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公开(公告)号：US11951232B2
公开(公告)日：2024-04-09
申请号：US16903920
申请日：2020-06-17
Applicant: THE CLEVELAND CLINIC FOUNDATION
Inventor： Kathleen Derwin , Amit Aurora , Joseph P. Iannotti , Jesse A. McCarron
CPC classification number: A61L27/3633 , A61F2/08 , A61L27/40 , A61L27/54 , A61F2/0063 , A61L27/3604
Abstract: One aspect of the present disclosure can include a biocompatible tissue graft. The graft can include an extracellular matrix (ECM) patch or strip and at least one fiber stitched into the ECM patch or strip in a peripheral reinforcement pattern. The at least one fiber can have opposing terminal ends. The at least one fiber can mitigate tearing and/or improve fixation retention of the ECM patch or strip. The at least one fiber can comprise a plurality of interconnected stitches. The opposing terminal ends of the at least one fiber can be stitched together to form a continuous stitching construction.
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公开(公告)号：US20220331058A1
公开(公告)日：2022-10-20
申请号：US17854597
申请日：2022-06-30
Applicant: VISCUS BIOLOGICS, LLC , THE CLEVELAND CLINIC FOUNDATION
Inventor： Justin Jeffrey Baker , Peter Hayes Gingras , Robert Priest , Kathe Derwin , Joseph P. Iannotti , Sambit Sahoo , Andrew Ryan Baker
IPC: A61B90/00
Abstract: A fiber-based radiopaque tissue marker for radiographic marking of tissue is provided. The marker is a sterile, single-patient-use polymeric fiber with a radiopaque material and a dye. The marker is radiopaque using standard radiographs such as x-rays and mammography. The marker can also be visualized by low-dose CT scans.
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公开(公告)号：US09326781B2
公开(公告)日：2016-05-03
申请号：US14628781
申请日：2015-02-23
Applicant: THE CLEVELAND CLINIC FOUNDATION
Inventor： Joseph P. Iannotti , Wael K. Barsoum , Jason A. Bryan
CPC classification number: A61B17/1739 , A61B17/15 , A61B17/1703 , A61B17/1778 , A61B2017/568 , A61F2/46 , A61F2/4612 , A61F2002/4635 , A61F2002/4687
Abstract: An apparatus for providing a reference indication to a patient tissue includes a primary locating block having a patient-specific primary mating surface contoured for mating contact with a portion of the patient tissue in a predetermined primary mating orientation custom-configured responsive to preoperative imaging of the patient tissue. At least one mounting feature is provided to the primary locating block. At least one secondary item is configured for selective engagement with the primary locating block. The secondary item is at least one of a noncustomized secondary item and a patient-specific secondary item. The secondary item provides a reference indication to at least a portion of the patient tissue. The mounting feature of the primary locating block is configured for engagement with at least one secondary item in a predetermined secondary mounting relationship. The secondary mounting relationship is custom-configured for the patient tissue responsive to preoperative imaging of the patient tissue.
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公开(公告)号：US20160106459A1
公开(公告)日：2016-04-21
申请号：US14955103
申请日：2015-12-01
Applicant: THE CLEVELAND CLINIC FOUNDATION
Inventor： Kathleen A. Derwin , Joseph P. Iannotti , Ryan A. Milks
CPC classification number: A61B17/3421 , A61B17/0482 , A61B17/0483 , A61B17/0485 , A61B17/3468 , A61B2017/06052 , A61B2017/3433 , A61B2017/3454 , A61F2/0805
Abstract: One aspect of the present disclosure relates to a cannula for passing a tissue graft through soft tissue. The cannula can comprise an elongated body including oppositely disposed first and second ends and an axis that extends between the first and second ends. The elongated body can further include a passage extending between the first and second ends. The second end can include a curved portion that terminates at a sharpened, pointed tip configured to pierce and/or cut soft tissue at the surgical repair site. The tip can be axially offset from the axis of the elongated body at an angle that is less than 180°.
Abstract translation: 本公开的一个方面涉及一种用于使组织移植物穿过软组织的套管。 套管可以包括细长体，其包括相对设置的第一和第二端以及在第一和第二端之间延伸的轴线。 细长主体还可以包括在第一和第二端之间延伸的通道。 第二端可以包括弯曲部分，该弯曲部分终止于被设计成在手术修复部位处刺穿和/或切割软组织的尖锐尖端。 尖端可以以小于180°的角度从细长体的轴线轴向偏移。
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公开(公告)号：US20140296901A1
公开(公告)日：2014-10-02
申请号：US14212174
申请日：2014-03-14
Applicant: The Cleveland Clinic Foundation
Inventor： Kathleen A. Derwin , Joseph P. Iannotti , Ryan A. Milks
CPC classification number: A61B17/3421 , A61B17/0482 , A61B17/0483 , A61B17/0485 , A61B17/3468 , A61B2017/06052 , A61B2017/3433 , A61B2017/3454 , A61F2/0805
Abstract: One aspect of the present disclosure relates to a cannula for passing a tissue graft through soft tissue. The cannula can comprise an elongated body including oppositely disposed first and second ends and an axis that extends between the first and second ends. The elongated body can further include a passage extending between the first and second ends. The second end can include a curved portion that terminates at a sharpened, pointed tip configured to pierce and/or cut soft tissue at the surgical repair site. The tip can be axially offset from the axis of the elongated body at an angle that is less than 180°.
Abstract translation: 本公开的一个方面涉及一种用于使组织移植物穿过软组织的套管。 套管可以包括细长体，其包括相对设置的第一和第二端以及在第一和第二端之间延伸的轴线。 细长主体还可以包括在第一和第二端之间延伸的通道。 第二端可以包括弯曲部分，该弯曲部分终止于被设计成在手术修复部位处刺穿和/或切割软组织的尖锐尖端。 尖端可以以小于180°的角度从细长体的轴线轴向偏移。
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Patent Agency Ranking
公开(公告)号：US20140200440A1
公开(公告)日：2014-07-17
申请号：US14149861
申请日：2014-01-08
Applicant: THE CLEVELAND CLINIC FOUNDATION
Inventor： Joseph P. Iannotti , Wael K. Barsoum , Jason A. Bryan , Pete O'Neill
IPC: A61B5/06
CPC classification number: A61B5/061 , A61B34/20 , A61B2017/00115 , A61B2034/2065
Abstract: A method for aligning a manipulable sensor assembly includes determination of a replica surface, which represents a field of view of a manipulable sensor assembly associated with an object when the object is located in a desired position and oriented at a desired orientation. Electromagnetic radiation and/or sound reflected from a surface of the region of interest is detected to provide a surface map of the region of interest, which is compared to the replica surface to determine a rotation and/or a translation for the manipulable sensor assembly to bring the surface map into alignment with the replica surface. The position and/or the orientation of the object are altered. The detection of reflected electromagnetic radiation or sound, comparison of the surfaces, and alteration of the position and orientation of the object are repeated until the surface map is in alignment with the replica surface.
Abstract translation: 用于对准可操纵传感器组件的方法包括确定复制表面，其表示当物体位于期望位置并且以期望取向定向时与物体相关联的可操纵传感器组件的视场。 检测从感兴趣区域的表面反射的电磁辐射和/或声音以提供感兴趣区域的表面图，其与复制表面进行比较，以确定可操纵传感器组件的旋转和/或平移 使表面图与复制表面对齐。 对象的位置和/或方位被改变。 重复反射的电磁辐射或声音的检测，表面的比较以及物体的位置和取向的改变，直到表面图与复制表面对准。
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公开(公告)号：US11413112B2
公开(公告)日：2022-08-16
申请号：US16160229
申请日：2018-10-15
Applicant: VISCUS BIOLOGICS, LLC , THE CLEVELAND CLINIC FOUNDATION
Inventor： Justin Jeffrey Baker , Peter Hayes Gingras , Robert Priest , Kathe Derwin , Joseph P. Iannotti , Sambit Sahoo , Andrew Ryan Baker
IPC: A61B90/00
Abstract: A fiber-based radiopaque tissue marker for radiographic marking of tissue is provided. The marker is a sterile, single-patient-use polymeric fiber with a radiopaque material and a dye. The marker is radiopaque using standard radiographs such as x-rays and mammography. The marker can also be visualized by low-dose CT scans.
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公开(公告)号：US11213305B2
公开(公告)日：2022-01-04
申请号：US16181119
申请日：2018-11-05
Applicant: THE CLEVELAND CLINIC FOUNDATION
Inventor： Joseph P. Iannotti , Wael K. Barsoum , Jason A. Bryan , Peter D. O'Neill
Abstract: A guide for placing a landmark(s) in a patient tissue comprises a central portion defining at least one guiding bore configured to receive and guide a tool for placing the at least one landmark in the patient tissue. Extended portions project away from the central portion, each of the extended portions having respective lower base surfaces contoured to mate with the patient tissue, at least the respective lower base surfaces being customized as a function of preoperative imaging of the patient tissue, whereby the guide is specific to the patient.
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公开(公告)号：US10383657B2
公开(公告)日：2019-08-20
申请号：US14955103
申请日：2015-12-01
Applicant: THE CLEVELAND CLINIC FOUNDATION
Inventor： Kathleen A. Derwin , Joseph P. Iannotti , Ryan A. Milks
Abstract: One aspect of the present disclosure relates to a cannula for passing a tissue graft through soft tissue. The cannula can comprise an elongated body including oppositely disposed first and second ends and an axis that extends between the first and second ends. The elongated body can further include a passage extending between the first and second ends. The second end can include a curved portion that terminates at a sharpened, pointed tip configured to pierce and/or cut soft tissue at the surgical repair site. The tip can be axially offset from the axis of the elongated body at an angle that is less than 180°.
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公开(公告)号：US09741263B2
公开(公告)日：2017-08-22
申请号：US13864558
申请日：2013-04-17
Applicant: THE CLEVELAND CLINIC FOUNDATION
Inventor： Joseph P. Iannotti , Wael K. Barsoum , Jason A. Bryan , Peter D. O'Neill
IPC: A61B5/00 , G09B23/28 , A61F2/40 , A61B17/17 , G09B23/30 , G09B23/32 , G09B23/34 , A61B34/10 , A61B17/56 , A61F2/46 , A61B34/00
CPC classification number: G09B23/28 , A61B17/1739 , A61B17/1778 , A61B34/10 , A61B34/25 , A61B2017/568 , A61B2034/105 , A61B2034/108 , A61F2/4081 , A61F2002/4633 , G06F19/00 , G09B23/30 , G09B23/32 , G09B23/34
Abstract: A method for assisting a user with surgical implementation of a preoperative plan includes generating a physical native tissue model of a native patient tissue. The physical native tissue model includes at least one primary patient tissue area including a surface of interest, at least one secondary patient tissue area including no surfaces of interest, and a base surface for engaging a supporting structure. The physical native tissue model, as generated, includes at least one information feature providing clinically useful information to the user. The information feature is substantially separated from the surface of interest. An apparatus for assisting a user with surgical implementation of a preoperative plan is also provided.
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