公开(公告)号：US20120078527A1

公开(公告)日：2012-03-29

申请号：US13244095

申请日：2011-09-23

Applicant: Chang-eun YOO ,  Tae-jin AHN ,  Kyu-sang LEE ,  Jeo-young SHIM ,  Ki-eun KIM ,  Myoung-soon KIM ,  Sung-woo HONG ,  Tae-han JEON ,  Jhin-gook KIM ,  Se-hoon PARK ,  In-suk SOHN ,  Sin-ho JUNG

Inventor： Chang-eun YOO ,  Tae-jin AHN ,  Kyu-sang LEE ,  Jeo-young SHIM ,  Ki-eun KIM ,  Myoung-soon KIM ,  Sung-woo HONG ,  Tae-han JEON ,  Jhin-gook KIM ,  Se-hoon PARK ,  In-suk SOHN ,  Sin-ho JUNG

IPC: G06F19/00 ,  C12Q1/68 ,  C40B30/04

CPC classification number: C12Q1/6886 ,  C12Q2600/106 ,  C12Q2600/156

Abstract: A kit and method for predicting the sensitivity of gastric cancer patient to an anti-cancer agent are disclosed.

Abstract translation: 公开了一种用于预测胃癌患者对抗癌剂敏感性的试剂盒和方法。

公开(公告)号：US20100204922A1

公开(公告)日：2010-08-12

申请号：US12623675

申请日：2009-11-23

Applicant: Tae-jin AHN ,  Kyu-sang LEE ,  Dae-soon SON ,  Kyung-hee PARK

Inventor： Tae-jin AHN ,  Kyu-sang LEE ,  Dae-soon SON ,  Kyung-hee PARK

IPC: G06F19/00 ,  G06F17/18

CPC classification number: G16B20/00

Abstract: Provided are a method and apparatus for selecting pharmacogenomic markers. The method includes calculating evaluation indexes for evaluating the degree of association between genetic markers of genes associated with at least one drug and the drug, and selecting some of the genetic markers based on the calculated evaluation indexes.

Abstract translation: 提供了用于选择药物基因组标记物的方法和装置。 该方法包括计算评估指标，以评估与至少一种药物和药物相关的基因的遗传标记之间的关联程度，以及基于所计算的评价指标来选择一些遗传标记。

公开(公告)号：US20100204057A1

公开(公告)日：2010-08-12

申请号：US12691053

申请日：2010-01-21

Applicant: Kyu-sang LEE ,  Dae-soon SON ,  Kyung-hee PARK ,  Tae-jin AHN

Inventor： Kyu-sang LEE ,  Dae-soon SON ,  Kyung-hee PARK ,  Tae-jin AHN

IPC: C40B30/04 ,  C40B40/00 ,  C40B40/06 ,  C40B50/18 ,  C40B60/14

CPC classification number: G01N21/6452 ,  G01N21/645 ,  G01N2021/6441

Abstract: Provided is a substrate that is used to produce a microarray, wherein the substrate includes; a fiducial mark disposed on the substrate, and a probe immobilization region disposed on the substrate, wherein a surface of the first fiducial mark is a hydrophobic and a probe immobilization compound is immobilized on the probe immobilization region.

Abstract translation: 提供了用于制造微阵列的基板，其中基板包括： 设置在基板上的基准标记和设置在基板上的探针固定区域，其中第一基准标记的表面是疏水性的，并且探针固定化合物固定在探针固定区域上。

公开(公告)号：US20110295858A1

公开(公告)日：2011-12-01

申请号：US13074860

申请日：2011-03-29

Applicant: Tae-jin AHN ,  Kyu-sang LEE

Inventor： Tae-jin AHN ,  Kyu-sang LEE

IPC: G06F17/30

CPC classification number: G06F17/30985 ,  G06F19/22

Abstract: A method and apparatus for searching compressed nucleic acid sequences are disclosed. In the method, a reference sequence is compared with a subject sequence to be encoded, the subject sequence is compressed, an index is created with respect to the reference sequence and the compressed subject sequence, a position corresponding to a query is searched for in the compressed subject sequence using the index, a character found at the position within the compressed sequence is converted into a sequence, and the sequence is output as the response to the query.

Abstract translation: 公开了一种用于搜索压缩的核酸序列的方法和装置。 在该方法中，将参考序列与要编码的主题序列进行比较，主题序列被压缩，相对于参考序列和压缩主题序列创建索引，在相关于查询的位置搜索与 使用该索引的压缩主题序列，将在压缩序列内的位置处找到的字符转换为序列，并且将该序列作为对该查询的响应输出。

公开(公告)号：US20100256002A1

公开(公告)日：2010-10-07

申请号：US12688938

申请日：2010-01-18

Applicant: Dae-soon SON ,  Kyu-sang LEE ,  Kyung-hee PARK ,  Tae-jin AHN ,  Jong-suk CHUNG

Inventor： Dae-soon SON ,  Kyu-sang LEE ,  Kyung-hee PARK ,  Tae-jin AHN ,  Jong-suk CHUNG

IPC: C40B30/00 ,  C40B60/12

CPC classification number: G06K9/0014 ,  G06T7/73 ,  G06T2207/30072

Abstract: In a method and apparatus for detecting positions of data spots on a microarray, images of the microarray are synthesized with a grid-pattern image to distinguish spots on the microarray and synthesized images are thereby generated, and a synthesized image is selected from the synthesized images based on statistics corresponding to light intensities of fiducial spots included in the synthesized images. Accordingly, the positions of the data spots are accurately detected from the selected synthesized image, and the data of the microarray is thereby analyzed.

Abstract translation: 在用于检测微阵列上的数据点的位置的方法和装置中，利用网格图案合成微阵列的图像，以区分微阵列上的斑点，由此产生合成图像，并从合成图像中选择合成图像 基于对应于合成图像中包含的基准点的光强度的统计量。 因此，从所选择的合成图像中准确地检测数据点的位置，从而分析微阵列的数据。

公开(公告)号：US20080166729A1

公开(公告)日：2008-07-10

申请号：US11971585

申请日：2008-01-09

Applicant: Byung-chul KIM ,  Jhin-gook KIM ,  Nam HUR ,  Kyu-sang LEE ,  Dae-soon SON ,  Kyung-hee PARK ,  Tae-jin AHN

Inventor： Byung-chul KIM ,  Jhin-gook KIM ,  Nam HUR ,  Kyu-sang LEE ,  Dae-soon SON ,  Kyung-hee PARK ,  Tae-jin AHN

IPC: C12Q1/68 ,  C40B40/06

CPC classification number: C40B40/06 ,  C12Q1/6886 ,  C12Q2600/112 ,  C12Q2600/118 ,  C12Q2600/158 ,  C40B30/04 ,  Y10S977/792

Abstract: Provided is a method of predicting risk of lung cancer recurrence in a lung cancer patient or after a patient has lung cancer treatment, the method including: obtaining a biological sample from a lung cancer patient; measuring an expression level of at least one marker gene from the biological sample, the marker gene being selected from the group consisting of marker genes of Table 1, 2 or 3, to obtain data for the expression level of the marker gene; and determining whether the expression level of the marker gene corresponds to an expression level of a recurrence group or an expression level of a non-recurrence group.

Abstract translation: 本发明提供一种预测肺癌患者的肺癌复发风险或患者进行肺癌治疗后的方法，该方法包括从肺癌患者获得生物样品; 测定来自生物样品的至少一种标记基因的表达水平，所述标记基因选自表1,2或3的标记基因，以获得标记基因表达水平的数据; 确定标记基因的表达水平是否符合复发组的表达水平或非复发组的表达水平。

公开(公告)号：US20100223399A1

公开(公告)日：2010-09-02

申请号：US12635902

申请日：2009-12-11

Applicant: Seung-hwan KIM ,  Je-soo KO ,  June-koo RHEE ,  Kyu-sang LEE ,  Chan-kyun LEE ,  Ji-hoon SUNG

Inventor： Seung-hwan KIM ,  Je-soo KO ,  June-koo RHEE ,  Kyu-sang LEE ,  Chan-kyun LEE ,  Ji-hoon SUNG

IPC: G06F15/16

CPC classification number: H04J3/0667

Abstract: A method and apparatus for processing a timestamp using signature information on a physical layer is provided. The timestamp processing terminal uses a pseudo-random binary sequence to assign signature information to a message which is to be sent to another terminal, and verifies the signature information on a physical layer. The signature information is used to identify the message as a sync message. Accordingly, it is possible to precisely process the timestamp.

Abstract translation: 提供了一种使用物理层上的签名信息处理时间戳的方法和装置。 时间戳处理终端使用伪随机二进制序列将签名信息分配给要发送到另一终端的消息，并且验证物理层上的签名信息。 签名信息用于将消息标识为同步消息。 因此，可以精确地处理时间戳。

公开(公告)号：US20100208061A1

公开(公告)日：2010-08-19

申请号：US12703843

申请日：2010-02-11

Applicant: Kyu-sang LEE ,  Carl S. BROWN ,  Kyla TEPLITZ ,  Steve GOODSON

Inventor： Kyu-sang LEE ,  Carl S. BROWN ,  Kyla TEPLITZ ,  Steve GOODSON

IPC: H04N7/18 ,  G06K9/00

CPC classification number: G01N21/6452 ,  G01N21/6456 ,  G01N21/6486 ,  G06T7/75 ,  G06T2207/10056 ,  G06T2207/30024 ,  G06T2207/30204

Abstract: An apparatus for scanning a biometric device includes a camera that scans the biometric device to generate images, and a computer that extracts data from the images. The computer measures three-dimensional locations of at least three different positions on a surface of the biometric device, determines one of a virtual approximation plane and a curved surface with respect to the surface of the biometric device based on the measured three-dimensional locations, determines imaging locations of two or more panels disposed on the biometric device based on the one of the virtual approximation plane and the curved surface, obtains individual images of the two or more panels by scanning the biometric device based on the determined imaging locations, and extracts overall data of the biometric device from the individual images of the two or more panels.

Abstract translation: 用于扫描生物测定装置的装置包括扫描生物测定装置以产生图像的相机以及从图像中提取数据的计算机。 计算机测量生物测定装置的表面上的至少三个不同位置的三维位置，基于测量的三维位置确定相对于生物测定装置的表面的虚拟近似平面和弯曲表面之一， 基于虚拟近似平面和曲面中的一个，确定设置在生物测定装置上的两个或更多个面板的成像位置，通过基于确定的成像位置扫描​​生物测定装置来获得两个或更多个面板的单独图像，并且提取 来自两个或更多个面板的各个图像的生物测定装置的总体数据。

公开(公告)号：US20100190651A1

公开(公告)日：2010-07-29

申请号：US12684345

申请日：2010-01-08

Applicant: Kyung-hee PARK ,  Myo-yong LEE ,  Kyu-sang LEE ,  Jong-suk CHUNG

Inventor： Kyung-hee PARK ,  Myo-yong LEE ,  Kyu-sang LEE ,  Jong-suk CHUNG

IPC: C40B30/00

CPC classification number: C12Q1/6837 ,  C12Q2545/101

Abstract: Provided are a method of analyzing a sequence of a first probe nucleic acid using a substrate on which a second probe nucleic acid is immobilized, and a microarray and a kit for the same.

Abstract translation: 提供了使用其上固定有第二探针核酸的底物和微阵列及其用于分析第一探针核酸的试剂盒的方法来分析第一探针核酸的序列。

公开(公告)号：US20100210475A1

公开(公告)日：2010-08-19

申请号：US12704163

申请日：2010-02-11

Applicant: Kyu-sang LEE ,  Seong-ho CHO ,  Carl S. BROWN ,  Kyla TEPLITZ

Inventor： Kyu-sang LEE ,  Seong-ho CHO ,  Carl S. BROWN ,  Kyla TEPLITZ

IPC: C40B30/10 ,  B32B3/10 ,  C40B40/00 ,  G03F7/20

CPC classification number: B01J19/0046 ,  B01J2219/0054 ,  B01J2219/0056 ,  B01J2219/00608 ,  B01J2219/00693 ,  Y10T428/24802

Abstract: A substrate includes; a fiducial mark disposed on the substrate, an area on the substrate on which a probe material is configured to be immobilized, the area being separated from the fiducial mark, and a probe immobilization compound disposed on the area on the substrate on which the probe material is configured to be immobilized, wherein the fiducial mark has a structure which reflects irradiated light at a greater intensity than an intensity of reflected irradiated light form the area on the substrate not corresponding to the fiducial mark.

Abstract translation: 基板包括： 设置在基板上的基准标记，基板上的被配置为固定的探针材料的区域，与基准标记分离的区域，以及设置在基板上的探针固定化合物上的探针固定化合物，探针材料 被配置为被固定，其中基准标记具有以比反射的照射光的强度更大的强度反射照射的光的结构，形成不对应于基准标记的基板上的区域。