摘要:
The present invention relates to a compound, useful as a mineralocorticoid receptor-modulating agent, of the following formula [I]: wherein Ring A is a benzene ring optionally having a substituent(s) other than R1 etc, R1 is a group of the formula: RaSO2NH— etc, Ra is an alkyl group etc, R2 and R3 are each a hydrogen atom, a phenyl group, an optionally substituted alkyl group etc, X is an oxygen atom etc, Y is a group of the formula: —C(═O)— etc, Ar is an optionally substituted aryl group or an optionally substituted heteroaryl group, Q is a single bond, an alkylene group etc, or a pharmaceutically acceptable salt thereof.
摘要翻译:本发明涉及可用作以下式[I]的盐皮质激素受体调节剂的化合物:其中环A为任选具有除R1等以外的取代基的苯环,R1为 式:R a SO 2 NH-等,R a为烷基等,R 2和R 3各自为氢原子,苯基,任意取代的烷基等,X为氧原子等,Y为下式基团-C (= O) - 等,Ar为任选取代的芳基或任选取代的杂芳基,Q为单键,亚烷基等,或其药学上可接受的盐。
摘要:
The present invention relates to a compound, useful as a mineralocorticoid receptor-modulating agent, of the following formula [I]: wherein Ring A is a benzene ring optionally having a substituent(s) other than R1 etc, R1 is a group of the formula: RaSO2NH— etc, Ra is an alkyl group etc, R2 and R3 are each a hydrogen atom, a phenyl group, an optionally substituted alkyl group etc, X is an oxygen atom etc, Y is a group of the formula: —C(═O)— etc, Ar is an optionally substituted aryl group or an optionally substituted heteroaryl group, Q is a single bond, an alkylene group etc, or a pharmaceutically acceptable salt thereof.
摘要翻译:本发明涉及可用作以下式[I]的盐皮质激素受体调节剂的化合物:其中环A为任选具有除R1等以外的取代基的苯环,R1为 式:R a SO 2 NH-等,R a为烷基等,R 2和R 3各自为氢原子,苯基,任意取代的烷基等,X为氧原子等,Y为下式基团-C (= O) - 等,Ar为任选取代的芳基或任选取代的杂芳基,Q为单键,亚烷基等,或其药学上可接受的盐。
摘要:
The present invention relates to a compound, useful as a mineralocorticoid receptor-modulating agent, of the following formula [I]: wherein Ring A is a benzene ring optionally having a substituent(s) other than R1 etc, R1 is a group of the formula: RaSO2NH— etc, Ra is an alkyl group etc, R2 and R3 are each a hydrogen atom, a phenyl group, an optionally substituted alkyl group etc, X is an oxygen atom etc, Y is a group of the formula: —C(═O)— etc, Ar is an optionally substituted aryl group or an optionally substituted heteroaryl group, Q is a single bond, an alkylene group etc, or a pharmaceutically acceptable salt thereof.
摘要翻译:本发明涉及可用作以下式[I]的盐皮质激素受体调节剂的化合物:其中环A为任选具有除R1等以外的取代基的苯环,R1为 式:R a SO 2 NH-等,R a为烷基等,R 2和R 3各自为氢原子,苯基,任意取代的烷基等,X为氧原子等,Y为下式基团-C (= O) - 等,Ar为任选取代的芳基或任选取代的杂芳基,Q为单键,亚烷基等,或其药学上可接受的盐。
摘要:
The present invention relates to a compound, useful as a mineralocorticoid receptor-modulating agent, of the following formula [I]: wherein Ring A is a benzene ring optionally having a substituent(s) other than R1 etc, R1 is a group of the formula: RaSO2NH— etc, Ra is an alkyl group etc, R2 and R3 are each a hydrogen atom, a phenyl group, an optionally substituted alkyl group etc, X is an oxygen atom etc, Y is a group of the formula: —C(═O)— etc, Ar is an optionally substituted aryl group or an optionally substituted heteroaryl group, Q is a single bond, an alkylene group etc, or a pharmaceutically acceptable salt thereof.
摘要翻译:本发明涉及可用作以下式[I]的盐皮质激素受体调节剂的化合物:其中环A为任选具有除R1等以外的取代基的苯环,R1为 式:R a SO 2 NH-等,R a为烷基等,R 2和R 3各自为氢原子,苯基,任意取代的烷基等,X为氧原子等,Y为下式基团-C (-O) - 等,Ar是任选取代的芳基或任选取代的杂芳基,Q是单键,亚烷基等,或其药学上可接受的盐。
摘要:
The invention provides a display method for displaying an image by deposition of metal fine particles. The display method includes at least depositing metal fine particles, from an electrolytic solution that has at least a metal ion of the metal particles and that is provided between a pair of substrates having at least one translucent substrate, onto a surface of any one of the pair of substrates by imparting one stimulus. A concentration of the metal ion of the metal fine particles in the electrolytic solution after imparting the stimulus is about 200 mmol/l or less. The invention further provides a display device which uses the display method.
摘要:
The invention provides a display medium having a dimmer layer which comprises at least two kinds of charged mobile fine particles. Each of the at least two kinds of the charged mobile fine particles respectively has different coloration and a different mobility, and the charged mobile fine particles of at least one kind of the at least two kinds show coloration when in a dispersed state. The invention further provides a display device having an electric field forming unit and the dimmer layer. The invention further provides a display method which uses the display medium and includes putting the charged mobile fine particles of at least one of the kinds being dispersed while having other charged mobile fine particles not being dispersed.
摘要:
The present invention provides display device particles that have positive or negative chargeability and have color and are produced using at least a calcium compound, in which a concentration of the calcium compound in the display device particle is 0.05% by weight or less in terms of a calcium element content, a process for producing the display device particles, as well as an image-display medium and an image-forming device each using the display device particles.
摘要:
Novel indole derivatives of formula (I) or a pharmaceutically acceptable salt thereof: wherein R1 is halogen, or alkyl, R2 is hydrogen, or halogen, Ar is phenyl, or thienyl, which may be substituted with halogen, alkyl, alkoxy, alkylthio, etc.
摘要:
In a method for manufacturing a rotor hub for use in a spindle motor, free-cutting stainless steel is used as a material of the rotor hub. A slug of free-cutting stainless steel is subjected to a plastic working to form a disk mounting portion and a cylindrical surface positioned radially inwardly of the disk mounting portion. Then, a cylindrical disk fitting surface is formed by machining substantially the entirety of the cylindrical surface. The rotor hub contains A-type inclusions appearing in a cross section taken along a center axis of the disk mounting portion. The A-type inclusions are oriented in directions different than the center axis.
摘要:
The present invention relates to compounds represented by formula (1) and a process for producing the same. The use of these compounds can realize the production of carbapenem derivatives having potent antimicrobial activity and a wide antimicrobial spectrum in a safe and cost-effective manner.