ESTABLISHING FLUIDIC CONNECTIONS BETWEEN CHROMATOGRAPHY COMPONENTS

    公开(公告)号:US20220357305A1

    公开(公告)日:2022-11-10

    申请号:US17864944

    申请日:2022-07-14

    Abstract: A thermal module for pre-heating liquid flowing into a liquid chromatography column, includes a trough compartment with two ends, one of the two ends having an electrical socket, a first fluidic assembly, a second fluidic assembly, and a clamp assembly. The clamp assembly includes a rail configured to receive the first fluidic assembly. The clamp assembly includes a carriage slidably mounted to the rail and configured to receive the second fluidic assembly. The carriage is operable to establish a first fluid tight seal between the first fluidic assembly and a chromatography column received within the clamp assembly, and to establish a second fluid tight seal between the second fluidic assembly and the chromatography column. The clamp assembly is disposed within the trough compartment, and the first fluidic assembly is plugged into the electrical socket at the one end of the trough compartment.

    Gasket and Seal Apparatus
    4.
    发明申请
    Gasket and Seal Apparatus 审中-公开
    垫片和密封装置

    公开(公告)号:US20130076029A1

    公开(公告)日:2013-03-28

    申请号:US13626428

    申请日:2012-09-25

    CPC classification number: F16L15/04 F16K27/02 Y10T137/0491

    Abstract: Embodiments of the present invention feature devices and methods for holding fluids at high pressures. One embodiment of the present invention features a fluid containing conveying device for receiving and discharging fluids. The device comprises a housing having a chamber for containing a fluid. The housing has a first gasket receiving surface for receiving a gasket. A gasket formed of a deformable material and having a first abutment surface and second abutment surface. The first abutment surface received on the first gasket receiving surface and the second abutment surface for receiving a chamber closing piece. The chamber closing piece having a second gasket receiving surface, the chamber closing piece for closing the chamber. At least one of the first gasket receiving surface of the housing and the second gasket receiving surface of the chamber closing piece having a retaining grove, having at least one edge. Compression means for compressing the gasket, deforming the material such that the gasket is pressed into retaining groove and gripped by the edge of the cavity to prevent gasket movement.

    Abstract translation: 本发明的实施例的特征在于在高压下保持流体的装置和方法。 本发明的一个实施例的特征在于包含用于接收和排出流体的输送装置。 该装置包括具有用于容纳流体的室的壳体。 壳体具有用于接收垫圈的第一垫片接收表面。 由可变形材料形成并具有第一邻接表面和第二邻接表面的垫圈。 接收在第一垫片接收表面上的第一邻接表面和用于接收室闭合件的第二邻接表面。 所述腔室封闭件具有第二垫片接收表面,所述腔室封闭件用于封闭所述腔室。 壳体的第一垫片接收表面和腔室封闭件的第二垫片接收表面中的至少一个具有保留槽,其具有至少一个边缘。 用于压缩垫圈的压缩装置,使材料变形,使得垫圈被压入保持槽并被空腔的边缘夹持以防止垫圈移动。

    METHOD AND APPARATUS FOR CONTROL OF MASS COMPOSITION OF MOBILE PHASE

    公开(公告)号:US20200088695A1

    公开(公告)日:2020-03-19

    申请号:US16693797

    申请日:2019-11-25

    Abstract: Described are a method and an apparatus for delivering a fluid having a desired mass composition. According to the method, temperatures of the fluids to be mixed are sensed and the densities of the fluids at the sensed temperatures are determined. The volume of each fluid is determined so that a mixture of the fluids at the sensed temperatures has the desired mass composition. The determined volumes of the fluids are combined to create the mixture. In one option, combining the determined volumes includes metering flows of the fluids sequentially into a common fluid channel. Alternatively, combining the determined volumes includes controlling a flow rate of each of the fluids and directing the fluids into a common fluid channel.

    Column heater with active pre-heating

    公开(公告)号:US09714926B2

    公开(公告)日:2017-07-25

    申请号:US15249720

    申请日:2016-08-29

    Abstract: To heat a flowing liquid, an apparatus includes a heater block assembly having a heater block made of thermally conductive material. The heater block assembly has a tube inlet, a tube outlet, and a tube path between the tube inlet and tube outlet. Tubing extends through the tube path from the tube inlet to the tube outlet. The tubing is in thermal communication with the heater block. A heater cartridge, in thermal communication with the heater block, is configured to provide heat to the heater block for transfer to liquid flowing through the tubing between the tube inlet and the tube outlet of the heater block assembly. Circuitry is in electrical communication with the heater cartridge to control a temperature of the heater block by controlling operation of the heater cartridge.

    COLUMN HEATER WITH ACTIVE PRE-HEATING
    9.
    发明申请

    公开(公告)号:US20160363564A1

    公开(公告)日:2016-12-15

    申请号:US15249720

    申请日:2016-08-29

    Abstract: To heat a flowing liquid, an apparatus includes a heater block assembly having a heater block made of thermally conductive material. The heater block assembly has a tube inlet, a tube outlet, and a tube path between the tube inlet and tube outlet. Tubing extends through the tube path from the tube inlet to the tube outlet. The tubing is in thermal communication with the heater block. A heater cartridge, in thermal communication with the heater block, is configured to provide heat to the heater block for transfer to liquid flowing through the tubing between the tube inlet and the tube outlet of the heater block assembly. Circuitry is in electrical communication with the heater cartridge to control a temperature of the heater block by controlling operation of the heater cartridge.

Patent Agency Ranking