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    Tomosynthesis imaging system and method
    1.
    发明授权
    Tomosynthesis imaging system and method 有权
    系统合成成像系统及方法

    公开(公告)号：US07356113B2

    公开(公告)日：2008-04-08

    申请号：US10776690

    申请日：2004-02-11

    申请人： Tao Wu ,  Alex Stewart ,  Martin Stanton ,  Walter Phillips ,  Daniel B. Kopans ,  Richard Moore

    发明人： Tao Wu ,  Alex Stewart ,  Martin Stanton ,  Walter Phillips ,  Daniel B. Kopans ,  Richard Moore

    IPC分类号： A61B6/02

    CPC分类号： G06T11/006 ,  A61B6/025 ,  A61B6/502 ,  A61B6/583 ,  G01N23/04 ,  G06T2211/424 ,  G06T2211/436

    摘要： A system for three-dimensional tomosynthesis imaging of a target element includes an image acquisition element and a processor. The image acquisition element obtains a plurality of images of the target element from a plurality of angles and includes a radiation source that is positionable at a plurality of angles with respect to the target element and a radiation detector. The radiation detector is positioned so as to detect radiation emitted by the radiation source passing through the target element and determine a plurality of attenuation values for radiation passing through the target element to establish a radiation absorbance projection image of the target element for a particular radiation source angle. The processor is configured to apply an iterative reconstruction algorithm to the radiation absorbance projection images of the target element obtained from a plurality of radiation source angles to generate a three-dimensional reconstruction of the target element.

    摘要翻译： 用于目标元件的三维断层合成成像的系统包括图像采集元件和处理器。 图像采集元件从多个角度获得目标元件的多个图像，并且包括可相对于目标元件以多个角度定位的辐射源和放射线检测器。 放射线检测器被定位成检测通过目标元件的辐射源发射的辐射，并确定用于通过目标元件的辐射的多个衰减值，以建立用于特定辐射源的目标元件的辐射吸收投影图像 角度。 处理器被配置为对从多个辐射源角度获得的目标元件的辐射吸收投影图像应用迭代重建算法，以产生目标元素的三维重建。

    TOMOSYNTHESIS IMAGING SYSTEM AND METHOD
    2.
    发明申请
    TOMOSYNTHESIS IMAGING SYSTEM AND METHOD 审中-公开
    TOMOSYNTHESIS成像系统和方法

    公开(公告)号：US20080232545A1

    公开(公告)日：2008-09-25

    申请号：US12099416

    申请日：2008-04-08

    申请人： Tao Wu ,  Alex Stewart ,  Martin Stanton ,  Walter Phillips ,  Daniel B. Kopans ,  Richard Moore

    发明人： Tao Wu ,  Alex Stewart ,  Martin Stanton ,  Walter Phillips ,  Daniel B. Kopans ,  Richard Moore

    IPC分类号： A61B6/00

    CPC分类号： G06T11/006 ,  A61B6/025 ,  A61B6/502 ,  A61B6/583 ,  G01N23/04 ,  G06T2211/424 ,  G06T2211/436

    摘要： A system for three-dimensional tomosynthesis imaging of a target element is provided having an image acquisition element and a processor. The image acquisition element obtains a plurality of images of the target element from a plurality of angles and includes a radiation source that is positionable at a plurality of angles with respect to the target element and a radiation detector. The radiation detector is positioned so as to detect radiation emitted by the radiation source passing through the target element and determine a plurality of attenuation values for radiation passing through the target element to establish a radiation absorbance projection image of the target element for a particular radiation source angle. The processor is configured to apply an iterative reconstruction algorithm to the radiation absorbance projection images of the target element obtained from a plurality of radiation source angles to generate a three-dimensional reconstruction of the target element. The system can gain further accuracy where the iterative reconstruction algorithm is applied using cone-beam forward projection and back projection.

    摘要翻译： 提供了具有图像采集元件和处理器的目标元件的三维断层合成成像系统。 图像采集元件从多个角度获得目标元件的多个图像，并且包括可相对于目标元件以多个角度定位的辐射源和放射线检测器。 放射线检测器被定位成检测通过目标元件的辐射源发射的辐射，并确定通过目标元件的辐射的多个衰减值，以建立用于特定辐射源的目标元件的辐射吸收投影图像 角度。 处理器被配置为对从多个辐射源角度获得的目标元件的辐射吸收投影图像应用迭代重建算法，以产生目标元素的三维重建。 在使用锥束前向投影和反投影应用迭代重建算法的情况下，系统可以获得进一步的准确性。

    Tomosynthesis imaging system and method
    3.
    发明申请
    Tomosynthesis imaging system and method 有权
    系统合成成像系统及方法

    公开(公告)号：US20050105679A1

    公开(公告)日：2005-05-19

    申请号：US10776690

    申请日：2004-02-11

    申请人： Tao Wu ,  Alex Stewart ,  Martin Stanton ,  Walter Phillips ,  Daniel Kopans ,  Richard Moore

    发明人： Tao Wu ,  Alex Stewart ,  Martin Stanton ,  Walter Phillips ,  Daniel Kopans ,  Richard Moore

    IPC分类号： A61B6/00 ,  A61B6/03 ,  G01N23/04 ,  G06T11/00 ,  G21K1/12 ,  G01N23/00 ,  H05G1/60

    CPC分类号： G06T11/006 ,  A61B6/025 ,  A61B6/502 ,  A61B6/583 ,  G01N23/04 ,  G06T2211/424 ,  G06T2211/436

    摘要： A system for three-dimensional tomosynthesis imaging of a target element is provided having an image acquisition element and a processor. The image acquisition element obtains a plurality of images of the target element from a plurality of angles and includes a radiation source that is positionable at a plurality of angles with respect to the target element and a radiation detector. The radiation detector is positioned so as to detect radiation emitted by the radiation source passing through the target element and determine a plurality of attenuation values for radiation passing through the target element to establish a radiation absorbance projection image of the target element for a particular radiation source angle. The processor is configured to apply an iterative reconstruction algorithm to the radiation absorbance projection images of the target element obtained from a plurality of radiation source angles to generate a three-dimensional reconstruction of the target element. The system can gain further accuracy where the iterative reconstruction algorithm is applied using cone-beam forward projection and back projection.

    摘要翻译： 提供了具有图像采集元件和处理器的目标元件的三维断层合成成像系统。 图像采集元件从多个角度获得目标元件的多个图像，并且包括可相对于目标元件以多个角度定位的辐射源和放射线检测器。 放射线检测器被定位成检测通过目标元件的辐射源发射的辐射，并确定用于通过目标元件的辐射的多个衰减值，以建立用于特定辐射源的目标元件的辐射吸收投影图像 角度。 处理器被配置为对从多个辐射源角度获得的目标元件的辐射吸收投影图像应用迭代重建算法，以产生目标元素的三维重建。 在使用锥束前向投影和反投影应用迭代重建算法的情况下，系统可以获得进一步的准确性。

    Ovarian Cancer Biomarkers and Uses Thereof
    6.
    发明申请
    Ovarian Cancer Biomarkers and Uses Thereof 审中-公开
    卵巢癌生物标志物及其用途

    公开(公告)号：US20100221752A2

    公开(公告)日：2010-09-02

    申请号：US12574341

    申请日：2009-10-06

    申请人： Larry Gold ,  Marty Stanton ,  Edward Brody ,  Rachel Ostroff ,  Dominic Zichi ,  Alex Stewart

    发明人： Larry Gold ,  Marty Stanton ,  Edward Brody ,  Rachel Ostroff ,  Dominic Zichi ,  Alex Stewart

    IPC分类号： G01N33/567 ,  G01N33/53 ,  G06F19/00 ,  G06F17/18

    CPC分类号： G01N33/57449 ,  G06F19/24 ,  Y10T436/143333

    摘要： The present application includes biomarkers, methods, devices, reagents, systems, and kits for the detection and diagnosis of ovarian cancer. In one aspect, the application provides biomarkers that can be used alone or in various combinations to diagnose ovarian cancer or permit the differential diagnosis of a pelvic mass as benign or malignant. In another aspect, methods are provided for diagnosing ovarian cancer in an individual, where the methods include detecting, in a biological sample from an individual, at least one biomarker value corresponding to at least one biomarker selected from the group of biomarkers provided in Table 1, wherein the individual is classified as having ovarian cancer, or the likelihood of the individual having ovarian cancer is determined, based on the at least one biomarker value.

    摘要翻译： 本申请包括用于卵巢癌的检测和诊断的生物标志物，方法，装置，试剂，系统和试剂盒。 一方面，本申请提供可以单独使用或以各种组合使用以诊断卵巢癌或允许骨盆块的鉴别诊断为良性或恶性的生物标志物。 在另一方面，提供了用于诊断个体中的卵巢癌的方法，其中所述方法包括在来自个体的生物样品中检测至少一种对应于选自表1中提供的生物标志物组的至少一种生物标志物的生物标记值 ，其中基于所述至少一种生物标志物值将所述个体分类为具有卵巢癌或确定具有卵巢癌的个体的可能性。

    Firearm Cartridge
    7.
    发明申请
    Firearm Cartridge 有权

    公开(公告)号：US20230080170A1

    公开(公告)日：2023-03-16

    申请号：US17900231

    申请日：2022-08-31

    申请人： Alex Stewart

    发明人： Alex Stewart

    IPC分类号： F42B5/02

    摘要： A firearm cartridge system is provided and includes a case with a neck portion, body portion, shoulder portion, a base portion, and a indentation. The neck portion has a diameter between about 0.249 in to about 0.256 in. The body portion tapers from a first end having a diameter between about 0.465 in to about 0.475 to a second end having a diameter between about 0.449 in to about 0.458 in. The shoulder portion connects the body portion and neck portion and has a diameter between about 0.395 in to about 0.405 in. The base portion is positioned on the second end of the body portion and has diameter between about 0.463 in to about 0.477 in. The indentation joins the body portion and the base portion and includes a sidewall with angle between 30° to 42°.

    REAL-TIME OUTPUT CORRECTION OF DETECTOR OUTPUTS RESULTING FROM AZIMUTHAL X-RAY SOURCE VARIATIONS USING MONITORING DETECTORS
    8.
    发明申请
    REAL-TIME OUTPUT CORRECTION OF DETECTOR OUTPUTS RESULTING FROM AZIMUTHAL X-RAY SOURCE VARIATIONS USING MONITORING DETECTORS 审中-公开

    公开(公告)号：US20190018166A1

    公开(公告)日：2019-01-17

    申请号：US16123511

    申请日：2018-09-06

    申请人： Philip Teague ,  Alex Stewart

    发明人： Philip Teague ,  Alex Stewart

    IPC分类号： G01V5/04 ,  G01V5/12 ,  G01V5/10

    摘要： A measurement compensation mechanism for an electronic radiation source-based borehole logging tool that compensates for geometric variations in the direction output of an x-ray source is provided, the measurement compensation system including: at least one electronic radiation source; at least one radiation shield; at least three reference detectors; and at least one borehole measuring radiation detector. A method of compensating the measurement of an electronic radiation source-based borehole logging tool that compensates for geometric variations in the direction output of an x-ray source is also provided, the method including at least: measuring an azimuthal distribution of radiation intensities equidistant from an electronic radiation source in order to correct a measured radiation value of a borehole-measuring radiation detector relative to the borehole-measuring radiation detector's azimuthal measurement direction.