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    PROPHYLACTIC OR THERAPEUTIC AGENT FOR INFLUENZA VIRUS INFECTION
    3.
    发明申请
    PROPHYLACTIC OR THERAPEUTIC AGENT FOR INFLUENZA VIRUS INFECTION 审中-公开
    用于流感病毒感染的预防或治疗药物

    公开(公告)号：US20110152178A1

    公开(公告)日：2011-06-23

    申请号：US13061370

    申请日：2009-08-07

    申请人： Toshinori Sato ,  Goshi Ishihara

    发明人： Toshinori Sato ,  Goshi Ishihara

    IPC分类号： A61K38/10 ,  C07K7/08 ,  A61P31/16

    CPC分类号： C07K7/08 ,  A61K38/00

    摘要： The present invention provides a self-assembly of a compound or of a pharmaceutically acceptable salt thereof, the compound being represented by formula (I) R1-Gly Leu Ala Met Ala Pro Ser Val Gly His Val Arg Gln His Gly-R2  (I) (wherein R1 represents a linear or branched acyl group having 14 to 24 carbon atoms; R2 represents OH, NH2, NR3R4, a substituted or unsubstituted alkoxy group, a substituted or unsubstituted aryloxy group, or a substituted or unsubstituted aralkyloxy group; and R3 and R4 independently represent a substituted or unsubstituted alkyl group, a substituted or unsubstituted aryl group, a substituted or unsubstituted aralkyl group, an alkoxy group, or a hydroxy group, provided that both R3 and R4 do not represent a hydroxy group or an alkoxy group simultaneously).

    摘要翻译： 本发明提供化合物或其药学上可接受的盐的自组装，所述化合物由式（I）表示：R1-Gly Leu Ala Met Ala Pro Ser Val Gly His Val Arg Gln His Gly-R2（I） （其中R1表示具有14-24个碳原子的直链或支链酰基; R2表示OH，NH2，NR3R4，取代或未取代的烷氧基，取代或未取代的芳氧基或取代或未取代的芳烷氧基; R3和 R4独立地表示取代或未取代的烷基，取代或未取代的芳基，取代或未取代的芳烷基，烷氧基或羟基，条件是R 3和R 4同时不表示羟基或烷氧基 ）。

    Influenza virus infection suppressor
    5.
    发明申请
    Influenza virus infection suppressor 审中-公开
    流感病毒感染抑制剂

    公开(公告)号：US20090098195A1

    公开(公告)日：2009-04-16

    申请号：US10592253

    申请日：2004-03-09

    申请人： Toshinori Sato

    发明人： Toshinori Sato

    IPC分类号： A61K9/127 ,  A61K38/00

    CPC分类号： C07K7/08 ,  A61K38/00

    摘要： The present invention is directed to providing influenza virus infection suppressors which contain a sialylgalactose-binding peptide, for example, a ganglioside GM3-binding peptide, as an active ingredient. Specifically, the invention provides influenza virus infection suppressors which contain the sialylgalactose-binding peptide of the following (a) or (b): (a) a peptide having the amino acid sequence of SEQ ID NO. 1 or 2; (b) a peptide having an amino acid sequence in which one or several nucleotides are deleted, substituted, or added, from/to the amino acid sequence of SEQ ID NO. 1 or 2, and having sialylgalactose-binding activity.

    摘要翻译： 本发明涉及提供含有唾液酸半乳糖结合肽（例如神经节苷脂GM3结合肽）作为活性成分的流感病毒感染抑制剂。 具体地，本发明提供含有下列（a）或（b）的唾液酸半乳糖结合肽的流感病毒感染抑制剂：（a）具有SEQ ID NO：1的氨基酸序列的肽。 1或2; （b）具有从SEQ ID NO：1的氨基酸序列缺失，取代或添加一个或多个核苷酸的氨基酸序列的肽。 1或2，并且具有唾液酸半乳糖结合活性。

    Sensor system and connector used therefor
    7.
    发明授权
    Sensor system and connector used therefor 有权
    传感器系统和连接器用于此

    公开(公告)号：US06945828B2

    公开(公告)日：2005-09-20

    申请号：US10754552

    申请日：2004-01-12

    申请人： Takashi Kamei ,  Kiyoshi Imai ,  Toshinori Sato ,  Kazuaki Miyoshi ,  Satoru Shimokawa

    发明人： Takashi Kamei ,  Kiyoshi Imai ,  Toshinori Sato ,  Kazuaki Miyoshi ,  Satoru Shimokawa

    IPC分类号： G01B21/00 ,  G01J3/52 ,  G01N29/24 ,  H01R9/24 ,  H01R13/514 ,  H01R31/02 ,  H03K17/94 ,  H01R9/26

    CPC分类号： H01R9/2458 ,  H03K17/94 ,  H03K2217/94094

    摘要： A sensor system includes a plurality of sensor bodies arranged aligned and adjacent to each other, each of said sensor bodies being connected to an electric cord including at least a signal line via a connector. Each connector has a power feed terminal, and a detachable fitting for electrically connecting the power feed terminals of the connectors is provided between the connectors. The power supplied to the connector of any of the sensor body through the power feed line in the electric cord is distributed to the power feed terminal of another sensor body through a row of connectors. By this configuration, the number of power feed lines for the overall system can be significantly reduced, and common bodies not distinguished for the main and sub bodies can be used as the sensor bodies, whereby the cost can be reduced and inventory management can be facilitated. Further, when any of the sensor bodies fails, it is possible to simply exchange the failed sensor body only, while maintaining the use of the electric cord that has been used.

    摘要翻译： 传感器系统包括彼此对准并相邻布置的多个传感器主体，每个所述传感器主体经由连接器至少包括信号线连接至电线。 每个连接器具有馈电端子，并且在连接器之间设置用于电连接连接器的馈电端子的可拆卸配件。 通过电线中的馈电线向传感器主体的任何一个的连接器提供的电力通过一排连接器分配到另一传感器主体的馈电端。 通过这种结构，可以显着地减少整个系统的供电线的数量，并且可以将不区分主体和副主体的共同体用作传感器体，从而可以降低成本并且可以促进库存管理 。 此外，当传感器体中的任何一个发生故障时，只要在保持使用已经使用的电线的同时简单地更换故障传感器体。

    PEPTIDE FOR INHIBITION OF INFLUENZA INFECTION, INHIBITOR OF INFLUENZA INFECTION, LIPOSOME, AND PROPHYLACTIC/THERAPEUTIC AGENT FOR INFLUENZA
    9.
    发明申请
    PEPTIDE FOR INHIBITION OF INFLUENZA INFECTION, INHIBITOR OF INFLUENZA INFECTION, LIPOSOME, AND PROPHYLACTIC/THERAPEUTIC AGENT FOR INFLUENZA 有权
    用于抑制感染感染的肽，感染感染的抑制剂，脂多糖和用于流感的预防/治疗药物

    公开(公告)号：US20100119588A1

    公开(公告)日：2010-05-13

    申请号：US12282807

    申请日：2007-03-07

    申请人： Toshinori Sato ,  Teruhiko Matsubara

    发明人： Toshinori Sato ,  Teruhiko Matsubara

    IPC分类号： A61K38/03 ,  A61K9/127 ,  C12N5/00 ,  C12N1/21 ,  C12N15/63 ,  C07K2/00 ,  C07H21/04 ,  A61P31/12

    CPC分类号： C07K14/005 ,  A61K38/00 ,  C07K5/06026 ,  C07K5/0806 ,  C07K5/1008 ,  C07K5/1024 ,  C12N2760/16122

    摘要： To provide peptides having high affinity for hemagglutinin and peptides having high inhibitory activity against influenza virus infection, as well as pharmaceutical compositions containing the peptides, the polypeptides having any one of SEQ ID NOs: 2 to 7, 9 to 10, and 12 to 18 are obtained by introducing mutation into a peptide having the sequence of ARLSPTMVHPNGAQP (peptide A-1: SEQ ID NO: 1) and screening for peptides having higher affinity for hemagglutinin. Further, the inhibitory activity of the peptide of SEQ ID NO: 3 against influenza virus infection can be enhanced by truncating SEQ ID NO: 3 in its C-terminus region with leaving ARLPR or ARLP. In addition, an influenza virus-infection inhibitor and an influenza preventive/therapeutic agent can be prepared by formulating these influenza virus receptor-binding peptides.

    摘要翻译： 为了提供对血细胞凝集素和对流感病毒感染具有高抑制活性的肽以及含有这些肽的药物组合物具有高亲和力的肽，所述多肽具有SEQ ID NO：2至7,9至10和12至18 通过将突变引入到具有ARLSPTMVHPNGAQP（肽A-1：SEQ ID NO：1）序列的肽中并筛选对血细胞凝集素具有较高亲和力的肽而获得。 此外，通过在其C末端区域截断SEQ ID NO：3，离开ARLPR或ARLP，可以增强SEQ ID NO：3的肽对流感病毒感染的抑制活性。 此外，可以通过配制这些流感病毒受体结合肽来制备流感病毒感染抑制剂和流感预防/治疗剂。

    Area monitoring multi-beam photoelectric sensor
    10.
    发明授权
    Area monitoring multi-beam photoelectric sensor 有权
    区域监控多光束光电传感器

    公开(公告)号：US07227120B2

    公开(公告)日：2007-06-05

    申请号：US11236862

    申请日：2005-09-28

    申请人： Satoru Shimokawa ,  Tetsuya Akagi ,  Takayoshi Takahara ,  Yasushi Miyake ,  Toshinori Sato ,  Shunsuke Ito

    发明人： Satoru Shimokawa ,  Tetsuya Akagi ,  Takayoshi Takahara ,  Yasushi Miyake ,  Toshinori Sato ,  Shunsuke Ito

    IPC分类号： G01J1/44 ,  H01J40/14 ,  H03F3/08 ,  G06M7/00

    CPC分类号： G01V8/20

    摘要： A multi-beam photoelectric sensor is disclosed which can be fabricated by selecting the length of a light projection/light-receiving columnar member and the number and pitches of optical axes in accordance with the width of a hazardous area of an object or the diameter of the minimum object to be detected. A projector string or a photo-detector string includes an optical module string having an alignment of a plurality of optical modules with an optical system for one optical axis, a light projection circuit for one optical axis and a plurality of flip-flops corresponding to one stage of a shift register, integrated with each other, and a flat cable. The flip-flops in the adjacent optical modules are connected in cascade by the adjacent module conduction wires thereby to make up a shift register. The optical modules making the optical module string are sequentially activated by the data sequentially sent by the shift register.

    摘要翻译： 公开了一种多光束光电传感器，其可以通过根据物体的危险区域的宽度选择光投射/光接收柱状部件的长度和光轴的数量和间距来制造，或者直径 要检测的最小对象。 投影仪串或光检测器串包括具有多个光学模块与一个光轴的光学系统对准的光学模块串，用于一个光轴的光投射电路和对应于一个光轴的多个触发器 移位寄存器的一个阶段，彼此集成，以及一个扁平电缆。 相邻光模块中的触发器由相邻的模块导线串联连接，从而构成移位寄存器。 使光模块串的光模块依次由移位寄存器发送的数据激活。