公开(公告)号：US5583227A

公开(公告)日：1996-12-10

申请号：US458871

申请日：1995-06-02

申请人： Takeshi Niho ,  Ichiro Yamamoto ,  Hidenori Mochizuki ,  Ikuo Kimura ,  Akihiro Imai ,  Tetsuyuki Nakase

发明人： Takeshi Niho ,  Ichiro Yamamoto ,  Hidenori Mochizuki ,  Ikuo Kimura ,  Akihiro Imai ,  Tetsuyuki Nakase

IPC分类号： C07D241/24 ,  C07D241/42 ,  C07D241/44 ,  A61K31/33

CPC分类号： C07D241/24 ,  C07D241/42 ,  C07D241/44

摘要： This invention relates to a novel compound which is useful as a drug in preventing and/or treating peptic ulcer-related diseases, to a production process thereof and to a pharmaceutical composition containing the same.Particularly, it provides a compound which has a specified substituted alkynylpyrazine nucleus or a specified substituted alkynylquinoxaline nucleus, represented by the following formula (I) ##STR1## wherein A is represented by the following formula (II) or (III) ##STR2## and R.sup.1 is represented by the following formula (IV), ##STR3## and the salts thereof, a production process thereof and a pharmaceutical composition containing the same.The inventive compound is useful as a drug in preventing and/or treating peptic ulcer-related diseases.

摘要翻译： 本发明涉及可用作预防和/或治疗消化性溃疡相关疾病的药物的新型化合物及其制备方法和含有该化合物的药物组合物。 特别地，其提供具有指定的取代的炔基吡嗪核的化合物或由下式（I）表示的特定的取代的炔基喹喔啉核，其中A由下式（II）或（III）表示： （II）＆lt; IMAGE＆gt;（III），R1由下式（Ⅳ），ⅩⅧ及其盐表示，其制备方法和含有该化合物的药物组合物。 本发明化合物可用作预防和/或治疗消化性溃疡相关疾病的药物。

公开(公告)号：US06956046B2

公开(公告)日：2005-10-18

申请号：US10478845

申请日：2002-05-17

申请人： Ichiro Yamamoto ,  Kazuyuki Matsuura ,  Kazuhiro Suzuki ,  Kazuo Kato ,  Yasushige Akada ,  Hidenori Mochizuki ,  Akihito Shimoi

发明人： Ichiro Yamamoto ,  Kazuyuki Matsuura ,  Kazuhiro Suzuki ,  Kazuo Kato ,  Yasushige Akada ,  Hidenori Mochizuki ,  Akihito Shimoi

IPC分类号： A61P29/00 ,  C07D211/48 ,  C07D401/12 ,  A61K31/44 ,  A61K31/4412

CPC分类号： C07D401/12 ,  C07D211/48

摘要： A compound represented by the following Formula (I): (wherein A represents oxygen atom or —NR3— (R3 represents hydrogen atom or lower alkyl group); R1 represents nitro group, lower alkoxycarbonyl group, carbamoyl group unsubstituted or mono- or di-substituted by lower alkyl group, unprotected or protected hydroxyl group, unprotected or protected carboxyl group, lower alkyl group substituted by unprotected or protected hydroxyl group, or tetrazolyl group; and R2 represents hydrogen atom, cyano group or lower alkylsulfonyl group, provided that when A is —NR3—, it is excluded that R1 represents unprotected or protected hydroxyl group or lower alkyl group substituted by unprotected or protected hydroxyl group) or its salt, and method for producing the compound, and a pharmaceutical composition containing the compound as active ingredient.

摘要翻译： 由下式（I）表示的化合物：其中A表示氧原子或-NR 3 - （R 3表示氢原子或低级烷基） SUP> 1表示硝基，低级烷氧基羰基，未取代的或被低级烷基单取代或未被保护或被保护的羟基，未被保护或保护的羧基，未被保护或被保护的羟基取代的低级烷基的氨基甲酰基 羟基或四唑基; R 2表示氢原子，氰基或低级烷基磺酰基，条件是当A是-NR 3 - 时，排除R 代表未被保护或保护的羟基或被未保护或被保护的羟基取代的低级烷基）或其盐，以及制备该化合物的方法，以及含有该化合物作为活性成分的药物组合物。

公开(公告)号：US5643920A

公开(公告)日：1997-07-01

申请号：US325339

申请日：1994-10-27

申请人： Hidenori Mochizuki ,  Kazuo Kato ,  Ichiro Yamamoto ,  Kiyoshi Mizuguchi

发明人： Hidenori Mochizuki ,  Kazuo Kato ,  Ichiro Yamamoto ,  Kiyoshi Mizuguchi

IPC分类号： C07D471/06 ,  A61K31/44 ,  C07D221/06 ,  C07D455/03

CPC分类号： C07D471/06

摘要： A nitrogen-containing tricyclic compound represented by formula (I): ##STR1## a salt thereof, or a solvate of said compound or said salt, wherein R represents phenyl or naphthyl group which is unsubstituted or substituted at one to five sites with a group such as a halogen atom; a straight chain or branched alkyl group containing 1 to 10 carbon atoms which is unsubstituted or substituted with one or more halogen atoms; or the like; Y represents hydrogen atom; and Z represents a group such as hydrogen atom, hydroxyl group, or the like; or Y and Z together represent a group such as hydrazono group, hydroxyimino group, or the like which is unsubstituted or substituted with a particular group; and X.sup.1 -X.sup.2 .about.C.about.X.sup.3 represents CH--N--C.dbd.C or N--C.dbd.C--N; provided that when X.sup.1 -X.sup.2 .about.C.about.X.sup.3 represents N--C.dbd.C--N, Y and Z does not together represent hydroxyimino group or oxygen atom; is capable of inhibiting the production of IgE antibody, and therefore, is useful as a prophylactic and/or therapeutic agent for allergic diseases.

摘要翻译： PCT No.PCT / JP93 / 00549 Sec。 371日期：1994年10月27日 102（e）日期1994年10月27日PCT提交1993年4月27日PCT公布。 公开号WO93 / 22313 日本公开号为1993年11月11日，由式（I）表示的含氮三环化合物：其中R 1表示未取代或取代的苯基或萘基的化合物或其盐的溶剂化物 在一至五个具有卤素原子的位置; 含有1至10个碳原子的直链或支链烷基，其未被取代或被一个或多个卤素原子取代; 或类似物; Y表示氢原子; Z表示氢原子，羟基等基团， 或Y和Z一起表示未被取代或被特定基团取代的亚氨基，羟基亚氨基等基团; X1-X2差异C差异X3表示CH-N-C = C或N-C = C-N; 条件是当X 1 -X 2差异C差异X3表示N-C = C-N时，Y和Z不一起表示羟基亚氨基或氧原子; 能够抑制IgE抗体的产生，因此可用作过敏性疾病的预防和/或治疗剂。

公开(公告)号：US5856334A

公开(公告)日：1999-01-05

申请号：US776435

申请日：1997-01-28

申请人： Hidenori Mochizuki ,  Kazuo Kato ,  Ichiro Yamamoto ,  Kiyoshi Mizuguchi

发明人： Hidenori Mochizuki ,  Kazuo Kato ,  Ichiro Yamamoto ,  Kiyoshi Mizuguchi

IPC分类号： C07D471/06 ,  A61K31/435 ,  A61K31/44 ,  C07D471/04

CPC分类号： C07D471/06

摘要： Specified imidazoquinoline derivatives represented by the formula (I): ##STR1## where Q represents an optionally substituted phenyl, pyridyl or furyl group; Y represents either a hydrogen atom or, when taken together with Z, an oxygen atom and a methylene group; Z represents a hydrogen atom, a hydroxymethyl group, a carboxymethyl group, a 2-oxo-1-pyrrolidinyl group or the following formula (III):--A--R.sup.2 (III)(where A represents an oxygen atom, a sulfur atom or the group --NH--);or salts of such derivatives inhibit the increase of eosinophils and are useful as agents for preventing and/or treating diseases that manifest the increase of eosinophils.

摘要翻译： PCT No.PCT / JP94 / 01900 Sec。 371日期1997年1月28日 102（e）日期1997年1月28日PCT 1994年11月10日PCT公布。 公开号WO96 / 04279 日期：1996年2月15日由式（I）表示的规格咪唑并喹啉衍生物：其中Q表示任选取代的苯基，吡啶基或呋喃基; Y表示氢原子，或与Z一起形成氧原子和亚甲基时; Z表示氢原子，羟甲基，羧甲基，2-氧代-1-吡咯烷基或下式（III）：-A-R2（III）（其中A表示氧原子，硫原子或 基团-NH-）; 或这些衍生物的盐抑制嗜酸性粒细胞的增加，并且可用作预防和/或治疗表现嗜酸性粒细胞增加的疾病的药剂。

公开(公告)号：US08440521B2

公开(公告)日：2013-05-14

申请号：US13067788

申请日：2011-06-27

申请人： Naomi Fukumaki ,  Eiji Hasegawa ,  Toshihiro Iizuka ,  Ichiro Yamamoto

发明人： Naomi Fukumaki ,  Eiji Hasegawa ,  Toshihiro Iizuka ,  Ichiro Yamamoto

IPC分类号： H01L21/3105

CPC分类号： H01L21/823857 ,  H01L21/823842

摘要： A method of manufacturing a semiconductor device having a p-type field effect transistor and an n-type field effect transistor includes the steps of: forming an interface insulating layer and a high-permittivity layer on a substrate in the stated order; forming a pattern of a sacrifice layer on the high-permittivity layer; forming a metal-containing film containing metal elements therein on the high-permittivity layer in a first region where the sacrifice layer is formed and a second region where no sacrifice layer is formed; introducing the metal elements into an interface between the interface insulating layer and the high-permittivity layer in the second region by conducting a heat treatment; and removing the sacrifice layer by wet etching, wherein in the removing step, the sacrifice layer is etched easily more than the high-permittivity layer. With this configuration, the semiconductor device excellent in reliability is obtained.

摘要翻译： 制造具有p型场效应晶体管和n型场效应晶体管的半导体器件的方法包括以下步骤：按照所述顺序在衬底上形成界面绝缘层和高电容率层; 在高电介质层上形成牺牲层的图案; 在形成有牺牲层的第一区域和形成牺牲层的第二区域的高介电常数层上形成含有金属元素的含金属膜; 通过进行热处理，将金属元素引入第二区域中的界面绝缘层与高电容率层之间的界面; 并且通过湿法蚀刻去除牺牲层，其中在去除步骤中，牺牲层比高介电常数层容易蚀刻。 由此，能够获得可靠性优异的半导体装置。

公开(公告)号：US08132572B2

公开(公告)日：2012-03-13

申请号：US12063357

申请日：2007-07-25

申请人： Hideyuki Kawabata ,  Koji Okamoto ,  Takashi Hoshina ,  Ryuhei Nagata ,  Yasuaki Nakatani ,  Terumi Shibano ,  Tomoaki Takada ,  Ryouji Kitamura ,  Toshiki Yajima ,  Daisuke Mouri ,  Kazuya Yamanaka ,  Ichiro Yamamoto ,  Shinji Katsura

发明人： Hideyuki Kawabata ,  Koji Okamoto ,  Takashi Hoshina ,  Ryuhei Nagata ,  Yasuaki Nakatani ,  Terumi Shibano ,  Tomoaki Takada ,  Ryouji Kitamura ,  Toshiki Yajima ,  Daisuke Mouri ,  Kazuya Yamanaka ,  Ichiro Yamamoto ,  Shinji Katsura

IPC分类号： A45D6/06

CPC分类号： A45D7/06 ,  A45D44/02

摘要： A permanent wave treatment apparatus comprises: a housing 3; a blower 1 which is installed within the housing to suck air and blow air; a steam separator 2 which is provided on the blower to remove water content from air sucked by suction force of the blower; an outlet hole formed in the housing through which air is spouted from the blower; hoods F mounted on the housing such that they are capable of being opened/closed freely; a plurality of rods R on which the hair of an object person is to be wound and in which air vent holes are formed; tubes 4 connected to the rods so as to keep the interior of the rods in a negative pressure by the suction force of the blower; and extraction member 5 which holds a plurality of the tubes such that they are capable of being extracted freely.

摘要翻译： 永久波处理装置包括：壳体3; 鼓风机1，其安装在壳体内以吸入空气并吹送空气; 蒸汽分离器2，其设置在鼓风机上，以通过鼓风机的吸力吸入的空气去除水分; 出口孔，形成在壳体中，空气从鼓风机喷出; 罩F安装在壳体上，使得它们能够自由地打开/关闭; 多个杆R，其上要形成有人的头发，其中形成有通气孔; 管4连接到杆上，以通过鼓风机的吸力将棒的内部保持在负压; 以及提取构件5，其保持多个管，使得它们能够自由地提取。

公开(公告)号：US20110088372A1

公开(公告)日：2011-04-21

申请号：US12906385

申请日：2010-10-18

申请人： Ichiro Yamamoto

发明人： Ichiro Yamamoto

IPC分类号： F01N11/00 ,  F01N3/10 ,  F01N9/00

CPC分类号： B01D53/9431 ,  B01D53/9495 ,  F01N3/2026 ,  F01N3/208 ,  F01N2560/026 ,  F01N2610/02 ,  F01N2900/1402 ,  F01N2900/1602 ,  F01N2900/1622 ,  Y02T10/24 ,  Y02T10/26

摘要： An exhaust gas purification apparatus for an internal combustion engine includes an exhaust passage through which exhaust gas flows, a selective catalytic reduction (SCR) catalyst provided in the exhaust passage, a urea water supply device and a control unit for controlling amount of urea water to be supplied into the exhaust passage upstream of the SCR catalyst at predetermined intervals. The control unit further estimates amount of ammonia converted from adsorbed deposit which is converted from the urea water and adsorbed on the SCR catalyst during the predetermined interval based on a physical quantity of the internal combustion engine or the exhaust gas purification apparatus, and determines amount of urea water to be supplied into the exhaust passage based on the estimated amount of ammonia converted from the adsorbed deposit on the SCR catalyst.

摘要翻译： 用于内燃机的废气净化装置包括废气流过的排气通道，设置在排气通道中的选择性催化还原（SCR）催化剂，尿素供水装置和用于控制尿素水量的控制单元 以预定的间隔供给到SCR催化剂上游的排气通路。 控制单元进一步基于内燃机或排气净化装置的物理量，估计在预定间隔内从尿素水转化并吸附在SCR催化剂上的吸附沉积物转化的氨的量， 基于从SCR催化剂上的吸附沉积物转化的氨的估计量，将供给到排气通道中的尿素水。

公开(公告)号：US07307303B2

公开(公告)日：2007-12-11

申请号：US11120995

申请日：2005-05-04

申请人： Ichiro Yamamoto

发明人： Ichiro Yamamoto

IPC分类号： H01L29/76 ,  H01L29/94

CPC分类号： H01L28/40 ,  H01L21/3142 ,  H01L21/31616 ,  H01L21/31641 ,  H01L27/10811 ,  H01L27/10814 ,  H01L27/10852

摘要： A semiconductor device is provided which has a capacitor insulating film made up of zirconium aliminate being an amorphous film obtained by having crystalline dielectric contain amorphous aluminum oxide and having its composition of AlXZr(1-X)OY (0.05≦x≦0.3), hereby being capable of preventing, in a process of forming a capacitor of MIM (Metal Insulator Metal) structure, dielectric breakdown of a capacitor insulating film while a relative dielectric constant of a metal oxide film used as the capacitor insulating film is kept high.

摘要翻译： 提供了一种半导体器件，其具有由锆合金制成的电容器绝缘膜，其是通过具有包含无定形氧化铝并且其组成为Al x Zr（1- （0.05 <= x <= 0.3），因此能够在形成MIM（金属绝缘体金属）结构的电容器的过程中防止介电击穿 电容绝缘膜，而用作电容器绝缘膜的金属氧化物膜的相对介电常数保持较高。

公开(公告)号：US20070161201A1

公开(公告)日：2007-07-12

申请号：US11531610

申请日：2006-09-13

申请人： Ichiro Yamamoto

发明人： Ichiro Yamamoto

IPC分类号： H01L21/20

CPC分类号： H01L28/40 ,  H01L21/3142 ,  H01L21/31616 ,  H01L21/31641 ,  H01L27/10811 ,  H01L27/10814 ,  H01L27/10852

摘要： A semiconductor device is provided which has a capacitor insulating film made up of zirconium aliminate being an amorphous film obtained by having crystalline dielectric contain amorphous aluminum oxide and having its composition of AlXZr(1−X)OY (0.05≦X≦0.3), hereby being capable of preventing, in a process of forming a capacitor of MIM (Metal Insulator Metal) structure, dielectric breakdown of a capacitor insulating film while a relative dielectric constant of a metal oxide film used as the capacitor insulating film is kept high.

摘要翻译： 提供了一种半导体器件，其具有由锆合金制成的电容器绝缘膜，其是通过具有包含无定形氧化铝并且其组成为Al x Zr（1- （0.05 <= X <= 0.3），因此在形成MIM（金属绝缘体金属）结构的电容器的工艺中能够防止介电击穿 电容绝缘膜，而用作电容器绝缘膜的金属氧化物膜的相对介电常数保持较高。

公开(公告)号：US07033918B2

公开(公告)日：2006-04-25

申请号：US10749915

申请日：2003-12-31

申请人： Ichiro Yamamoto ,  Naohiko Kimizuka

发明人： Ichiro Yamamoto ,  Naohiko Kimizuka

IPC分类号： H01L21/3205 ,  H01L21/4763

CPC分类号： H01L21/823842 ,  H01L21/2807

摘要： In a semiconductor device including at least one p-channel type MOS transistor, a silicon dioxide layer is formed on a silicon substrate, and a gate electrode is formed on the silicon dioxide layer. The gate electrode silicon has a three-layered structure including a silicon-seed layer formed on the silicon dioxide layer, a silicon/germanium layer formed on the silicon-seed layer, and a polycrystalline silicon layer on the silicon/germanium layer. An average grain size of polycrystalline silicon in the polycrystalline silicon layer is at most 100 nm, and p-type impurities are substantially uniformly distributed in the gate electrode along a height thereof, and the germanium atoms are diffused from the silicon/germanium layer into the silicon-seed layer at high density.

摘要翻译： 在包括至少一个p沟道型MOS晶体管的半导体器件中，在硅衬底上形成二氧化硅层，并且在二氧化硅层上形成栅电极。 栅电极硅具有三层结构，其包括在二氧化硅层上形成的硅 - 籽晶层，在硅 - 籽晶层上形成的硅/锗层和硅/锗层上的多晶硅层。 多晶硅层的多晶硅的平均晶粒尺寸为100nm以下，p型杂质沿栅极电极的高度大致均匀分布，锗原子从硅/锗层扩散到 硅籽晶层。