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公开(公告)号：US20130284326A1
公开(公告)日：2013-10-31
申请号：US13863760
申请日：2013-04-16
发明人： Syed A.M. Tofail , James M. Carlson , Abbasi A. Gandhi , James Butler , Peter Tiernan , Lisa O'Donoghue
IPC分类号： C22F1/10
摘要： A nickel-titanium-rare earth (Ni—Ti-RE) alloy comprises nickel at a concentration of from about 35 at. % to about 65 at. %, a rare earth element at a concentration of from about 1.5 at. % to about 15 at. %, boron at a concentration of up to about 0.1 at. %, with the balance of the alloy being titanium. In addition to enhanced radiopacity compared to binary Ni—Ti alloys and improved workability, the Ni—Ti-RE alloy preferably exhibits superelastic behavior. A method of processing a Ni—Ti-RE alloy includes providing a nickel-titanium-rare earth alloy comprising nickel at a concentration of from about 35 at. % to about 65 at. %, a rare earth element at a concentration of from about 1.5 at. % to about 15 at. %, the balance being titanium; heating the alloy in a homogenization temperature range below a critical temperature; and forming spheroids of a rare earth-rich second phase in the alloy while in the homogenization temperature range.
摘要翻译： 镍 - 钛 - 稀土（Ni-Ti-RE）合金包含浓度为约35at％的镍。 ％至约65英寸 ％，浓度为约1.5at。的稀土元素。 ％至约15英寸 ％，硼浓度高达约0.1at。 ％，合金的余量为钛。 除了与二元Ni-Ti合金相比增强的不透射线性和改进的可加工性之外，Ni-Ti-RE合金优选表现出超弹性行为。 一种加工Ni-Ti-RE合金的方法包括提供镍 - 稀土合金，其包含浓度为约35at％的镍。 ％至约65英寸 ％，浓度为约1.5at。的稀土元素。 ％至约15英寸 ％，余量为钛; 在低于临界温度的均质化温度范围内加热合金; 并且在均质化温度范围内在合金中形成稀土富二烯的球体。
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公开(公告)号：US09074274B2
公开(公告)日：2015-07-07
申请号：US13863760
申请日：2013-04-16
发明人： Syed A. M. Tofail , James M. Carlson , Abbasi A. Gandhi , James Butler , Peter Tiernan , Lisa O'Donoghue
摘要： A nickel-titanium-rare earth (Ni—Ti-RE) alloy comprises nickel at a concentration of from about 35 at. % to about 65 at. %, a rare earth element at a concentration of from about 1.5 at. % to about 15 at. %, boron at a concentration of up to about 0.1 at. %, with the balance of the alloy being titanium. In addition to enhanced radiopacity compared to binary Ni—Ti alloys and improved workability, the Ni—Ti-RE alloy preferably exhibits superelastic behavior. A method of processing a Ni—Ti-RE alloy includes providing a nickel-titanium-rare earth alloy comprising nickel at a concentration of from about 35 at. % to about 65 at. %, a rare earth element at a concentration of from about 1.5 at. % to about 15 at. %, the balance being titanium; heating the alloy in a homogenization temperature range below a critical temperature; and forming spheroids of a rare earth-rich second phase in the alloy while in the homogenization temperature range.
摘要翻译： 镍 - 钛 - 稀土（Ni-Ti-RE）合金包含浓度为约35英寸的镍。 ％至约65英寸 ％，浓度为约1.5at。的稀土元素。 ％至约15英寸 ％，硼浓度高达约0.1at。 ％，合金的余量为钛。 除了与二元Ni-Ti合金相比增强的不透射线性和改进的可加工性之外，Ni-Ti-RE合金优选表现出超弹性行为。 一种加工Ni-Ti-RE合金的方法包括提供镍 - 稀土合金，其包含浓度为约35at％的镍。 ％至约65英寸 ％，浓度为约1.5at。的稀土元素。 ％至约15英寸 ％，余量为钛; 在低于临界温度的均质化温度范围内加热合金; 并且在均质化温度范围内在合金中形成稀土富二烯的球体。
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公开(公告)号：US20180291481A1
公开(公告)日：2018-10-11
申请号：US15978921
申请日：2018-05-14
CPC分类号： C22C19/007 , B22F3/105 , C22C1/0433 , C22C1/0441 , C22C19/03
摘要： A method of forming a sintered nickel-titanium-rare earth (Ni—Ti-RE) alloy includes adding one or more powders comprising Ni, Ti, and a rare earth constituent to a powder consolidation unit comprising an electrically conductive die and punch connectable to a power supply. The one or more powders are heated at a ramp rate of about 35° C./min or less to a sintering temperature, and pressure is applied to the powders at the sintering temperature, thereby forming a sintered Ni—Ti-RE alloy.
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公开(公告)号：US10000827B2
公开(公告)日：2018-06-19
申请号：US13656151
申请日：2012-10-19
CPC分类号： C22C19/007 , B22F3/105 , C22C1/0433 , C22C1/0441 , C22C19/03
摘要： A method of forming a sintered nickel-titanium-rare earth (Ni—Ti-RE) alloy includes adding one or more powders comprising Ni, Ti, and a rare earth constituent to a powder consolidation unit comprising an electrically conductive die and punch connectable to a power supply. The one or more powders are heated at a ramp rate of about 35° C./min or less to a sintering temperature, and pressure is applied to the powders at the sintering temperature, thereby forming a sintered Ni—Ti-RE alloy.
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5.发明申请MIXTURE OF POWDERS FOR PREPARING A SINTERED NICKEL-TITANIUM-RARE EARTH METAL (Ni-Ti-RE) ALLOY 有权用于制备烧结镍 - 稀土金属（Ni-Ti-RE）合金的粉末混合物公开(公告)号：US20130183188A1
公开(公告)日：2013-07-18
申请号：US13744950
申请日：2013-01-18
发明人： Syed A. M. Tofail , James Butler , James M. Carlson , Garry Warren , Abbasi A. Gandhi , Peter Tiernan
CPC分类号： C22C30/00 , B22F3/10 , B22F3/12 , B22F3/14 , B22F3/24 , B22F2301/155 , C22C1/04 , C22C1/045 , C22C19/03
摘要： A mixture of powders for preparing a sintered nickel-titanium-rare earth (Ni—Ti—RE) alloy includes Ni—Ti alloy powders comprising from about 55 wt. % Ni to about 61 wt. % Ni and from about 39 wt. % Ti to about 45 wt. % Ti, and RE alloy powders comprising a RE element.
摘要翻译： 用于制备镍 - 钛 - 稀土（Ni-Ti-RE）烧结合金的粉末混合物包括Ni-Ti合金粉末，其包含约55wt。 ％Ni至约61wt。 ％Ni和约39wt。 ％Ti至约45wt。 ％Ti和包含RE元素的RE合金粉末。
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公开(公告)号：US10563291B2
公开(公告)日：2020-02-18
申请号：US15978921
申请日：2018-05-14
摘要： A method of forming a sintered nickel-titanium-rare earth (Ni—Ti-RE) alloy includes adding one or more powders comprising Ni, Ti, and a rare earth constituent to a powder consolidation unit comprising an electrically conductive die and punch connectable to a power supply. The one or more powders are heated at a ramp rate of about 35° C./min or less to a sintering temperature, and pressure is applied to the powders at the sintering temperature, thereby forming a sintered Ni—Ti-RE alloy.
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7.发明授权Mixture of powders for preparing a sintered nickel-titanium-rare earth metal (Ni-Ti-RE) alloy 有权用于制备镍 - 钛 - 稀土金属（Ni-Ti-RE）烧结合金粉末的混合物公开(公告)号：US09212409B2
公开(公告)日：2015-12-15
申请号：US13744950
申请日：2013-01-18
发明人： Syed A. M. Tofail , James Butler , James M. Carlson , Garry Warren , Abbasi A. Gandhi , Peter Tiernan
CPC分类号： C22C30/00 , B22F3/10 , B22F3/12 , B22F3/14 , B22F3/24 , B22F2301/155 , C22C1/04 , C22C1/045 , C22C19/03
摘要： A mixture of powders for preparing a sintered nickel-titanium-rare earth (Ni—Ti—RE) alloy includes Ni—Ti alloy powders comprising from about 55 wt. % Ni to about 61 wt. % Ni and from about 39 wt. % Ti to about 45 wt. % Ti, and RE alloy powders comprising a RE element.
摘要翻译： 用于制备镍 - 钛 - 稀土（Ni-Ti-RE）烧结合金的粉末混合物包括Ni-Ti合金粉末，其包含约55wt。 ％Ni至约61wt。 ％Ni和约39wt。 ％Ti至约45wt。 ％Ti和包含RE元素的RE合金粉末。
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8.发明申请公开(公告)号：US20130101455A1
公开(公告)日：2013-04-25
申请号：US13656151
申请日：2012-10-19
CPC分类号： C22C19/007 , B22F3/105 , C22C1/0433 , C22C1/0441 , C22C19/03
摘要： A method of forming a sintered nickel-titanium-rare earth (Ni—Ti-RE) alloy includes adding one or more powders comprising Ni, Ti, and a rare earth constituent to a powder consolidation unit comprising an electrically conductive die and punch connectable to a power supply. The one or more powders are heated at a ramp rate of about 35° C./min or less to a sintering temperature, and pressure is applied to the powders at the sintering temperature, thereby forming a sintered Ni—Ti-RE alloy.
摘要翻译： 形成镍 - 钛 - 稀土（Ni-Ti-RE）烧结合金的方法包括将一种或多种包含Ni，Ti和稀土成分的粉末添加到包括导电性模具和可连接到 电源。 将一种或多种粉末以约35℃/分钟以下的升温速度加热至烧结温度，并在烧结温度下向粉末施加压力，从而形成Ni-Ti-RE合金烧结体。
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公开(公告)号：US11759552B2
公开(公告)日：2023-09-19
申请号：US15899436
申请日：2018-02-20
发明人： John Neilan , David Murray , James Butler
IPC分类号： A61L31/08 , A61L31/16 , A61L31/02 , A61L27/04 , A61L27/30 , A61L27/54 , B05D3/12 , A61F2/915 , A61F2/90
CPC分类号： A61L31/084 , A61L27/04 , A61L27/303 , A61L27/54 , A61L31/022 , A61L31/16 , B05D3/12 , A61F2/90 , A61F2/915 , A61L2300/416 , A61L2400/18 , A61L2420/02
摘要： There is disclosed a method of improving the reliability of coating an implantable medical device, such as a stent, with bioactive material in the absence of a carrier material such as a matrix or polymer layer. The method involves cleaning volatile components from the exposed surfaces of the medical device, removing carbon deposits and then applying a uniform carbon layer in a controlled environment. The deliberately applied carbon layer masks impurities of the underlying native oxide layer and leads to more uniform bioactive material coating not only a over the surfaces of a single medical device but also from device to device within a batch and between batches of devices. This improves production as well as optimising the amount and release of drug on the medical device without the need for a carrier material.
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公开(公告)号：US11504253B2
公开(公告)日：2022-11-22
申请号：US16413132
申请日：2019-05-15
发明人： Olivia Ryan , James Butler , Joe Hayes , Sean Cummins
摘要： A vascular intervention device delivery system includes a catheter with a proximal end attached to a handle, and a distal carrier segment for mounting a vascular intervention device thereon. A retractable sheath is movable from a first position covering the distal carrier segment to a second position retracted proximally uncovering the distal carrier segment. A pull is attached to the retractable sheath and extends proximally from the retractable sheath toward the handle. A majority of the length of the pull has a cross sectional shape with a concave side that faces the longitudinal axis and is opposite to a convex side that faces away from the longitudinal axis. The cross sectional shape has a width that is greater than a thickness.
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