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26 条记录 (耗时 0.036 秒)

    VASODILATOR
    8.
    发明申请
    VASODILATOR 审中-公开

    公开(公告)号：US20090234097A1

    公开(公告)日：2009-09-17

    申请号：US12279218

    申请日：2007-02-14

    申请人： Tatsuhiko Hirota ,  Kohji Ohki

    发明人： Tatsuhiko Hirota ,  Kohji Ohki

    IPC分类号： C07K5/08

    CPC分类号： C07K5/0808 ,  A23L33/18 ,  A23V2002/00 ,  A61K38/06 ,  A23V2200/326

    摘要： There is provided a vasodilator having an endothelium-dependent vasodilator effect, a prophylactic of arteriosclerosis, and functional food having an endothelium-dependent vasodilator effect, which is suitable for daily and regular intake and excellent in safety. The vasodilator and the functional food according to the present invention are characterized in at least one of the tripeptides Val-Pro-Pro and Ile-Pro-Pro, or a proteolytic product containing Val-Pro-Pro and/or Ile-Pro-Pro, contained as an active component.

    摘要翻译： 提供了具有内皮依赖性血管舒张作用，动脉硬化预防性和具有内皮依赖性血管扩张作用的功能性食品的血管扩张剂，其适合日常摄取和定期摄取，安全性优异。 根据本发明的血管扩张剂和功能性食品的特征在于至少一种三肽Val-Pro-Pro和Ile-Pro-Pro，或含有Val-Pro-Pro和/或Ile-Pro-Pro的蛋白水解产物 ，作为活性成分。

    RHEUMATOID ARTHRITIS-PREVENTIVE AGENT FOR ORAL INTAKE
    9.
    发明申请
    RHEUMATOID ARTHRITIS-PREVENTIVE AGENT FOR ORAL INTAKE 审中-公开
    用于口服摄入的盐酸抗炎药物预防剂

    公开(公告)号：US20100167979A1

    公开(公告)日：2010-07-01

    申请号：US12278880

    申请日：2007-02-09

    申请人： Michio Hatori ,  Kohji Ohki ,  Naomi Hashimura ,  Tatsuhiko Hirota ,  Kazuhito Ohsawa

    发明人： Michio Hatori ,  Kohji Ohki ,  Naomi Hashimura ,  Tatsuhiko Hirota ,  Kazuhito Ohsawa

    IPC分类号： A61K38/01 ,  A61P19/02

    CPC分类号： A61K38/018 ,  A23L33/175 ,  A23L33/18 ,  A23L33/19 ,  A61K31/198 ,  A61K35/20

    摘要： There is provided a rheumatoid arthritis inhibitor for oral intake that has an inhibitory effect on rheumatoid arthritis and is excellent in safety. The rheumatoid arthritis inhibitor for oral intake of the present invention contains, as an active component, a casein hydrolysate containing free amino acids and peptides obtained by hydrolyzing animal milk casein to have an average chain length of not longer than 2.1 in terms of the number of amino acid residues, or a mixture of free amino acids and peptides contained in the hydrolysate.

    摘要翻译： 提供了对类风湿性关节炎具有抑制作用的口服摄入类风湿性关节炎抑制剂，安全性优异。 本发明的口服类风湿关节炎抑制剂作为活性成分含有含有游离氨基酸的酪蛋白水解物和通过水解动物乳酪蛋白得到的肽，其平均链长度不得大于2.1 氨基酸残基或游离氨基酸和包含在水解产物中的肽的混合物。

    Skin aging-inhibiting peptide
    10.
    发明授权
    Skin aging-inhibiting peptide 有权
    皮肤老化抑制肽

    公开(公告)号：US09067972B2

    公开(公告)日：2015-06-30

    申请号：US12874610

    申请日：2010-09-02

    申请人： Kazuhito Ohsawa ,  Naoto Uchida ,  Hidehiko Baba ,  Michio Hatori ,  Kohji Ohki

    发明人： Kazuhito Ohsawa ,  Naoto Uchida ,  Hidehiko Baba ,  Michio Hatori ,  Kohji Ohki

    IPC分类号： A61K38/07 ,  C07K16/00 ,  C07K5/103 ,  C07K5/083 ,  C07K5/107 ,  C07K7/06 ,  A61K38/00

    CPC分类号： C07K5/101 ,  A61K38/00 ,  C07K5/0808 ,  C07K5/1016 ,  C07K7/06

    摘要： The present invention provides a peptide and a composition which are suitable for oral ingestion, and which have a skin aging-inhibiting activity, a collagen-production promoting activity, an epidermal turnover promoting activity, and a cutaneous cell-proliferating effect. The present invention also provides a medicament and a functional food which have a skin aging-inhibiting activity, a collagen-production promoting activity, and a cutaneous cell-proliferation promoting activity. The present invention provides a composition including at least one peptide of Asn-lle-Pro-Pro-Leu, lle-Pro-Pro-Leu, lle-Pro-Pro, Pro-Val-Val-Val-Pro-Pro, Val-Pro-Pro-Phe, Val-Pro-Pro, Phe-Pro-Pro-Gln, and Leu-Pro-Pro-Thr.

    摘要翻译： 本发明提供适合于口服摄取，具有皮肤老化抑制活性，胶原产生促进活性，表皮转换促进活性和皮肤细胞增殖效果的肽和组合物。 本发明还提供了具有皮肤老化抑制活性，胶原产生促进活性和皮肤细胞增殖促进活性的药物和功能性食品。 本发明提供包含至少一种Asn-Lle-Pro-Pro-Leu肽，lle-Pro-Pro-Leu，lle-Pro-Pro，Pro-Val-Val-Val-Pro-Pro，Val- Pro-Pro-Phe，Val-Pro-Pro，Phe-Pro-Pro-Gln和Leu-Pro-Pro-Thr。