公开(公告)号：US06820613B2

公开(公告)日：2004-11-23

申请号：US10390408

申请日：2003-03-17

申请人： Ullrich Wenkebach ,  Dieter Weismann

发明人： Ullrich Wenkebach ,  Dieter Weismann

IPC分类号： A61M1500

CPC分类号： A61M16/024 ,  A61M2016/0021 ,  A61M2016/0036 ,  A61M2230/60

摘要： A process is provided for controlling at least one parameter of the breathing gas supply of a respirator with a patient connected to it as well as to a corresponding control device. The respiration pressure, the breathing gas flow generated by the respirator as well as the respiration rate may be used as parameters. The process presents the advantage that the control of the current respiration needs of the patient are taken into account by the muscle pressure (PMUS), i.e., the percentage of the airway pressure caused by the patient's own effort, being maintained at a value close to zero. An airway pressure (PAWC) is first calculated for this purpose from previously measured values for the airway pressure (PAW) and the breathing gas flow (d/dt V) and the mechanical parameters resistance (RL) and compliance (C) of the patient's lungs, which were determined therefrom, and this is subsequently compared with the actually measured value for the airway pressure (PAW). The at least one parameter of the breathing gas supply of the respirator is subsequently controlled on the basis of the comparison between PAWC and PAW, expressed as the muscle pressure PMUS=PAWC−PAW.

摘要翻译： 提供了一种方法，用于控制与患者连接的呼吸器呼吸气体供应的至少一个参数以及相应的控制装置。 呼吸压力，由呼吸器产生的呼吸气体流量以及呼吸速率可用作参数。 该过程提出的优点是通过肌肉压力（P MUS ）考虑到患者的当前呼吸需要的控制，即由患者自己的努力引起的气道压力的百分比 ，维持在接近于零的值。 首先计算气道压力（P AW C），从以前测量的气道压力值（P AW ）和呼吸气体流量（d / dt V ）和由其确定的患者肺的机械参数阻力（RL）和依从性（C），随后将其与气道压力的实际测量值（P AW ）进行比较。 基于P AW C和P AW 之间的比较，随后控制呼吸器呼吸气体供应的至少一个参数，表示为肌肉压力P MUS = P AW CP AW 。

公开(公告)号：US08397720B2

公开(公告)日：2013-03-19

申请号：US12112485

申请日：2008-04-30

申请人： Marcus Eger ,  Dieter Weismann

发明人： Marcus Eger ,  Dieter Weismann

IPC分类号： F16K31/02 ,  A61M16/00

CPC分类号： A61M16/026 ,  A61M2016/0027

摘要： Operating a respirator with an inspiration pressure-vs.-time curve (1), which has an airway target pressure (paw—target) and a PEEP (3), in which the inspiration pressure-vs.-time curve (1) reaches the airway target pressure (paw—target) on a ramp-like curve (17) starting from a starting airway pressure (paw—Start), which is greater than the PEEP (3).

摘要翻译： 操作具有吸气压力 - 时间曲线（1）的呼吸器，其具有气道目标压力（爪 - 目标）和PEEP（3），其中吸气压力 - 时间曲线（1）达到 从起始气道压力（爪启动）开始的斜坡状曲线（17）上的气道目标压力（爪 - 目标）大于PEEP（3）。

公开(公告)号：US08105242B2

公开(公告)日：2012-01-31

申请号：US11675872

申请日：2007-02-16

申请人： Eckhard Teschner ,  Dieter Weismann

发明人： Eckhard Teschner ,  Dieter Weismann

IPC分类号： A61B5/08

CPC分类号： A61B5/0536 ,  A61M16/022 ,  A61M2205/3569 ,  A61M2205/50 ,  A61M2230/65 ,  A61M2230/005

摘要： A process with a corresponding device for lung ventilation involves recording an image of the lung status with an electric impedance tomography (EIT) system (2) and the total area of ventilated lung areas is determined by a computing unit (4) from all image values, subsequently divided into at least two lung areas and the extent of the homogeneity of the ventilated lung areas is determined by comparison of the impedance changes within these areas. In case of a homogeneity rated as being too low, the respiration pressures are increased step by step by means of the respirator (1) and the respiration pressure at which the greatest possible homogeneity is obtained from subsequently determined status images is determined by means of the EIT system (2). The respiration pressure is subsequently lowered again by the respirator (1) until the computing unit (4) detects a reduction in the homogeneity of ventilated lung areas, so that the respiration pressure is subsequently increased again by means of the respirator (1) to the last value at which no reduction in the homogeneity of the ventilated lung areas occurred.

摘要翻译： 具有用于肺通气的相应装置的过程包括用电阻抗断层摄影（EIT）系统（2）记录肺状态的图像，并且通过计算单元（4）从所有图像值确定通气肺区域的总面积 ，随后分为至少两个肺部区域，通过比较这些区域内的阻抗变化来确定通气肺区域的均匀程度。 在均匀性被评定为太低的情况下，呼吸压力通过呼吸器（1）逐步增加，并且从后续确定的状态图像获得最大可能的均匀性的呼吸压力通过 EIT系统（2）。 呼吸压力随后由呼吸器（1）再次降低，直到计算单元（4）检测到通气肺区域的均匀性降低，使得呼吸压力随后通过呼吸器（1）再次增加到 发生通气肺部不均匀的最后一个值。

公开(公告)号：US07882835B2

公开(公告)日：2011-02-08

申请号：US11554905

申请日：2006-10-31

申请人： Marcus Eger ,  Dieter Weismann

发明人： Marcus Eger ,  Dieter Weismann

IPC分类号： A62B7/04 ,  F16K31/26

CPC分类号： A61M16/205 ,  A61M16/026 ,  A61M16/204 ,  A61M2016/0027 ,  A61M2016/0036 ,  A61M2205/15

摘要： A method, system and device are provided for the determination of leaks in a respirator. An inspiraton pressure pinsp is recorded during an inspiration time Tinsp with a measuring device. The inspiration pressure pinsp is varied during consecutive breaths I. Leaks are determined as to leak volumes VLi from the product of pinspi and Tinspi in accordance with the equation VLi=A×pinspiB×Tinspi while the parameters A and B are determined in an analyzing unit by a regression model with pinsp as the regressor.

摘要翻译： 提供了一种用于确定呼吸器泄漏的方法，系统和装置。 在吸气时间Tinsp与测量装置记录灵感压力针脚。 吸气压力针脚在连续呼吸时变化I.泄漏确定为根据等式VLi = A×pinspiB×Tinspi从销钉和Tinspi的产品泄漏体积VLi，而参数A和B在分析单元中确定 通过一个回归模型与pinp作为回归。

公开(公告)号：US5303700A

公开(公告)日：1994-04-19

申请号：US908972

申请日：1992-07-06

申请人： Dieter Weismann ,  Marcel Baum

发明人： Dieter Weismann ,  Marcel Baum

IPC分类号： A61M16/00

CPC分类号： A61M16/00 ,  A61M2016/0021 ,  A61M2016/0036

摘要： The invention relates to a method for recognizing the respiratory phases of a patient for controlling a ventilating apparatus. The time-dependent trace of a signal, which represents the respiratory flow curve and is emitted by a signal device, is determined and from this trace, a trigger criterium is obtained for the switchover of the ventilating apparatus from the expiration phase into the inspiration phase and/or from the inspiration phase into the expiration phase. The method is improved in that even for chronically obstructive patients, a reliable and early recognition of the inspiration and expiration attempts is possible. A significant increase of the slope of the respiratory flow curve between each two zero crossovers of this curve is used as a trigger criterium.

摘要翻译： 本发明涉及一种识别患者呼吸相位的方法，用于控制通气装置。 确定表示呼吸流量曲线并由信号装置发出的信号的时间依赖性迹线，并且从该迹线获得用于从通气装置从呼气阶段切换到吸气阶段的触发标准 和/或从启发阶段进入到期阶段。 该方法得到改进，即使对于慢性阻塞性患者来说，可以早日识别灵感和呼气试验。 作为触发标准，使用该曲线的每两个零交叉点之间的呼吸流量曲线的斜率的显着增加。

公开(公告)号：US08627820B2

公开(公告)日：2014-01-14

申请号：US11754541

申请日：2007-05-29

申请人： Hans Matthiessen ,  Dieter Weismann ,  Marcus Eger

发明人： Hans Matthiessen ,  Dieter Weismann ,  Marcus Eger

IPC分类号： F16K31/02

CPC分类号： A61M16/203 ,  A61B5/085 ,  A61B5/087 ,  A61M16/0069 ,  A61M16/026 ,  A61M16/06 ,  A61M2016/0027 ,  A61M2016/0033

摘要： A device for supplying a patient with breathing gas, in which an initially high initial pressure Paw(t=0) applied from the outside is automatically lowered by means of a control circuit to a lower inspiratory pressure Paw(t) as soon as a pulmonary internal pressure Plung(t) threatens to exceed a predetermined pulmonary target pressure Plung,soll. Overinflation of the lungs due to the respiration is thus ruled out according to the present invention. The device permits, moreover, rapid filling of the lungs with breathing gas and makes thus possible a comparatively long phase of expiration. A process is also provided for regulating a respirator and for respirating a patient.

摘要翻译： 用于向患者提供呼吸气体的装置，其中从外部施加的初始高初始压力Paw（t = 0）一旦肺部被吸入，通过控制电路自动降低到较低的吸气压力Paw（t） 内部压力Plung（t）威胁超过预定的肺部目标压力Plung，soll。 因此根据本发明排除了由呼吸引起的肺的过度充气。 此外，该装置还允许用呼吸气体快速填充肺，并且因此可能达到相对较长的呼气阶段。 还提供了一种用于调节呼吸器和呼吸患者的过程。

公开(公告)号：US07798145B2

公开(公告)日：2010-09-21

申请号：US11461092

申请日：2006-07-31

申请人： Dieter Weismann ,  Hermann Hopermann

发明人： Dieter Weismann ,  Hermann Hopermann

IPC分类号： A62B7/00 ,  F16K31/02

CPC分类号： A61M16/12 ,  A61M16/024 ,  A61M2016/0021 ,  A61M2016/0042

摘要： A respirator for breath-supporting respiration has improved sensitivity of triggering breathing support. A pre-inspiratory inspiratory gas flow is set, which flows off via the expiration valve (9). The closing pressure pv of the expiration valve is measured with a pressure sensor (11) in the process. The gas flow is increased in case of an inspiratory effort of the patient to the extent that the closing pressure pv of the expiration valve (9) is restored. Breath support is generated when the difference between the preset gas flow and the gas flow that is needed to maintain the closing pressure pv at a constant level exceeds a predetermined threshold value.

摘要翻译： 用于呼吸呼吸的呼吸器提高了触发呼吸支持的敏感性。 设置吸气前吸气流，通过呼气阀（9）流出。 过滤阀的关闭压力pv在该过程中用压力传感器（11）测量。 在患者的吸气作用力恢复至止血阀（9）的关闭压力pv的程度的情况下，气体流量增加。 当预设气体流量和维持关闭压力pv达到恒定水平所需的气体流量之间的差异超过预定阈值时，产生呼吸支持。

公开(公告)号：US06260550B1

公开(公告)日：2001-07-17

申请号：US09399721

申请日：1999-09-20

申请人： Dieter Weismann ,  Michael Rehfeldt

发明人： Dieter Weismann ,  Michael Rehfeldt

IPC分类号： A62B902

CPC分类号： A61M16/0045

摘要： A respirator with an inhalation line (5) connected to a gas supply device (2) and with an exhalation line (7) connected to an exhalation device (3), with a Y piece (8) connecting the inhalation line (5) to the exhalation line (7), and with a patient connection (9) going out from the Y piece (8). Partial rebreathing of CO2-containing exhaled air is made possible in a simple manner by providing a switchover device (4) between the inhalation line (5) and the gas supply device (2) as well as between the exhalation line (7) and the exhalation device (3). The switchover device is designed such that the flow connection is established between the inhalation line (5) and the gas supply device (2) as well as the exhalation line (7) and the exhalation device (3) in a first switching position and there is at least a flow connection between the gas supply device (2) and the exhalation line (7) in the second switching position.

摘要翻译： 一种具有与气体供应装置（2）连接的吸入管线（5）和连接到呼气装置（3）的呼气管线（7）的呼吸器，其中Y件（8）将吸入管线（5）连接到 呼气管线（7），以及患者连接（9）从Y件（8）外出。 通过在吸入管线（5）和气体供应装置（2）之间以及在呼气管线（7）和吸入管线（7）之间提供切换装置（4），可以简单地进行部分再呼吸含CO 2的呼出空气。 呼气装置（3）。 切换装置被设计成使得在第一切换位置和那里，在吸入管线（5）和气体供应装置（2）以及呼气管线（7）和呼气装置（3）之间建立流动连接 在第二切换位置中至少是气体供给装置（2）和呼气管线（7）之间的流动连接。

公开(公告)号：US07896814B2

公开(公告)日：2011-03-01

申请号：US11675800

申请日：2007-02-16

申请人： Eckhard Teschner ,  Dieter Weismann

发明人： Eckhard Teschner ,  Dieter Weismann

IPC分类号： A61B5/085

CPC分类号： A61B5/0536 ,  A61M16/022 ,  A61M2205/3569 ,  A61M2205/50 ,  A61M2230/65 ,  A61M2230/005

摘要： An electro-impedance tomography (EIT) system (2), with a computing unit (4) and a respirator (1) is described for gentle mechanical lung ventilation especially in case of atelectases. The presence, the extent and/or the spatial distribution of atelectases is detected by the EIT system (2) and sent to the respirator (1) so that the respiration pressure is increased step by step by the respirator (1) until the current image of the lung status corresponds to a first status image of healthy lungs or comes close to it with minimal deviations. The respiration pressure is subsequently reduced again step by step by the respirator (1) until the computing unit (4) detects a reduction of the ventilated lung areas and the respiration pressure is subsequently increased again by means of the respirator (1) to the last value at which no change occurred in the ventilated lung areas.

摘要翻译： 描述了具有计算单元（4）和呼吸器（1）的电阻抗层析成像（EIT）系统（2），用于轻度机械肺通气，特别是在选择的情况下。 选择酶的存在，程度和/或空间分布由EIT系统（2）检测并发送到呼吸器（1），使得呼吸压力由呼吸器（1）逐步增加，直到当前图像 的肺状态对应于健康肺的第一状态图像或以最小的偏差接近它。 呼吸压力随后由呼吸器（1）逐步减少，直到计算单元（4）检测到通气的肺部区域的减少，并且呼吸压力随后通过呼吸器（1）再次增加到最后 通气肺部无变化的值。

公开(公告)号：US5647351A

公开(公告)日：1997-07-15

申请号：US524535

申请日：1995-09-07

申请人： Dieter Weismann ,  Gregory-Alan Colla ,  Dirk Fiebelkron

发明人： Dieter Weismann ,  Gregory-Alan Colla ,  Dirk Fiebelkron

IPC分类号： A61M16/00 ,  A61M16/20

CPC分类号： A61M16/00 ,  A61M16/204 ,  A61M16/205 ,  A61M2016/0036

摘要： A ventilating system for supplying a patient with respiratory gas has an apparatus for measuring a respiratory gas flow curve 27 and a respiratory gas pressure curve 28 and has an evaluation circuit 8 for processing at least the respiratory gas flow curve and switching over the respiratory phases. As switchover values from one respiratory phase to the other, the evaluation circuit 8 utilizes predetermined trigger thresholds T.sub.IL, T.sub.EL of the respiratory gas flow curve 27. The ventilating system is improved in such a manner that a good adaptation thereof to the breathing effort of the patient 2 is provided even when leakage is present. This task is solved in that, in the evaluation circuit, the respiratory gas flow curve 27 and the respiratory gas pressure curve 28 are logically coupled during both the inspiratory phase and the expiratory phase. This logic operation takes place in accordance with a predetermined function. From the foregoing, an inspiratory trigger ancillary threshold Z.sub.I and an expiratory trigger ancillary threshold Z.sub.E are computed as an additional switchover criterion. These trigger ancillary thresholds Z.sub.I and Z.sub.E are added to the trigger thresholds T.sub.IL and T.sub.EL, respectively. A method for triggering the respiratory phase in the system is also disclosed.

摘要翻译： 用于向患者提供呼吸气体的通风系统具有用于测量呼吸气体流量曲线27和呼吸气体压力曲线28的装置，并且具有至少用于处理呼吸气体流量曲线和切换呼吸相位的评估电路8。 作为从一个呼吸相位到另一个呼吸相位的切换值，评估电路8利用呼吸气体流量曲线27的预定触发阈值TIL，TEL。通气系统被改进，使得其适应于呼吸气体流动曲线 即使存在泄漏，也提供患者2。 解决这个任务的是，在评估电路中，在吸气阶段和呼气阶段期间，呼吸气体流量曲线27和呼吸气体压力曲线28都是逻辑耦合的。 该逻辑操作根据预定功能进行。 根据上述，计算吸气触发辅助阈值ZI和呼气触发辅助阈值ZE作为附加切换标准。 这些触发辅助阈值ZI和ZE分别被添加到触发阈值TIL和TEL。 还公开了一种用于触发系统中的呼吸相的方法。