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    Biological photometric device and biological photometry method using same
    1.
    发明授权
    Biological photometric device and biological photometry method using same 有权
    生物光度测定装置及其生物测光方法

    公开(公告)号：US09198624B2

    公开(公告)日：2015-12-01

    申请号：US13806790

    申请日：2011-07-06

    申请人： Tsukasa Funane ,  Hirokazu Atsumori ,  Takusige Katura ,  Masashi Kiguchi ,  Tsuyoshi Takatera ,  Michiyuki Fujiwara

    发明人： Tsukasa Funane ,  Hirokazu Atsumori ,  Takusige Katura ,  Masashi Kiguchi ,  Tsuyoshi Takatera ,  Michiyuki Fujiwara

    IPC分类号： A61B6/00 ,  A61B5/00 ,  G01N21/359 ,  G01N21/49

    CPC分类号： A61B6/00 ,  A61B5/0042 ,  A61B5/0075 ,  A61B5/6814 ,  G01N21/359 ,  G01N21/49

    摘要： The present invention is capable of separating/removing the influence of skin blood flow contained in near infrared spectroscopy (NIRS) signals and extracting a brain- or brain cortex-origin signal. Moreover, the present invention enables versatile separation of brain-origin and skin-origin signals in view of differences among individuals. A biological photometric device, wherein light transmitters and light receivers are located in such a manner that measurement can be conducted at a plurality of source-detector (SD) distances and light received by the individual light-receivers can pass through the gray matter to thereby separate a brain-origin signal and a skin-origin signal. Individual component analysis (ICA) is conducted on data obtained at the individual measurement points. Then, it is determined whether each individual component originates in the brain or in the skin with the use of the SD distance-dependency of the weighted value of each of the separated components.

    摘要翻译： 本发明能够分离/去除包含在近红外光谱（NIRS）信号中的皮肤血流的影响并提取脑或脑皮层起始信号。 此外，鉴于个体之间的差异，本发明能够多功能地分离脑起源和皮肤起始信号。 一种生物测光装置，其中光发射器和光接收器以这样的方式定位，使得可以在多个源 - 检测器（SD）距离处进行测量，并且由各个光接收器接收的光可以通过灰质，从而 分离脑起始信号和皮肤起始信号。 对各个测量点获得的数据进行单独分量分析（ICA）。 然后，使用每个分离的组分的加权值的SD距离相关性来确定每个单独组分是否来自大脑或皮肤。

    BIOLOGICAL PHOTOMETRIC DEVICE AND BIOLOGICAL PHOTOMETRY METHOD USING SAME
    2.
    发明申请
    BIOLOGICAL PHOTOMETRIC DEVICE AND BIOLOGICAL PHOTOMETRY METHOD USING SAME 有权
    生物光学设备和使用相同的生物光度测定方法

    公开(公告)号：US20130102907A1

    公开(公告)日：2013-04-25

    申请号：US13806790

    申请日：2011-07-06

    申请人： Tsukasa Funane ,  Hirokazu Atsumori ,  Takusige Katura ,  Masashi Kiguchi ,  Tsuyoshi Takatera ,  Michiyuki Fujiwara

    发明人： Tsukasa Funane ,  Hirokazu Atsumori ,  Takusige Katura ,  Masashi Kiguchi ,  Tsuyoshi Takatera ,  Michiyuki Fujiwara

    IPC分类号： A61B6/00

    CPC分类号： A61B6/00 ,  A61B5/0042 ,  A61B5/0075 ,  A61B5/6814 ,  G01N21/359 ,  G01N21/49

    摘要： The present invention is capable of separating/removing the influence of skin blood flow contained in near infrared spectroscopy (NIRS) signals and extracting a brain- or brain cortex-origin signal. Moreover, the present invention enables versatile separation of brain-origin and skin-origin signals in view of differences among individuals. A biological photometric device, wherein light transmitters and light receivers are located in such a manner that measurement can be conducted at a plurality of source-detector (SD) distances and light received by the individual light-receivers can pass through the gray matter to thereby separate a brain-origin signal and a skin-origin signal. Individual component analysis (ICA) is conducted on data obtained at the individual measurement points. Then, it is determined whether each individual component originates in the brain or in the skin with the use of the SD distance-dependency of the weighted value of each of the separated components.

    摘要翻译： 本发明能够分离/去除包含在近红外光谱（NIRS）信号中的皮肤血流的影响并提取脑或脑皮层起始信号。 此外，鉴于个体之间的差异，本发明能够多功能地分离脑起源和皮肤起始信号。 一种生物测光装置，其中光发射器和光接收器以这样的方式定位，使得可以在多个源 - 检测器（SD）距离处进行测量，并且由各个光接收器接收的光可以通过灰质，从而 分离脑起始信号和皮肤起始信号。 对各个测量点获得的数据进行单独分量分析（ICA）。 然后，使用每个分离的组分的加权值的SD距离相关性来确定每个单独组分是否来自大脑或皮肤。

    Biological measurement system measuring cerebral blood volume changes to find disease or danger
    7.
    发明授权
    Biological measurement system measuring cerebral blood volume changes to find disease or danger 有权
    生物测量系统测量脑血量变化发现疾病或危险

    公开(公告)号：US08795175B2

    公开(公告)日：2014-08-05

    申请号：US12252809

    申请日：2008-10-16

    申请人： Tsukasa Funane ,  Naoki Tanaka ,  Hideaki Koizumi ,  Atsushi Maki

    发明人： Tsukasa Funane ,  Naoki Tanaka ,  Hideaki Koizumi ,  Atsushi Maki

    IPC分类号： A61B5/00 ,  A61B5/02

    CPC分类号： A61B5/14553 ,  A61B5/02416

    摘要： Cerebral blood volume changes are measured to evaluate, from properties of low-frequency components of such changes and heart rate changes calculated by analysis, a distribution of cerebral blood vessel hardness and its change over time to thereby estimate and display diseased and dangerous portions based on the evaluation. This is attainable by a biological measurement system having a cerebral blood volume measurement unit which measures a regional cerebral blood volume of a body under test, an analyzer unit that analyzes a signal measured by the cerebral blood volume measurement unit, an extraction unit for extracting, based on an output of the analysis unit, information concerning a regional cerebral blood vessel state of the test body, and a display unit which displays a measurement result of the cerebral blood volume measurement unit, an analysis result of the analyzer unit or an extraction result of the extraction unit.

    摘要翻译： 测量脑血容量变化，从这些变化的低频成分的特性和通过分析计算出的心率变化的性质来评估脑血管硬度的分布及其随时间的变化，从而基于以下方式估计和显示患病和危险部分： 评估。 这是通过具有测量被检测体的局部脑血容量的脑血容量测量单元的生物测量系统，分析由脑血容量测量单元测量的信号的分析单元，提取单元， 基于分析单元的输出，关于测试体的区域性脑血管状态的信息和显示脑血容量测量单元的测量结果的显示单元，分析器单元的分析结果或提取结果 的提取单位。