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公开(公告)号：US20100003540A1
公开(公告)日：2010-01-07
申请号：US12374997
申请日：2007-07-26
CPC分类号： C22C38/02 , B21B1/38 , B23K20/04 , B23K2103/04 , B23K2103/05 , B32B15/011 , C21D9/46 , C22C38/004 , C22C38/04 , C22C38/14 , C22C38/18 , C22C38/40 , C22C38/42 , C22C38/44 , C22C38/46 , Y10T428/12632 , Y10T428/12653 , Y10T428/12965 , Y10T428/12979
摘要： Disclosed is a multilayered steel composite which compatibly achieves properties such as strength and ductility that are incompatible in conventional steels and is excellent in strength, ductility, weldability, toughness and fatigue strength. Also, disclosed is a method for producing the multilayered steel which is produced by rolling with least two kinds of steels having different chemical compositions and microstructure or different mechanical properties, in combination.
摘要翻译： 公开了一种多层钢复合材料，其兼容地实现了在常规钢中不相容并且强度，延展性，焊接性，韧性和疲劳强度优异的强度和延展性等性能。 此外，公开了一种多层钢的制造方法，其通过组合使具有不同化学组成或微结构或不同机械性能的至少两种钢的轧制而制造。
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公开(公告)号：US08137819B2
公开(公告)日：2012-03-20
申请号：US12374997
申请日：2007-07-26
CPC分类号： C22C38/02 , B21B1/38 , B23K20/04 , B23K2103/04 , B23K2103/05 , B32B15/011 , C21D9/46 , C22C38/004 , C22C38/04 , C22C38/14 , C22C38/18 , C22C38/40 , C22C38/42 , C22C38/44 , C22C38/46 , Y10T428/12632 , Y10T428/12653 , Y10T428/12965 , Y10T428/12979
摘要： Disclosed is a multilayered steel composite which compatibly achieves properties such as strength and ductility that are incompatible in conventional steels and is excellent in strength, ductility, weldability, toughness and fatigue strength. Also, disclosed is a method for producing the multilayered steel which is produced by rolling with least two kinds of steels having different chemical compositions and microstructure or different mechanical properties, in combination.
摘要翻译： 公开了一种多层钢复合材料，其兼容地实现了在常规钢中不相容并且强度，延展性，焊接性，韧性和疲劳强度优异的强度和延展性等性能。 此外，公开了一种多层钢的制造方法，其通过组合使具有不同化学组成或微结构或不同机械性能的至少两种钢的轧制而制造。
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公开(公告)号：US08501482B2
公开(公告)日：2013-08-06
申请号：US11798066
申请日：2007-05-10
IPC分类号： G01N33/48
CPC分类号： G01N21/6486 , G01N15/1459 , G01N33/493 , G01N2015/008 , G01N2015/1493 , Y10T436/11 , Y10T436/113332 , Y10T436/114998 , Y10T436/117497 , Y10T436/12
摘要： An apparatus, intended for use in analyzing particles in urine is disclosed, that comprising: a sample distribution section for distributing urine samples to a first aliquot and a second aliquot; a first specimen preparing section for preparing a first specimen for measuring urinary particles, containing at least erythrocytes, by mixing a first stain reagent and the first aliquot; a second specimen preparing section for preparing a second specimen for measuring bacteria by mixing a second stain reagent and the second aliquot; and an optical detecting section comprising a light source for irradiating a light to a specimen being supplied, a scattered light receiving element for detecting scattered light emitted from the specimen, and a fluorescence receiving element for detecting fluorescence emitted from the specimen. A method intended for use in analyzing particles in urine is also disclosed.
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4.发明授权公开(公告)号：US08476066B2
公开(公告)日：2013-07-02
申请号：US12459897
申请日：2009-07-08
申请人： Rumi Takata , Yousuke Tanaka , Noriyuki Narisada , Junya Inoue
发明人： Rumi Takata , Yousuke Tanaka , Noriyuki Narisada , Junya Inoue
CPC分类号： G01N15/1459 , C12Q1/04 , G01N15/1425 , G01N35/00871 , G01N2015/1477 , G01N2015/1486 , G01N2015/1497
摘要： The present invention is to present a bacteria analyzer comprising: a detector comprising: a light source for irradiating light on a measurement sample prepared from a specimen and a reagent; and a light receiving unit for receiving light generated by irradiating the light on the measurement sample from the light source; a scattergram data acquirer for acquiring scattergram data for generating a scattergram having information related to size of the bacteria contained in the specimen and fluorescence information generated by the bacteria as parameters; a bacteria number acquirer for acquiring number of bacteria contained in a plurality of regions on the scattergram for each region; and a form determiner for determining a form of the bacteria contained in the specimen.
摘要翻译： 本发明是提供一种细菌分析装置，其特征在于，包括：检测器，其特征在于，包括：光源，用于对由试样和试剂制备的测定试样照射光; 以及光接收单元，用于接收从光源照射测量样品上的光而产生的光; 散布图数据获取器，用于获取散布图数据，用于生成具有与样本中包含的细菌的大小有关的信息和由细菌产生的荧光信息作为参数的散点图; 用于获取每个区域的散点图上包含在多个区域中的细菌数量的细菌数量获取器; 以及用于确定样品中包含的细菌形式的形式确定器。
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5.发明授权公开(公告)号：US07645594B2
公开(公告)日：2010-01-12
申请号：US10803667
申请日：2004-03-18
CPC分类号： G01N1/30 , C12Q1/04 , G01N2001/302 , Y10T436/108331
摘要： A method of staining bacteria comprises: working a polymethine dye on a sample in the presence of a substance capable of reducing nitrite ions to stain bacteria in the sample. A method of detecting bacteria comprises the following steps of: (1) working a polymethine dye on a sample by a method as described above to stain bacteria in the sample, (2) introducing the thus treated sample into a detecting part of a flow cytometer and irradiating cells of the stained bacteria one by one with light to measure scattered light and fluorescent light emitted from each of the cells; and (3) discriminating the bacteria from other components in accordance with an intensity of a scattered light signal and an intensity of a fluorescent light signal or a pulse width reflecting the length of particles to count the bacteria.
摘要翻译： 染色细菌的方法包括：在能够还原亚硝酸根离子的物质存在下在样品上加工聚甲炔染料以染色样品中的细菌。 检测细菌的方法包括以下步骤：（1）通过上述方法在样品上加工聚甲炔染料以染色样品中的细菌，（2）将如此处理的样品引入流式细胞仪的检测部分 用光照射染色细菌的细胞，测量从每个细胞发出的散射光和荧光; 和（3）根据散射光信号的强度和荧光信号的强度或反映粒子长度的脉冲宽度来区别细菌与其它成分，以计数细菌。
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公开(公告)号：US20090074618A1
公开(公告)日：2009-03-19
申请号：US12283478
申请日：2008-09-12
IPC分类号： B01J19/00
CPC分类号： G01N35/00663 , G01N15/14 , G01N15/1459 , G01N2015/1006 , G01N2015/1402 , G01N2035/0091 , Y10T436/11 , Y10T436/113332 , Y10T436/119163
摘要： A sample analyzer is disclosed that comprises: an analysis section for analyzing a sample by using a reagent; an information receiver for receiving an input of information regarding the reagent; a determination section for determining, whether or not the reagent satisfies a condition to determine that the reagent is a genuine product, based on the information received by the information receiver; and a controller for controlling an operation of the sample analyzer based on a result of the determination by the determination section.
摘要翻译： 公开了一种样品分析仪，其包括：用于通过使用试剂分析样品的分析部分; 用于接收关于试剂的信息的输入的信息接收器; 确定部分，用于基于由信息接收器接收的信息来确定试剂是否满足确定试剂是真品的条件; 以及控制器，用于基于确定部分的确定结果来控制样本分析器的操作。
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公开(公告)号：US20090050821A1
公开(公告)日：2009-02-26
申请号：US11798066
申请日：2007-05-10
CPC分类号： G01N21/6486 , G01N15/1459 , G01N33/493 , G01N2015/008 , G01N2015/1493 , Y10T436/11 , Y10T436/113332 , Y10T436/114998 , Y10T436/117497 , Y10T436/12
摘要： An apparatus, intended for use in analyzing particles in urine is disclosed, that comprising: a sample distribution section for distributing urine samples to a first aliquot and a second aliquot; a first specimen preparing section for preparing a first specimen for measuring urinary particles, containing at least erythrocytes, by mixing a first stain reagent and the first aliquot; a second specimen preparing section for preparing a second specimen for measuring bacteria by mixing a second stain reagent and the second aliquot; and an optical detecting section comprising a light source for irradiating a light to a specimen being supplied, a scattered light receiving element for detecting scattered light emitted from the specimen, and a fluorescence receiving element for detecting fluorescence emitted from the specimen. A method intended for use in analyzing particles in urine is also disclosed.
摘要翻译： 公开了一种用于分析尿液中的颗粒的装置，其包括：用于将尿液样品分配到第一等分试样和第二等分试样的样品分配部分; 第一标本制备部分，用于通过混合第一染色剂和第一等分试样来制备用于测量至少包含红细胞的尿颗粒的第一样本; 第二标本制备部，用于通过混合第二染色剂和第二等分试样来制备用于测量细菌的第二样本; 以及光检测部，其包括用于向被供给的样本照射光的光源，用于检测从样本发射的散射光的散射光接收元件和用于检测从样本发出的荧光的荧光接收元件。 还公开了一种用于分析尿液中颗粒的方法。
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8.发明授权Method of staining, detection and counting bacteria, and a diluent for bacterial stain 有权染色，检测和计数细菌的方法，以及用于细菌染色的稀释剂公开(公告)号：US07309581B2
公开(公告)日：2007-12-18
申请号：US10005753
申请日：2001-10-29
CPC分类号： G01N1/30 , C12Q1/04 , G01N2001/302 , Y10T436/108331
摘要： A method of staining bacteria comprises: working a polymethine dye on a sample in the presence of a substance capable of reducing nitrite ions to stain bacteria in the sample. A method of detecting bacteria comprises the following steps of: (1) working a polymethine dye on a sample by a method as described above to stain bacteria in the sample, (2) introducing the thus treated sample into a detecting part of a flow cytometer and irradiating cells of the stained bacteria one by one with light to measure scattered light and fluorescent light emitted from each of the cells; and (3) discriminating the bacteria from other components in accordance with an intensity of a scattered light signal and an intensity of a fluorescent light signal or a pulse width reflecting the length of particles to count the bacteria.
摘要翻译： 染色细菌的方法包括：在能够还原亚硝酸根离子的物质存在下在样品上加工聚甲炔染料以染色样品中的细菌。 检测细菌的方法包括以下步骤：（1）通过上述方法在样品上加工聚甲炔染料以染色样品中的细菌，（2）将如此处理的样品引入流式细胞仪的检测部分 用光照射染色细菌的细胞，测量从每个细胞发出的散射光和荧光; 和（3）根据散射光信号的强度和荧光信号的强度或反映粒子长度的脉冲宽度来区别细菌与其它成分，以计数细菌。
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公开(公告)号：US6165740A
公开(公告)日：2000-12-26
申请号：US407286
申请日：1999-09-29
申请人： Masakazu Fukuda , Junya Inoue , Akito Terai , Kazuyuki Kanai , Kurayoshi Iseki , Mayumi Kamo
发明人： Masakazu Fukuda , Junya Inoue , Akito Terai , Kazuyuki Kanai , Kurayoshi Iseki , Mayumi Kamo
CPC分类号： G01N15/14 , C12Q1/04 , G01N15/1459 , G01N2015/1402 , G01N2015/1497 , Y10S435/832 , Y10S435/833 , Y10S435/834 , Y10S435/835 , Y10S435/836 , Y10S435/837 , Y10S435/838 , Y10S435/839 , Y10S435/882 , Y10S435/885 , Y10S435/911
摘要： To reduce the effects of the contaminants in the measurement of microorganisms and the reduction of the time necessary for the measurement. Measurement is performed of the microorganism prior to and following culture, and the difference between the two is found. This prevents errors caused by the effect of contaminants contained in the specimens. Since the measurement of the microorganism is performed by means of a flow cytometer, the microorganisms can be measured even when the culture period is short. Moreover, the measurements are accurate, since the contaminants are not measured. Furthermore, the growth form of the microorganisms can be determined by measuring the changes in the intensity of the light emission over the duration of emission of the forward scattered light detected by means of a flow cytometer. Accordingly, based on differences in the particle-size distribution prior to and following culture, it is possible to formulate five major bacterial classifications: Bacilli, Staphylococci, Streptobacilli, Streptococci and yeast fungi.
摘要翻译： 减少污染物在微生物测量中的影响以及减少测量所需的时间。 培养前后培养微生物进行测定，发现两者之间的差异。 这样可以防止样品中含有污染物的影响引起的错误。 由于通过流式细胞仪进行微生物的测定，所以即使在培养期短的情况下也可以测定微生物。 此外，测量是准确的，因为不测量污染物。 此外，微生物的生长形式可以通过测量通过流式细胞仪检测的前向散射光的发射持续时间内的发光强度的变化来确定。 因此，根据培养之前和之后的粒度分布的差异，可以制定五种主要的细菌分类：芽孢杆菌，葡萄球菌，链球菌，链球菌和酵母真菌。
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公开(公告)号：US09086402B2
公开(公告)日：2015-07-21
申请号：US12986887
申请日：2011-01-07
申请人： Rumi Takata , Yousuke Tanaka , Noriyuki Narisada , Junya Inoue
发明人： Rumi Takata , Yousuke Tanaka , Noriyuki Narisada , Junya Inoue
IPC分类号： G06T11/20 , G09G5/22 , G01N33/493 , G01N15/14 , G01N15/00
CPC分类号： G01N33/493 , G01N15/14 , G01N15/1429 , G01N2015/008 , G01N2015/1493
摘要： A sample analyzer comprising: a light source for emitting light to particles contained in a measurement sample which is prepared from a reagent and a urine sample collected from a subject; a detector for detecting scattered light and fluorescence which are generated from the particles in the measurement sample; a display; and a controller, wherein the controller executes operations comprising: obtaining particle data based on the scattered light and the fluorescence which are detected from the particles by the detector; and controlling, when the particle data satisfies a predetermined condition, the display to display information indicating a possibility that the subject is infected with an uncomplicated urinary tract infection is disclosed.
摘要翻译： 1.一种样品分析装置，其特征在于，包括：光源，其对从被检体收集的试剂和尿液样品制备的测定试样中含有的粒子进行发光; 用于检测由测量样品中的颗粒产生的散射光和荧光的检测器; 一个显示器 以及控制器，其中所述控制器执行操作，所述操作包括：基于由所述检测器从所述粒子检测到的散射光和荧光获得粒子数据; 并且当粒子数据满足预定条件时，控制显示器显示指示受试者感染了不复杂的尿路感染的可能性的信息。
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