公开(公告)号：US20230251258A1

公开(公告)日：2023-08-10

申请号：US18303725

申请日：2023-04-20

Applicant: University of Washington

Inventor： Daniel T. Chiu ,  Chun-Ting Kuo ,  Li Wu

IPC: G01N33/554 ,  B01L3/00 ,  G01N15/14 ,  G01N21/64 ,  G01N33/533

CPC classification number: G01N33/554 ,  B01L3/502715 ,  G01N15/1484 ,  G01N21/6428 ,  G01N21/6452 ,  G01N21/6458 ,  G01N33/533 ,  B01L2300/047 ,  B01L2300/06 ,  B01L2300/0627 ,  B01L2300/0819 ,  B01L2300/0883 ,  B01L2300/18 ,  G01N2021/6432

Abstract: Methods and systems for improved labeling and/or de-labeling a molecule or cell in the context of scientific experimentation, industrial applications, and clinical investigation, including the means to repeat the process of labeling and de-labeling in an efficient manner.

公开(公告)号：US10656073B2

公开(公告)日：2020-05-19

申请号：US16534809

申请日：2019-08-07

Applicant: University of Washington

Inventor： Daniel T. Chiu ,  Chun-Ting Kuo ,  Jiangbo Yu

IPC: G01N33/58 ,  G01N21/25 ,  G01N21/64 ,  G01N15/14 ,  C12Q1/68 ,  C12N13/00 ,  A61K49/00 ,  G01N15/10

Abstract: Methods of optically marking and sorting adherent cells are provided. The methods include providing a plurality of adherent cells attached to a substrate, each adherent cell of the plurality of adherent cells having an optical marker. The methods also include selectively applying light energy to a subset of the plurality of adherent cells, and detaching the plurality of adherent cells from the substrate. These methods also provide the sorting of the plurality of adherent cells.

公开(公告)号：US20200057060A1

公开(公告)日：2020-02-20

申请号：US16347502

申请日：2017-11-16

Applicant: University of Washington

Inventor： Daniel T. Chiu ,  Chun-Ting Kuo ,  Li Wu

IPC: G01N33/554 ,  G01N21/64 ,  G01N15/14 ,  G01N33/533 ,  B01L3/00

Abstract: Methods and systems for improved labeling and/or de-labeling a molecule or cell in the context of scientific experimentation, industrial applications, and clinical investigation, including the means to repeat the process of labeling and de-labeling in an efficient manner.

公开(公告)号：US10429294B2

公开(公告)日：2019-10-01

申请号：US15563121

申请日：2016-04-01

Applicant: University of Washington

Inventor： Daniel T. Chiu ,  Chun-Ting Kuo ,  Jiangbo Yu

IPC: G01N33/58 ,  G01N21/64 ,  G01N21/25 ,  G01N15/14 ,  A61K49/00 ,  C12Q1/68 ,  C12N13/00 ,  G01N15/10

Abstract: Methods of optically marking and sorting adherent cells are provided. The methods include providing a plurality of adherent cells attached to a substrate, each adherent cell of the plurality of adherent cells having an optical marker. The methods also include selectively applying light energy to a subset of the plurality of adherent cells, and detaching the plurality of adherent cells from the substrate. These methods also provide the sorting of the plurality of adherent cells.

公开(公告)号：US11668713B2

公开(公告)日：2023-06-06

申请号：US16347502

申请日：2017-11-16

Applicant: University of Washington

Inventor： Daniel T. Chiu ,  Chun-Ting Kuo ,  Li Wu

IPC: G01N33/554 ,  G01N33/533 ,  B01L3/00 ,  G01N15/14 ,  G01N21/64

CPC classification number: G01N33/554 ,  B01L3/502715 ,  G01N15/1484 ,  G01N21/6428 ,  G01N21/6452 ,  G01N21/6458 ,  G01N33/533 ,  B01L2300/047 ,  B01L2300/06 ,  B01L2300/0627 ,  B01L2300/0819 ,  B01L2300/0883 ,  B01L2300/18 ,  G01N2021/6432

Abstract: Methods and systems for improved labeling and/or de-labeling a molecule or cell in the context of scientific experimentation, industrial applications, and clinical investigation, including the means to repeat the process of labeling and de-labeling in an efficient manner.

公开(公告)号：US20180080863A1

公开(公告)日：2018-03-22

申请号：US15563121

申请日：2016-04-01

Applicant: University of Washington

Inventor： Daniel T. Chiu ,  Chun-Ting Kuo ,  Jiangbo Yu

IPC: G01N15/14 ,  A61K49/00 ,  G01N33/58 ,  G01N21/25 ,  G01N21/64

CPC classification number: G01N15/1475 ,  A61K49/0019 ,  A61K49/0021 ,  C12N13/00 ,  C12Q1/68 ,  G01N15/147 ,  G01N21/25 ,  G01N21/64 ,  G01N33/582 ,  G01N2015/1006 ,  G01N2015/149 ,  G01N2015/1497

Abstract: The present disclosure provides a method of optically marking and sorting adherent cells. In some aspects, the method comprises: providing a plurality of adherent cells attached to a substrate, each adherent cell of the plurality of adherent cells comprising an optical marker; selectively applying light energy to a subset of the plurality of adherent cells; detaching the plurality of adherent cells from the substrate; and sorting the plurality of adherent cells.