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    Method of packaging a beverage
    2.
    发明授权
    Method of packaging a beverage 失效
    包装饮料的方法

    公开(公告)号：US5231816A

    公开(公告)日：1993-08-03

    申请号：US900008

    申请日：1992-06-17

    Applicant: Francis J. Lynch ,  Michael W. Coleman ,  Thomas P. Quinn

    Inventor： Francis J. Lynch ,  Michael W. Coleman ,  Thomas P. Quinn

    IPC: B65B31/02 ,  B65B3/04 ,  B65B31/00 ,  B65D79/00 ,  B65D83/38 ,  B65D85/73 ,  B67C3/00 ,  B67C3/02

    CPC classification number: B65D85/73 ,  B65B3/04 ,  B67C3/02 ,  Y10S220/906

    Abstract: A method of packaging a beverage having gas in solution has an open topped container 1 in which is located a hollow insert 5 having a restricted aperture 12. The container is charged with the beverage such as beer 15 so that the aperture 12 is submerged in the beverage and the container is sealed to form a headspace 19 which is pressurized, preferably by dosing with liquid nitrogen. Following sealing the container is rapidly inverted to locate the aperture 12 in the headspace 19 so that gas pressures in the insert chamber 10 and the headspace 19 come into equilibrium. With the fluid contents in equilibrium, or substantially so, the package is reinverted so that gas under pressure in the insert chamber 10 communicates directly by way of the aperture 12 with beer in the chamber 10. Upon opening of the headspace 19 to atmospheric pressure for dispensing the beer a pressure differential is developed by which gas from the insert chamber 10 is initially ejected through the aperture 12 into the beer 15 to effect in the development of a froth on the beer 15. Beer 30 which may flow into the insert chamber 10 prior to the aperture 12 moving to communication with the headspace 19 is accommodated within a well 13 of the insert chamber 10 remote from the aperture 12 to alleviate the ejection of such beer 30 into the beer 15.

    Abstract translation: 在溶液中包装具有气体的饮料的方法具有敞开的顶部容器1，其中定位有具有限制孔12的中空插入件5.该容器装有诸如啤酒15的饮料，使得孔12浸入 饮料并且容器被密封以形成顶部空间19，顶部空间19被加压，优选地通过用液氮给药。 在密封之后，容器迅速倒置，以将孔12定位在顶部空间19中，使得插入室10和顶部空间19中的气体压力达到平衡。 在流体内容物处于平衡状态或基本上这样的情况下，包装被重新转换，使得在插入室10中的压力下的气体通过孔12直接与室10中的啤酒连通。当将顶部空间19打开至大气压力 分配啤酒，开发压力差，通过该压力差，来自插入室10的气体最初通过孔12喷射到啤酒15中，以实现啤酒15上的泡沫的发展。啤酒30可以流入插入室10 在移动到与顶部空间19连通的孔12之前容纳在远离孔12的插入室10的井13内，以减轻这种啤酒30进入啤酒15中。

    Control systems and methods utilizing object oriented hardware elements
    3.
    发明授权
    Control systems and methods utilizing object oriented hardware elements 失效
    利用面向对象的硬件元素的控制系统和方法

    公开(公告)号：US6154680A

    公开(公告)日：2000-11-28

    申请号：US946231

    申请日：1997-10-07

    Applicant: H. Philip White ,  Thomas P. Quinn ,  James B. Quinn ,  John F. Stine

    Inventor： H. Philip White ,  Thomas P. Quinn ,  James B. Quinn ,  John F. Stine

    IPC: G05B11/01

    CPC classification number: G05B19/042 ,  G05B2219/23304 ,  G05B2219/25229 ,  G05B2219/25428

    Abstract: Computer-based industrial control systems and methods employing object oriented hardware elements. An object oriented hardware element may comprise a processor core coupled one side to a universal real-world interface circuit, and on the other side to an open bus interface. In a preferred embodiment, the open bus interface provides downloading software programming objects to the microprocessor core. A computer-based control system in accordance with the present invention may comprise a personal computer or central processing unit coupled to a communications network, at least one zone interface module coupled to the communications network and to an open bus, at least one zone device module coupled to the open bus and, if required, one or more zone processor modules coupled to the open bus. Software object may be downloaded from the personal computer or central processing unit to the various modules to achieve modular, exception-based, distributively intelligent (MEDI) I/O control within the system.

    Abstract translation: 基于计算机的工业控制系统和采用面向对象的硬件元件的方法。 面向对象的硬件元件可以包括将一侧耦合到通用现实世界接口电路的处理器核心，另一侧耦合到开放式总线接口。 在优选实施例中，开放总线接口向微处理器核提供下载软件编程对象。 根据本发明的基于计算机的控制系统可以包括耦合到通信网络的个人计算机或中央处理单元，耦合到通信网络和开放总线的至少一个区域接口模块，至少一个区域设备模块 耦合到所述开放总线，并且如果需要，耦合到所述开放总线的一个或多个区域处理器模块。 软件对象可以从个人计算机或中央处理单元下载到各种模块，以实现系统内的模块化，基于异常的分布式智能（MEDI）I / O控制。

    Detection of Carbohydrate Biomarkers
    6.
    发明申请
    Detection of Carbohydrate Biomarkers 审中-公开
    检测碳水化合物生物标志物

    公开(公告)号：US20080293161A1

    公开(公告)日：2008-11-27

    申请号：US12187159

    申请日：2008-08-06

    Applicant: Susan L. Deutscher ,  Thomas P. Quinn ,  Edward R. Sauter

    Inventor： Susan L. Deutscher ,  Thomas P. Quinn ,  Edward R. Sauter

    IPC: G01N33/566 ,  G01N33/00

    CPC classification number: G01N33/57415 ,  G01N33/57488 ,  G01N33/66 ,  G01N2400/50

    Abstract: The present invention generally relates to detection of carbohydrate biomarkers in nipple aspirate fluid samples. One aspect of the invention is a method for assaying a nipple aspirate fluid for the presence of TF or Tn carbohydrate biomarker. The assay generally employs an immobilized capture agent specific for TF or Tn and can be further coupled to either direct or indirect detection of bound TF or Tn carbohydrate biomarker through the use of a labeled binding agent.

    Abstract translation: 本发明一般涉及乳头抽吸液样品中碳水化合物生物标志物的检测。 本发明的一个方面是用于测定乳头抽吸液用于存在TF或Tn碳水化合物生物标志物的方法。 该测定通常使用对TF或Tn特异性的固定化捕获剂，并且可以通过使用标记的结合剂进一步偶合直接或间接检测结合的TF或Tn碳水化合物生物标志物。

    ErbB-2 RECEPTOR TARGETING PEPTIDE
    8.
    发明申请
    ErbB-2 RECEPTOR TARGETING PEPTIDE 有权
    ErbB-2受体靶向肽

    公开(公告)号：US20100061930A1

    公开(公告)日：2010-03-11

    申请号：US12555375

    申请日：2009-09-08

    Applicant: Thomas P. Quinn ,  Natalia G. Karasseva

    Inventor： Thomas P. Quinn ,  Natalia G. Karasseva

    IPC: A61K51/00 ,  A61K49/00

    CPC classification number: A61K51/08 ,  A61B5/0071 ,  A61K33/245 ,  A61K38/08 ,  A61K49/0002 ,  A61K49/0045 ,  A61K49/0056 ,  A61K49/10 ,  A61K49/101 ,  A61K51/088 ,  G01N33/57492 ,  G01N33/74

    Abstract: The ErbB-2 receptor, a member of the tyrosine kinase type 1 family of receptors, has been implicated in many human malignancies. Bacteriophage display technology was employed to identify peptides that bound to the extracellular domain of human ErbB-2. The peptide KCCYSL, most frequently occurring in the affinity selected population, was chemically synthesized and characterized for its binding activities to the recombinant extracellular domain of ErbB-2. The synthetic peptide exhibits high specificity to ErbB-2 as well as to ErbB-1, another member of ErbB family. Thus, this peptide can be employed in cancer imaging or therapeutic agent targeting to malignant cells ErbB-2 receptor.

    Abstract translation: ErbB-2受体是1型酪氨酸激酶受体的成员，已经涉及许多人类恶性肿瘤。 使用噬菌体展示技术来鉴定与人ErbB-2细胞外结构域结合的肽。 通过化学方法合成和表征了最常见于亲和选择群体中的肽KCCYSL，其特征在于其与ErbB-2的重组细胞外结构域的结合活性。 合成肽对ErbB-2以及ErbB家族的另一个成员ErbB-1表现出高度的特异性。 因此，该肽可以用于靶向恶性细胞ErbB-2受体的癌症成像或治疗剂。

    Erb-2 receptor targeting peptide
    9.
    发明授权
    Erb-2 receptor targeting peptide 失效
    ErbB-2受体靶向肽

    公开(公告)号：US07585509B2

    公开(公告)日：2009-09-08

    申请号：US10520408

    申请日：2003-07-03

    Applicant: Thomas P. Quinn ,  Natalia G. Karasseva

    Inventor： Thomas P. Quinn ,  Natalia G. Karasseva

    IPC: A61K39/395 ,  A61K51/08 ,  C07K19/00 ,  C07K7/06 ,  A61K38/08

    CPC classification number: A61K51/08 ,  A61B5/0071 ,  A61K33/245 ,  A61K38/08 ,  A61K49/0002 ,  A61K49/0045 ,  A61K49/0056 ,  A61K49/10 ,  A61K49/101 ,  A61K51/088 ,  G01N33/57492 ,  G01N33/74

    Abstract: The ErbB-2 receptor, a member of the tyrosine kinase type 1 family of receptors, has been implicated in many human malignancies. Bacteriophage display technology was employed to identify peptides that bound to the extracellular domain of human ErbB-2. The peptide KCCYSL, most frequently occurring in the affinity selected population, was chemically synthesized and characterized for its binding activities to the recombinant extracellular domain of ErbB-2. The synthetic peptide exhibits high specificity to ErbB-2 as well as to ErbB-1, another member of ErbB family. Thus, this peptide can be employed in cancer imaging or therapeutic agent targeting to malignant cells ErbB-2 receptor.

    Abstract translation: ErbB-2受体是1型酪氨酸激酶受体的成员，已经涉及许多人类恶性肿瘤。 使用噬菌体展示技术来鉴定与人ErbB-2细胞外结构域结合的肽。 通过化学方法合成和表征了最常见于亲和选择群体中的肽KCCYSL，其特征在于其与ErbB-2的重组细胞外结构域的结合活性。 合成肽对ErbB-2以及ErbB家族的另一个成员ErbB-1表现出高度的特异性。 因此，该肽可以用于靶向恶性细胞ErbB-2受体的癌症成像或治疗剂。

    Liquid dispensing system and packaging apparatus which includes such a system
    10.
    发明授权
    Liquid dispensing system and packaging apparatus which includes such a system 失效
    液体分配系统和包装系统的包装设备

    公开(公告)号：US5131440A

    公开(公告)日：1992-07-21

    申请号：US575980

    申请日：1990-08-31

    Applicant: Thomas P. Quinn

    Inventor： Thomas P. Quinn

    IPC: B65B31/00 ,  F17C9/00

    CPC classification number: F17C9/00 ,  B65B31/00 ,  B65B31/006 ,  F17C2201/0104 ,  F17C2201/032 ,  F17C2201/056 ,  F17C2201/058 ,  F17C2221/011 ,  F17C2221/013 ,  F17C2221/014 ,  F17C2221/016 ,  F17C2223/0161 ,  F17C2223/033 ,  F17C2225/0161 ,  F17C2227/044 ,  F17C2260/024 ,  F17C2270/059

    Abstract: A liquid dispensing system and a packaging apparatus which includes such a system has a chamber 6 of a chryogenic vessel 2 containing a reservoir of liquid gas 1 (such as nitrogen, oxygen or argon) which is to be dispensed in doses 26 through an outlet port 12 which is in constant communication with a sub-chamber 17. The sub-chamber 17 is part of a piston 16 and cylindr 15 device in which the piston is reciprocated by means 21 and 24 to expand and contract the sub-chamber. When the sub-chamber 17 is expanded, liquid gas enters from the reservoir 1 through flow ports 18 which are closed by the piston 16 during contraction of the sub-chamber to dispense a dose 26.Mounted beneath the outlet port 12 is a tubular skirt having internal passages 30 through which purging gas directed into the region 29 adjacent to the outlet port 12. The region 29 is purged of air to alleviate ice build-up at the outlet port 12. The purging gas liquifies at a temperature not greater than the temperature of the liquid gas at the outlet port and provides a back-pressure at the outlet port to restrain flow of liquid gas therethrough prior to the contraction of the sub-chamber 17 to dispense a dose.The doses 26 are dispensed into open topped containers that are moved successively beneath the outlet port 12 and means 50 is provided for sensing the containers and controlling the devices 21 and 24 to maintain synchronization between the dispensing and the movement of the containers.

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