公开(公告)号：US20230117082A1

公开(公告)日：2023-04-20

申请号：US18067264

申请日：2022-12-16

Applicant: TOPPAN Inc.

Inventor： Yoichi MAKINO ,  Akihiro HOSHINO ,  Tomoko KUNITOMI ,  Keisuke GOTO ,  Yosuke HORIUCHI

IPC: B01L3/00 ,  G01N21/64

Abstract: An analysis apparatus including a stage, an analysis device placed on the stage and including receiving sections which accommodate a sample and a reagent for biochemical reaction, and are communicated with one another through a flow path having an inlet and an outlet, a liquid introduction section which is connected to the inlet and supplies into the flow path the sample, the reagent, and an sealing liquid for sealing each of the receiving sections, and a waste liquid storage section which is connected to the outlet and stores as waste liquid an excess of the sample and the reagent and a part of the sealing liquid supplied to the flow path, an optical system which includes an objective lens, emits excitation light to the receiving sections and allows observation of fluorescence generated in the receiving sections by the excitation light, and a control unit that controls such that the sealing liquid and the excess of the sample and the reagent form an interface in the waste liquid storage section, and that the interface is formed at a distance not less than a fluorescence-obtainable distance from a bottom of the receiving sections.

公开(公告)号：US20230251197A1

公开(公告)日：2023-08-10

申请号：US18303700

申请日：2023-04-20

Applicant: TOPPAN Inc.

Inventor： Yoichi MAKINO ,  Keisuke GOTO

IPC: G01N21/64 ,  C12Q1/68 ,  G01N33/487 ,  B01L3/00 ,  G01N21/05 ,  G01N35/08 ,  C12Q1/25

CPC classification number: G01N21/645 ,  C12Q1/68 ,  G01N33/487 ,  B01L3/502715 ,  G01N21/05 ,  G01N35/08 ,  C12Q1/25 ,  G01N21/6428 ,  B01L2300/0877 ,  G01N2021/6482 ,  B01L2300/165 ,  B01L2300/0829 ,  B01L2300/0887 ,  G01N2021/058

Abstract: A microfluidic device includes a substrate having an electromagnetic wave transmission property, a micropore array layer formed on the substrate and having microwells such that the microwells is configured to receive a target of analysis, and a light absorption layer formed over the microwells of the micropore array layer such that the light absorption layer absorbs an electromagnetic wave.

公开(公告)号：US20230201826A1

公开(公告)日：2023-06-29

申请号：US18116411

申请日：2023-03-02

Applicant: TOPPAN Inc.

Inventor： Keisuke GOTO ,  Yoichi MAKINO ,  Shinichi WADA ,  Yuichiro SHINOHARA

IPC: B01L3/00

CPC classification number: B01L3/502715 ,  B01L3/5025 ,  B01L2300/0829 ,  B01L2200/0689 ,  B01L2300/041

Abstract: A fluidic device including a substrate having a well array that includes regularly arranged wells that have a same shape and are open to a surface of the substrate, and a cover member facing the well array. The well array and the cover member are positioned to have a space therebetween, which forms a flow path through which a fluid flows, and the wells including a well A and a well B closest to the well A satisfy formula (1): 0.8≤Da/Dab