Use of hydrogels to fix bone replacements
    7.
    发明授权
    Use of hydrogels to fix bone replacements 失效
    使用水凝胶来修复骨代谢

    公开(公告)号:US5645592A

    公开(公告)日:1997-07-08

    申请号:US341541

    申请日:1995-04-27

    摘要: Provided are orthopedic fasteners and replacements such as nails, screws, pins, hip and knee replacements, etc., coated with hydrogels and other biocompatible/biodegradable materials which expand in the presence of liquids. Swelling of such coatings causes the fastener or replacement to be securely fixed into position once inserted into bone material. Useful coating materials include methacrylates, hyaluronic acid esters, and crosslinked esters of hyaluronic acid resulting from the esterification of hyaluronic acid with polyhydric alcohols. Also provided is a method for fixing a bone or bone replacement in position employing such coated orthopedic fasteners or replacements.

    摘要翻译: PCT No.PCT / EP93 / 01288第 371日期:1995年04月27日 102(e)日期1995年4月27日PCT提交1993年5月21日PCT公布。 公开号WO93 / 23094 日期1997年11月25日提供了在液体存在下膨胀的水凝胶和其他生物相容性/生物可降解材料涂覆的矫形紧固件和替代品,如指甲,螺钉,针,髋关节和膝关节置换等。 这种涂层的膨胀使得紧固件或更换被牢固地固定在一旦插入骨材料中就位。 有用的涂料包括甲基丙烯酸酯,透明质酸酯和由透明质酸与多元醇酯化产生的透明质酸的交联酯。 还提供了一种用于使用这种涂覆的整形外科紧固件或更换来固定骨或骨置换的方法。

    BIOACTIVE AND RESORBABLE SOYBEAN-BASED BIOMATERIALS
    10.
    发明申请
    BIOACTIVE AND RESORBABLE SOYBEAN-BASED BIOMATERIALS 审中-公开
    生物和可再生的大豆生物材料

    公开(公告)号:US20110027364A1

    公开(公告)日:2011-02-03

    申请号:US12744848

    申请日:2008-11-26

    摘要: A method of producing a soybean-based biomaterial which is suitable for use in a biomedical product, the method comprising: defatting soy flour; either prior to or at the same time as, performing a solvent extraction; to produce a biomaterial comprising variable levels of soy proteins, carbohydrates and isoflavones. The resulting biomaterials have a range of biomedical uses and are particularly desirable because of their isoflavone content. Examples of biomedical products containing the biomaterials include wound dressings; scaffolds for tissue engineering; fillers or implants for use in surgery; temporary barriers for use in dental or surgical procedures or to prevent post-surgical tissue adherence; carriers for the delivery of drugs, bioactive peptides or plasmids; anti-inflammatory agents; coatings for wound dressings or for dental, medical, surgical or veterinary devices or implants; and compositions for soothing skin or gum irritation.

    摘要翻译: 一种生产适用于生物医药产品的大豆基生物材料的方法,所述方法包括:脱脂大豆粉; 在进行溶剂萃取之前或同时进行; 以产生包含可变水平的大豆蛋白质,碳水化合物和异黄酮的生物材料。 所得生物材料具有一系列生物医学用途,并且由于它们的异黄酮含量而是特别需要的。 包含生物材料的生物医学产品的实例包括伤口敷料; 组织工程支架; 用于手术的填充物或植入物; 用于牙科或外科手术的临时障碍或防止手术后组织依从性; 用于递送药物,生物活性肽或质粒的载体; 抗炎剂; 用于伤口敷料或牙科,医疗,外科或兽医装置或植入物的涂层; 和用于舒缓皮肤或牙龈刺激的组合物。