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公开(公告)号：US09456890B2
公开(公告)日：2016-10-04
申请号：US13740365
申请日：2013-01-14
发明人： Delbert E. Day , Steven B. Jung
CPC分类号： A61F2/02 , A61F2/30965 , A61F2002/30448 , A61F2002/30766 , A61F2002/3092 , A61F2220/005 , A61L27/10 , A61L27/446 , A61L27/50 , A61L27/56 , A61L27/60 , A61L2430/02 , A61L2430/30 , A61L2430/34 , C08L67/04 , C08L33/12
摘要： A mammalian tissue scaffold and method for making a tissue scaffold including a rigid scaffold body of biocompatible glass fibers bonded together and in special alignment to define open channels within the scaffold to allow fluid flow into and within the scaffold.
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公开(公告)号：US20170014542A1
公开(公告)日：2017-01-19
申请号：US15280240
申请日：2016-09-29
发明人： Steven B. Jung , Delbert E. Day
CPC分类号： A61L15/18 , A61F13/00008 , A61F13/00034 , A61F13/069 , A61F2013/00157 , A61F2013/00221 , A61F2013/00519 , A61F2013/00829 , A61F2013/00936 , A61K9/0014 , A61K9/06 , A61K33/16 , A61K33/22 , A61K33/26 , A61K33/30 , A61K33/32 , A61K33/34 , A61K33/38 , A61L15/42 , A61L15/425 , A61L15/44 , A61L15/64 , A61L17/00 , A61L26/0004 , A61L26/0009 , A61L26/0085 , A61L2300/10 , A61L2300/102 , A61L2300/112 , A61L2300/412 , A61L2400/12
摘要： Glass-based particles of a biocompatible material which comprises 40 to about 80 wt % borate (B2O3) intermixed into a carrier which is an ointment, cream, or surgical glue.
摘要翻译： 生物相容性材料的玻璃基颗粒，其包含40至约80重量％的硼酸盐（B 2 O 3），其混合到作为软膏，乳膏或手术胶的载体中。
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公开(公告)号：US20140037756A1
公开(公告)日：2014-02-06
申请号：US13936702
申请日：2013-07-08
发明人： Delbert E. Day , Steven B. Jung , Roger F. Brown
IPC分类号： A61K33/22
CPC分类号： A61K33/22 , A61L27/10 , A61L27/56 , C03C3/14 , C03C3/19 , C03C4/0007 , C03C11/00 , C03C13/00
摘要： A three-dimensional scaffold with interconnected pores for repair of tissue comprising a scaffold body for structural support of the tissue scaffold, where the scaffold body comprises scaffold body components bonded to each other and made from component materials comprising about 40 to about 90 wt % B2O3, and two or more other oxides, wherein the scaffold body has a porosity between about 15 and about 90 vol %.
摘要翻译： 具有用于修复组织的互连孔的三维支架，其包括用于组织支架的结构支撑的支架体，其中所述支架主体包括彼此结合并由包含约40至约90重量％B 2 O 3的组分材料制成的支架主体部件 ，以及两种或更多种其它氧化物，其中所述支架体的孔隙率为约15-约90体积％。
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公开(公告)号：US20180177920A1
公开(公告)日：2018-06-28
申请号：US15510186
申请日：2015-09-09
CPC分类号： A61L27/446 , A61K47/02 , A61L27/54 , A61L27/58 , A61L2430/32 , C03B5/193 , C03B32/00 , C03B37/005 , C03B2201/62 , C03C3/064 , C03C3/15 , C03C3/19 , C03C4/0014 , C03C14/004 , C03C2204/00 , C03C2214/04 , C03C2214/30
摘要： A biocompatible, biodegradable composite material, and method of using nanoparticles formed within the composite material for nerve repair are disclosed. The nanoparticles may not be formed until the glass degrades upon contact with a fluid in vivo or in vitro.
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公开(公告)号：US20140017320A1
公开(公告)日：2014-01-16
申请号：US14028148
申请日：2013-09-16
发明人： Steven B. Jung , Delbert E. Day
CPC分类号： A61L15/18 , A61F13/00008 , A61F13/00034 , A61F13/069 , A61F2013/00157 , A61F2013/00221 , A61F2013/00519 , A61F2013/00829 , A61F2013/00936 , A61K9/0014 , A61K9/06 , A61K33/16 , A61K33/22 , A61K33/26 , A61K33/30 , A61K33/32 , A61K33/34 , A61K33/38 , A61L15/42 , A61L15/425 , A61L15/44 , A61L15/64 , A61L17/00 , A61L26/0004 , A61L26/0009 , A61L26/0085 , A61L2300/10 , A61L2300/102 , A61L2300/112 , A61L2300/412 , A61L2400/12
摘要： A method for treating a wound, and a dressing for wound care management comprising a three-dimensional body of glass-based fibers comprising one or more glass-formers selected from the group consisting of P2O5, SiO2, and B2O3; at least about 25 wt % of the fibers have a diameter between about 200 nm and about 4000 nm, and a length:width aspect ratio of at least about 10. In another form, the glasses are in the form of particles in an ointment or cream applied to a wound. In yet other forms the glasses are employed as fibers formed into sutures for closing a wound, or as particles in a surgical glue for closing a wound.
摘要翻译： 一种治疗伤口的方法和用于伤口护理管理的敷料，其包括由选自由P 2 O 5，SiO 2和B 2 O 3组成的组中的一种或多种玻璃形成剂的三维玻璃基纤维体; 纤维的至少约25重量％具有在约200nm至约4000nm之间的直径，以及至少约10的长宽宽比。在另一种形式中，所述玻璃呈软膏或 奶油适用于伤口。 在其它形式中，玻璃被用作形成用于封闭伤口的缝合线的纤维，或者作为封闭伤口的手术胶中的颗粒。
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公开(公告)号：US20130144400A1
公开(公告)日：2013-06-06
申请号：US13740365
申请日：2013-01-14
发明人： Delbert E. Day , Steven B. Jung
IPC分类号： A61F2/02
CPC分类号： A61F2/02 , A61F2/30965 , A61F2002/30448 , A61F2002/30766 , A61F2002/3092 , A61F2220/005 , A61L27/10 , A61L27/446 , A61L27/50 , A61L27/56 , A61L27/60 , A61L2430/02 , A61L2430/30 , A61L2430/34 , C08L67/04 , C08L33/12
摘要： A mammalian tissue scaffold and method for making a tissue scaffold including a rigid scaffold body of biocompatible glass fibers bonded together and in special alignment to define open channels within the scaffold to allow fluid flow into and within the scaffold.
摘要翻译： 一种用于制造组织支架的哺乳动物组织支架和方法，所述组织支架包括结合在一起的生物相容性玻璃纤维的刚性支架体，并且特别对准以在支架内限定开放通道，以允许流体流入支架内部和内部。
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公开(公告)号：US11013836B2
公开(公告)日：2021-05-25
申请号：US15625534
申请日：2017-06-16
发明人： Chang-Soo Kim , Richard K. Brow , Delbert E. Day
IPC分类号： B32B15/04 , B32B17/06 , A61L31/14 , A61L31/02 , A61K41/00 , C03C3/14 , C03C13/04 , C03C3/16 , C03C4/00 , A61N5/06 , A61B5/00
摘要： Disclosed are biodegradable glass substrates that are useful as functional elements of solid-state devices. In particular, biodegradable glass substrates having a rapidly degradable glass and a slowly degradable glass provide a structural platform that completely dissolves following a desired operational lifetime of devices such as implanted electronic devices, implanted sensor devices, and optical fibers.
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公开(公告)号：US20170247281A1
公开(公告)日：2017-08-31
申请号：US15510201
申请日：2015-09-09
发明人： Delbert E. Day , Ali Mohammadkah
CPC分类号： A61L27/446 , A61K47/02 , A61L27/54 , A61L27/58 , A61L2430/32 , C03B5/193 , C03B32/00 , C03B37/005 , C03B2201/62 , C03C3/064 , C03C3/15 , C03C3/19 , C03C4/0014 , C03C14/004 , C03C2204/00 , C03C2214/04 , C03C2214/30
摘要： A solid state method of producing inorganic nanoparticles using glass is disclosed. The nanoparticles may not be formed until the glass is reacted with or degraded by contact with a fluid in vivo or in vitro.
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公开(公告)号：US09561250B2
公开(公告)日：2017-02-07
申请号：US13936702
申请日：2013-07-08
发明人： Delbert E. Day , Steven B. Jung , Roger F. Brown
IPC分类号： A61F2/00 , A61K33/22 , A61L27/10 , A61L27/56 , C03C3/14 , C03C3/19 , C03C4/00 , C03C11/00 , C03C13/00
CPC分类号： A61K33/22 , A61L27/10 , A61L27/56 , C03C3/14 , C03C3/19 , C03C4/0007 , C03C11/00 , C03C13/00
摘要： A three-dimensional scaffold with interconnected pores for repair of tissue comprising a scaffold body for structural support of the tissue scaffold, where the scaffold body comprises scaffold body components bonded to each other and made from component materials comprising about 40 to about 90 wt % B2O3, and two or more other oxides, wherein the scaffold body has a porosity between about 15 and about 90 vol %.
摘要翻译： 具有用于修复组织的互连孔的三维支架，其包括用于组织支架的结构支撑的支架体，其中所述支架主体包括彼此结合并由包含约40至约90重量％B 2 O 3的组分材料制成的支架主体部件 ，以及两种或更多种其它氧化物，其中所述支架体的孔隙率为约15-约90体积％。
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公开(公告)号：US10350330B2
公开(公告)日：2019-07-16
申请号：US15510201
申请日：2015-09-09
发明人： Delbert E. Day , Ali Mohammadkah
IPC分类号： C03B37/005 , C03C14/00 , C03C3/064 , C03C3/15 , C03C4/00 , A61L27/44 , C03B5/193 , C03B32/00 , A61K47/02 , A61L27/54 , A61L27/58 , C03C3/19
摘要： A solid state method of producing inorganic nanoparticles using glass is disclosed. The nanoparticles may not be formed until the glass is reacted with or degraded by contact with a fluid in vivo or in vitro.
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