Device for treating back pain by re-establishing the exchage of nutrient & waste
    5.
    发明申请
    Device for treating back pain by re-establishing the exchage of nutrient & waste 有权
    通过重新建立营养和废物的交换来治疗背痛的装置

    公开(公告)号:US20060247600A1

    公开(公告)日:2006-11-02

    申请号:US10555895

    申请日:2004-05-07

    IPC分类号: A61M31/00

    摘要: The intervertebral disc is avascular. With aging, endplates become occluded by calcified layers, and diffusion of nutrients and oxygen into the disc diminishes. The disc degenerates, and pain ensues. Conduits are delivered and deployed into the intervertebral disc to reestablish the exchange of nutrients and waste between the disc and bodily circulation to stop or reverse disc degeneration and relieve pain. The intervertebral disc installed with semi-permeable conduits may be used as an immuno-isolated capsule to encapsulate donor cells capable of biosynthesizing therapeutic molecules. The semi-permeable conduits establish the exchange of nutrients and therapeutic molecules between disc and bodily circulation to treat a disease without using immunosuppressive drugs.

    摘要翻译: 椎间盘无血管。 随着老化,终板由钙化层堵塞,营养物质和氧气扩散到椎间盘中减少。 椎间盘退化,发生疼痛。 将管道输送并部署到椎间盘中,以重新建立椎间盘和身体循环之间的营养物质和废物的交换,以停止或逆转椎间盘退变并缓解疼痛。 安装有半渗透管道的椎间盘可以用作免疫分离的囊以封装能够生物合成治疗分子的供体细胞。 半透性管道建立盘与体循环之间的营养物质和治疗分子的交换,以治疗疾病而不使用免疫抑制药物。

    Suture anchor and approximating device
    6.
    发明申请
    Suture anchor and approximating device 有权
    缝合锚和近似装置

    公开(公告)号:US20060030884A1

    公开(公告)日:2006-02-09

    申请号:US10914059

    申请日:2004-08-05

    IPC分类号: A61B17/04

    摘要: An elastically curved suture anchor is resiliently straightened and delivered into tissue by a needle. When the needle is withdrawn, resumption of the curvature provides leverage for anchor rotation as the attached suture is pulled to fasten the anchor within the tissue. A fin at the proximal end of the anchor further increases the rotational leverage and expedites anchor fastening. When two or more anchors with connecting suture are delivered in series on a needle, the tension of the suture helps to draw the anchors together and approximates the pierced tissue.

    摘要翻译: 弹性弯曲的缝合锚固件被弹性地拉直并通过针递送到组织中。 当针被取出时,恢复曲率提供锚定旋转的杠杆作用,因为所附连接的缝合线被拉紧以将锚固件固定在组织内。 在锚的近端处的翅片进一步增加旋转杠杆并加快锚固。 当具有连接缝合线的两个或多个锚固件被串联地递送到针上时,缝合线的张力有助于将锚固件拉到一起并且近似穿刺的组织。

    Disc shunt delivery with stepped needle
    7.
    发明授权
    Disc shunt delivery with stepped needle 有权
    光纤分路输送带阶梯针

    公开(公告)号:US08449490B2

    公开(公告)日:2013-05-28

    申请号:US13199906

    申请日:2011-09-12

    IPC分类号: A61M27/008

    CPC分类号: A61B17/3468 A61B17/7061

    摘要: A solid stepped needle delivers a disc shunt bridging between muscle and a degenerated disc, drawing blood plasma from muscle into the degenerated disc to alleviate back pain and regenerate the disc. The device further includes pull lines attached to the ends of the disc shunt for withdrawing and repositioning the stepped needle during shunt delivery.

    摘要翻译: 固定的步进式针头在肌肉和退化椎间盘之间提供桥接分离器,将血浆从肌肉吸入退化椎间盘以减轻背部疼痛并再生椎间盘。 该装置还包括附接到盘分路的端部的拉线,用于在分流输送期间抽出和重新定位阶梯式针。

    U-shaped disc shunt and delivery device
    8.
    发明申请

    公开(公告)号:US20070169911A1

    公开(公告)日:2007-07-26

    申请号:US11702267

    申请日:2007-02-05

    IPC分类号: B22D19/00

    摘要: The intervertebral disc contains no blood vessels. Nutrients and waste are diffused mainly through adjacent vertebral bodies. As we age, calcified layers form between the disc and vertebral bodies, blocking diffusion. The disc begins to starve and flatten. The weight shifts abnormally from disc to the facet joints causing strain and back pain. Under anaerobic conditions, lactic acid is produced causing acidic irritation and unspecific pain. A U-shaped disc shunt is delivered into and sealed within the degenerated disc simply by needle puncturing and withdrawal, to draw nutrients from bodily circulation into the avascular disc. A continual supply of nutrients increases biosynthesis of the water-retaining sulfated glycosaminoglycans, hence swelling pressure within the disc. The weight is re-shifted from the facet joints to the regenerated disc, alleviating back pain. With oxygen transported through the shunt, anaerobic production of lactic acid is minimized. In addition, the residual lactic acid is expelled through the U-shaped shunt during disc compression into bodily circulation to alleviate unspecific pain.

    U-shaped disc shunt and delivery device
    9.
    发明申请
    U-shaped disc shunt and delivery device 审中-公开
    U形盘分流和输送装置

    公开(公告)号:US20070142791A1

    公开(公告)日:2007-06-21

    申请号:US11702279

    申请日:2007-02-05

    IPC分类号: A61M25/00

    摘要: The intervertebral disc contains no blood vessels. Nutrients and waste are diffused mainly through adjacent vertebral bodies. As we age, calcified layers form between the disc and vertebral bodies, blocking diffusion. The disc begins to starve and flatten. The weight shifts abnormally from disc to the facet joints causing strain and back pain. Under anaerobic conditions, lactic acid is produced causing acidic irritation and unspecific pain. A U-shaped disc shunt is delivered into and sealed within the degenerated disc simply by needle puncturing and withdrawal, to draw nutrients from bodily circulation into the avascular disc. A continual supply of nutrients increases biosynthesis of the water-retaining sulfated glycosaminoglycans, hence swelling pressure within the disc. The weight is re-shifted from the facet joints to the regenerated disc, alleviating back pain. With oxygen transported through the shunt, anaerobic production of lactic acid is minimized. In addition, the residual lactic acid is expelled through the U-shaped shunt during disc compression into bodily circulation to alleviate unspecific pain.

    摘要翻译: 椎间盘不含血管。 营养物和废物主要通过相邻的椎体扩散。 随着年龄的增长,钙化层形成在椎间盘和椎体之间,阻止扩散。 光盘开始变得饿死了。 重量从椎间盘异常移动到小关节,引起应变和背部疼痛。 在厌氧条件下,产生乳酸,引起酸性刺激和非特异性疼痛。 U形盘分流器简单地通过针穿刺和抽出而被输送并退化在退化的椎间盘中,以将营养物从身体循环中吸收到无血管盘中。 持续供应营养物质可增加保水性硫酸糖胺聚糖的生物合成,从而增加盘内的压力。 重量从小关节重新转移到再生椎间盘,减轻背痛。 通过分流运送的氧气,乳酸的厌氧生产被最小化。 另外,残留的乳酸通过U形分流在椎间盘压迫期间被排出到身体循环中以减轻非特异性疼痛。