利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

23 条记录 (耗时 0.02 秒)

    Process for producing trans-4-hydroxy-L-proline
    2.
    发明授权
    Process for producing trans-4-hydroxy-L-proline 失效
    制备反式-4-羟基-L-脯氨酸的方法

    公开(公告)号：US5854040A

    公开(公告)日：1998-12-29

    申请号：US709874

    申请日：1996-09-09

    申请人： Akio Ozaki ,  Hideo Mori ,  Takeshi Shibasaki ,  Katsuhiko Ando ,  Shigeru Chiba

    发明人： Akio Ozaki ,  Hideo Mori ,  Takeshi Shibasaki ,  Katsuhiko Ando ,  Shigeru Chiba

    IPC分类号： C12N9/02 ,  C12P13/24

    CPC分类号： C12N9/0071 ,  C12P13/24 ,  C12Y114/11002

    摘要： Isolated and purified L-proline-4-hydroxylase which catalyzes hydroxylation of L-proline at the 4-position of L-proline in the presence of 2-ketoglutaric acid and a divalent iron ion to produce trans-4-hydroxy-L-proline. The L-proline-4-hydroxylase may be isolated from a microorganism selected from the group consisting of Dactylosporanlium sp. RHI deposited with the National Institute of Bioscience and Human-Technology Agency of Industrial Science and Technology, Japan, under the designation PERM BP-4400 and Amycolatopsis sp. RH2 deposited as FERM BP-4581.

    摘要翻译： 分离和纯化的L-脯氨酸-4-羟化酶，其在2-酮戊二酸和二价铁离子的存在下催化L-脯氨酸的4-位的L-脯氨酸的羟化作用，以产生反式-4-羟基-L-脯氨酸 。 L-脯氨酸-4-羟化酶可以从选自Dactylosporanium sp。 RHI保藏于日本工业科学与技术国家生物科学与人类技术研究所，名称为PERM BP-4400和Amycolatopsis sp。 RH2沉积为FERM BP-4581。

    Display controller
    3.
    发明授权
    Display controller 失效
    显示控制器

    公开(公告)号：US4897637A

    公开(公告)日：1990-01-30

    申请号：US33466

    申请日：1987-04-02

    申请人： Hiroshi Kobayashi ,  Takeshi Shibasaki ,  Shinji Suda

    发明人： Hiroshi Kobayashi ,  Takeshi Shibasaki ,  Shinji Suda

    IPC分类号： G06F3/153 ,  G06F3/14 ,  G09G5/22

    CPC分类号： G09G5/222

    摘要： A display controller including a first ROM, a second ROM, a RAM, and an output circuit. The first ROM stores fixed data to be displayed on a fixed data area of a display screen. The RAM stores variable data to be displayed on a variable data area of the display screen and receives controlling addresses from the first ROM. The second ROM, under control of data from a preselected one of the first ROM or the RAM, outputs the display pattern data to be displayed on the display device. The output circuit latches the display pattern data and sends it to the display device at a predetermined timing.

    摘要翻译： 一种显示控制器，包括第一ROM，第二ROM，RAM和输出电路。 第一个ROM存储要显示在显示屏的固定数据区上的固定数据。 RAM存储要显示在显示屏的可变数据区上的变量数据，并接收来自第一ROM的控制地址。 第二ROM在来自第一ROM或RAM中的预先选择的数据的数据的控制下，输出要显示在显示装置上的显示图案数据。 输出电路锁存显示图案数据，并以预定的定时将其发送到显示装置。

    Process for producing trans-4-hydroxy-L-proline
    4.
    发明申请
    Process for producing trans-4-hydroxy-L-proline 审中-公开
    制备反式-4-羟基-L-脯氨酸的方法

    公开(公告)号：US20090263885A1

    公开(公告)日：2009-10-22

    申请号：US11797687

    申请日：2007-05-07

    申请人： Akio Ozaki ,  Hideo Mori ,  Takeshi Shibasaki ,  Katsuhiko Ando ,  Shigeru Chiba

    发明人： Akio Ozaki ,  Hideo Mori ,  Takeshi Shibasaki ,  Katsuhiko Ando ,  Shigeru Chiba

    IPC分类号： C12N1/21

    CPC分类号： C12N9/0071 ,  C12P13/24 ,  C12Y114/11002

    摘要： The present invention is directed to a process for producing trans-4-hydroxy-L-proline, which is useful as a raw material for medicines or as an additive to foods. In the process, L-proline is converted into trans-4-hydroxy-L-proline in the presence of an enzyme source which is derived from a microorganism belonging to the genus Dactylosporangium, Amycolatopsis or Streptomyces and which catalyzes the hydroxylation of L-proline into trans-4-hydroxy-L-proline, a divalent iron ion and 2-ketoglutaric acid, in an aqueous medium, and the produced trans-4-hydroxy-L-proline is collected from the aqueous medium. In addition, the present invention is directed to a process for producing trans-4-hydroxy-L-proline, wherein the L-proline biosynthesis activity of the host cell of the transformant is reinforced.

    摘要翻译： 本发明涉及一种生产反式-4-羟基-L-脯氨酸的方法，其可用作药物的原料或作为食品添加剂。 在此过程中，L-脯氨酸在衍生自属于Dactylosporangium，Amycolatopsis或Streptomyces属的微生物的酶源的存在下转化成反式-4-羟基-L-脯氨酸，其催化L-脯氨酸的羟基化 在水性介质中转化成反式-4-羟基-L-脯氨酸，二价铁离子和2-酮戊二酸，从水性介质中收集生成的反式-4-羟基-L-脯氨酸。 此外，本发明涉及一种生产反式-4-羟基-L-脯氨酸的方法，其中转化体宿主细胞的L-脯氨酸生物合成活性得到增强。

    Preventive or therapeutic agents for decubitus
    5.
    发明申请
    Preventive or therapeutic agents for decubitus 审中-公开
    褥疮的预防或治疗剂

    公开(公告)号：US20080188546A1

    公开(公告)日：2008-08-07

    申请号：US12028571

    申请日：2008-02-08

    申请人： Toshiaki Takeda ,  Kenjiro Shimada ,  Hideo Kawabe ,  Takeshi Shibasaki ,  Tomoya Takahashi

    发明人： Toshiaki Takeda ,  Kenjiro Shimada ,  Hideo Kawabe ,  Takeshi Shibasaki ,  Tomoya Takahashi

    IPC分类号： A61K31/40 ,  C07D207/00 ,  A61P9/00

    CPC分类号： A61K31/401

    摘要： In accordance with the present invention, there are provided a preventive or of preventing or therapeutic agent for decubitus comprising an N-acylated derivative of hydroxyproline or a salt thereof; the above preventive or therapeutic agent wherein the N-acylated derivative of hydroxyproline or a salt thereof is contained in an amount of 0.1 to 15% by weight to the total weight; and the preventive or therapeutic agent for decubitus wherein the N-acylated group of the N-acylated derivative of hydroxyproline is an N-acylated group having 1 to 24 carbon atoms.

    摘要翻译： 根据本发明，提供了包含羟脯氨酸的N-酰化衍生物或其盐的预防或预防或治疗褥疮的治疗剂; 上述预防或治疗剂，其中羟基脯氨酸的N-酰化衍生物或其盐的含量为总重量的0.1至15重量％; 以及N-脯氨酸N-酰化衍生物的N-酰化基为碳原子数为1〜24的N-酰化基的褥疮预防或治疗剂。

    Process for producing cis-3-hydroxy-L-proline
    6.
    发明授权
    Process for producing cis-3-hydroxy-L-proline 失效
    顺式-3-羟基-L-脯氨酸的制备方法

    公开(公告)号：US5962292A

    公开(公告)日：1999-10-05

    申请号：US708856

    申请日：1996-09-09

    申请人： Akio Ozaki ,  Hideo Mori ,  Takeshi Shibasaki ,  Katsuhiko Ando ,  Keiko Ochiai ,  Shigeru Chiba ,  Yoichi Uosaki

    发明人： Akio Ozaki ,  Hideo Mori ,  Takeshi Shibasaki ,  Katsuhiko Ando ,  Keiko Ochiai ,  Shigeru Chiba ,  Yoichi Uosaki

    IPC分类号： C12N9/02 ,  C12P13/24 ,  C07H21/04 ,  C12N1/20 ,  C12N15/00

    CPC分类号： C12N9/0071 ,  C12P13/24 ,  C12Y114/11002 ,  Y10S435/814

    摘要： An industrially applicable process for producing cis-3-hydroxy-L-proline, which is useful as a raw material for medicines or as an additive to foods. In the process, L-proline is converted into cis-3-hydroxy-L-proline in the presence of an enzyme source which is derived from a microorganism belonging to the genus Streptomyces or Bacillus and which catalyzes hydroxylation of L-proline into cis-3-hydroxy-L-proline, a divalent iron ion and 2-ketoglutaric acid, in an aqueous medium, and the produced cis-3-hydroxy-L-proline is collected from the aqueous medium. A novel enzyme L-proline-3-hydroxylase, a gene of L-proline-3-hydroxylase which is useful for the process, a transformant containing the gene, and a process for producing L-proline-3-hydroxylase using the transformant.

    摘要翻译： 用于生产顺式-3-羟基-L-脯氨酸的工业上适用的方法，其可用作药物的原料或作为食品添加剂。 在此过程中，L-脯氨酸在衍生自属于链霉菌属或芽孢杆菌属的微生物的酶源存在下转化为顺式-3-羟基-L-脯氨酸，其催化L-脯氨酸的羟基化为顺式 - 3-羟基-L-脯氨酸，二价铁离子和2-酮戊二酸，在水性介质中收集生成的顺式-3-羟基-L-脯氨酸。 一种新的L-脯氨酸-3-羟化酶，可用于该方法的L-脯氨酸-3-羟化酶的基因，含该基因的转化体，以及使用转化体产生L-脯氨酸-3-羟化酶的方法。

    Screen display device
    7.
    发明授权
    Screen display device 失效
    屏幕显示设备

    公开(公告)号：US5729247A

    公开(公告)日：1998-03-17

    申请号：US572024

    申请日：1995-12-14

    申请人： Takeshi Shibasaki

    发明人： Takeshi Shibasaki

    IPC分类号： G09G1/16 ,  H04N5/445 ,  H04N7/08 ,  H04N7/081 ,  G09G5/00

    CPC分类号： G09G1/165 ,  H04N5/44504 ,  G09G2340/125

    摘要： A screen display device includes a first superimposing circuit for superimposing a first additional signal representing a first information such as characters and patterns stored in a character ROM on a composite video signal off the vertical blanking period thereof, and a second superimposing circuit for superimposing a second additional signal representing a second information such as service data stored in a data RAM or a data ROM on the composite video signal during the vertical blanking period thereof, so as to output two kinds of superimposition composite video signals to the single kind of composite video signal.

    摘要翻译： 屏幕显示装置包括：第一叠加电路，用于将代表存储在字符ROM中的字符和图案的第一信息的第一附加信号与其垂直消隐周期的复合视频信号叠加;以及第二叠加电路，用于叠加第二叠加电路 在其垂直消隐期间，代表存储在数据RAM或数据ROM中的服务数据的第二信息的附加信号，以便将两种叠加复合视频信号输出到单一复合视频信号 。

    Method for determining whether defect on disk is recess or protrusion and magnetic disk drive
    8.
    发明授权
    Method for determining whether defect on disk is recess or protrusion and magnetic disk drive 失效
    确定盘上缺陷是凹陷还是突出的方法以及磁盘驱动器

    公开(公告)号：US08705190B2

    公开(公告)日：2014-04-22

    申请号：US13604484

    申请日：2012-09-05

    申请人： Takeshi Shibasaki

    发明人： Takeshi Shibasaki

    IPC分类号： G11B27/36 ,  G11B5/02

    CPC分类号： G11B20/18 ,  G11B27/36

    摘要： According to one embodiment, there is provided a method for determining whether a defect on a disk in an apparatus includes head is a recess or a protrusion. The method detects a first defect on the disk using a read element provided in the head. The method detects a second defect on the disk using a head disk interference sensor provided in the head. The method further determines whether a third defect is a recessed defect or a protruding defect based on a ratio between a first width of the first defect in a radial direction on the disk and a second width of the second defect in the radial direction of the disk. The third defect is identified based on the first defect and the second defect.

    摘要翻译： 根据一个实施例，提供了一种用于确定包括头部的设备中的盘上的缺陷是凹陷还是突起的方法。 该方法使用设置在头部中的读取元件来检测盘上的第一缺陷。 该方法使用设置在头部中的头盘干涉传感器来检测盘上的第二缺陷。 该方法还基于盘的径向上的第一缺陷的第一宽度与盘的径向方向上的第二缺陷的第二宽度之间的比率进一步确定第三缺陷是凹陷缺陷还是突出缺陷 。 基于第一缺陷和第二缺陷来识别第三缺陷。

    MAGNETIC STORAGE APPARATUS, HEAD TEST METHOD, AND HEAD TEST APPARATUS
    9.
    发明申请
    MAGNETIC STORAGE APPARATUS, HEAD TEST METHOD, AND HEAD TEST APPARATUS 审中-公开
    磁性储存装置，头部测试方法和头部测试装置

    公开(公告)号：US20100123963A1

    公开(公告)日：2010-05-20

    申请号：US12570228

    申请日：2009-09-30

    申请人： Takeshi Shibasaki

    发明人： Takeshi Shibasaki

    IPC分类号： G11B27/36

    CPC分类号： G11B20/182 ,  G11B5/455 ,  G11B19/048 ,  G11B20/1816 ,  G11B27/36 ,  G11B2220/2516

    摘要： According to one embodiment, a magnetic storage apparatus configured to write data to and read data from a magnetic medium with a head includes a setting module, a write module, a read module, and a quality measurement module. The setting module sets a plurality of sections divided in the track direction of the magnetic medium and a predetermined reference path along the track direction, and also sets at least one offset for each of the sections such that the offset is different between adjacent sections. The offset is the position of the head with respect to the reference path. The write module writes a first data pattern to the offset set by the setting module and writes a second data pattern to the reference path a predetermined number of times. The read module reads the first data pattern written by the write module. The quality measurement module measures the quality of the first data pattern read by the read module.

    摘要翻译： 根据一个实施例，被配置为向具有磁头的磁介质写数据和从磁介质读数据的磁存储装置包括设置模块，写模块，读模块和质量测量模块。 设置模块设置在磁性介质的磁道方向上划分的多个部分和沿磁道方向的预定参考路径，并且还为每个部分设置至少一个偏移，使得相邻部分之间的偏移量不同。 偏移量是头部相对于参考路径的位置。 写入模块将第一数据模式写入由设置模块设置的偏移量，并将第二数据模式写入参考路径预定次数。 读取模块读取由写入模块写入的第一个数据模式。 质量测量模块测量读取模块读取的第一个数据模式的质量。