公开(公告)号：US20140039166A1

公开(公告)日：2014-02-06

申请号：US14005741

申请日：2012-03-15

申请人： Takuji Aimiya ,  Naoko Furusawa ,  Yasushi Nakano

发明人： Takuji Aimiya ,  Naoko Furusawa ,  Yasushi Nakano

IPC分类号： G01N21/64

CPC分类号： G01N21/6486 ,  A61K49/0093 ,  A61K49/0423 ,  B82Y5/00

摘要： A silica nanoparticle for diagnostic imaging that may be capable of use for X-ray CT, fluorescent imaging, or the like, and have high emission intensity. A method for producing such a silica nanoparticle for diagnostic imaging is provided. Also, a biosubstance labeling agent using the silica nanoparticle for diagnostic imaging is provided. The silica nanoparticle for diagnostic imaging encapsulates an organic fluorescent dye and a metal complex, wherein a ligand of the metal complex form a covalent bond with constituent molecules of the silica nanoparticle.

摘要翻译： 用于诊断成像的二氧化硅纳米颗粒，其可以用于X射线CT，荧光成像等，并且具有高发射强度。 提供了一种用于诊断成像的二氧化硅纳米粒子的制造方法。 另外，提供了使用二氧化硅纳米粒子进行诊断成像的生​​物体标记剂。 用于诊断成像的二氧化硅纳米颗粒包封有机荧光染料和金属络合物，其中金属络合物的配体与二氧化硅纳米颗粒的组成分子形成共价键。

公开(公告)号：US20130157895A1

公开(公告)日：2013-06-20

申请号：US13819574

申请日：2011-03-15

申请人： Takuji Aimiya ,  Hideki Gouda ,  Hisatake Okada ,  Yasushi Nakano ,  Kohsuke Gonda ,  Motohiro Takeda ,  Noriaki Ohuchi

发明人： Takuji Aimiya ,  Hideki Gouda ,  Hisatake Okada ,  Yasushi Nakano ,  Kohsuke Gonda ,  Motohiro Takeda ,  Noriaki Ohuchi

IPC分类号： G01N1/30 ,  G01N33/74

摘要： A tissue staining method which comprises: staining a tissue with a staining reagent wherein a biosubstance recognition site is bonded to particles carrying multiple fluorescent substances accumulated therein; in the stained tissue, counting fluorescent points or measuring fluorescent brightness; and evaluating the expression level of a biosubstance, which matches the biosubstance recognition site, in the aforesaid tissue on the basis of the number of the fluorescent points or fluorescent brightness that was measured.

公开(公告)号：US10809167B2

公开(公告)日：2020-10-20

申请号：US13819574

申请日：2011-03-15

申请人： Takuji Aimiya ,  Hideki Gouda ,  Hisatake Okada ,  Yasushi Nakano ,  Kohsuke Gonda ,  Motohiro Takeda ,  Noriaki Ohuchi

发明人： Takuji Aimiya ,  Hideki Gouda ,  Hisatake Okada ,  Yasushi Nakano ,  Kohsuke Gonda ,  Motohiro Takeda ,  Noriaki Ohuchi

IPC分类号： G01N1/30 ,  B82Y30/00 ,  B82Y15/00 ,  G01N33/58 ,  G01N21/64 ,  G01N33/74

摘要： A tissue staining method which comprises: staining a tissue with a staining reagent wherein a biosubstance recognition site is bonded to particles carrying multiple fluorescent substances accumulated therein; in the stained tissue, counting fluorescent points or measuring fluorescent brightness; and evaluating the expression level of a biosubstance, which matches the biosubstance recognition site, in the aforesaid tissue on the basis of the number of the fluorescent points or fluorescent brightness that was measured.

公开(公告)号：US20090061536A1

公开(公告)日：2009-03-05

申请号：US12162032

申请日：2007-01-23

申请人： Naoko Furusawa ,  Yasushi Nakano ,  Kazuya Tsukada

发明人： Naoko Furusawa ,  Yasushi Nakano ,  Kazuya Tsukada

IPC分类号： G01N33/536 ,  C23C16/34 ,  B32B1/00 ,  G01N21/00

CPC分类号： G01N33/588 ,  B82Y15/00 ,  B82Y30/00 ,  C01B21/068 ,  C01P2002/84 ,  C01P2004/64 ,  C01P2004/80 ,  C09K11/02 ,  C09K11/0883 ,  C09K11/59

摘要： An objective is to provide Si/Si3N4 system nanosized particles each exhibiting reduced environmental load together with minimized bio toxicity, excellent chemical stability, enhanced relative light emission intensity, and less degradation of emission intensity during continuous exposure to light; a biosubstance labeling agent capable of keeping on labeling a biosubstance exhibiting luminance enhanced for a long duration with the Si/Si3N4 system nanosized semiconductor particle of the present invention; and also a method of manufacturing the Si/Si3N4 system nanosized semiconductor particle of the present invention.

摘要翻译： 目的是提供Si / Si3N4系统的纳米尺寸颗粒，每个颗粒呈现出降低的环境负荷，同时具有最小化的生物毒性，优异的化学稳定性，增强的相对发光强度，以及在连续曝光期间较少的发射强度劣化; 能够在本发明的Si / Si 3 N 4系纳米尺寸半导体粒子上保持长时间显示亮度增加的生物体的生物物质标记剂; 以及本发明的Si / Si 3 N 4系纳米尺寸半导体粒子的制造方法。

公开(公告)号：US08658432B2

公开(公告)日：2014-02-25

申请号：US12162032

申请日：2007-01-23

申请人： Naoko Furusawa ,  Yasushi Nakano ,  Kazuya Tsukada

发明人： Naoko Furusawa ,  Yasushi Nakano ,  Kazuya Tsukada

IPC分类号： G01N33/543 ,  G01N33/552 ,  G01N21/00

CPC分类号： G01N33/588 ,  B82Y15/00 ,  B82Y30/00 ,  C01B21/068 ,  C01P2002/84 ,  C01P2004/64 ,  C01P2004/80 ,  C09K11/02 ,  C09K11/0883 ,  C09K11/59

摘要： An objective is to provide Si/Si3N4 system nanosized particles each exhibiting reduced environmental load together with minimized bio toxicity, excellent chemical stability, enhanced relative light emission intensity, and less degradation of emission intensity during continuous exposure to light; a biosubstance labeling agent capable of keeping on labeling a biosubstance exhibiting luminance enhanced for a long duration with the Si/Si3N4 system nanosized semiconductor particle of the present invention; and also a method of manufacturing the Si/Si3N4 system nanosized semiconductor particle of the present invention.

摘要翻译： 目的是提供Si / Si3N4系统的纳米尺寸颗粒，每个颗粒呈现出降低的环境负荷，同时具有最小化的生物毒性，优异的化学稳定性，增强的相对发光强度，以及在连续曝光期间较少的发射强度劣化; 能够在本发明的Si / Si 3 N 4系纳米尺寸半导体粒子上保持长时间显示亮度增加的生物体的生物物质标记剂; 以及本发明的Si / Si 3 N 4系纳米尺寸半导体粒子的制造方法。

公开(公告)号：US10163202B2

公开(公告)日：2018-12-25

申请号：US14117650

申请日：2011-05-18

申请人： Toshikazu Matsumoto ,  Yoshimi Hirasawa ,  Yasushi Nakano ,  Yusuke Wada ,  Ichiro Nakamura

发明人： Toshikazu Matsumoto ,  Yoshimi Hirasawa ,  Yasushi Nakano ,  Yusuke Wada ,  Ichiro Nakamura

IPC分类号： H04N7/18 ,  G06T7/00 ,  A61B5/15 ,  A61B5/153 ,  G01N35/00 ,  B65C3/12 ,  G06Q50/22 ,  B01L3/00 ,  A61B5/154 ,  B65C9/00

摘要： The present invention provides an automatic blood-sampling tube preparation device which can detect the presence of the proper or improper blood-sampling tube by selectively taking out a blood-sampling tube and transferring the blood-sampling tube to a label pasting position, printing information of the patient on a label, pasting the printed label on the blood-sampling tube positioned in the label pasting position, and collecting the label pasted blood-sampling tubes in the container for each patient. The device also includes photographing means for photographing an appearance of the blood-sampling tube taken out from the blood-sampling tube containing section and a control means arranged to have a threshold with respect to at least one characteristic information previously extracted from an appearance of a blood-sampling tube, to extract the characteristic information from the appearance image photographed to judge whether the blood-sampling tube corresponds to the instruction information from the doctor.

公开(公告)号：US20140015451A1

公开(公告)日：2014-01-16

申请号：US13880153

申请日：2011-10-26

申请人： Kazuhiko Funabashi ,  Nobuhiro Takano ,  Yoshikazu Kawano ,  Yasushi Nakano ,  Yuki Horie née Nitanai ,  Shinji Watanabe ,  Miyoji Onose ,  Haruhisa Fujisawa

发明人： Kazuhiko Funabashi ,  Nobuhiro Takano ,  Yoshikazu Kawano ,  Yasushi Nakano ,  Yuki Horie née Nitanai ,  Shinji Watanabe ,  Miyoji Onose ,  Haruhisa Fujisawa

IPC分类号： H02P23/00

CPC分类号： H02P23/20 ,  A01D69/02 ,  H02J7/0065 ,  H02J2007/004 ,  H02P1/028 ,  H02P27/085

摘要： A power tool system includes: a power tool including an AC motor; a portable battery pack; and a power supply device that converts a DC power supplied from the portable battery pack into an AC power to supply the AC power to the AC motor.

摘要翻译： 电动工具系统包括：电动工具，其包括交流电动机; 便携式电池组; 以及电源装置，其将从便携式电池组提供的DC电力转换为AC电力，以向AC电动机提供AC电力。

公开(公告)号：US08454857B2

公开(公告)日：2013-06-04

申请号：US12997973

申请日：2009-06-17

申请人： Kei Sakamoto ,  Yasushi Nakano

发明人： Kei Sakamoto ,  Yasushi Nakano

IPC分类号： C09K19/52 ,  C09K19/06 ,  C09K19/00 ,  C08F2/00 ,  C07C69/74

CPC分类号： C09K19/24 ,  C07C251/88 ,  C08F20/36 ,  C09K19/322 ,  C09K2019/0444 ,  C09K2019/0448 ,  G02B5/3016 ,  G02F2001/13775 ,  Y10T428/10 ,  Y10T428/1005 ,  Y10T428/1036

摘要： A polymerizable liquid crystal compound shown by the following formula, a polymerizable liquid crystal composition that includes the polymerizable liquid crystal compound and a chiral compound polymerizable with the polymerizable liquid crystal compound, a liquid crystalline polymer obtained by polymerizing the polymerizable liquid crystal compound or the polymerizable liquid crystal composition, and an optically anisotropic article that includes the liquid crystalline polymer, are disclosed. wherein Y1 to Y6 represent —O—C(═O)— or the like, G1 and G2 represent a divalent aliphatic group having 1 to 20 carbon atoms or the like, Z1 and Z2 represent an alkenyl group having 2 to 10 carbon atoms or the like, A1 and A2 represent a divalent organic group having 1 to 30 carbon atoms, M1 and M2 represent a substituted or unsubstituted 2,6-naphthylene group or a substituted or unsubstituted 1,4-phenylene group, provided that at least one of M1 and M2 represents a substituted or unsubstituted 2,6-naphthylene group, L1 and L2 represent a hydrogen atom or the like, and a and b are 0 or 1. A polymerizable liquid crystal compound that shows a liquid crystal phase over a wide temperature range, is chemically stable, can be produced inexpensively, and has a wide selective reflection wavelength band Δλ (i.e., a large value Δn); a polymerizable liquid crystal composition that includes the compound; a liquid crystalline polymer; and a optically anisotropic article that includes the liquid crystalline polymer as a constituting material; can be provided.

摘要翻译： 如下式所示的可聚合液晶化合物，包含可聚合液晶化合物的可聚合液晶组合物和可聚合液晶化合物可聚合的手性化合物，通过聚合可聚合液晶化合物或可聚合的 液晶组合物和包含液晶聚合物的光学各向异性制品。 其中Y 1至Y 6表示-OC（= O） - 等，G 1和G 2表示具有1至20个碳原子的二价脂族基等，Z 1和Z 2表示具有2至10个碳原子的烯基等 ，A1和A2表示碳原子数为1〜30的二价有机基团，M1和M2表示取代或未取代的2,6-亚萘基或取代或未取代的1,4-亚苯基，条件是M1和 M2表示取代或未取代的2,6-亚萘基，L1和L2表示氢原子等，a和b表示0或1.在宽温度范围内显示液晶相的可聚合液晶化合物， 化学稳定，可以廉价生产，并且具有宽选择性反射波长带Deltalambda（即大值Deltan）; 包含该化合物的可聚合液晶组合物; 液晶聚合物; 以及包含液晶聚合物作为构成材料的光学各向异性制品; 可以提供。

公开(公告)号：US20130051104A1

公开(公告)日：2013-02-28

申请号：US13592111

申请日：2012-08-22

申请人： Yasushi Nakano ,  Yukihiro Shima ,  Kazuhiko Funabashi ,  Nobuhiro Takano ,  Yoshikazu Kawano ,  Masayuki Ogura ,  Shinji Watanabe ,  Haruhisa Fujisawa

发明人： Yasushi Nakano ,  Yukihiro Shima ,  Kazuhiko Funabashi ,  Nobuhiro Takano ,  Yoshikazu Kawano ,  Masayuki Ogura ,  Shinji Watanabe ,  Haruhisa Fujisawa

IPC分类号： H02M7/44 ,  H02J7/04 ,  H02J7/02

CPC分类号： H02J7/0006 ,  H01M10/06 ,  H01M16/00 ,  H02H7/18 ,  H02J7/0027 ,  H02J7/045 ,  H02J7/047

摘要： A battery adapter includes an inverter device capable of converting voltage waveform from DC to AC. A first reachable battery and a second rechargeable battery different in shape can be selectively connected to the inverter device. The first rechargeable battery may, for example, a battery pack for use in an electric power tool, and the second rechargeable battery may, for example, a high-capacity lead-acid battery. With the battery adapter, two types of rechargeable batteries can be used as a power source for driving the AC-driven electric power tool. The battery adapter contains therein a microcomputer with which charge/discharge control is implemented.

摘要翻译： 电池适配器包括能够将电压波形从DC转换成AC的逆变器装置。 不同形状的第一可达电池和第二可充电电池可以选择性地连接到逆变器装置。 第一可充电电池可以是例如用于电动工具的电池组，第二可充电电池可以是例如大容量铅酸电池。 使用电池适配器，可以使用两种类型的可充电电池作为用于驱动AC驱动电动工具的电源。 电池适配器内装有执行充电/放电控制的微型计算机。

公开(公告)号：US20120101196A1

公开(公告)日：2012-04-26

申请号：US13381613

申请日：2010-06-30

申请人： Kei Sakamoto ,  Tomonori Ogawa ,  Satoshi Kiriki ,  Masanobu Shinohara ,  Yasushi Nakano

发明人： Kei Sakamoto ,  Tomonori Ogawa ,  Satoshi Kiriki ,  Masanobu Shinohara ,  Yasushi Nakano

IPC分类号： C08K5/3417 ,  C07D209/56 ,  C07D403/04 ,  C07D209/48

CPC分类号： C07D217/24 ,  C07D209/48 ,  C07D209/72 ,  C07D403/04 ,  C08K5/18 ,  C08K5/3417 ,  C08L21/00

摘要： There are provided a novel diarylamine compound represented by the following formula (I), (II) or (III), which has at least one signal attributable to the hydrogen of the N—H moiety at 8.30 ppm to 9.00 ppm when a deuterated dimethyl sulfoxide solution of the diarylamine compound is analyzed by 1H-NMR; and an aging inhibitor, a polymer composition, a crosslinked rubber product and a molded article thereof, and a method of producing a diarylamine compound. In the formulas, A1 to A6 each represent an aromatic group which may have a substituent; A represents an aromatic group or a cyclic aliphatic group, which may both have a substituent; L represents 1 or 2; and n represents 0 or 1.

摘要翻译： 提供了由下式（I），（II）或（III）表示的新型二芳基胺化合物，当氘化二甲基甲酰胺（氘代二甲基甲酰胺）为8.30ppm至9.00ppm时，其具有归属于N-H部分的氢的至少一个信号 通过1 H-NMR分析二芳基胺化合物的亚砜溶液; 和老化抑制剂，聚合物组合物，交联橡胶制品及其模制品，以及二芳基胺化合物的制备方法。 式中，A 1〜A 6表示可具有取代基的芳香族基团。 A表示可以具有取代基的芳香族基团或环状脂族基团; L表示1或2; n表示0或1。