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公开(公告)号：US5126434A
公开(公告)日：1992-06-30
申请号：US561762
申请日：1990-08-02
申请人： Toshiaki Osawa , Tadashi Hase , Naonobu Yoshizuka
发明人： Toshiaki Osawa , Tadashi Hase , Naonobu Yoshizuka
IPC分类号： G01N33/53 , A61K39/395 , C07K16/24 , C12N5/10 , C12N15/02 , C12P21/08 , C12R1/91 , G01N33/577
CPC分类号： C07K16/24
摘要： The present invention relates to a monoclonal antibody which specifically binds to a peptide having amino acid sequence (I) described below or having in part at least continuous 4 amino acid sequences of the amino acid sequence (I), and also to a process for producing a monoclonal antibody capable of specifically binding to the peptide represented by the following amino acid sequence:H-Y-Leu-Gly-Arg-X-Asp-Gly-Ser-Glu-OH (I)wherein X represents Glu or Gln and Y represents Trp or Arg.
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公开(公告)号：US5097013A
公开(公告)日：1992-03-17
申请号：US379025
申请日：1989-07-12
摘要： The present invention relates to physiologically active peptides and more particularly, to novel peptides having a specific amino acid sequence which possess a macrophage chemotactic activity.
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公开(公告)号：US5053229A
公开(公告)日：1991-10-01
申请号：US300217
申请日：1989-01-24
IPC分类号： A61K8/96 , A61K8/00 , A61K8/06 , A61K8/34 , A61K8/92 , A61K8/98 , A61K31/00 , A61K35/36 , A61Q19/00
摘要： Novel cosmetic compositions comprising a lipid derived from horny cells can enhance a moisture retention ability of the horny layer and are useful for remedy of dry skin. When the lipid is used in combination with surface active agents, the above effect is enhanced.The cosmetic compositions may take any preparations such as creams, milky lotions, beauty wash, rouges, foundations, hair tonics and the like.
摘要翻译： 包含衍生自角质细胞的脂质的新型化妆品组合物可以增强角质层的保湿能力，并且可用于补救干性皮肤。 当脂质与表面活性剂组合使用时，上述效果得到提高。 化妆品组合物可以采取任何制剂，例如乳膏，乳液，美容洗涤剂，水果，地基，发质等。
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公开(公告)号：US20080181975A1
公开(公告)日：2008-07-31
申请号：US11700200
申请日：2007-01-31
申请人： Naonobu Yoshizuka , Yuko Fukuda , Yasuko Amano , Minoru Takizawa , Hajime Soga , Shinobu Mori , Akira Hachiya
发明人： Naonobu Yoshizuka , Yuko Fukuda , Yasuko Amano , Minoru Takizawa , Hajime Soga , Shinobu Mori , Akira Hachiya
IPC分类号： A61K36/752 , A61K36/00 , A61K36/16 , A61K36/81 , A61P7/00 , A61K36/42 , A61K36/537
CPC分类号： A61K36/752 , A61K36/16 , A61K36/42 , A61K36/537 , A61K36/81
摘要： This invention provides a vasoprotective agent containing a plant or its extract as an effective ingredient. The plant is selected from the group consisting of rosemary, sage, geranium herb, adlai, field horsetail, bitter orange peel, fucus, burdock, dokudami, Japan pepper, Ophiopogon tuber, ginkgo, natsume and dishcloth gourd.
摘要翻译： 本发明提供含有植物或其提取物作为有效成分的血管保护剂。 该植物选自迷迭香，鼠尾草，天竺葵草，ai菜，野马尾，苦橙皮，芦荟，牛蒡，dokudami，日本辣椒，Ophiopogon块茎，银杏，夏烟和抹布葫芦。
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公开(公告)号：US4569931A
公开(公告)日：1986-02-11
申请号：US627549
申请日：1984-07-03
CPC分类号： A61Q19/007 , A61K8/63
摘要： Sebum secretion accelerator composition comprising a cholesteryl ester of a branched fatty acid represented by the formula (I): ##STR1## in which R represents a saturated aliphatic hydrocarbon group having from 11 to 23 carbon atoms and at least one alkyl substituent at a position between the carboxyl bond and the center of the main chain. The cholesteryl ester should be contained not smaller than 25 wt % of the total composition.The composition according to the invention promotes sebum secretion, and is effective in keeping healthy and beautiful skin.The composition is further advantageous in that it can be readily formed into various types of cosmetics such as lotions, creams and ointments.
摘要翻译： 皮脂分泌促进剂组合物，其包含由式（I）表示的支链脂肪酸的胆固醇酯：其中R表示具有11至23个碳原子的饱和脂族烃基和至少一个烷基取代基 羧基键与主链中心之间的位置。 胆固醇酯的含量应不低于总组合物的25重量％。 根据本发明的组合物促进皮脂分泌，并且有效地保持健康和美丽的皮肤。 该组合物的进一步优点在于其可以容易地形成各种类型的化妆品，例如洗剂，霜剂和软膏剂。
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