METHODS AND SYSTEMS FOR ENDOBRONCHIAL DIAGNOSTICS
    1.
    发明申请
    METHODS AND SYSTEMS FOR ENDOBRONCHIAL DIAGNOSTICS 有权
    内分泌诊断的方法与系统

    公开(公告)号:US20120149995A1

    公开(公告)日:2012-06-14

    申请号:US13174633

    申请日:2011-06-30

    摘要: Methods and systems for targeting, accessing and diagnosing diseased lung compartments are disclosed. The method comprises introducing a diagnostic catheter with an occluding member at its distal end into a lung segment via an assisted ventilation device; inflating the occluding member to isolate the lung segment; and performing a diagnostic procedure with the catheter while the patient is ventilated. The proximal end of the diagnostic catheter is configured to be attached to a console. The method may also comprise introducing the diagnostic catheter into the lung segment; inflating the occluding member to isolate the lung segment; and monitoring blood oxygen saturation. The method may further comprise introducing the diagnostic catheter into the lung segment; determining tidal flow volume in the lung segment; determining total lung capacity of the patient; and determining a flow rank value based on the tidal flow volume of the lung segment and the total lung capacity.

    摘要翻译: 公开了用于靶向,访问和诊断患病肺隔室的方法和系统。 该方法包括通过辅助通气装置将具有阻塞构件的诊断导管在其远端引入肺段; 使闭塞部件膨胀以分离肺段; 并且在患者通气时用导管执行诊断程序。 诊断导管的近端被配置为附接到控制台。 该方法还可以包括将诊断导管引入肺段中; 使闭塞部件膨胀以分离肺段; 并监测血氧饱和度。 该方法还可以包括将诊断导管引入肺部段中; 确定肺段的潮汐流量; 确定患者的总肺容量; 并且基于肺段的潮汐流量和总肺容量来确定流量值。

    Methods and systems for endobronchial diagnostics
    2.
    发明授权
    Methods and systems for endobronchial diagnostics 有权
    支气管内诊断的方法和系统

    公开(公告)号:US08808194B2

    公开(公告)日:2014-08-19

    申请号:US13174633

    申请日:2011-06-30

    IPC分类号: A61B5/08

    摘要: Methods and systems for targeting, accessing and diagnosing diseased lung compartments are disclosed. The method comprises introducing a diagnostic catheter with an occluding member at its distal end into a lung segment via an assisted ventilation device; inflating the occluding member to isolate the lung segment; and performing a diagnostic procedure with the catheter while the patient is ventilated. The proximal end of the diagnostic catheter is configured to be attached to a console. The method may also comprise introducing the diagnostic catheter into the lung segment; inflating the occluding member to isolate the lung segment; and monitoring blood oxygen saturation. The method may further comprise introducing the diagnostic catheter into the lung segment; determining tidal flow volume in the lung segment; determining total lung capacity of the patient; and determining a flow rank value based on the tidal flow volume of the lung segment and the total lung capacity.

    摘要翻译: 公开了用于靶向,访问和诊断患病肺隔室的方法和系统。 该方法包括通过辅助通气装置将具有阻塞构件的诊断导管在其远端引入肺段; 使闭塞部件膨胀以分离肺段; 并且在患者通气时用导管执行诊断程序。 诊断导管的近端被配置为附接到控制台。 该方法还可以包括将诊断导管引入肺段中; 使闭塞部件膨胀以分离肺段; 并监测血氧饱和度。 该方法还可以包括将诊断导管引入肺部段中; 确定肺段的潮汐流量; 确定患者的总肺容量; 并且基于肺段的潮汐流量和总肺容量来确定流量值。

    METHODS AND SYSTEMS FOR ENDOBRONCHIAL DIAGNOSTICS
    4.
    发明申请
    METHODS AND SYSTEMS FOR ENDOBRONCHIAL DIAGNOSTICS 审中-公开
    内分泌诊断的方法与系统

    公开(公告)号:US20110295141A1

    公开(公告)日:2011-12-01

    申请号:US12954499

    申请日:2010-11-24

    IPC分类号: A61B5/08

    CPC分类号: A61B5/082

    摘要: A method for assessing lung function in a patient is disclosed. The method comprises isolating a lung compartment. Thereafter, in one embodiment, an inhaled gas of known composition is introduced into the lung and compared to the composition of the exhaled gas. Alternatively, accumulated CO2 content is measured within the isolated lung compartment over time, and compared to a baseline CO2 content. Alternatively, a change in pressure of an isolated lung compartment may be monitored. Alternatively, the magnitude of the range of CO2 values in an isolated lung compartment can be compared to a predetermined threshold. Any of the results obtained via these alternative embodiments may be used to determine lung function.

    摘要翻译: 公开了一种用于评估患者的肺功能的方法。 该方法包括分离肺隔室。 此后,在一个实施方案中,将已知组合物的吸入气体引入肺中并与呼出气体的组成进行比较。 或者,随着时间的推移在隔离的肺隔室内测量累积的CO 2含量,并与基线CO 2含量进行比较。 或者,可以监测隔离的肺隔室的压力变化。 或者,可以将隔离的肺隔室中的CO 2值的范围的大小与预定阈值进行比较。 通过这些替代实施方案获得的任何结果可用于确定肺功能。

    MEASURING LUNG FUNCTION AND LUNG DISEASE PROGRESSION AT A LOBAR/SEGMENTAL LEVEL
    6.
    发明申请
    MEASURING LUNG FUNCTION AND LUNG DISEASE PROGRESSION AT A LOBAR/SEGMENTAL LEVEL 有权
    测量肺功能和肺功能障碍进展

    公开(公告)号:US20110313307A1

    公开(公告)日:2011-12-22

    申请号:US12964515

    申请日:2010-12-09

    IPC分类号: A61B5/085

    摘要: A method for determining lung function in a patient is disclosed, in which a multi-lumen catheter with an expandable occluding element at its end is used to isolate a targeted lung compartment, and respiratory characteristics at the targeted lung compartment are measured over multiple respiratory cycles. The relation between various characteristics of the respiratory cycle is used to determine compliance of lung tissue within the targeted lung compartment.

    摘要翻译: 公开了一种用于确定患者的肺功能的方法,其中使用其末端具有可扩张闭塞元件的多腔导管来分离靶向的肺隔室,并且在多个呼吸循环中测量目标肺隔室处的呼吸特征 。 呼吸周期的各种特征之间的关系用于确定目标肺隔室内肺组织的依从性。

    Devices and systems for lung treatment
    7.
    发明授权
    Devices and systems for lung treatment 有权
    用于肺部治疗的装置和系统

    公开(公告)号:US09592008B2

    公开(公告)日:2017-03-14

    申请号:US13174565

    申请日:2011-06-30

    IPC分类号: A61B5/00 A61B5/107

    摘要: Devices, systems, and methods for measuring the diameter of an airway in a human or animal subject are disclosed. The device comprises a flexible catheter body having a proximal end and a distal end. Flexible sizing elements are disposed along and extend approximately orthogonally from the catheter body. The sizing elements have different heights from one another and are configured to fit through the working channel of a bronchoscope. Devices, systems, and methods for redirecting airflow through a lung airway are also disclosed. The method comprises introducing into the airway a catheter comprising a distal end, a proximal end and an elongated portion therebetween, wherein the distal end comprises an airway closing mechanism, and wherein the proximal end comprises an actuator to actuate the airway closing mechanism; and actuating the airway closing mechanism to at least partially close the airway.

    摘要翻译: 公开了用于测量人或动物受试者中气道直径的装置,系统和方法。 该装置包括具有近端和远端的柔性导管本体。 灵活的施胶元件沿导管本体大致正交地设置并延伸。 尺寸调节元件彼此具有不同的高度,并且被配置成穿过支气管镜的工作通道。 还公开了用于将气流重定向通过肺气道的装置,系统和方法。 该方法包括将包括远端,近端和其间的细长部分的导管引入气道中,其中远端包括气道关闭机构,并且其中近端包括用于致动气道闭合机构的致动器; 并且致动气道关闭机构以至少部分地关闭气道。

    LOCAL LUNG MEASUREMENT AND TREATMENT
    8.
    发明申请
    LOCAL LUNG MEASUREMENT AND TREATMENT 审中-公开
    当地的肺部测量和治疗

    公开(公告)号:US20110301483A1

    公开(公告)日:2011-12-08

    申请号:US12963412

    申请日:2010-12-08

    IPC分类号: A61B5/097 A61B5/091 A61B5/08

    摘要: A method of determining potential treatment sites in a diseased lung is disclosed, in which an assessment catheter is introduced into a lung passageway. The catheter has a distal portion comprising an occluding member and a proximal portion configured to operatively mate with an external console. The catheter is used to identify one or more assessment sites within the airways of the lung. At each assessment site, at least one physiological, anatomical or biological characteristic is determined. A characteristic score for each assessment site is calculated based on a predetermined algorithm; and a treatment is determined based on the scores of the assessment sites. The algorithm takes into account several parameters including the disease characteristics as well as the number and proximity of each assessment site to at least one of the diseased regions. The method envisages treatment of emphysema, asthma or bronchopleural leak.

    摘要翻译: 公开了一种确定患病肺中潜在治疗部位的方法,其中将评估导管引入肺通道。 该导管具有远端部分,该远端部分包括封闭构件和配置成与外部控制台可操作地配合的近端部分。 导管用于识别肺气道内的一个或多个评估部位。 在每个评估部位,确定至少一个生理,解剖或生物特征。 基于预定算法计算每个评估点的特征得分; 并且基于评估地点的分数来确定治疗。 该算法考虑了几个参数,包括疾病特征以及每个评估位点与至少一个患病区域的数量和接近程度。 该方法设想治疗肺气肿,哮喘或支气管胸膜泄漏。

    DEVICES AND SYSTEMS FOR LUNG TREATMENT
    9.
    发明申请
    DEVICES AND SYSTEMS FOR LUNG TREATMENT 有权
    用于肺部治疗的设备和系统

    公开(公告)号:US20120149978A1

    公开(公告)日:2012-06-14

    申请号:US13174565

    申请日:2011-06-30

    IPC分类号: A61B1/267 A61B1/018

    摘要: Devices, systems, and methods for measuring the diameter of an airway in a human or animal subject are disclosed. The device comprises a flexible catheter body having a proximal end and a distal end. Flexible sizing elements are disposed along and extend approximately orthogonally from the catheter body. The sizing elements have different heights from one another and are configured to fit through the working channel of a bronchoscope. Devices, systems, and methods for redirecting airflow through a lung airway are also disclosed. The method comprises introducing into the airway a catheter comprising a distal end, a proximal end and an elongated portion therebetween, wherein the distal end comprises an airway closing mechanism, and wherein the proximal end comprises an actuator to actuate the airway closing mechanism; and actuating the airway closing mechanism to at least partially close the airway.

    摘要翻译: 公开了用于测量人或动物受试者中气道直径的装置,系统和方法。 该装置包括具有近端和远端的柔性导管本体。 灵活的施胶元件沿导管本体大致正交地设置并延伸。 尺寸调节元件彼此具有不同的高度,并且被配置成穿过支气管镜的工作通道。 还公开了用于将气流重定向通过肺气道的装置,系统和方法。 该方法包括将包括远端,近端和其间的细长部分的导管引入气道中,其中远端包括气道关闭机构,并且其中近端包括用于致动气道闭合机构的致动器; 并且致动气道关闭机构以至少部分地关闭气道。