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    Hyaluronan synthase gene and uses thereof
    1.
    发明申请
    Hyaluronan synthase gene and uses thereof 失效
    透明质酸合酶基因及其用途

    公开(公告)号：US20070087416A1

    公开(公告)日：2007-04-19

    申请号：US11599099

    申请日：2006-11-14

    申请人： Paul Weigel ,  Kshama Kumari ,  Paul DeAngelis

    发明人： Paul Weigel ,  Kshama Kumari ,  Paul DeAngelis

    IPC分类号： C12P19/18 ,  C12P19/28 ,  C08B37/00

    CPC分类号： C12P19/26 ,  A61K39/102 ,  C07H21/04 ,  C08B37/0072 ,  C12N9/1051 ,  C12P19/04 ,  Y10S435/836 ,  Y10S435/839 ,  Y10S435/848

    摘要： The present invention relates to a recombinantly produced, enzymatically active hyaluronan synthase, wherein the recombinantly produced, enzymatically active hyaluronan synthase is a single protein that is a dual-action catalyst that utilizes UDP-GlcA and UDP-GlcNAc to synthesize HA. The recombinantly produced, enzymatically active hyaluronan synthase may be produced from a hyaluronan synthase gene isolated from a microbial source, such as a streptococcal source.

    摘要翻译： 本发明涉及重组产生的酶促活化的透明质酸合酶，其中重组产生的酶活性透明质酸合酶是单一蛋白，其是使用UDP-GlcA和UDP-GlcNAc合成HA的双作用催化剂。 重组产生的酶活性透明质酸合酶可以从分离自微生物来源例如链球菌来源的透明质酸合成酶基因产生。

    HYALURONAN SYNTHASE GENE AND USES THEREOF
    2.
    发明申请
    HYALURONAN SYNTHASE GENE AND USES THEREOF 失效
    HYALURONAN SYNTHASE基因及其用途

    公开(公告)号：US20060216808A1

    公开(公告)日：2006-09-28

    申请号：US11446881

    申请日：2006-06-05

    申请人： Paul Weigel ,  Kshama Kumari ,  Paul DeAngelis

    发明人： Paul Weigel ,  Kshama Kumari ,  Paul DeAngelis

    IPC分类号： C12N9/10 ,  C12N9/24

    CPC分类号： C12P19/26 ,  A61K39/102 ,  C07H21/04 ,  C08B37/0072 ,  C12N9/1051 ,  C12P19/04 ,  Y10S435/836 ,  Y10S435/839 ,  Y10S435/848

    摘要： The present invention relates to a recombinantly produced, enzymatically active hyaluronan synthase, wherein the recombinantly produced, enzymatically active hyaluronan synthase is a single protein that is a dual-action catalyst that utilizes UDP-GlcA and UDP-GlcNAc to synthesize HA. The recombinantly produced, enzymatically active hyaluronan synthase may be produced from a hyaluronan synthase gene isolated from a microbial source, such as a streptococcal source.

    摘要翻译： 本发明涉及重组产生的酶促活化的透明质酸合酶，其中重组产生的酶活性透明质酸合酶是单一蛋白，其是使用UDP-GlcA和UDP-GlcNAc合成HA的双作用催化剂。 重组产生的酶活性透明质酸合酶可以从分离自微生物来源例如链球菌来源的透明质酸合成酶基因产生。

    Disazodyestuffs for ink jet printing
    5.
    发明授权
    Disazodyestuffs for ink jet printing 失效
    用于喷墨打印的双组份

    公开(公告)号：US06746526B1

    公开(公告)日：2004-06-08

    申请号：US10089174

    申请日：2002-03-27

    申请人： Prahalad Manibhai Mistry

    发明人： Prahalad Manibhai Mistry

    IPC分类号： C09D1102

    CPC分类号： C09D11/328 ,  C09B31/08 ,  Y10S435/829 ,  Y10S435/836 ,  Y10T428/24802

    摘要： 1. A compound of Formula (1) and salts thereof: wherein: A is a substituted phenyl group carrying a group of the formula —NR3R4 and an ortho group selected from sulpho, phosphonato and phosphinato; n is 0 or 1; L1 and L2 are each independently H, optionally substituted alkyl, optionally substituted cycloalkyl or optionally substituted aryl, or L1 and L2 together with the N atom to which they are attached form an optionally substituted 5- or 6-membered ring; R1 and R2 are each independently optionally substituted alkyl or optionally substituted alkoxy; and R3 and R4 are each independently H, optionally substituted alkyl, optionally substituted cycloalkyl or optionally substituted aryl, or R3 and R4 together with the nitrogen atom to which they are attached form an optionally substituted 5- or 6-membered ring; or R3 is H, optionally substituted alkyl, optionally substituted cycloalkyl or optionally substituted aryl and R4 is an acyl group. The use of these compounds in inks and the use of inks comprising these compounds in ink jet printing.

    摘要翻译： 1.式（1）的化合物及其盐：其中：A是带有-NR 3 R 4基团的取代苯基和选自磺基，膦酸酯和膦酰基的正基; n是 0或1; L 1和L 2各自独立地为H，任选取代的烷基，任选取代的环烷基或任选取代的芳基，或L 1和L 2与它们所连接的N原子一起 形成任选取代的5-或6-元环; R 1和R 2各自独立地是任选取代的烷基或任选取代的烷氧基; R 3和R 4各自独立地为H，任选取代的烷基，任选取代的环烷基或任选取代的芳基，或R 3和R 4与它们所连接的氮原子一起形成任选取代的 5-或6-元环; 或R 3为H，任选取代的烷基，任选取代的环烷基或任选取代的芳基，R 4为酰基。这些化合物在油墨中的应用以及在喷墨印刷中使用包含这些化合物的油墨。

    Bacillus licheniformis producing antifungal agents and uses thereof for control of phytopathogenic fungi
    10.
    发明授权
    Bacillus licheniformis producing antifungal agents and uses thereof for control of phytopathogenic fungi 失效
    产生地衣芽孢杆菌的抗真菌剂及其用于控制​​植物病原真菌的用途

    公开(公告)号：US5589381A

    公开(公告)日：1996-12-31

    申请号：US268922

    申请日：1994-06-30

    申请人： Carlos A. Neyra ,  Lakshmi Sadasivan

    发明人： Carlos A. Neyra ,  Lakshmi Sadasivan

    IPC分类号： A01N63/00 ,  C12N1/20

    CPC分类号： C12R1/10 ,  A01N63/00 ,  Y10S435/836

    摘要： A Bacillus licheniformis producing an antifungal principle active against a wide variety of plant pathogenic fungi has been isolated. The microorganism was obtained from the rhizosphere of perennial ryegrass (Lolium perenne L.). The type isolate, strain PR1-36a, is particularly antagonistic to filamentous fungi, including Rhizoctonia and Magnaporthe. The microorganism was shown to be effective as a biocontrol agent for control of Fusarium seedling blight in corn. The antifungal principle produced by the microorganism is diffusible and may be purified by acid precipitation of the culture fluid, followed by ethanol extraction. The antifungal principle is fungistatic against several diverse species of fungi, and shows particularly strong activity against filamentous fungi, many of which are serious plant pathogens. Methods are provided for producing and using antifungal strains of Bacillus licheniformis, and antifungal principles produced therefrom, in treatment of soils, planting media, seeds and plant parts for control of various fungal plant diseases.

    摘要翻译： 已经分离出产生针对各种植物致病真菌活性的抗真菌原理的地衣芽孢杆菌。 微生物从多年生黑麦草（Lolium perenne L.）的根际获得。 类型分离株PR1-36a特别拮抗丝状真菌，包括丝核菌丝菌丝菌丝虫菌丝菌丝菌丝虫菌丝菌丝菌 该微生物被证明是有效的用作控制玉米镰刀菌枯萎病的生物防治剂。 由微生物产生的抗真菌原理是可扩散的，可以通过培养液的酸沉淀纯化，然后乙醇提取。 抗真菌原理对几种不同种类的真菌是抑菌的，对丝状真菌具有特别强的活性，其中许多是严重的植物病原体。 提供了用于生产和使用地衣芽孢杆菌的抗真菌菌株的方法，以及由此产生的抗真菌原理，用于处理土壤，种植介质，种子和植物部分以控制各种真菌植物疾病。