公开(公告)号：US20120225459A1

公开(公告)日：2012-09-06

申请号：US13203573

申请日：2010-02-24

申请人： Steven Lewis Kelly

发明人： Steven Lewis Kelly

IPC分类号： C12P19/02 ,  C12N1/21 ,  C12P7/06 ,  C12N15/63 ,  C12N15/56 ,  C12N9/24

CPC分类号： C12P19/02 ,  C12N9/2402 ,  C12Y302/0108 ,  Y02E50/17

摘要： The present invention relates to a novel protein and a method for the manufacture thereof. The novel protein according to the invention is a recombinant protein with fructanase activity. The recombinant protein according to the invention is an engineered protein derived from recombinant DNA encoding for the protein. The recombinant protein may be or may comprise a fragment of a naturally occurring protein, i.e. of a naturally occurring fructanase protein.

摘要翻译： 本发明涉及一种新型蛋白质及其制造方法。 根据本发明的新型蛋白质是具有果糖酶活性的重组蛋白质。 根据本发明的重组蛋白是衍生自编码该蛋白质的重组DNA的工程蛋白。 重组蛋白可以是或可以包含天然存在的蛋白质的片段，即天然存在的果糖酸酶蛋白质的片段。

公开(公告)号：US08530215B2

公开(公告)日：2013-09-10

申请号：US13203573

申请日：2010-02-24

申请人： Steven Lewis Kelly

发明人： Steven Lewis Kelly

IPC分类号： C12N9/26

CPC分类号： C12P19/02 ,  C12N9/2402 ,  C12Y302/0108 ,  Y02E50/17

摘要： The present invention relates to a novel protein and a method for the manufacture thereof. The novel protein according to the invention is a recombinant protein with fructanase activity. The recombinant protein according to the invention is an engineered protein derived from recombinant DNA encoding for the protein. The recombinant protein may be or may comprise a fragment of a naturally occurring protein, i.e. of a naturally occurring fructanase protein.

摘要翻译： 本发明涉及一种新型蛋白质及其制造方法。 根据本发明的新型蛋白质是具有果糖酶活性的重组蛋白质。 根据本发明的重组蛋白是衍生自编码该蛋白质的重组DNA的工程蛋白。 重组蛋白可以是或可以包含天然存在的蛋白质的片段，即天然存在的果糖酸酶蛋白质的片段。

公开(公告)号：US5122460A

公开(公告)日：1992-06-16

申请号：US734558

申请日：1991-07-23

申请人： Takao Uchiyama ,  Mishio Kawamura ,  Reiko Sashida ,  Makoto Ueda ,  Sachiko Ohba ,  Haruyuki Ohkishi

发明人： Takao Uchiyama ,  Mishio Kawamura ,  Reiko Sashida ,  Makoto Ueda ,  Sachiko Ohba ,  Haruyuki Ohkishi

IPC分类号： C12N9/24 ,  C12P19/14

CPC分类号： C12Y302/0108 ,  C12N9/2431 ,  C12P19/14 ,  C12R1/01 ,  C12R1/465 ,  Y10S435/822 ,  Y10S435/886

摘要： The present invention is directed to a method of manufacturing inulotriose and/or inulotetrose by using an exo-type hydrolase capable of hydrolyzing a fructan only every 3 or 4 sugar units from a terminal fructose thereof, so as to produce inulotriose and/or inulotetrose, and of recovering the inulotriose and/or inulotetrose. The enzyme is produced by Streptomyces sp. MCI 2423 (FERM BP-2678) and Aureobacterium sp. MCI 2494 (FERM BP-2679).

公开(公告)号：US12005098B2

公开(公告)日：2024-06-11

申请号：US16461977

申请日：2017-11-23

申请人： PEPSIS LIMITED

发明人： John Hunter ,  Rosemary Waring

IPC分类号： C12Q1/40 ,  A23K10/30 ,  A23K10/38 ,  A23K20/158 ,  A23K20/189 ,  A23K20/20 ,  A23K20/24 ,  A23K50/20 ,  A61K9/14 ,  A61K31/122 ,  A61K31/19 ,  A61K31/198 ,  A61K31/20 ,  A61K31/351 ,  A61K31/352 ,  A61K31/366 ,  A61K31/7008 ,  A61K33/06 ,  A61K33/24 ,  A61K36/185 ,  A61K36/45 ,  A61K36/889 ,  A61K38/47 ,  A61K45/06 ,  C12Q1/34

CPC分类号： A61K38/47 ,  A23K10/30 ,  A23K10/38 ,  A23K20/158 ,  A23K20/189 ,  A23K20/24 ,  A23K20/30 ,  A23K50/20 ,  A61K9/14 ,  A61K31/122 ,  A61K31/19 ,  A61K31/198 ,  A61K31/20 ,  A61K31/351 ,  A61K31/352 ,  A61K31/366 ,  A61K31/7008 ,  A61K33/06 ,  A61K33/24 ,  A61K36/185 ,  A61K36/45 ,  A61K36/889 ,  A61K45/06 ,  C12Q1/34 ,  C12Q1/40 ,  C12Y302/01001 ,  C12Y302/01002 ,  C12Y302/0108 ,  A23V2250/00 ,  A23V2250/1578 ,  A23V2250/1586 ,  A23V2250/1612 ,  A23V2250/1878 ,  A23V2250/21 ,  Y02P60/87 ,  A61K33/06 ,  A61K2300/00 ,  A61K33/24 ,  A61K2300/00 ,  A61K31/352 ,  A61K2300/00 ,  A61K31/198 ,  A61K2300/00 ,  A61K31/7008 ,  A61K2300/00 ,  A61K31/122 ,  A61K2300/00 ,  A61K36/185 ,  A61K2300/00 ,  A61K36/45 ,  A61K2300/00

摘要： The present invention relates to compositions comprising: malt extract including a plurality of enzymatically active enzymes including at least fructanase and amylase; one or more medium-chain triglycerides (MCTs) and/or at least one biologically acceptable metal component and use of those compositions as veterinary and human medicaments.

公开(公告)号：US20230332124A1

公开(公告)日：2023-10-19

申请号：US18042251

申请日：2021-08-23

申请人： Novozymes A/S

发明人： Dorotea Raventos Segura ,  Lorena González Palmén ,  Jesper Salomon ,  Mark Dominique Morant ,  Mette Rose Joergensen ,  Thomas Thomasen Durhuus ,  Manish Kumar Tiwari

IPC分类号： C12N9/24 ,  A61Q11/00 ,  A61K8/66 ,  A61Q11/02

CPC分类号： C12N9/2402 ,  A61Q11/00 ,  A61K8/66 ,  A61Q11/02 ,  C12Y301/21001 ,  C12Y302/01007 ,  C12Y302/01064 ,  C12Y302/01065 ,  C12Y302/0108 ,  C12Y302/01153 ,  C12Y302/01154

摘要： The present invention relates to an oral care composition comprising a fructanase, use of said composition as medicaments, use of said composition in treatment of oral disease, methods of treatment comprising administering said composition to a human or animal subject, methods of removing biofilm comprising contacting the biofilm with said composition, kits of parts comprising said composition, and fructanases.

公开(公告)号：US5089402A

公开(公告)日：1992-02-18

申请号：US484243

申请日：1990-02-26

申请人： Takao Uchiyama ,  Mishio Kawamura ,  Reiko Sashida ,  Makoto Ueda ,  Sachiko Ohba ,  Haruyuki Ohkishi

发明人： Takao Uchiyama ,  Mishio Kawamura ,  Reiko Sashida ,  Makoto Ueda ,  Sachiko Ohba ,  Haruyuki Ohkishi

IPC分类号： C12N9/24 ,  C12P19/14

CPC分类号： C12Y302/0108 ,  C12N9/2431 ,  C12P19/14 ,  C12R1/01 ,  C12R1/465 ,  Y10S435/822 ,  Y10S435/886

摘要： The present invention is directed to an exo-type hydrolase capable of hydrolyzing a fructan only every 3 or 4 sugar units from a terminal fructose thereof to produce predominantly inulotriose and/or inulotetrose. The enzyme is produced by Streptomyces sp. MCI 2423 (FERM BP-2678) and Aureobacterium sp. MCI 2494 (FERM BP-2679).

公开(公告)号：US5057418A

公开(公告)日：1991-10-15

申请号：US318255

申请日：1989-03-03

申请人： Takao Uchiyama ,  Kuniji Tanaka ,  Mishio Kawamura

发明人： Takao Uchiyama ,  Kuniji Tanaka ,  Mishio Kawamura

IPC分类号： C12N9/24 ,  C12P19/12 ,  C12P19/14 ,  C12R1/06

CPC分类号： C12Y302/0108 ,  C12N9/88 ,  C12P19/12 ,  C12P19/14 ,  C12R1/06 ,  C12Y302/01007 ,  C12Y402/02018 ,  Y10S435/83

摘要： Disclosed herein is a process for preparing difructose dianhydride III (DFA III) comprising reacting inulin with an inulin lytic enzyme derived from a microorganism belonging to Arthrobacter ilicis. The enzyme employed herein efficiently produces DFA III from inulin and is more stable against heat than conventional enzymes. The present process enables industrial continuous production of DFA III. The preferred strain used herein is Arthrobacter ilicis MCI 2297 (FERM P-9893).