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1.发明授权Method of manufacturing inulotriose and/or inulotetrose using an exo-type hydrolase capable of hydrolyzing a fructan only every 3 or 4 sugar units from a terminal fructose 失效使用可水解淀粉的外部水解产物的制备方法和方法，每个3或4个来自末端纤维的糖单元
公开(公告)号：US5122460A
公开(公告)日：1992-06-16
申请号：US734558
申请日：1991-07-23
申请人： Takao Uchiyama , Mishio Kawamura , Reiko Sashida , Makoto Ueda , Sachiko Ohba , Haruyuki Ohkishi
发明人： Takao Uchiyama , Mishio Kawamura , Reiko Sashida , Makoto Ueda , Sachiko Ohba , Haruyuki Ohkishi
CPC分类号： C12Y302/0108 , C12N9/2431 , C12P19/14 , C12R1/01 , C12R1/465 , Y10S435/822 , Y10S435/886
摘要： The present invention is directed to a method of manufacturing inulotriose and/or inulotetrose by using an exo-type hydrolase capable of hydrolyzing a fructan only every 3 or 4 sugar units from a terminal fructose thereof, so as to produce inulotriose and/or inulotetrose, and of recovering the inulotriose and/or inulotetrose. The enzyme is produced by Streptomyces sp. MCI 2423 (FERM BP-2678) and Aureobacterium sp. MCI 2494 (FERM BP-2679).
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2.发明授权Exo-type hydrolase capable of hydrolyzing a fructan only every 3 or 4 sugar units 失效水解胶原蛋白的外型水解酶只能每3个或4个糖单位
公开(公告)号：US5089402A
公开(公告)日：1992-02-18
申请号：US484243
申请日：1990-02-26
申请人： Takao Uchiyama , Mishio Kawamura , Reiko Sashida , Makoto Ueda , Sachiko Ohba , Haruyuki Ohkishi
发明人： Takao Uchiyama , Mishio Kawamura , Reiko Sashida , Makoto Ueda , Sachiko Ohba , Haruyuki Ohkishi
CPC分类号： C12Y302/0108 , C12N9/2431 , C12P19/14 , C12R1/01 , C12R1/465 , Y10S435/822 , Y10S435/886
摘要： The present invention is directed to an exo-type hydrolase capable of hydrolyzing a fructan only every 3 or 4 sugar units from a terminal fructose thereof to produce predominantly inulotriose and/or inulotetrose. The enzyme is produced by Streptomyces sp. MCI 2423 (FERM BP-2678) and Aureobacterium sp. MCI 2494 (FERM BP-2679).
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3.发明授权
公开(公告)号：US4933180A
公开(公告)日：1990-06-12
申请号：US151611
申请日：1988-02-02
申请人： Takashi Mikawa , Noriko Takahashi , Haruyuki Ohkishi , Yoshikazu Sato , Shinji Miyadoh , Masaji Sezaki
发明人： Takashi Mikawa , Noriko Takahashi , Haruyuki Ohkishi , Yoshikazu Sato , Shinji Miyadoh , Masaji Sezaki
CPC分类号： C12P1/02
摘要： This disclosure describes a novel antibiotic designated Vermisporin produced in a microbiological fermentation using, for example, a new strain of Ophiobolus Vermisporus L-8. This novel antibiotic is an active antibacterial, especially anti-anaerobic bacterial agent.
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4.发明授权
公开(公告)号：US5436145A
公开(公告)日：1995-07-25
申请号：US246570
申请日：1994-05-20
CPC分类号： C12P17/12 , Y10S435/822 , Y10S435/824 , Y10S435/84 , Y10S435/843 , Y10S435/847 , Y10S435/85 , Y10S435/859 , Y10S435/874 , Y10S435/876 , Y10S435/877 , Y10S435/88 , Y10S435/881
摘要： 6-Hydroxy nitrogen-containing 6-membered ring compounds of the following general formula (II): ##STR1## wherein R.sup.1 represents carboxy group, carbamoyl group, cyano group, formyl group, C.sub.1 -C.sub.5 hydroxyalkyl group, C.sub.2 -C.sub.6 alkoxycarbonyl group, carboxyvinyl group, carboxymethyl group or oxime group, R.sup.2 represents hydrogen atom or carboxy group, and A represents carbon atom or nitrogen atom, can be prepared by reacting a nitrogen-containing 6-membered ring compounds of the following general formula (I): ##STR2## wherein R.sup.1, R.sup.2 and A are as defined in the general formula (II) above, with a microorganism or physico-chemically treated microorganism in an aqueous medium. Efficiency of the above reaction can be raised by conducting the reaction in the presence of phenazine methosulfate.
摘要翻译： 下述通式（II）的6-羟基含氮6元环化合物：其中R 1表示羧基，氨基甲酰基，氰基，甲酰基，C 1 -C 5羟基烷基，C 2 -C 6 烷氧基羰基，羧基乙烯基，羧甲基或肟基，R2表示氢原子或羧基，A表示碳原子或氮原子，可以通过使下述通式（I）的含氮6元环化合物 ）：其中R 1，R 2和A如上述通式（II）中所定义，其在水性介质中与微生物或物理化学处理的微生物一起使用。 可以通过在吩嗪甲硫酸盐存在下进行反应来提高上述反应的效率。
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公开(公告)号：US5219754A
公开(公告)日：1993-06-15
申请号：US374986
申请日：1989-07-03
申请人： Takashi Mikawa , Noriko Takahashi , Haruyuki Ohkishi , Yoshikazu Sato , Shinji Miyadoh , Masaji Sezaki
发明人： Takashi Mikawa , Noriko Takahashi , Haruyuki Ohkishi , Yoshikazu Sato , Shinji Miyadoh , Masaji Sezaki
IPC分类号： C12P1/02
CPC分类号： C12P1/02 , Y10S435/911
摘要： This disclosure describes a novel antibiotic designated Vermisporin produced in a microbiological fermentation using, for example, a new strain of Ophiobolus Vermisporus L-8. This novel antibiotic is an active antibacterial, especially anti-anaerobic bacterial agent.
摘要翻译： 该公开内容描述了使用例如新孢子虫O-Vermisporus L-8的新菌株在微生物发酵中产生的命名为Vermisporin的新型抗生素。 这种新型抗生素是一种活性抗菌剂，特别是抗厌氧细菌剂。
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