公开(公告)号：US20230201744A1

公开(公告)日：2023-06-29

申请号：US18179835

申请日：2023-03-07

Applicant: Waters Technologies Corporation

Inventor： Raymond P. Fisk ,  Timothy J. Becker ,  Mary Elizabeth Lame ,  Frank John Marszaikowski ,  Matthew A. Lauber

IPC: B01D15/38 ,  B01D15/42 ,  B01D15/14 ,  B01D15/12 ,  B01D15/22 ,  B01L3/00

CPC classification number: B01D15/3809 ,  B01D15/424 ,  B01D15/14 ,  B01D15/12 ,  B01D15/22 ,  B01L3/5023 ,  B01L2300/0681 ,  B01L2200/0631 ,  B01L3/5021 ,  B01L2400/0433 ,  B01L2400/0409 ,  B01L2300/069 ,  B01L2200/0668 ,  B01L3/0275

Abstract: The present disclosure pertains to sample preparation devices useful for affinity capture and purification that include one or more internal structures that comprise a reservoir, a well, a fluid passageway, sorbent particles, and a filter element that blocks passage of the affinity sorbent particles, which sample preparation devices combine the attributes of both dispersive and flow through designs into a single sample preparation device. The present disclosure also pertains to kits that contain and methods that use such sample preparation devices.

公开(公告)号：US11998862B2

公开(公告)日：2024-06-04

申请号：US18179835

申请日：2023-03-07

Applicant: Waters Technologies Corporation

Inventor： Raymond P. Fisk ,  Timothy J. Becker ,  Mary Elizabeth Lame ,  Frank John Marszalkowski ,  Matthew A. Lauber

IPC: B01L3/00 ,  B01D15/12 ,  B01D15/14 ,  B01D15/22 ,  B01D15/38 ,  B01D15/42 ,  B01L3/02

CPC classification number: B01D15/3809 ,  B01D15/12 ,  B01D15/14 ,  B01D15/22 ,  B01D15/424 ,  B01L3/5023 ,  B01L3/0275 ,  B01L3/5021 ,  B01L2200/0631 ,  B01L2200/0668 ,  B01L2300/0681 ,  B01L2300/069 ,  B01L2400/0409 ,  B01L2400/0433

Abstract: The present disclosure pertains to sample preparation devices useful for affinity capture and purification that include one or more internal structures that comprise a reservoir, a well, a fluid passageway, sorbent particles, and a filter element that blocks passage of the affinity sorbent particles, which sample preparation devices combine the attributes of both dispersive and flow through designs into a single sample preparation device. The present disclosure also pertains to kits that contain and methods that use such sample preparation devices.

公开(公告)号：US20200284802A1

公开(公告)日：2020-09-10

申请号：US16808233

申请日：2020-03-03

Applicant: Waters Technologies Corporation

Inventor： Moon Chul Jung ,  Mary Elizabeth Lame ,  Caitlin Dunning ,  Christopher John Hughes ,  Xiaoxiao Liu ,  Paula Orens ,  Yun Wang Alelyunas ,  Erin E. Chambers ,  David Dao ,  Robert Birdsall

IPC: G01N33/68 ,  G01N30/72 ,  G01N30/06

Abstract: The present disclosure relates to a method of analyzing a sample comprising a hydrophobic molecule. The method includes preparing an aqueous solution comprising the sample. The method also includes placing the solution in contact with a polypropylene substrate having a deactivated surface that reduces adsorption of the hydrophobic molecule relative to a polypropylene substrate that has not been deactivated. The method also includes analyzing the sample.

公开(公告)号：US20240424427A1

公开(公告)日：2024-12-26

申请号：US18659714

申请日：2024-05-09

Applicant: Waters Technologies Corporation

Inventor： Raymond P. Fisk ,  Timothy J. Becker ,  Mary Elizabeth Lame ,  Frank John Marszalkowski ,  Matthew A. Lauber

IPC: B01D15/38 ,  B01D15/12 ,  B01D15/14 ,  B01D15/22 ,  B01D15/42 ,  B01L3/00 ,  B01L3/02

Abstract: The present disclosure pertains to sample preparation devices useful for affinity capture and purification that include one or more internal structures that comprise a reservoir, a well, a fluid passageway, sorbent particles, and a filter element that blocks passage of the affinity sorbent particles, which sample preparation devices combine the attributes of both dispersive and flow through designs into a single sample preparation device. The present disclosure also pertains to kits that contain and methods that use such sample preparation devices.

公开(公告)号：US11747341B2

公开(公告)日：2023-09-05

申请号：US16808233

申请日：2020-03-03

Applicant: Waters Technologies Corporation

Inventor： Moon Chul Jung ,  Mary Elizabeth Lame ,  Caitlin Dunning ,  Christopher John Hughes ,  Xiaoxiao Liu ,  Paula Orens ,  Yun Wang Alelyunas ,  Erin E. Chambers ,  David Dao ,  Robert Birdsall

IPC: G01N33/68 ,  G01N30/06 ,  G01N30/72

CPC classification number: G01N33/6848 ,  G01N30/06 ,  G01N30/7233

Abstract: The present disclosure relates to a method of analyzing a sample comprising a hydrophobic molecule. The method includes preparing an aqueous solution comprising the sample. The method also includes placing the solution in contact with a polypropylene substrate having a deactivated surface that reduces adsorption of the hydrophobic molecule relative to a polypropylene substrate that has not been deactivated. The method also includes analyzing the sample.

公开(公告)号：US20190134533A1

公开(公告)日：2019-05-09

申请号：US16182401

申请日：2018-11-06

Applicant: WATERS TECHNOLOGIES CORPORATION

Inventor： Timothy J. Becker ,  Frank John Marszalkowski, JR. ,  Matthew A. Lauber ,  Raymond P. Fisk ,  Mary Elizabeth Lame

IPC: B01D15/38 ,  B01D15/42 ,  B01D15/22 ,  B01D15/12 ,  B01D15/14

Abstract: The present disclosure pertains to sample preparation devices useful for affinity capture and purification that include one or more internal structures that comprise a reservoir, a well, a fluid passageway, sorbent particles, and a filter element that blocks passage of the affinity sorbent particles, which sample preparation devices combine the attributes of both dispersive and flow through designs into a single sample preparation device. The present disclosure also pertains to kits that contain and methods that use such sample preparation devices.