公开(公告)号：US20070010026A1

公开(公告)日：2007-01-11

申请号：US11486418

申请日：2006-07-12

Applicant: Hoa Nguyen ,  Trinh Nguyen ,  Duc Nguyen

Inventor： Hoa Nguyen ,  Trinh Nguyen ,  Duc Nguyen

IPC: G01N33/00

CPC classification number: G01N33/6848 ,  H01J49/00 ,  Y10T436/17 ,  Y10T436/173845

Abstract: Method of identification and quantitative analysis of primary and/or secondary amine(s) in a sample by mass spectrometry using stable isotope labeled internal standard is provided. Said internal standard is prepared by reaction of an authentic sample of said amine with a stable isotope labeled reagent, and is added to a sample containing said amine. Said amine in said sample is then quantitatively converted to a chemical compound of identical structure, except the stable isotope atoms, as that of said internal standard using a non-labeled reagent. Said sample is then extracted and the extract is analyzed by mass spectrometry. Identification and quantification of said amine are made from a plot of ion ratio of said converted amine to said internal standard versus amine concentration.

公开(公告)号：US20090245218A1

公开(公告)日：2009-10-01

申请号：US12079977

申请日：2008-03-31

Applicant: Trinh Nguyen

Inventor： Trinh Nguyen

IPC: H04Q7/28

CPC classification number: H04Q3/66 ,  H04Q2213/13034 ,  H04Q2213/13056 ,  H04Q2213/13098 ,  H04Q2213/13141 ,  H04Q2213/13144 ,  H04Q2213/13146 ,  H04Q2213/13164 ,  H04Q2213/13166 ,  H04Q2213/13196 ,  H04Q2213/13332 ,  H04Q2213/13344 ,  H04Q2213/13353 ,  H04Q2213/13389

Abstract: The present invention provides for giving preference to a specific media gateway in the selection of the next circuit so that in a multi-media-gateway soft-switch where a call may take any of many possible paths, an outgoing circuit on the same media-gateway as the incoming circuit is preferably selected, so if one is available, the need for using more bearer ports on media gateways to bridge the two sides is eliminated. Instead of interconnection, the same facilities can be provisioned to the bearer interface between the soft-switch and the rest of the network. This invention maximizes the bearer capacity of a distributed media gateway for external network access.

Abstract translation: 本发明提供了在选择下一个电路时给予特定媒体网关的优先权，使得在多媒体网关软交换机中，呼叫可以采用许多可能的路径中的任何一个，同一媒体上的输出电路， 作为输入电路的网关优选地被选择，因此如果可用，则消除在媒体网关上使用更多承载端口来桥接两侧的需要。 代替互连，可以将相同的设施提供给软交换机和网络的其余部分之间的承载接口。 本发明使用于外部网络接入的分布式媒体网关的承载能力最大化。

公开(公告)号：US20070010025A1

公开(公告)日：2007-01-11

申请号：US11486417

申请日：2006-07-12

Applicant: Hoa Nguyen ,  Trinh Nguyen ,  Duc Nguyen

Inventor： Hoa Nguyen ,  Trinh Nguyen ,  Duc Nguyen

IPC: G01N33/00

CPC classification number: G01N33/6848 ,  H01J49/00 ,  Y10T436/17 ,  Y10T436/173845

Abstract: Method of identification and quantitative analysis of primary and/or secondary amine(s) in a sample by mass spectrometry using stable isotope labeled internal standard is provided. Said internal standard is prepared by reaction of an authentic sample of said amine with a stable isotope labeled reagent, and is added to a sample containing said amine. Said amine in said sample is then quantitatively converted to a chemical compound of identical structure, except the stable isotope atoms, as that of said internal standard using a non-labeled reagent. Said sample is then extracted and the extract is analyzed by mass spectrometry. Identification and quantification of said amine are made from a plot of ion ratio of said converted amine to said internal standard versus amine concentration.

公开(公告)号：US20050079544A1

公开(公告)日：2005-04-14

申请号：US10684249

申请日：2003-10-13

Applicant: Hoa Nguyen ,  Trinh Nguyen ,  Duc Nguyen

Inventor： Hoa Nguyen ,  Trinh Nguyen ,  Duc Nguyen

IPC: C12Q1/26 ,  C40B70/00 ,  G01N33/53 ,  G01N33/543

CPC classification number: C12Q1/26 ,  B01J2219/00581 ,  B01J2219/00702 ,  C40B70/00 ,  G01N2333/90245

Abstract: Method of automated metabolic stability analysis of library of compounds by mass spectrometry using stable isotope labeled internal standards is provided. Said internal standards are prepared in situ by reaction of an authentic sample of said library compounds with a stable isotope labeled reagent. In an automated fashion, cytochrome P450 enzyme systems are added to said library compounds; said reactions are terminated after certain periods of time by addition of an organic solvent containing equal amounts of said labeled internal standards; said terminated enzyme reactions are treated with a non-labeled version of said stable isotope labeled reagent to convert remaining library compounds to compounds of identical structures, except the labeled atoms, as those of said labeled internal standards; said conversion reactions are extracted and the extracts are analyzed by isotope dilution mass spectrometry to determine the percentage of library compounds remaining after enzyme reactions.

Abstract translation: 提供了使用稳定同位素标记的内部标准通过质谱法对化合物文库进行自动化代谢稳定性分析的方法。 所述内标是通过所述文库化合物的真实样品与稳定同位素标记的试剂的反应原位制备的。 以自动化方式，将细胞色素P450酶系统加入到所述文库化合物中; 所述反应通过加入含有等量的所述标记的内标物的有机溶剂在一段时间后终止; 所述终止的酶反应用非标记形式的所述稳定同位素标记的试剂处理，以将剩余的文库化合物转化成除了标记的原子以外的相同结构的化合物，如所述标记的内标物的化合物; 提取所述转化反应，并通过同位素稀释质谱法分析提取物，以确定酶反应后残留的文库化合物的百分比。

公开(公告)号：US08843152B2

公开(公告)日：2014-09-23

申请号：US12079977

申请日：2008-03-31

Applicant: Trinh Nguyen

Inventor： Trinh Nguyen

IPC: H04W72/00 ,  H04Q3/66

CPC classification number: H04Q3/66 ,  H04Q2213/13034 ,  H04Q2213/13056 ,  H04Q2213/13098 ,  H04Q2213/13141 ,  H04Q2213/13144 ,  H04Q2213/13146 ,  H04Q2213/13164 ,  H04Q2213/13166 ,  H04Q2213/13196 ,  H04Q2213/13332 ,  H04Q2213/13344 ,  H04Q2213/13353 ,  H04Q2213/13389

Abstract: The present invention provides for giving preference to a specific media gateway in the selection of the next circuit so that in a multi-media-gateway soft-switch where a call may take any of many possible paths, an outgoing circuit on the same media-gateway as the incoming circuit is preferably selected, so if one is available, the need for using more bearer ports on media gateways to bridge the two sides is eliminated. Instead of interconnection, the same facilities can be provisioned to the bearer interface between the soft-switch and the rest of the network. This invention maximizes the bearer capacity of a distributed media gateway for external network access.

Abstract translation: 本发明提供了在选择下一个电路时给予特定媒体网关的优先权，使得在多媒体网关软交换机中，呼叫可以采用许多可能的路径中的任何一个，同一媒体上的输出电路， 作为输入电路的网关优选地被选择，因此如果可用，则消除在媒体网关上使用更多承载端口来桥接两侧的需要。 代替互连，可以将相同的设施提供给软交换机和网络的其余部分之间的承载接口。 本发明使用于外部网络接入的分布式媒体网关的承载能力最大化。

公开(公告)号：US20070010023A1

公开(公告)日：2007-01-11

申请号：US11486415

申请日：2006-07-12

Applicant: Hoa Nguyen ,  Trinh Nguyen ,  Duc Nguyen

Inventor： Hoa Nguyen ,  Trinh Nguyen ,  Duc Nguyen

IPC: G01N33/00

CPC classification number: G01N33/6848 ,  H01J49/00 ,  Y10T436/17 ,  Y10T436/173845

Abstract: Method of identification and quantitative analysis of primary and/or secondary amine(s) in a sample by mass spectrometry using stable isotope labeled internal standard is provided. Said internal standard is prepared by reaction of an authentic sample of said amine with a stable isotope labeled reagent, and is added to a sample containing said amine. Said amine in said sample is then quantitatively converted to a chemical compound of identical structure, except the stable isotope atoms, as that of said internal standard using a non-labeled reagent. Said sample is then extracted and the extract is analyzed by mass spectrometry. Identification and quantification of said amine are made from a plot of ion ratio of said converted amine to said internal standard versus amine concentration.

Abstract translation: 提供了使用稳定同位素标记的内标通过质谱鉴定和定量分析样品中的一级或二级胺的方法。 所述内标是通过将所述胺的真实样品与稳定同位素标记的试剂反应制备的，并加入含有所述胺的样品中。 然后使用非标记试剂将所述样品中的所述胺定量转化为具有相同结构的化合物，除了稳定的同位素原子，如所述内标的那样。 然后提取所述样品，并通过质谱法分析提取物。 所述胺的鉴定和定量由所述转化的胺与所述内标的离子比对胺浓度的曲线图来制备。

公开(公告)号：US20050070024A1

公开(公告)日：2005-03-31

申请号：US10675765

申请日：2003-09-30

Applicant: Hoa Nguyen ,  Trinh Nguyen ,  Duc Nguyen

Inventor： Hoa Nguyen ,  Trinh Nguyen ,  Duc Nguyen

IPC: G01N33/00 ,  G01N33/60 ,  G01N33/98

CPC classification number: G01N33/60 ,  G01N33/98 ,  H01J49/0009 ,  Y10T436/203332 ,  Y10T436/24

Abstract: Method of identification and quantitative analysis of alcohol(s) in a sample by mass spectrometry using stable isotope labeled internal standard is provided. Said internal standard is prepared by reaction of an authentic sample of said alcohol with a stable isotope labeled reagent, and is added to a sample containing said alcohol. Said alcohol in said sample is then quantitatively converted to a chemical compound of identical structure, except the stable isotope atoms, as that of said internal standard using a non-labeled reagent. Said sample is then extracted and the extract is analyzed by mass spectrometry. Identification and quantification of said alcohol are made from a plot of ion ratio of said converted alcohol to said internal standard versus alcohol concentration.

Abstract translation: 提供使用稳定同位素标记的内标通过质谱鉴定和定量分析样品中的酒精的方法。 所述内标是通过将所述醇的真实样品与稳定同位素标记的试剂反应制备的，并加入含有所述醇的样品中。 然后使用非标记试剂将所述样品中的所述醇定量转化为具有相同结构的化合物，除了稳定的同位素原子，如所述内标的那样。 然后提取所述样品，并通过质谱法分析提取物。 所述醇的鉴定和定量由所述转化的醇与所述内标的离子比与醇浓度的曲线制成。

公开(公告)号：US20050070023A1

公开(公告)日：2005-03-31

申请号：US10675764

申请日：2003-09-30

Applicant: Hoa Nguyen ,  Trinh Nguyen ,  Duc Nguyen

Inventor： Hoa Nguyen ,  Trinh Nguyen ,  Duc Nguyen

IPC: G01N30/72 ,  G01N30/84 ,  G01N33/00 ,  G01N33/24 ,  G01N33/493

CPC classification number: G01N30/7206 ,  G01N33/24 ,  G01N33/493 ,  G01N2030/8429 ,  Y10T436/201666 ,  Y10T436/24

Abstract: Method of identification and quantitative analysis of carboxylic acid (s) in a sample by mass spectrometry using stable isotope labeled internal standard is provided. Said internal standard is prepared by reaction of an authentic sample of said carboxylic acid with a stable isotope labeled reagent, and is added to a sample containing said carboxylic acid. Said carboxylic acid in said sample is then quantitatively converted to a chemical compound of identical structure, except the stable isotope atoms, as that of said internal standard using a non-labeled reagent. Said sample is then extracted and the extract is analyzed by mass spectrometry. Identification and quantification of said carboxylic acid are made from a plot of ion ratio of said converted carboxylic acid to said internal standard versus carboxylic acid concentration.

Abstract translation: 提供了使用稳定同位素标记的内标通过质谱鉴定和定量分析样品中羧酸的方法。 所述内标是通过将所述羧酸的真实样品与稳定同位素标记的试剂反应制备的，并加入含有所述羧酸的样品中。 然后使用未标记的试剂将所述样品中的所述羧酸定量转化为具有相同结构的化合物，除了稳定的同位素原子，如所述内标的那样。 然后提取所述样品，并通过质谱法分析提取物。 所述羧酸的鉴定和定量由所述转化的羧酸与所述内标的离子比相对于羧酸浓度的曲线图来制备。

公开(公告)号：US09940903B2

公开(公告)日：2018-04-10

申请号：US13570013

申请日：2012-08-08

Applicant: John Najarian ,  Gerald Abrahamian ,  Darren Hand ,  Timothy Mohn ,  Lou Houlemarde ,  Daniel Houlemarde ,  Trinh Nguyen

Inventor： John Najarian ,  Gerald Abrahamian ,  Darren Hand ,  Timothy Mohn ,  Lou Houlemarde ,  Daniel Houlemarde ,  Trinh Nguyen

IPC: G09G5/00 ,  G09G5/14

CPC classification number: G09G5/14 ,  G09G2340/145

Abstract: Apparatus and methods for managing, manipulating and presenting data objects within a graphical user interface with variable dimensions, shapes, locations and interactions. The apparatus and methods allow for variable data objects to be both pinned and liquid depending on a larger management and manipulation apparatus. The apparatus consists of databases that store the data objects to be displayed within the user interface and the layout coordinates, variable potential object size, and whether the object can move or not based on the graphical user interface dimensions. The object manipulations include the representation of such objects on the graphical user interface in a defined sequence.

公开(公告)号：US20070061391A1

公开(公告)日：2007-03-15

申请号：US11226040

申请日：2005-09-14

Applicant: Dimitri Tan ,  Trinh Nguyen

Inventor： Dimitri Tan ,  Trinh Nguyen

IPC: G06F7/38

CPC classification number: G06F7/49936

Abstract: A data processor includes a first bit field of a first plurality of bits representing a mantissa of a floating point number and a second bit field of a second plurality of bits representing an exponent of the floating point number. The first plurality of bits is partitioned into a plurality of regions, each of the plurality of regions comprises more than one bit of the first plurality of bits. A leading zero anticipator or other type of leading bit indication circuit is coupled to each region and determines a position of a leading bit of the first plurality of bits. A normalizer is coupled to receive a region of the plurality of regions that contains the leading bit, the normalizer may normalize or denormalize the region to produce a normalized or denormalized floating point number.

Abstract translation: 数据处理器包括表示浮点数的尾数的第一多个比特的第一比特字段和表示浮点数的指数的第二多个比特的第二比特字段。 第一多个比特被划分成多个区域，多个区域中的每一个包括第一多个比特的多于一个比特。 前导零预测器或其他类型的引导位指示电路耦合到每个区域并确定第一多个位的前导位的位置。 归一化器被耦合以接收包含前导位的多个区域的区域，归一化器可以对区域进行归一化或非归一化以产生归一化或非归一化浮点数。