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公开(公告)号：US07179420B2
公开(公告)日：2007-02-20
申请号：US10280537
申请日：2002-10-25
CPC分类号： B01L3/0268 , B01L2200/0647 , B01L2400/0487 , B01L2400/084 , G01N15/1404 , G01N2015/0065 , G01N2015/0092 , G01N2015/025 , G01N2015/1413 , G01N2015/149 , G01N2015/1493 , Y10T436/117497 , Y10T436/2575
摘要： A particle sorter/dispenser wherein particles that are suspended in a liquid are flowed through a conduit and selectively dispensed through a dispensing orifice. The conduit includes a sensing zone wherein the liquid-suspended particles are interrogated by a sensor. Data from the sensor is received by processing electronics that analyzes the data from the sensor and makes a decision whether or not to dispense a particle. The particle sorter/dispenser further includes a switch that, responsive to a signal from the processing electronics, controls whether or not a given particle is dispensed through the dispensing orifice. The switch has one or two valves that introduce relatively high-pressure liquid into the conduit. The flow streamlines of the high-pressure liquid controls the flow of the relatively low-pressure liquid-suspended particles in the conduit. Particles that are not dispensed are flowed past the dispensing orifice to a recycle reservoir that depends from the downstream end of the conduit.
摘要翻译： 悬浮在液体中的颗粒流过导管并通过分配孔选择性分配的颗粒分选机/分配器。 导管包括感测区域，其中液体悬浮颗粒被传感器询问。 来自传感器的数据由处理电子设备接收，分析来自传感器的数据，并决定是否分配颗粒。 颗粒分选器/分配器还包括开关，其响应于来自处理电子器件的信号来控制是否通过分配孔分配给定的颗粒。 开关具有一个或两个将相对高压液体引入导管的阀。 高压液体的流动流线控制管道中相对低压的液体悬浮颗粒的流动。 未分配的颗粒流过分配孔至从导管的下游端延伸的循环储存器。
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公开(公告)号：US06497155B1
公开(公告)日：2002-12-24
申请号：US09247722
申请日：1999-02-09
IPC分类号： G01N3510
CPC分类号： G01N35/10 , B01J2219/00376 , B01J2219/00414 , B01J2219/00468 , C40B60/14 , G01N15/0272 , G01N35/1074 , G01N2015/1486 , G01N2015/149 , G01N2035/00237 , G01N2035/00574 , G01N2035/1039 , Y10T436/114998 , Y10T436/119163
摘要： In one embodiment, a particle-retrieval device in accordance with the present teachings includes a receiver tube, vacuum-flow providing means and particle-disengaging means. The receiver tube is in fluid communication with the vacuum-flow providing means such that when flow is introduced into the vacuum-flow providing means, a suction or vacuum flow is developed at an end of the receiver tube. The suction causes a particle to adhere to the end of the receiver. A particle is disengaged by discontinuing the suction and, advantageously, by wetting the engaged particle.
摘要翻译： 在一个实施例中，根据本教导的颗粒检索装置包括接收管，真空流提供装置和颗粒分离装置。 接收管与真空流提供装置流体连通，使得当流入真空流提供装置时，吸收管或真空流在接收管的一端形成。 吸力使颗粒粘附到接收器的末端。 通过中断吸力并有利地通过润湿接合的颗粒来分离颗粒。
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公开(公告)号：US06694197B1
公开(公告)日：2004-02-17
申请号：US09556537
申请日：2000-04-24
IPC分类号： G05B1918
CPC分类号： G01N35/109 , G01N35/028 , G01N35/1004 , G01N2035/00237 , G01N2035/0091 , G05B2219/45092
摘要： A single channel reformatter having a syringe that is movable along a z-axis by a z-positioner. A x-y positioner is capable of positioning any well of a source plate having a plurality of wells, and of positioning any well of a destination plate having a plurality of wells, beneath the syringe. Liquid from a well of the source plate is aspirated by the syringe and dispensed into one or more wells of the destination plate. Since the syringe does not move in the x-y plane, it is advantageously integrated into a wash system that cleanses it between liquid transfer operations. The drive element that actuates the syringe to aspirate and dispense during liquid transfer operations is advantageously used to drive the wash cycle. In a method according to present invention for controlling the reformatting operation, well-to-well links are specified, a preferred execution order for executing the specified links is determined, and the specified links are executed in the preferred order.
摘要翻译： 具有可通过z定位器沿Z轴移动的注射器的单通道重新配置器。 x-y定位器能够定位具有多个孔的源板的任何孔，并且在注射器下面定位具有多个孔的目标板的任何孔。 来自源板的孔的液体被注射器吸入并分配到目的板的一个或多个孔中。 由于注射器不在x-y平面内移动，所以有利地将其整合到清洗系统中，以在液体转移操作之间进行清洁。 促进注射器在液体转移操作期间抽吸和分配的驱动元件有利地用于驱动洗涤循环。 在根据本发明的用于控制重新格式化操作的方法中，指定了井对链接，确定用于执行指定链接的优选执行顺序，并且以优选顺序执行指定的链接。
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