420/08 , C12N2303/00 , C08L71/00 , C08L89/06
Abstract: Cell attachment coatings for articles such as implantable medical devices and cell culture vessels are disclosed. The coatings include an intermediate coater layer which includes a phosphorous-containing component that is bonded in the coating by reacted photoreactive functional groups. The coating also include a second coated layer including an immobilized ECM protein or peptide that includes an active portion of an ECM protein that is able to serve as an outer layer to contact cells during use. The coatings promoted enhanced cell binding and growth.
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公开(公告)号：US11576774B2
公开(公告)日：2023-02-14
申请号：US16914950
申请日：2020-06-29
Applicant: Surmodics, Inc.
Inventor： Bruce M. Jelle , Joram Slager , Joseph S. McGonigle , Rick Murphy , Andrew G. Bach , Teryl L. Woodwick Sides , Ambereen Angamuthu , Sean Lundquist , Gary Opperman , Nathan A. Lockwood
Abstract: The disclosure provides insertion tools and articles that facilitate entry of a medical device, such as a balloon catheter, into the body. In embodiments the insertion tools have an elongate hollow body (50) that is able to protect a portion of a medical device, such as a balloon of a balloon catheter, during an insertion procedure. In one embodiment the insertion tool has an elongate hollow body (131), a tapered distal end (135), and a locking mechanism (133) at the proximal end which can secure a portion of a balloon catheter. An opening at the distal end can allow passage of the balloon in a folded uninflated state.
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公开(公告)号：US20210015613A1
公开(公告)日：2021-01-21
申请号：US16914950
申请日：2020-06-29
Applicant: Surmodics, Inc.
Inventor： Bruce M. Jelle , Joram Slager , Joseph S. McGonigle , Rick Murphy , Andrew G. Bach , Teryl L. Woodwick Sides , Ambereen Angamuthu , Sean Lundquist , Gary Opperman , Nathan A. Lockwood
Abstract: The disclosure provides insertion tools and articles that facilitate entry of a medical device, such as a balloon catheter, into the body. In embodiments the insertion tools have an elongate hollow body (50) that is able to protect a portion of a medical device, such as a balloon of a balloon catheter, during an insertion procedure. In one embodiment the insertion tool has an elongate hollow body (131), a tapered distal end (135), and a locking mechanism (133) at the proximal end which can secure a portion of a balloon catheter. An opening at the distal end can allow passage of the balloon in a folded uninflated state.
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公开(公告)号：US20170367824A1
公开(公告)日：2017-12-28
申请号：US15543704
申请日：2016-01-14
Applicant: SURMODICS, INC.
Inventor： Bruce M. Jelle , Joram Slager , Joseph S. McGonigle , Rick Murphy , Andrew G. Bach , Teryl L. Woodwick Sides , Ambereen Angamuthu , Sean Lundquist , Gary Opperman , Nathan A. Lockwood
CPC classification number: A61F2/2433 , A61M25/0102 , A61M25/0668 , A61M25/09041 , A61M25/10 , A61M2025/0681 , A61M2025/1081
Abstract: The disclosure provides insertion tools and articles that facilitate entry of a medical device, such as a balloon catheter, into the body. In embodiments the insertion tools have an elongate hollow body (50) that is able to protect a portion of a medical device, such as a balloon of a balloon catheter, during an insertion procedure. In one embodiment the insertion tool has an elongate hollow body (131), a tapered distal end (135), and a locking mechanism (133) at the proximal end which can secure a portion of a balloon catheter. An opening at the distal end can allow passage of the balloon in a folded uninflated state.
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