公开(公告)号：US06897322B2

公开(公告)日：2005-05-24

申请号：US10250503

申请日：2002-01-15

申请人： Thorsten Volk ,  Michael Puhl ,  Cyrill Zagar ,  Rene Lochtman ,  Norbert Götz ,  Gerhard Hamprecht

发明人： Thorsten Volk ,  Michael Puhl ,  Cyrill Zagar ,  Rene Lochtman ,  Norbert Götz ,  Gerhard Hamprecht

IPC分类号： C07D231/20 ,  C07D231/14

CPC分类号： C07D231/20

摘要： The invention relates to a method of preparing 1-alkyl-3-aryl-5-difluoromethoxy-1H-pyrazoles of the formula (I), wherein aryl represents a mono- or polysubstituted phenyl ring, and R1 represents C1-C4 alkyl. The inventive method is characterized by reacting, in a first reaction step, a β-ketoester of the general formula (II) with hydrazine and by successively reacting the reaction product obtained with chlorodifluoromethane and a compound R1-L, wherein R1 has the meanings indicated above and L represents the leaving group of a nucleophilic displacement reaction.

摘要翻译： 本发明涉及制备式（I）的1-烷基-3-芳基-5-二氟甲氧基-1H-吡唑的方法，其中芳基表示单取代或多取代的苯环，R 1 >表示C 1 -C 4烷基。 本发明的方法的特征在于在第一反应步骤中使通式（II）的β-酮酯与肼反应，并将所得反应产物与氯二氟甲烷和化合物R 1 - L，其中R 1具有上述含义，L表示亲核置换反应的离去基团。

公开(公告)号：US06888003B2

公开(公告)日：2005-05-03

申请号：US10221206

申请日：2001-03-15

申请人： Cyrill Zagar ,  Robert Reinhard ,  Michael Puhl ,  Thorsten Volk ,  Norbert Götz ,  Gerhard Hamprecht ,  Olaf Menke ,  Ingo Sagasser

发明人： Cyrill Zagar ,  Robert Reinhard ,  Michael Puhl ,  Thorsten Volk ,  Norbert Götz ,  Gerhard Hamprecht ,  Olaf Menke ,  Ingo Sagasser

IPC分类号： C07D231/12 ,  A01N43/56 ,  A01N43/76 ,  C07B61/00 ,  C07D231/16 ,  C07D231/18 ,  C07D413/04 ,  C07D413/14 ,  C07D498/00

CPC分类号： C07D413/04 ,  A01N43/56

摘要： A process for preparing 7-(pyrazol-3-yl)benzoxazoles of the formula I in which the variables R1-R6 are as defined in claim 1, which process is characterized in that a 2-halo-3-(pyrazol-3-yl)anilide of the formula II, in which X is bromine or iodine is reacted with a base in the presence of a transition metal compound of subgroup VIIa, VIIIa or Ib of the Periodic Table of the Elements, is disclosed.

摘要翻译： 制备其中变量R 1〜6的定义的式I的7-（吡唑-3-基）苯并恶唑的方法如权利要求1所定义，该方法 其特征在于式Ⅱ的2-卤代-3-（吡唑-3-基）酰苯胺，其中X是溴或碘，在Ⅶa族，Ⅷa族或Ⅷa族过渡金属化合物存在下与碱反应 公开了元素周期表的Ib。

公开(公告)号：US06268311B1

公开(公告)日：2001-07-31

申请号：US08981049

申请日：1998-03-17

申请人： Olaf Menke ,  Ralf Klintz ,  Gerhard Hamprecht ,  Elisabeth Heistracher ,  Peter Schäfer ,  Cyrill Zagar ,  Norbert Götz ,  Karl-Otto Westphalen ,  Ulf Misslitz ,  Helmut Walter

发明人： Olaf Menke ,  Ralf Klintz ,  Gerhard Hamprecht ,  Elisabeth Heistracher ,  Peter Schäfer ,  Cyrill Zagar ,  Norbert Götz ,  Karl-Otto Westphalen ,  Ulf Misslitz ,  Helmut Walter

IPC分类号： C07D239545

CPC分类号： C07D239/54 ,  A01N43/54 ,  C07C275/24 ,  C07C281/02 ,  C07C281/06

摘要： 1-Amino-3-benzyluracils I (X=oxygen, sulfur; R1=C1-C4-haloalkyl; R2=H, halogen; R3, R7=H, CN, SCN, halogen, C1-C4-haloalkyl, C1-C4-haloalkoxy, C1-C4-haloalkylthio; R4=H, CN, SCN, halogen, C1-C4-alkyl, C1-C4-haloalkyl, C1-C4-alkoxy, C1-C4-haloalkoxy, C1-C4-haloalkylthio, C1-C6-alkylaminocarbonyl; R5=H, CN, NO2, halogen, OH, C1-C4-alkoxy, NH2, C1-C6-alkyl-amino; R6=H, CN, NO2, halogen, OH, C1-C4-alkoxy, NH2, C1-C6-alkyl-amino, CHO) and their salts are used as herbicides and for the desiccation/defoliation of plants.

摘要翻译： 1-氨基-3-苄基脲嘧啶I（X =氧，硫; R1 = C1-C4-卤代烷基; R2 = H，卤素; R3，R7 = H，CN，SCN，卤素，C1-C4卤代烷基， 卤代烷氧基，C 1 -C 4卤代烷硫基，C 1 -C 4卤代烷硫基，C 1 -C 4卤代烷硫基，C 1 -C 4卤代烷硫基，C 1 -C 4卤代烷氧基， -C 1-6烷基氨基羰基; R 5 = H，CN，NO 2，卤素，OH，C 1 -C 4 - 烷氧基，NH 2，C 1 -C 6烷基 - 氨基; R 6 = H，CN，NO 2，卤素，OH， ，NH2，C1-C6-烷基 - 氨基，CHO）及其盐用作除草剂和用于植物的干燥/脱叶。

公开(公告)号：US06528455B1

公开(公告)日：2003-03-04

申请号：US10148909

申请日：2002-06-05

申请人： Gerhard Hamprecht ,  Michael Puhl ,  Robert Reinhard ,  Ingo Sagasser ,  Cyrill Zagar ,  Karl-Otto Westphalen ,  Matthias Witschel ,  Helmut Walter

发明人： Gerhard Hamprecht ,  Michael Puhl ,  Robert Reinhard ,  Ingo Sagasser ,  Cyrill Zagar ,  Karl-Otto Westphalen ,  Matthias Witschel ,  Helmut Walter

IPC分类号： C07D23954

CPC分类号： C07D209/48 ,  C07C205/37 ,  C07C217/84 ,  C07C265/12 ,  C07C331/28 ,  C07D239/54 ,  C07D239/56 ,  C07D251/38

摘要： Phenoxy- and thiophenoxyacrylic acid compounds of the formula I in which Het, R1, R2, R3, V, W and Z are as defined in claim 1 and processes for their preparation, intermediates for their preparation, herbicidally active compositions comprising the compounds of the formula I and a method for controlling harmful fungi are described.

摘要翻译： 其中Het，R1，R2，R3，V，W和Z如权利要求1所定义的式Iin的苯氧基和硫代苯氧基丙烯酸化合物及其制备方法，其制备中间体，除草活性组合物，其包含式 描述了一种控制有害真菌的方法。

公开(公告)号：US20050239655A1

公开(公告)日：2005-10-27

申请号：US10522095

申请日：2003-07-22

申请人： Michael Puhl ,  Gerhard Hamprecht ,  Robert Reinhard ,  Ingo Sagasser ,  Werner Seitz ,  Cyrill Zagar ,  Andreas Landes

发明人： Michael Puhl ,  Gerhard Hamprecht ,  Robert Reinhard ,  Ingo Sagasser ,  Werner Seitz ,  Cyrill Zagar ,  Andreas Landes

IPC分类号： A01N25/30 ,  A01N43/38 ,  A01N43/40 ,  A01N43/54 ,  A01N43/56 ,  A01N43/58 ,  A01N43/64 ,  A01N43/653 ,  A01N43/90 ,  C07D213/61 ,  C07D213/65 ,  C07D231/16 ,  C07D231/18 ,  C07D237/14 ,  C07D237/22 ,  C07D239/54 ,  C07D251/38 ,  A01N43/46

CPC分类号： C07D251/38 ,  C07D213/61 ,  C07D213/65 ,  C07D231/16 ,  C07D231/18 ,  C07D237/14 ,  C07D237/22 ,  C07D239/54

摘要： Disclosed are 3-heterocyclyl substituted benzoic acid derivatives of general formula (I), in which the variables R1 to R8 and X have the meanings indicated in claim 1, and the use thereof as herbicides or for desiccating/defoliating plants.

摘要翻译： 公开了通式（I）的3-杂环基取代的苯甲酸衍生物，其中变量R 1至R 8和X具有权利要求1所示的含义，和 其用作除草剂或用于干燥/脱叶植物。

公开(公告)号：US20070142230A1

公开(公告)日：2007-06-21

申请号：US10581444

申请日：2004-12-17

申请人： Matthias Witschel ,  Michael Puhl ,  Gerhard Hamprecht ,  Liliana Rapado ,  Ulf Missblitz ,  Cyrill Zagar ,  Peter Plath ,  Robert Reinhard ,  Bernd Sievernich ,  Rex Liebl

发明人： Matthias Witschel ,  Michael Puhl ,  Gerhard Hamprecht ,  Liliana Rapado ,  Ulf Missblitz ,  Cyrill Zagar ,  Peter Plath ,  Robert Reinhard ,  Bernd Sievernich ,  Rex Liebl

IPC分类号： A01N37/18 ,  C07C237/42

CPC分类号： C07D213/54 ,  A01N37/48 ,  A01N41/04 ,  A01N47/06 ,  A01N47/12 ,  C07C233/87 ,  C07C237/22 ,  C07C255/60 ,  C07C271/12 ,  C07C271/28 ,  C07C275/24 ,  C07C275/42 ,  C07C309/66 ,  C07C311/06 ,  C07C311/08 ,  C07C311/09 ,  C07C311/53 ,  C07C311/55 ,  C07C323/52 ,  C07C323/60 ,  C07C323/62 ,  C07C323/63 ,  C07D213/80 ,  C07D231/12 ,  C07D239/60 ,  C07D249/08 ,  C07D309/08 ,  C07D317/32 ,  C07D333/24 ,  C07F7/1804

摘要： The present invention relates to benzoyl-substituted phenylalanineamides of the formula I in which the variables R1 to R15 are as defined in the description, and to their agriculturally useful salts, to processes and intermediates for their preparation and to the use of these compounds or of compositions comprising these compounds for controlling unwanted plants.

摘要翻译： 本发明涉及式I的苯甲酰基取代的苯丙氨酰胺，其中变量R 1至R 15如说明书中所定义，以及它们的农业上有用的盐， 涉及其制备方法和中间体，以及这些化合物或包含这些化合物的组合物用于防治有害植物的用途。

公开(公告)号：US07355053B2

公开(公告)日：2008-04-08

申请号：US10531573

申请日：2003-10-17

申请人： Robert Reinhard ,  Gerhard Hamprecht ,  Michael Puhl ,  Werner Seitz ,  Liliana Parra Rapado ,  Annegret Scannell-Lansky ,  Klaus Groβmann ,  Helmut Schiffer ,  Matthias Witschel ,  Cyrill Zagar ,  Andreas Landes ,  Michael Rack

发明人： Robert Reinhard ,  Gerhard Hamprecht ,  Michael Puhl ,  Werner Seitz ,  Liliana Parra Rapado ,  Annegret Scannell-Lansky ,  Klaus Groβmann ,  Helmut Schiffer ,  Matthias Witschel ,  Cyrill Zagar ,  Andreas Landes ,  Michael Rack

IPC分类号： A61K31/402 ,  C07D207/08

CPC分类号： C07D207/277 ,  A01N43/36 ,  C07D207/24 ,  C07D403/06 ,  C07D405/04 ,  C07D409/04

摘要： The invention relates to 1-phenylpyrrolidin-2-one-3-carboxamides of the formula I where the variables R1, R2, R3, X, Y, A, n, Ra, Rb, Rc, Rd and Re are as defined in claim 1 and to their agriculturally useful salts. Moreover, the invention relates to the use of compounds I and/or their salts as herbicides; crop protection compositions comprising at least one 1-phenylpyrrolidin-2-one-3-carboxamide of the formula I and/or at least one agriculturally useful salt of I as active substances; and also a method for controlling unwanted vegetation, which comprises allowing a herbicidally effective amount of at least one 1-phenylpyrrolidin-2-one-3-carboxamide of the formula I or an agriculturally useful salt of I to act on plants, their habitat or on seed.

摘要翻译： 本发明涉及式I的1-苯基吡咯烷-2-酮-3-甲酰胺，其中R 1，R 2，R 3， >，X，Y，A，n，R a，R b，R c，R d，R d和 R e如权利要求1中所定义，和它们的农业上有用的盐。 此外，本发明涉及化合物I和/或其盐作除草剂的用途; 包含式I的至少一种1-苯基吡咯烷-2-酮-3-甲酰胺和/或I的至少一种农业上有用的作为活性物质的盐的作物保护组合物; 以及用于防治有害植物的方法，其包括允许除草有效量的式I的至少一种1-苯基吡咯烷-2-酮-3-甲酰胺或I的农业上有用的盐作用于植物，其栖息地或 在种子上

公开(公告)号：US20060211577A1

公开(公告)日：2006-09-21

申请号：US10551988

申请日：2004-04-06

申请人： Gerhard Hamprecht ,  Michael Puhl ,  Robert Reinhard ,  Werner Seitz ,  Cyrill Zagar ,  Matthias Witschel ,  Andreas Landes

发明人： Gerhard Hamprecht ,  Michael Puhl ,  Robert Reinhard ,  Werner Seitz ,  Cyrill Zagar ,  Matthias Witschel ,  Andreas Landes

IPC分类号： A01N43/54 ,  A01N43/653 ,  A01N43/50 ,  A01N43/56 ,  A01N41/06 ,  C07C313/26 ,  C07C311/29

CPC分类号： C07D239/54 ,  A01N43/40 ,  A01N43/54 ,  A01N43/56 ,  A01N43/58 ,  A01N43/64 ,  A01N43/653 ,  A01N43/707 ,  A01N43/90 ,  A01N47/24 ,  A01N47/34 ,  A01N47/36 ,  A01N47/38 ,  C07D401/12 ,  C07D403/12 ,  C07D405/12 ,  C07D409/12 ,  C07D521/00

摘要： The present invention relates to benzenesulfonamide derivatives of the formula I in which the variables are as defined below: X1 is hydrogen or halogen; X2 is hydrogen, cyano, CS—NH2, halogen, alkyl or haloalkyl; X3 is hydrogen, cyano, alkyl, alkoxyalkyl, cycloalkyl, alkenyl, alkynyl or phenylalkyl, where the phenyl radical for its part may be substituted; Y is a group —C(A)B, SO2 or SO2NR2; A is oxygen or sulfur; B is oxygen, sulfur, NR2 or a bond; R1 is hydrogen, halogen, hydroxy, alkyl, cycloalkyl, cycloalkylalkyl, alkenyl, cycloalkenyl, alkynyl, alkoxy, cycloalkyloxy, alkenyloxy, alkynyloxy, aryl, aryloxy, arylalkyl, where the 13 last mentioned radicals for their part may be substituted; unsubstituted or substituted four- to six-membered heterocyclyl; unsubstituted or substituted four- to six-membered heterocyclyl-C1-C4-alkyl; unsubstituted or substituted five- or six-membered heteroaryl having one to four nitrogen atoms or having one to three nitrogen atoms and one oxygen or one sulfur atom or having one oxygen or sulfur atom; or unsubstituted or substituted five- or six-membered heteroaryl-C1-C4-alkyl having one to four nitrogen atoms or having one to three nitrogen atoms and one oxygen or one sulfur atom or having one oxygen or sulfur atom; R2 is hydrogen,-alkyl, alkenyl, alkynyl, cycloalkyl, where the four last mentioned radicals may be partially or fully halogenated; or R1 and R2 together with the nitrogen atom to which they are attached form an unsubstituted or substituted three- to seven-membered heterocycle; Q is a radical from the group consisting of Q1 to Q39; to processes and intermediates for their preparation and to the use of these compounds or of the compositions comprising these compounds for controlling unwanted plants and for the desiccation/defoliation of plants.

公开(公告)号：US20060019831A1

公开(公告)日：2006-01-26

申请号：US10531573

申请日：2003-10-17

申请人： Robert Reinhard ,  Gerhard Hamprecht ,  Michael Puhl ,  Werner Seitz ,  Liliana Rapado ,  Annegret Scannell-Lansky ,  Klaus Grossmann ,  Helmut Schiffer ,  Matthias Witschel ,  Cyrill Zagar

发明人： Robert Reinhard ,  Gerhard Hamprecht ,  Michael Puhl ,  Werner Seitz ,  Liliana Rapado ,  Annegret Scannell-Lansky ,  Klaus Grossmann ,  Helmut Schiffer ,  Matthias Witschel ,  Cyrill Zagar

IPC分类号： A01N43/36 ,  C07D207/333

CPC分类号： C07D207/277 ,  A01N43/36 ,  C07D207/24 ,  C07D403/06 ,  C07D405/04 ,  C07D409/04

摘要： The invention relates to 1-phenylpyrrolidin-2-one-3-carboxamides of the formula I where the variables R1, R2, R3, X, Y, A, n, Ra, Rb, Rc, Rd and Re are as defined in claim 1 and to their agriculturally useful salts. Moreover, the invention relates to the use of compounds I and/or their salts as herbicides; crop protection compositions comprising at least one 1-phenylpyrrolidin-2-one-3-carboxamide of the formula I and/or at least one agriculturally useful salt of I as active substances; and also a method for controlling unwanted vegetation, which comprises allowing a herbicidally effective amount of at least one 1-phenylpyrrolidin-2-one-3-carboxamide of the formula I or an agriculturally useful salt of I to act on plants, their habitat or on seed.

摘要翻译： 本发明涉及式I的1-苯基吡咯烷-2-酮-3-甲酰胺，其中R 1，R 2，R 3， >，X，Y，A，n，R a，R b，R c，R d，R d和 R e如权利要求1中所定义，和它们的农业上有用的盐。 此外，本发明涉及化合物I和/或其盐作除草剂的用途; 包含式I的至少一种1-苯基吡咯烷-2-酮-3-甲酰胺和/或I的至少一种农业上有用的作为活性物质的盐的作物保护组合物; 以及用于防治有害植物的方法，其包括允许除草有效量的式I的至少一种1-苯基吡咯烷-2-酮-3-甲酰胺或I的农业上有用的盐作用于植物，其栖息地或 在种子上

公开(公告)号：US06639070B1

公开(公告)日：2003-10-28

申请号：US10009836

申请日：2001-12-17

申请人： Gerhard Hamprecht ,  Michael Puhl ,  Olaf Menke ,  Robert Reinhard ,  Ingo Sagasser ,  Cyrill Zagar

发明人： Gerhard Hamprecht ,  Michael Puhl ,  Olaf Menke ,  Robert Reinhard ,  Ingo Sagasser ,  Cyrill Zagar

IPC分类号： C07D27304

CPC分类号： C07D273/00 ,  A01N47/38 ,  A01N57/32 ,  C07D273/04 ,  C07D285/16

摘要： N-substituted perhydro-2,3-diazines of the formula I in which the variables Z, R, m and RA are as defined in claim 1, a process for their preparation and the use of the compounds of the formula I as starting materials for preparing herbicides of the formula V in which R, RA, Z and m are as defined above, X is O or S and Q is a C6-C14-aromatic radical are described.

摘要翻译： 变量Z，R，m和R a如权利要求1所定义的式Iin的N-取代的全氢-2,3-二嗪，其制备方法和式I化合物的用途为 制备式Vin的除草剂的起始原料，其中R，R A，Z和m如上定义，X​​为O或S，Q为C 6 -C 14 - 芳族基团。