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公开(公告)号：US07655189B2
公开(公告)日：2010-02-02
申请号：US11279917
申请日：2006-04-17
申请人： Thomas Willms , Gert Blankenstein
发明人： Thomas Willms , Gert Blankenstein
IPC分类号： B01L3/02
CPC分类号： B01L3/502715 , B01L3/502738 , B01L3/502761 , B01L2200/0668 , B01L2300/0654 , B01L2300/0816 , B01L2300/0825 , B01L2300/0887 , B01L2300/089 , B01L2400/0406 , B01L2400/0421 , B01L2400/0424 , B01L2400/0622 , B01L2400/0633 , B01L2400/0644 , B01L2400/065 , B01L2400/0688
摘要： A device and a process for manipulation of a liquid, the ability of a liquid to flow from a first channel section in a second channel section being temporarily stopped by means of a capillary stop before it flows from the first channel section into the second channel section. Control which is accurate in time is easily enabled by the two channel sections being moved relative to one another for bridging or cancelling the capillary stop, especially being brought into contact.
摘要翻译： 一种用于操纵液体的装置和方法，液体从第二通道部分中的第一通道部分流出的能力在从第一通道部分流入第二通道部分之前通过毛细管停止暂时停止 。 通过两个通道部分相对于彼此移动以便桥接或取消毛细管停止部分，特别是与之接触，容易实现时间准确的控制。
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公开(公告)号：US20050145046A1
公开(公告)日：2005-07-07
申请号：US11008573
申请日：2004-12-10
申请人： Gert Blankenstein , Thomas Willms
发明人： Gert Blankenstein , Thomas Willms
CPC分类号： G01N1/38
摘要： A sampling device and a system for testing of sample liquid are proposed. Very simple and prompt testing of the sample liquid is enabled in that the sampling device has a reservoir for the dilution liquid and that the taken-up sample liquid can be delivered by the dilution liquid directly to the testing area.
摘要翻译： 提出了一种采样装置和一个用于测试样品液体的系统。 采样装置具有用于稀释液体的储存器，并且被抽取的样品液体可以通过稀释液体直接输送到测试区域，因此能够对样品液体进行非常简单和迅速的测试。
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3.发明申请公开(公告)号：US20110088786A1
公开(公告)日：2011-04-21
申请号：US12977516
申请日：2010-12-23
IPC分类号： F15D1/00
CPC分类号： F16K99/0001 , B01L3/50273 , B01L3/502738 , B01L3/502746 , B01L2200/0605 , B01L2200/0621 , B01L2200/0684 , B01L2300/069 , B01L2300/0816 , B01L2300/0864 , B01L2300/087 , B01L2400/0406 , B01L2400/0688 , F16K99/0017 , F16K99/0057 , F16K2099/0074 , F16K2099/0084 , Y10T137/0318 , Y10T137/86389
摘要： A method for manipulating a first liquid within a device including fabricated microstructures for transporting the first liquid through a system of capillary channels and cavities with a closed configuration. The method including transporting the first liquid through the system by capillary force only, stopping a flow of the first liquid temporarily at a capillary stop, switching on the flow of the first liquid after a desired stop time is elapsed, adjusting the stop time of the first liquid by a length and a cross-section of the control capillary between a beginning of the control capillary and its end at the capillary stop, metering the first liquid to be manipulated, and holding a metered amount of the first liquid during the stop time within a cavity.
摘要翻译： 一种用于操纵装置内的第一液体的方法，包括制造的微结构，用于通过具有闭合构型的毛细通道和空腔系统输送第一液体。 该方法包括仅通过毛细管力运送第一液体通过系统，停止毛细管停止时第一液体的流动，在期望的停止时间之后切换第一液体的流动，调整第一液体的停止时间 第一液体在控制毛细管的开始处和毛细管停止之前的控制毛细管的长度和横截面上，计量待操作的第一液体，并在停止时间期间保持计量的第一液体 在一个空腔内
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公开(公告)号：US20060216195A1
公开(公告)日：2006-09-28
申请号：US11340837
申请日：2006-01-27
IPC分类号： G01N31/22
CPC分类号： B01L3/502738 , B01L3/50273 , B01L2200/0605 , B01L2200/0684 , B01L2200/16 , B01L2300/0825 , B01L2300/165 , B01L2400/0406 , B01L2400/0688 , B01L2400/086
摘要： A device and a process for testing a sample liquid wherein the sample liquid flows laminarly by capillary forces over a flat side of a channel to completely filling a reaction area which has a soluble and/or reacting reagent on the flat side and defines a reaction volume of the sample liquid, the reaction volume being temporarily stopped in the reaction area for dissolving or reacting at least 90% of the reagent in the defined reaction volume of the sample liquid, and at least 90% of the dissolved reagent or a reaction product, after stopping, flows together with the reaction volume into the test area which is formed by the channel downstream of the reaction area, the sample liquid flowing with an at least essentially straight liquid front and/or at least essentially without a change in the flow cross section from the reaction area into the test area.
摘要翻译： 一种用于测试样品液体的装置和方法，其中样品液体通过毛细管在通道的平坦侧面上层流地流动，以在平坦侧面上完全填充具有可溶性和/或反应试剂的反应区域，并限定反应体积 的样品液体的反应体积暂时停留在反应区域中，用于使至少90％的试剂溶解或反应在试样液体的规定反应体积中，并且至少90％的溶解试剂或反应产物， 在停止后，与反应体积一起流入由反应区域下游的通道形成的测试区域，样品液体以至少基本上直的液体前部和/或至少基本上没有流动交叉的变化流动 部分从反应区进入试验区。
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公开(公告)号：US20050249641A1
公开(公告)日：2005-11-10
申请号：US11101451
申请日：2005-04-08
CPC分类号： F16K99/0001 , B01L3/50273 , B01L3/502738 , B01L3/502746 , B01L2200/0605 , B01L2200/0621 , B01L2200/0684 , B01L2300/069 , B01L2300/0816 , B01L2300/0864 , B01L2300/087 , B01L2400/0406 , B01L2400/0688 , F16K99/0017 , F16K99/0057 , F16K2099/0074 , F16K2099/0084 , Y10T137/0318 , Y10T137/86389
摘要： A microstructured platform for manipulating a wetting liquid including at least one cavity and a channel system for transporting the liquid. At least some of the channels of the channel system are made as capillaries which have a dimension in the millimeter range or less in at least one direction transverse to the transport direction of the liquid. The platform also includes at least one other microstuctured element disposed in the transport path of the liquid. The microstructured element may be in the form of a fluidic switch, metering means, separating device, or a region for holding together a limited amount of liquid. The structure facilitates or enables the manipulation of liquids when only a small amount of liquid is available and extensive analyses are to be performed with the liquid.
摘要翻译： 一种微结构化平台，用于操纵包括至少一个空腔和用于输送液体的通道系统的润湿液体。 通道系统的至少一些通道被制成毛细管，其在与液体的输送方向横向的至少一个方向上具有在毫米范围内或更小的尺寸。 平台还包括设置在液体的输送路径中的至少一个其它微结构元件。 微结构元件可以是流体开关，计量装置，分离装置或用于保持有限量的液体的区域的形式。 当只有少量的液体可用并且用液体进行广泛的分析时，该结构便于或使得能够操纵液体。
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公开(公告)号：US07318359B2
公开(公告)日：2008-01-15
申请号：US11008573
申请日：2004-12-10
申请人： Gert Blankenstein , Thomas Willms
发明人： Gert Blankenstein , Thomas Willms
IPC分类号： G01N1/00
CPC分类号： G01N1/38
摘要： A sampling device and a system for testing of sample liquid are proposed. Very simple and prompt testing of the sample liquid is enabled in that the sampling device has a reservoir for the dilution liquid and that the taken-up sample liquid can be delivered by the dilution liquid directly to the testing area.
摘要翻译： 提出了一种采样装置和一个用于测试样品液体的系统。 采样装置具有用于稀释液体的储存器，并且被抽取的样品液体可以通过稀释液体直接输送到测试区域，因此能够对样品液体进行非常简单和迅速的测试。
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公开(公告)号：US20060249387A1
公开(公告)日：2006-11-09
申请号：US11279917
申请日：2006-04-17
申请人： Thomas Willms , Gert Blankenstein
发明人： Thomas Willms , Gert Blankenstein
IPC分类号： C07K1/26
CPC分类号： B01L3/502715 , B01L3/502738 , B01L3/502761 , B01L2200/0668 , B01L2300/0654 , B01L2300/0816 , B01L2300/0825 , B01L2300/0887 , B01L2300/089 , B01L2400/0406 , B01L2400/0421 , B01L2400/0424 , B01L2400/0622 , B01L2400/0633 , B01L2400/0644 , B01L2400/065 , B01L2400/0688
摘要： A device and a process for manipulation of a liquid, the ability of a liquid to flow from a first channel section in a second channel section being temporarily stopped by means of a capillary stop before it flows from the first channel section into the second channel section. Control which is accurate in time is easily enabled by the two channel sections being moved relative to one another for bridging or cancelling the capillary stop, especially being brought into contact.
摘要翻译： 一种用于操纵液体的装置和方法，液体从第二通道部分中的第一通道部分流出的能力在从第一通道部分流入第二通道部分之前通过毛细管停止暂时停止 。 通过两个通道部分相对于彼此移动以便桥接或取消毛细管停止部分，特别是与之接触，容易实现时间准确的控制。
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公开(公告)号：US09393766B2
公开(公告)日：2016-07-19
申请号：US13462211
申请日：2012-05-02
申请人： Markus Voigt , Thomas Willms
发明人： Markus Voigt , Thomas Willms
IPC分类号： B32B37/10 , B26F1/02 , B29C65/18 , B29C65/74 , B29C65/00 , B26D7/18 , B29C65/08 , B29C65/48 , B29C65/78
CPC分类号： B32B37/1009 , B26D7/1818 , B26D7/1863 , B26F1/02 , B29C65/08 , B29C65/18 , B29C65/48 , B29C65/7457 , B29C65/7802 , B29C65/7811 , B29C65/7841 , B29C65/7847 , B29C66/0042 , B29C66/00441 , B29C66/02241 , B29C66/1122 , B29C66/1222 , B29C66/1224 , B29C66/472 , B29C66/53461 , B29C66/8122 , B29C66/81425 , B29C66/81427 , B29C66/81429 , B29C66/832 , B29C66/8322 , B29C66/91421 , B29C66/919 , B29C66/929 , B29C66/949 , B29C69/005 , B29C2793/0045 , B29C2793/0081 , B29L2031/756 , Y10T156/17 , B29K2905/12 , B29K2905/10 , B29K2905/00 , B29K2827/18
摘要： Process for joining a foil or a membrane.The invention relates to a method for joining at least one foil-like or membrane-like part to a structural part (9), wherein the foil-like or membrane-like part is separated by means of a tool (2) from a semi-finished product (3) and is held on the tool (2) by applying a reduced pressure, and wherein the foil-like or membrane-like part is placed on the structural part (9), and is in turn held on this (9) and joined to this (9) by applying a reduced pressure.By means of the method a precise, reliable and readily automatable joining of a foil-like or membrane-like part to a structural part (9) is possible.A device (1) is also proposed, with which the method according to the invention can readily be carried out.
摘要翻译： 用于接合箔或膜的方法。 本发明涉及一种用于将至少一个箔状或膜状部分接合到结构部分（9）的方法，其中通过工具（2）将箔状或膜状部分从半 （3），并通过减压保持在工具（2）上，并且其中将箔状或膜状部件放置在结构部件（9）上，并且依次保持在该（ 9），并通过减压加入（9）。 通过该方法，可以将箔状或膜状部件精确，可靠且易于自动化的结合到结构部件（9）。 还提出了一种装置（1），利用该装置可以容易地执行根据本发明的方法。
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公开(公告)号：US06860973B2
公开(公告)日：2005-03-01
申请号：US10287452
申请日：2002-11-04
申请人： Thomas Willms , Jürgen Bruch
发明人： Thomas Willms , Jürgen Bruch
CPC分类号： H01J37/32174 , H01J37/32082 , H01J37/32935 , H01J37/34
摘要： The invention relates to a device for the regulation of a plasma impedance in a vacuum chamber, wherein at least one electrode is connected to an AC generator. This AC generator is a free-running [oscillator], whose frequency adjusts to the resonance frequency of the load upon which it acts. This load comprises fixed circuit elements and a variable plasma impedance. If the plasma impedance is changed, with it the resonance frequency is also changed. The plasma impedance can thus be varied by acquisition of the resonance frequency and by presetting of a reference frequency value, for example thereby that the voltage, the current, the power or the gas inflow is varied as a function of the difference between resonance frequency and reference frequency value.
摘要翻译： 本发明涉及一种用于调节真空室中的等离子体阻抗的装置，其中至少一个电极连接到AC发生器。 该交流发电机是一个自由运行的[振荡器]，其频率根据其作用的负载的谐振频率进行调整。 该负载包括固定电路元件和可变等离子体阻抗。 如果等离子体阻抗发生变化，则谐振频率也会发生变化。 因此，等离子体阻抗可以通过获取谐振频率并通过预设参考频率值而变化，例如由此使电压，电流，功率或气体流入根据共振频率和 参考频率值。
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公开(公告)号：US09610410B2
公开(公告)日：2017-04-04
申请号：US14002024
申请日：2012-02-27
申请人： Thorsten Joedicke , Berthold Lange , Thomas Willms , Ying Yu
发明人： Thorsten Joedicke , Berthold Lange , Thomas Willms , Ying Yu
CPC分类号： A61M5/31596 , A61M5/2448 , A61M5/3146 , A61M5/31511 , A61M35/003 , A61M2005/2451 , A61M2005/2474 , A61M2005/31518 , A61M2205/583 , A61M2207/00
摘要： A device and a method are proposed for actuating a carpule, in which a piston is displaced in the carpule by means of a ram that is telescopically extensible by rotation, and in this way a liquid medicament formulation is expelled. For carrying out different processes, different operating movements are provided, particularly the operation of an operating element in different directions and/or the operation of different operating elements. This promotes simple, intuitive and safe operation.
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