公开(公告)号：US20140313310A1

公开(公告)日：2014-10-23

申请号：US13861582

申请日：2013-04-12

Applicant: The Regents Of The University Of California

Inventor： Bahram Jalali ,  Keisuke Goda ,  Kevin Kin-Man Tsia

IPC: G02B21/36

CPC classification number: G02B21/361 ,  A61B1/00009 ,  A61B1/00193 ,  A61B1/0638 ,  A61B5/0062 ,  A61B5/0066 ,  A61B5/0075 ,  A61B5/0086 ,  A61B5/7257 ,  G01B9/02004 ,  G01B9/02014 ,  G01B9/02028 ,  G01B9/02044 ,  G01B9/02091 ,  G01B11/2441 ,  G01B2290/20 ,  G01B2290/65 ,  G06K9/2036 ,  G06K2209/05 ,  H04N9/045

Abstract: An apparatus and method for ultrafast real-time optical imaging that can be used for imaging dynamic events such as microfluidics or laser surgery is provided. The apparatus and methods encode spatial information from a sample into a back reflection of a two-dimensional spectral brush that is generated with a two-dimensional disperser and a light source that is mapped in to the time domain with a temporal disperser. The temporal waveform is preferably captured by an optical detector, converted to an electrical signal that is digitized and processed to provide two dimensional and three dimensional images. The produced signals can be optically or electronically amplified. Detection may be improved with correlation matching against a database in the time domain or the spatial domain. Embodiments for endoscopy, microscopy and simultaneous imaging and laser ablation with a single fiber are illustrated.

Abstract translation: 提供了一种用于超快速实时光学成像的装置和方法，可用于成像诸如微流体或激光手术的动态事件成像。 该装置和方法将来自样本的空间信息编码成二维光谱刷的背反射，其由二维分散器和用时间分散器映射到时域的光源产生。 时间波形优选地由光学检测器捕获，转换成被数字化和处理以提供二维和三维图像的电信号。 产生的信号可以是光学或电子放大的。 可以通过与时域或空间域中的数据库的相关匹配来改进检测。 示出了用于内窥镜检查，显微镜和同时成像以及使用单纤维的激光烧蚀的实施例。

公开(公告)号：US08987649B2

公开(公告)日：2015-03-24

申请号：US13861582

申请日：2013-04-12

Applicant: The Regents of the University of California

Inventor： Bahram Jalali ,  Keisuke Goda ,  Kevin Kin-Man Tsia

IPC: H01L27/00 ,  H01L31/00 ,  G02B21/36

CPC classification number: G02B21/361 ,  A61B1/00009 ,  A61B1/00193 ,  A61B1/0638 ,  A61B5/0062 ,  A61B5/0066 ,  A61B5/0075 ,  A61B5/0086 ,  A61B5/7257 ,  G01B9/02004 ,  G01B9/02014 ,  G01B9/02028 ,  G01B9/02044 ,  G01B9/02091 ,  G01B11/2441 ,  G01B2290/20 ,  G01B2290/65 ,  G06K9/2036 ,  G06K2209/05 ,  H04N9/045

Abstract: An apparatus and method for ultrafast real-time optical imaging that can be used for imaging dynamic events such as microfluidics or laser surgery is provided. The apparatus and methods encode spatial information from a sample into a back reflection of a two-dimensional spectral brush that is generated with a two-dimensional disperser and a light source that is mapped in to the time domain with a temporal disperser. The temporal waveform is preferably captured by an optical detector, converted to an electrical signal that is digitized and processed to provide two dimensional and three dimensional images. The produced signals can be optically or electronically amplified. Detection may be improved with correlation matching against a database in the time domain or the spatial domain. Embodiments for endoscopy, microscopy and simultaneous imaging and laser ablation with a single fiber are illustrated.

Abstract translation: 提供了一种用于超快速实时光学成像的装置和方法，可用于成像诸如微流体或激光手术的动态事件成像。 该装置和方法将来自样本的空间信息编码成二维光谱刷的背反射，二维光谱刷是用二维分散器和光源以及时间分散器映射到时域而生成的。 时间波形优选地由光学检测器捕获，转换成被数字化和处理以提供二维和三维图像的电信号。 产生的信号可以是光学或电子放大的。 可以通过与时域或空间域中的数据库的相关匹配来改进检测。 示出了用于内窥镜检查，显微镜和同时成像以及使用单纤维的激光烧蚀的实施例。

公开(公告)号：US20130221102A1

公开(公告)日：2013-08-29

申请号：US13770678

申请日：2013-02-19

Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

Inventor： Bahram Jalali ,  Keisuke Goda ,  Kevin Kin-Man Tsia

IPC: G06K7/14

CPC classification number: G06K7/1439 ,  G06K7/10712 ,  G06K7/10831 ,  G06K7/14

Abstract: A barcode reading apparatus and method in which the spectrum of a probe light is first Fourier-transformed into space, directed upon a barcode, and then Fourier-transformed converting the spectrally encoded barcode pattern to a time domain waveform. In one implementation, the Fourier transformation from the spectrum domain into a spatial domain is performed by a dispersive element, while the Fourier transformation from the spectrally encoded barcode pattern to a time domain waveform is performed by group-velocity dispersion (GVD). The temporally encoded barcode pattern is detected by a photodetector, digitized by a digitizer, and analyzed by a digital signal processor. The invention is applicable to a number of fields which involve the reading of one- and two-dimensional barcodes, displacement sensing, surface measurements, measurement of width and gap, flow cytometry, reading of optical media, presense or absence detection, and other related fields.

Abstract translation: 一种条形码读取装置和方法，其中探针光的光谱首先被傅里叶变换为空间，指向条形码，然后经频谱转换成频谱编码的条形码图案到时域波形。 在一个实现中，通过色散元素执行从频域到空间域的傅立叶变换，而通过组速度色散（GVD）执行从频谱编码的条形码图案到时域波形的傅里叶变换。 时间编码的条形码图案由光电检测器检测，由数字化仪数字化，并由数字信号处理器分析。 本发明可应用于涉及读取一维和二维条形码，位移检测，表面测量，宽度和间隙测量，流式细胞术，光学介质读数，预存或不存在检测等多个领域 领域。

公开(公告)号：US09835840B2

公开(公告)日：2017-12-05

申请号：US14610851

申请日：2015-01-30

Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

Inventor： Bahram Jalali ,  Keisuke Goda ,  Kevin Kin-Man Tsia

IPC: G02B21/36 ,  A61B1/00 ,  A61B1/06 ,  A61B5/00 ,  G01B11/24 ,  G06K9/20 ,  H04N9/04 ,  G01B9/02

CPC classification number: G02B21/361 ,  A61B1/00009 ,  A61B1/00193 ,  A61B1/0638 ,  A61B5/0062 ,  A61B5/0066 ,  A61B5/0075 ,  A61B5/0086 ,  A61B5/7257 ,  G01B9/02004 ,  G01B9/02014 ,  G01B9/02028 ,  G01B9/02044 ,  G01B9/02091 ,  G01B11/2441 ,  G01B2290/20 ,  G01B2290/65 ,  G06K9/2036 ,  G06K2209/05 ,  H04N9/045

Abstract: An apparatus and method for ultrafast real-time optical imaging that can be used for imaging dynamic events such as microfluidics or laser surgery is provided. The apparatus and methods encode spatial information from a sample into a back reflection of a two-dimensional spectral brush that is generated with a two-dimensional disperser and a light source that is mapped in to the time domain with a temporal disperser. The temporal waveform is preferably captured by an optical detector, converted to an electrical signal that is digitized and processed to provide two dimensional and three dimensional images. The produced signals can be optically or electronically amplified. Detection may be improved with correlation matching against a database in the time domain or the spatial domain. Embodiments for endoscopy, microscopy and simultaneous imaging and laser ablation with a single fiber are illustrated.

公开(公告)号：US20150205090A1

公开(公告)日：2015-07-23

申请号：US14610851

申请日：2015-01-30

Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

Inventor： Bahram Jalali ,  Keisuke Goda ,  Kevin Kin-Man Tsia

IPC: G02B21/36

CPC classification number: G02B21/361 ,  A61B1/00009 ,  A61B1/00193 ,  A61B1/0638 ,  A61B5/0062 ,  A61B5/0066 ,  A61B5/0075 ,  A61B5/0086 ,  A61B5/7257 ,  G01B9/02004 ,  G01B9/02014 ,  G01B9/02028 ,  G01B9/02044 ,  G01B9/02091 ,  G01B11/2441 ,  G01B2290/20 ,  G01B2290/65 ,  G06K9/2036 ,  G06K2209/05 ,  H04N9/045

Abstract: An apparatus and method for ultrafast real-time optical imaging that can be used for imaging dynamic events such as microfluidics or laser surgery is provided. The apparatus and methods encode spatial information from a sample into a back reflection of a two-dimensional spectral brush that is generated with a two-dimensional disperser and a light source that is mapped in to the time domain with a temporal disperser. The temporal waveform is preferably captured by an optical detector, converted to an electrical signal that is digitized and processed to provide two dimensional and three dimensional images. The produced signals can be optically or electronically amplified. Detection may be improved with correlation matching against a database in the time domain or the spatial domain. Embodiments for endoscopy, microscopy and simultaneous imaging and laser ablation with a single fiber are illustrated.

Abstract translation: 提供了一种用于超快速实时光学成像的装置和方法，可用于成像诸如微流体或激光手术的动态事件成像。 该装置和方法将来自样本的空间信息编码成二维光谱刷的背反射，其由二维分散器和用时间分散器映射到时域的光源产生。 时间波形优选地由光学检测器捕获，转换成被数字化和处理以提供二维和三维图像的电信号。 产生的信号可以是光学或电子放大的。 可以通过与时域或空间域中的数据库的相关匹配来改进检测。 示出了用于内窥镜检查，显微镜和同时成像以及使用单纤维的激光烧蚀的实施例。

公开(公告)号：US08870060B2

公开(公告)日：2014-10-28

申请号：US13770678

申请日：2013-02-19

Applicant: The Regents of the University of California

Inventor： Bahram Jalali ,  Keisuke Goda ,  Kevin Kin-Man Tsia

IPC: G06F17/00 ,  G06K7/10 ,  G06K7/14

CPC classification number: G06K7/1439 ,  G06K7/10712 ,  G06K7/10831 ,  G06K7/14

Abstract: A barcode reading apparatus and method in which the spectrum of a probe light is first Fourier-transformed into space, directed upon a barcode, and then Fourier-transformed converting the spectrally encoded barcode pattern to a time domain waveform. In one implementation, the Fourier transformation from the spectrum domain into a spatial domain is performed by a dispersive element, while the Fourier transformation from the spectrally encoded barcode pattern to a time domain waveform is performed by group-velocity dispersion (GVD). The temporally encoded barcode pattern is detected by a photodetector, digitized by a digitizer, and analyzed by a digital signal processor. The invention is applicable to a number of fields which involve the reading of one- and two-dimensional barcodes, displacement sensing, surface measurements, measurement of width and gap, flow cytometry, reading of optical media, presense or absence detection, and other related fields.

Abstract translation: 一种条形码读取装置和方法，其中探针光的光谱首先被傅里叶变换为空间，指向条形码，然后经频谱转换成频谱编码的条形码图案到时域波形。 在一个实现中，通过色散元素执行从频域到空间域的傅立叶变换，而通过组速度色散（GVD）执行从频谱编码的条形码图案到时域波形的傅里叶变换。 时间编码的条形码图案由光电检测器检测，由数字化仪数字化，并由数字信号处理器分析。 本发明可应用于涉及读取一维和二维条形码，位移检测，表面测量，宽度和间隙测量，流式细胞术，光学介质读数，预存或不存在检测等多个领域 领域。