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    Drug delivery compositions for improved stability of steroids
    1.
    发明授权
    Drug delivery compositions for improved stability of steroids 失效
    用于改善类固醇稳定性的药物输送组合物

    公开(公告)号：US5780050A

    公开(公告)日：1998-07-14

    申请号：US504430

    申请日：1995-07-20

    申请人： Uday Jain ,  Srinivasan Venkateshwaran ,  Charles D. Ebert

    发明人： Uday Jain ,  Srinivasan Venkateshwaran ,  Charles D. Ebert

    IPC分类号： A61K9/70 ,  A61K31/565 ,  A61K31/57 ,  A61K47/04 ,  A61K47/10 ,  A61K47/14 ,  A61K47/16 ,  A61K47/20 ,  A61K47/30 ,  A61K47/32 ,  A61K47/44 ,  A61P5/24 ,  A61P5/38 ,  A61F13/00

    CPC分类号： A61K9/7061 ,  A61K31/568 ,  A61K31/569 ,  A61K31/57 ,  A61K31/573 ,  A61K31/575

    摘要： A stabilized patch device for transdermal drug delivery of steroid drugs containing a 3-keto-4-en functional group is described, wherein the patch comprises an effective amount of the steroid drug and a carrier that is free of acid functional groups. The device can further contain additives such as a penetration enhancer or excipient, so long as such additives are also free of acid functional groups. The device can be either a matrix patch or a liquid reservoir patch. In a matrix patch, the carrier is a biocompatible polymeric adhesive with which the steroid drug is intimately admixed. The adhesive is preferably an acrylic polymer or copolymer. In a liquid reservoir patch, the carrier is a controlled-viscosity composition containing a thinner or thickener. Preferred steroid drugs include certain corticosteroids and sex hormones, such as progestins and androgens. A method of stabilizing such steroid drugs during storage in transdermal patches is also disclosed.

    摘要翻译： 描述了一种用于经皮药物递送含有3-酮-4-烯官能团的类固醇药物的稳定补片装置，其中补片包含有效量的类固醇药物和不含酸官能团的载体。 该装置可以进一步含有添加剂如渗透促进剂或赋形剂，只要这些添加剂也不含酸官能团。 该装置可以是矩阵补丁或液体储存器补丁。 在基质贴剂中，载体是与类固醇药物紧密混合的生物相容的聚合物粘合剂。 粘合剂优选为丙烯酸类聚合物或共聚物。 在液体储存贴片中，载体是含有较薄或增稠剂的受控粘度组合物。 优选的类固醇药物包括某些皮质类固醇和性激素，如孕激素和雄激素。 还公开了在透皮贴剂储存期间稳定这种类固醇药物的方法。

    Patient Information Documentation And Management System
    7.
    发明申请
    Patient Information Documentation And Management System 审中-公开
    患者信息文件和管理系统

    公开(公告)号：US20120158432A1

    公开(公告)日：2012-06-21

    申请号：US13323798

    申请日：2011-12-12

    申请人： Uday Jain ,  Manli Zhu ,  Yan Yin ,  Qi Li

    发明人： Uday Jain ,  Manli Zhu ,  Yan Yin ,  Qi Li

    IPC分类号： G06Q50/24

    CPC分类号： G06Q50/24 ,  G06Q10/10

    摘要： A method and system for documenting and managing patient information in real time for accurate medical examination and treatment of a patient is provided. An information carrier device that stores patient information is provided to the patient. A data extraction unit extracts the stored patient information from the information carrier device and transmits the extracted patient information to a patient information processing system. A recording unit records observational data comprising medical examination information and information on treatment prescribed for the patient. The patient information processing system processes and analyzes the patient information received from the information carrier device and/or the data extraction unit and the observational data extracted from the recording unit, generates a medical examination report in one or more of multiple formats, and transmits the medical examination report in one or more formats to the information carrier device for updating the patient information in the information carrier device.

    摘要翻译： 提供了一种用于实时记录和管理患者信息以便对患者进行准确的医学检查和治疗的方法和系统。 向患者提供存储患者信息的信息载体装置。 数据提取单元从信息载体设备提取所存储的患者信息，并将提取的患者信息发送给患者信息处理系统。 记录单元记录包括医学检查信息和关于为患者规定的治疗的信息的观察数据。 患者信息处理系统处理和分析从信息载体设备和/或数据提取单元接收的患者信息和从记录单元提取的观察数据，生成多种格式的一种或多种的医疗检查报告， 一种或多种格式的医疗检查报告给信息载体装置，用于更新信息载体装置中的患者信息。