-
公开(公告)号：US20240058300A1
公开(公告)日：2024-02-22
申请号：US18260115
申请日：2022-01-06
发明人： Chandan K. SEN , Sashwati ROY , Savita KHANNA , Nandini GHOSH
IPC分类号： A61K31/355 , A61P1/16
CPC分类号： A61K31/355 , A61P1/16
摘要： This invention is directed to pharmaceutical compositions comprising tocotrienol and the use of such compositions to treat non-alcoholic steatohepatitis.
-
2.发明公开公开(公告)号：US20230218780A1
公开(公告)日：2023-07-13
申请号：US18009805
申请日：2021-06-25
CPC分类号： A61K48/0016 , C12N15/85 , A61P3/10 , A61M37/0015 , C12N2800/107
摘要： Disclosed herein are compositions and in vitro and in vivo methods for reprogramming post-natal (adult and juvenile) tissue into insulinogenic cells. These compositions and methods are useful for a variety of purposes, including the development of diabetes therapies.
-
公开(公告)号：US20230348913A1
公开(公告)日：2023-11-02
申请号：US17800680
申请日：2021-03-02
发明人： Chandan K. SEN , Subhadip GHATAK , Sashwati ROY
IPC分类号： C12N15/113 , C12N15/86 , A61P17/02
CPC分类号： C12N15/1137 , C12N15/86 , A61P17/02 , C12N2310/113 , C12N2310/3231 , C12N2740/15043 , C12N2740/15071
摘要： Compositions and methods are provided for promoting wound healing in a subject by administering a composition that enhances the expression of the protein nonselenocysteine-containing phospholipid hydroperoxide glutathione peroxidase (NPGPx) in wound-edge tissues. In accordance with one embodiment such compositions are used in conjunction with known treatments for use on chronic wounds including in diabetic patients.
-
4.发明公开公开(公告)号：US20230346995A1
公开(公告)日：2023-11-02
申请号：US17923056
申请日：2021-05-11
发明人： Chandan K. SEN , Sashwati ROY
CPC分类号： A61L2/03 , A61K33/38 , A61K33/28 , A61K31/496 , A61P31/10 , A61P31/04 , A61N1/40 , A61L2202/21
摘要： Compositions and methods are provided for treating an article that is susceptible to contamination by an antimicrobial-resistant microorganism, wherein the susceptible article is exposed to an optimized electric current or field. Methods to treat an individual in need of therapy are also provided, including for example, individuals having a bacterial, viral, fungal, or parasitic infection, or individuals having an antimicrobial-resistant microbial infection, e.g., in a wound, by applying a predetermined electric current to the individual. The methods disclosed herein can be used in conjunction with a therapeutic pharmaceutical composition comprising an antimicrobial agent such as an antifungal or antibiotic pharmaceutical.
-
公开(公告)号：US20230120162A1
公开(公告)日：2023-04-20
申请号：US17799694
申请日：2021-02-26
发明人： Chandan K. SEN , Subhadip GHATAK , Sashwati ROY
IPC分类号： A61K9/127 , C12N15/113 , A61K9/19 , A61P35/00
摘要： Compositions and methods are provided for modifying the contents of exosomes released by target cells. In one embodiment cell targeted nanoparticles are used to deliver interference RNAs to the target cells which alter the packaging of exosomes released by the target cells.
-
公开(公告)号：US20240358671A1
公开(公告)日：2024-10-31
申请号：US18687205
申请日：2022-09-07
发明人： Chandan K. SEN , Sashwati ROY , Mithun SINHA , Nandini GHOSH
IPC分类号： A61K31/343 , A61K31/164 , A61P17/02 , A61P31/04
CPC分类号： A61K31/343 , A61K31/164 , A61P17/02 , A61P31/04
摘要： Compositions and methods are disclosed for treating a skin condition in a mammal in need thereof by administering to the affected tissues a therapeutically effective amount of a composition comprising a bacterial ceramidase inhibitor and/or a ceramide.
-
公开(公告)号：US20240049816A1
公开(公告)日：2024-02-15
申请号：US18259457
申请日：2021-12-20
发明人： Chandan K. SEN , Sashwati ROY , Subhadip GHATAK , Brent TOTO
CPC分类号： A41D13/1192 , B01D39/08 , B01D39/12 , A61L2/03 , A61L2202/11 , A61L2202/14 , A61L2202/26 , B01D2239/0241 , B01D2239/0442 , B01D2239/0681
摘要： This invention is directed to a multilayered fabric that comprises an electrode bearing surface that is electrically connected to a voltage source, wherein upon application of a charge, the electrode bearing will generating an electric field to neutralize pathogens and other microorganisms coming in contact with the material.
-
公开(公告)号：US20230346994A1
公开(公告)日：2023-11-02
申请号：US17923051
申请日：2021-05-11
发明人： Chandan K. SEN , Sashwati ROY , Subhadip GHATAK , Savita KHANNA
IPC分类号： A61L2/03
CPC分类号： A61L2/03 , A61L2209/14 , A61L2202/26 , A61L2300/102
摘要： Compositions and methods are provided for preparing an article that comprises an electroceutical material that comprises a redox pair of alternating metals that generate an electric current or field when exposed to an aqueous solution. In one embodiment filtering equipment including facial masks are prepared comprising the electroceutical materials.
-
公开(公告)号：US20240335563A1
公开(公告)日：2024-10-10
申请号：US18294722
申请日：2022-08-11
CPC分类号： A61K48/0058 , A61K31/7068 , A61P3/10 , C12N9/0071 , C12N9/22 , C12N15/11 , C12N15/90 , C12Y114/11 , C12N2310/20
摘要： Disclosed herein are compositions and in vitro and in vivo methods for reducing diabetes-induced epigenetic barriers in cells to enhance the efficacy of treatments of diabetes.
-
公开(公告)号：US20230346783A1
公开(公告)日：2023-11-02
申请号：US17914587
申请日：2021-04-07
IPC分类号： A61K31/506 , A61K45/06 , A61P17/02
CPC分类号： A61K31/506 , A61K45/06 , A61P17/02
摘要： Compositions and methods are provided for reducing facial contracture and to alleviate deficits associated with thermal injury of the face, including ectropion (epithelial-ocular junction), eversion of the lip (epithelial-oral junction), and oral incompetence (drooling). In accordance with one embodiment such compositions are used in conjunction with known treatments for use on burn patients.
-
-
-
-
-
-
-
-
-
搜索结果
12 条记录 (耗时 0.017 秒)
