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    Parallel flow cytometer using radiofrequency multiplexing
    4.
    发明授权
    Parallel flow cytometer using radiofrequency multiplexing 有权

    公开(公告)号：US10451538B2

    公开(公告)日：2019-10-22

    申请号：US16247426

    申请日：2019-01-14

    Applicant: The Regents of the University of California

    Inventor： Bahram Jalali ,  Eric Diebold ,  Brandon Buckley

    IPC: G01N15/10 ,  G01N15/14 ,  G01N33/537 ,  G01N21/64

    Abstract: An imaging flow cytometry apparatus and method which allows registering multiple locations across a cell, and/or across multiple flow channels, in parallel using radio-frequency-tagged emission (FIRE) coupled with a parallel optical detection scheme toward increasing analysis throughput. An optical source is modulated by multiple RF frequencies to produce an optical interrogation beam having a spatially distributed beat frequency. This beam is directed to one or more focused streams of cells whose responsive fluorescence, in different frequencies, is registered in parallel by an optical detector.

    SINGLE-SHOT NETWORK ANALYZER (SINA)
    5.
    发明申请
    SINGLE-SHOT NETWORK ANALYZER (SINA) 审中-公开

    公开(公告)号：US20190219480A1

    公开(公告)日：2019-07-18

    申请号：US16225144

    申请日：2018-12-19

    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

    Inventor： Bahram Jalali ,  Cejo Lonappan ,  Asad Madni

    IPC: G01M11/00

    Abstract: Apparatus and/or method for performing single-shot network analysis of electrical, electronic and electro-optical elements (e.g., components, circuits, modules, sub-systems and/or systems) on a device, or devices, under test (DUT). A pulsed optical source is directed through a first dispersion element to an modulator, while a delayed version of the pulsed optical source is directed to the DUT (pulsed optical source converted to electrical signal if DUT has electrical input), whose electrical output is fed to the modulator whose modulated optical pulse output is stretched through a second optical dispersion element, then converted to an electrical signal and processed to provide analysis and/or display of DUT response.

    ANAMORPHIC STRETCH IMAGE COMPRESSION
    7.
    发明申请
    ANAMORPHIC STRETCH IMAGE COMPRESSION 审中-公开

    公开(公告)号：US20150373369A1

    公开(公告)日：2015-12-24

    申请号：US14749628

    申请日：2015-06-24

    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

    Inventor： Bahram Jalali ,  Mohammad H. Asghari

    IPC: H04N19/59 ,  H04N19/136 ,  H04N19/80 ,  H04N19/132

    CPC classification number: H04N19/59 ,  H04N19/132 ,  H04N19/136 ,  H04N19/80

    Abstract: A feature-selective compression method and system are described which uses a transformation causing feature-selective stretching of the image being compressed. As a result, additional samples are allocated to sharp features where they are needed, and less to coarse features where they are redundant. The method can be applied to still and video images, whether they are monochrome or color images or 3D images, and operates in open-loop fashion and does not require prior knowledge of the image. The method can be applied by itself or combined with other types of compression (i.e., JPEG, WebP) to further compress the image.

    Abstract translation: 描述了使用引起要压缩的图像的特征选择性拉伸的变换的特征选择压缩方法和系统。 因此，额外的样本被分配到需要它们的尖锐特征，而较少的粗略特征则是冗余的。 该方法可以应用于静态和视频图像，无论它们是单色还是彩色图像或3D图像，并以开环方式操作，并且不需要图像的先前知识。 该方法可以自身应用或与其他类型的压缩（即，JPEG，WebP）组合来进一步压缩图像。

    METHODS FOR OPTICAL AMPLIFIED IMAGING USING A TWO-DIMENSIONAL SPECTRAL BRUSH
    8.
    发明申请
    METHODS FOR OPTICAL AMPLIFIED IMAGING USING A TWO-DIMENSIONAL SPECTRAL BRUSH 有权
    使用二维光学刷的光学放大成像方法

    公开(公告)号：US20140313310A1

    公开(公告)日：2014-10-23

    申请号：US13861582

    申请日：2013-04-12

    Applicant: The Regents Of The University Of California

    Inventor： Bahram Jalali ,  Keisuke Goda ,  Kevin Kin-Man Tsia

    IPC: G02B21/36

    CPC classification number: G02B21/361 ,  A61B1/00009 ,  A61B1/00193 ,  A61B1/0638 ,  A61B5/0062 ,  A61B5/0066 ,  A61B5/0075 ,  A61B5/0086 ,  A61B5/7257 ,  G01B9/02004 ,  G01B9/02014 ,  G01B9/02028 ,  G01B9/02044 ,  G01B9/02091 ,  G01B11/2441 ,  G01B2290/20 ,  G01B2290/65 ,  G06K9/2036 ,  G06K2209/05 ,  H04N9/045

    Abstract: An apparatus and method for ultrafast real-time optical imaging that can be used for imaging dynamic events such as microfluidics or laser surgery is provided. The apparatus and methods encode spatial information from a sample into a back reflection of a two-dimensional spectral brush that is generated with a two-dimensional disperser and a light source that is mapped in to the time domain with a temporal disperser. The temporal waveform is preferably captured by an optical detector, converted to an electrical signal that is digitized and processed to provide two dimensional and three dimensional images. The produced signals can be optically or electronically amplified. Detection may be improved with correlation matching against a database in the time domain or the spatial domain. Embodiments for endoscopy, microscopy and simultaneous imaging and laser ablation with a single fiber are illustrated.

    Abstract translation: 提供了一种用于超快速实时光学成像的装置和方法，可用于成像诸如微流体或激光手术的动态事件成像。 该装置和方法将来自样本的空间信息编码成二维光谱刷的背反射，其由二维分散器和用时间分散器映射到时域的光源产生。 时间波形优选地由光学检测器捕获，转换成被数字化和处理以提供二维和三维图像的电信号。 产生的信号可以是光学或电子放大的。 可以通过与时域或空间域中的数据库的相关匹配来改进检测。 示出了用于内窥镜检查，显微镜和同时成像以及使用单纤维的激光烧蚀的实施例。

    Parallel Flow Cytometer Using Radiofrequency Multiplexing
    10.
    发明申请
    Parallel Flow Cytometer Using Radiofrequency Multiplexing 有权

    公开(公告)号：US20220178813A1

    公开(公告)日：2022-06-09

    申请号：US17666841

    申请日：2022-02-08

    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

    Inventor： Bahram Jalali ,  Eric D. Diebold ,  Brandon Buckley

    IPC: G01N15/14 ,  G01N33/537 ,  G01N21/64

    Abstract: An imaging flow cytometry apparatus and method which allows registering multiple locations across a cell, and/or across multiple flow channels, in parallel using radio-frequency-tagged emission (FIRE) coupled with a parallel optical detection scheme toward increasing analysis throughput. An optical source is modulated by multiple RF frequencies to produce an optical interrogation beam having a spatially distributed beat frequency. This beam is directed to one or more focused streams of cells whose responsive fluorescence, in different frequencies, is registered in parallel by an optical detector.

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