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公开(公告)号：US20100058480A1
公开(公告)日：2010-03-04
申请号：US12373545
申请日：2006-07-13
CPC分类号： A61N1/37211 , A61B5/0402 , A61B5/6843 , A61N1/37282 , G16H40/63
摘要： An implantable medical device that is physically connectable to the body of a user has an information manager that manages sensitive information associated with the user or the device. A sensor is connected to the device that senses whether the device is physically connected to the body of the user, and generates a signal indicating whether the device is actually connected to the body of the user. The information manager is connected to the sensor, and is responsive to the sensor signal so as to perform information managing functions based on the signal. Among other things, fraudulent retrieval of sensitive data from the device is prevented if the device is not connected to or implanted in the body of the user.
摘要翻译： 物理上可连接到用户身体的可植入医疗设备具有管理与用户或设备相关联的敏感信息的信息管理器。 感测器连接到感测设备物理连接到用户身体的设备，并且产生指示设备是否实际连接到用户身体的信号。 信息管理器连接到传感器，并响应于传感器信号，以便根据信号执行信息管理功能。 除此之外，如果设备未连接到或植入用户的身体，则防止来自设备的敏感数据的欺诈性检索。
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2.发明申请A MEDICAL SYSTEM AND A METHOD FOR DETERMINING SETTINGS OF AN IMPLANTABLE DEVICE (As Amended) 有权一种用于确定可植入装置的设置的医疗系统和方法（如修改）公开(公告)号：US20100106212A1
公开(公告)日：2010-04-29
申请号：US12442742
申请日：2006-09-25
CPC分类号： A61N1/36585 , A61N1/025 , A61N1/3682 , A61N1/37247 , A61N1/37252 , G06F19/00 , G16H40/40
摘要： In a medical system and a method for operating such a system, the system includes an implantable medical device of a patient, a programmer device, and an extracorporeal stress equipment adapted to exert a physiological stress on the patient, for automatically determining settings of a sensor for sensing a physiological parameter of the patient or for automatically determining a pacing setting of the device over a broad range of workloads of the equipment. The ingoing units and/or devices of the medical system, i.e. the implantable medical device of the patient, the programmer device, and the extracorporeal stress equipment, communicate bi-directionally with each other and form a closed loop.
摘要翻译： 在用于操作这种系统的医疗系统和方法中，系统包括患者的可植入医疗装置，编程器装置和适于对患者施加生理压力的体外应力装置，用于自动确定传感器的设置 用于感测患者的生理参数或用于在设备的广泛工作负载上自动确定设备的起搏设置。 医疗系统的进入单元和/或装置，即患者的可植入医疗装置，编程器装置和体外应力设备彼此双向地通信并形成闭环。
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3.发明授权Medical system and a method for determining settings of an implantable device 有权医疗系统和用于确定可植入装置的设置的方法公开(公告)号：US08359095B2
公开(公告)日：2013-01-22
申请号：US12442742
申请日：2006-09-25
CPC分类号： A61N1/36585 , A61N1/025 , A61N1/3682 , A61N1/37247 , A61N1/37252 , G06F19/00 , G16H40/40
摘要： In a medical system and a method for operating such a system, the system includes an implantable medical device of a patient, a programmer device, and an extracorporeal stress equipment adapted to exert a physiological stress on the patient, for automatically determining settings of a sensor for sensing a physiological parameter of the patient or for automatically determining a pacing setting of the device over a broad range of workloads of the equipment. The ingoing units and/or devices of the medical system, i.e. the implantable medical device of the patient, the programmer device, and the extracorporeal stress equipment, communicate bi-directionally with each other and form a closed loop.
摘要翻译： 在用于操作这种系统的医疗系统和方法中，系统包括患者的可植入医疗装置，编程器装置和适于对患者施加生理压力的体外应力装置，用于自动确定传感器的设置 用于感测患者的生理参数或用于在设备的广泛工作负载上自动确定设备的起搏设置。 医疗系统的进入单元和/或装置，即患者的可植入医疗装置，编程器装置和体外应力设备彼此双向地通信并形成闭环。
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4.发明申请IMPLANTABLE MEDICAL DEVICE SYSTEM AND METHOD FOR ADAPTING FUNCTIONS OF THE CLINICIAN'S WORKSTATION THEREOF 审中-公开可植入医疗装置系统及其适应临床工作站功能的方法公开(公告)号：US20090187426A1
公开(公告)日：2009-07-23
申请号：US12301691
申请日：2006-05-31
CPC分类号： A61N1/37282 , G06F19/3418 , G06Q50/24
摘要： Functions of a clinician's workstation, which is a part of an implantable medical system that also includes an implantable medical device, are dynamically adapted dependent on collected patient data and/or collected data relating to operation of the implantable medical device. The adaptation can take place based on instructions provided to the workstation from a server, that is supplied with the collected data, and that processes the collected data to produce the instructions.
摘要翻译： 根据收集的患者数据和/或与可植入医疗装置的操作相关的收集数据，临床医生工作站的功能也是植入式医疗系统的一部分，其也包括可植入医疗装置。 适应可以基于从服务器提供给工作站的指令进行，该指令被提供给所收集的数据，并且处理收集的数据以产生指令。
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公开(公告)号：US09162066B2
公开(公告)日：2015-10-20
申请号：US13508968
申请日：2011-05-31
CPC分类号： A61N1/368 , A61N1/3622 , A61N1/3682 , A61N1/3684
摘要： A first ventricle is stimulated at a stimulation site, a point of time for arrival at the AV node for at least one depolarization wave resulting from the stimulation is estimated and a first activation time interval substantially corresponding to the time interval required for at least one depolarization wave to travel from the stimulation site in the first ventricle to the AV node is computed. A similar process is used to compute a second activation time interval for the other ventricle. Based on these activation time intervals and a difference between the intervals, a pacing therapy can be determined.
摘要翻译： 在刺激部位刺激第一脑室，估计从刺激产生的至少一个去极化波到达AV节点的时间点，并且基本对应于至少一个去极化所需的时间间隔的第一激活时间间隔 计算从第一脑室的刺激部位到AV节点的波。 使用类似的过程来计算另一个心室的第二激活时间间隔。 基于这些激活时间间隔和间隔之间的差异，可以确定起搏治疗。
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公开(公告)号：US20120310296A1
公开(公告)日：2012-12-06
申请号：US13471167
申请日：2012-05-14
申请人： Kjell Noren , Anders Bjorling , Tomas Svensson , Sven-Erik Hedberg , Allen Keel , Stuart Rosenberg , Kyungmoo Ryu
发明人： Kjell Noren , Anders Bjorling , Tomas Svensson , Sven-Erik Hedberg , Allen Keel , Stuart Rosenberg , Kyungmoo Ryu
IPC分类号： A61N1/365
CPC分类号： A61N1/36507 , A61N1/3682 , A61N1/3684 , A61N1/37252
摘要： CRT settings for an implantable medical device are determined by applying pacing pulses to heart chambers of a scheme of different combinations of interchamber delays. A respective width parameter value representing an R or P wave width is determined for each such delay combination based on an ECG representing signal and the width parameter values are employed to estimate a parametric model defining the width parameter as a function of interchamber delays. Candidate interchamber delays that minimize the width parameter are determined from the parametric model and employed to determine optimal CRT settings. The technique provides an efficient way of finding optimal CRT settings when multiple pacing sites are available in a heart chamber.
摘要翻译： 用于可植入医疗装置的CRT设置通过将不同组合的车间延迟的方案应用于心室来进行起搏脉冲来确定。 基于ECG表示信号为每个这样的延迟组合确定表示R或P波宽的相应宽度参数值，并且使用宽度参数值来估计定义作为间歇延迟的函数的宽度参数的参数模型。 从参数模型中确定最小化宽度参数的候选车间延迟，并用于确定最佳CRT设置。 该技术提供了一种在心室中可用多个起搏部位时可以找到最佳CRT设置的有效方式。
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7.发明授权Implantable medical device and a method comprising means for detecting and classifying ventricular tachyarrhythmias 有权植入式医疗装置和包括用于检测和分类室性快速性心律失常的装置的方法公开(公告)号：US08321016B2
公开(公告)日：2012-11-27
申请号：US12602533
申请日：2007-06-13
CPC分类号： A61N1/3702 , A61B5/0464 , A61B5/053 , A61B5/7264
摘要： In a method and implantable medical device for ventricular tachyarrhythmia detection and classification, upon detection of a ventricular tachyarrhythmia based on an electrocardiogram signal, cardiogenic impedance data representative of ventricular volume dynamics are collected and used for classifying the detected tachyarrhythmia as stable or unstable. In the latter case but typically not in the former case, defibrillation shocks or other forms of therapy are applied to combat the unstable ventricular tachyarrhythmia.
摘要翻译： 在用于室性快速性心律失常检测和分类的方法和可植入医疗装置中，在基于心电图信号检测到心室快速性心律失常时，收集表示心室容积动力学的心源阻抗数据，并用于将检测到的心律失常分类为稳定或不稳定。 在后一种情况下，但通常不是在前一种情况下，应用除颤电击或其他形式的治疗来对抗不稳定性室性快速性心律失常。
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公开(公告)号：US20110319769A1
公开(公告)日：2011-12-29
申请号：US13255460
申请日：2009-03-13
CPC分类号： A61B5/0452 , A61B5/026 , A61B5/053 , A61B5/1116 , A61B5/1118 , A61B5/4836 , A61B5/6846 , A61B5/7405 , A61B5/7455 , A61N1/3702
摘要： An ischemia monitoring system has detectors for detecting the onset of an ischemic event of a tissue in subject, the end of the ischemic event and the end of a following recovery from the ischemic event, respectively. A time processor determines the duration of the ischemic event and the recovery period based on the detected onset and end times. A status processor co-processes the two determined time durations for the purpose of monitoring the ischemic status of the subject and detecting any deterioration in ischemic status for the latest ischemic event as compared to previous ischemic events that have occurred in the subject's tissue.
摘要翻译： 缺血监测系统具有检测器，用于分别检测受试者组织的缺血事件的发作，缺血事件的结束以及从缺血事件中恢复的结束。 时间处理器基于检测到的开始和结束时间来确定缺血事件的持续时间和恢复期。 状态处理器协调处理两个确定的持续时间以便监测受试者的缺血状态并且检测与在受试者组织中发生的先前缺血事件相比，最新缺血事件的缺血状态的任何恶化。
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9.发明申请IMPLANTABLE HEART STIMULATOR FOR MEASURING DYSSYNCHRONY USING IMPEDANCE 有权用于测量使用阻抗的DYSSYNCHRONY的可植入心脏刺激仪公开(公告)号：US20100298904A1
公开(公告)日：2010-11-25
申请号：US12863381
申请日：2008-01-28
IPC分类号： A61N1/365
CPC分类号： A61N1/36521 , A61B5/053 , A61B5/0538 , A61N1/3684
摘要： Implantable heart stimulator connectable to an electrode arrangement has a pulse generator adapted to deliver stimulation pulses to a heart of a subject; an impedance measurement unit adapted monitor at least one heart chamber of the heart of the subject to measure the impedance in the at least one monitored heart chamber for generating an impedance signal corresponding to the measured impedance. The impedance signal is applied to a processor where the signal is processed, according to specified criteria, and a fractionation index value is determined represented by the curve length of the impedance signal during a predetermined measurement period. The fractionation index value is a measure of different degrees of mechanical dyssynchrony of the heart.
摘要翻译： 可连接到电极装置的可植入心脏刺激器具有适于将刺激脉冲输送到受试者心脏的脉冲发生器; 阻抗测量单元适于监测所述受试者心脏的至少一个心室，以测量所述至少一个监测的心室中的阻抗，以产生对应于所测量的阻抗的阻抗信号。 根据规定的标准，将阻抗信号施加到处理器，信号被处理，并且在预定测量期间由阻抗信号的曲线长度确定分数指数值。 分离指数值是心脏不同程度的机械不同步的度量。
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10.发明申请PIEZOELECTRIC SENSOR, A METHOD FOR MANUFACTURING A PIEZOELECTRIC SENSOR AND A MEDICAL IMPLANTABLE LEAD COMPRISING SUCH A PIEZOELECTRIC SENSOR 有权压电传感器，制造压电传感器的方法和包含这种压电传感器的医用可植入引线公开(公告)号：US20100010600A1
公开(公告)日：2010-01-14
申请号：US12298218
申请日：2006-04-25
申请人： Tom Eriksson , Kenth Nilsson , Sven-Erik Hedberg
发明人： Tom Eriksson , Kenth Nilsson , Sven-Erik Hedberg
CPC分类号： A61N1/056 , A61B5/0215 , A61N1/0565 , A61N1/36542 , A61N1/36564 , G01L9/0026 , G01L9/08 , H01L41/087 , H01L41/1132
摘要： In a piezoelectric sensor, a method for the manufacture thereof, and an implantable lead embodying such a piezoelectric sensor, a layer of piezoelectric material, having aligned, polarized dipoles, is applied to a tubular supporting substrate, the layer of piezoelectric material having at least one electrode at an outer surface thereof and at least one electrode at an inner surface thereof. The piezoelectric material is applied on the inner circumference of the tubular supporting substrate.
摘要翻译： 在压电传感器中，其制造方法以及体现这种压电传感器的可植入引线，具有排列的极化偶极子的压电材料层被施加到管状支撑衬底，压电材料层至少具有 一个电极在其外表面和至少一个电极在其内表面。 压电材料被施加在管状支撑衬底的内圆周上。
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