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12 条记录 (耗时 0.02 秒)

    Amido-phenyl-.alpha.-D-glucopyranoside derivatives
    3.
    发明授权
    Amido-phenyl-.alpha.-D-glucopyranoside derivatives 失效
    酰氨基 - 苯基-α-D-吡喃葡萄糖苷衍生物

    公开(公告)号：US4536572A

    公开(公告)日：1985-08-20

    申请号：US532676

    申请日：1983-11-02

    申请人： Wan S. Kim ,  Seo Y. Jeong ,  James C. McRea

    发明人： Wan S. Kim ,  Seo Y. Jeong ,  James C. McRea

    IPC分类号： A61K38/00 ,  C07H15/203 ,  C07H15/18

    CPC分类号： C07H15/203 ,  A61K38/00

    摘要： Synthesized succinyl and glutaryl glucosamines, p-(succinylamido)-phenyl-.alpha.-D-gluco- and mannopyranosides, p-(glutarylamido)-phenyl-.alpha.-D-gluco- and mannopyranosides and p-(isothiocyanotophenyl)-.alpha.-D-gluco- and mannopyranosides are reacted with insulin to form corresponding glycosylated insulins containing from 1 to 3 glycosyl groups per insulin molecule. The novel glycosylated insulins resist aggregation and show significant activity in depressing blood sugar levels.

    摘要翻译： 对 - （琥珀酰氨基） - 苯基-α-D-吡喃葡萄糖苷和甘草吡喃糖苷，对 - （戊二酰氨基） - 苯基-α-D-吡喃葡萄糖苷和甘露糖吡喃糖苷和对 - （异硫代氰基苯基）-α- 葡萄糖和甘露糖苷与胰岛素反应形成相应的糖基化胰岛素，每个胰岛素分子含有1至3个糖基。 新型糖基化胰岛素抵抗聚集，显示抑制血糖水平的显着活性。

    Glycosylated insulin derivatives
    5.
    发明授权
    Glycosylated insulin derivatives 失效
    糖基化胰岛素衍生物

    公开(公告)号：US4478830A

    公开(公告)日：1984-10-23

    申请号：US532917

    申请日：1984-02-06

    申请人： Wan S. Kim ,  Seo Y. Jeong ,  James C. McRea

    发明人： Wan S. Kim ,  Seo Y. Jeong ,  James C. McRea

    IPC分类号： A61K38/00 ,  C07H15/203 ,  A61K37/26

    CPC分类号： C07H15/203 ,  A61K38/00 ,  Y10S514/866

    摘要： Synthesized succinyl and glutaryl glucosamines, p-(succinylamido)-phenyl-.alpha.-D-gluco- and mannopyranosides, p-(glutarylamido)-phenyl-.alpha.-D-gluco- and mannopyranosides and p-(isothiocyanotophenyl)-.alpha.-D-gluco- and mannopyranosides are reacted with insulin to form corresponding glycosylated insulins containing from 1 to 3 glycosyl groups per insulin molecule. The novel glycosylated insulins resist aggregation and show significant activity in depressing blood sugar levels.

    摘要翻译： 对 - （琥珀酰氨基） - 苯基-α-D-吡喃葡萄糖苷和甘草吡喃糖苷，对 - （戊二酰氨基） - 苯基-α-D-吡喃葡萄糖苷和甘露糖吡喃糖苷和对 - （异硫代氰基苯基）-α- 葡萄糖和甘露糖苷与胰岛素反应形成相应的糖基化胰岛素，每个胰岛素分子含有1至3个糖基。 新型糖基化胰岛素抵抗聚集，显示抑制血糖水平的显着活性。

    Glycosylated insulin derivatives
    6.
    发明授权
    Glycosylated insulin derivatives 失效
    糖基化胰岛素衍生物

    公开(公告)号：US4489063A

    公开(公告)日：1984-12-18

    申请号：US532681

    申请日：1984-02-06

    申请人： Wan S. Kim ,  Seo Y. Jeong ,  James C. McRea

    发明人： Wan S. Kim ,  Seo Y. Jeong ,  James C. McRea

    IPC分类号： A61K38/00 ,  C07H15/203 ,  A61K37/26

    CPC分类号： C07H15/203 ,  A61K38/00 ,  Y10S514/866

    摘要： Synthesized succinyl and glutaryl glucosamines, p-(succinylamido)- phenyl-.alpha.-D-gluco- and mannopyranosides, p-(glutarylamido)-phenyl-.alpha.-D-gluco- and mannopyranosides and p-(isothiocyanotophenyl)-.alpha.-D-gluco- and mannopyranosides are reacted with insulin to form corresponding glycosylated insulins containing from 1 to 3 glycosyl groups per insulin molecule. The novel glycosylated insulins resist aggregation and show significant activity in depressing blood sugar levels.

    摘要翻译： 对 - （琥珀酰氨基） - 苯基-α-D-吡喃葡萄糖苷和甘草吡喃糖苷，对 - （戊二酰氨基） - 苯基-α-D-吡喃葡萄糖苷和甘露糖吡喃糖苷和对 - （异硫代氰基苯基）-α- 葡萄糖和甘露糖苷与胰岛素反应形成相应的糖基化胰岛素，每个胰岛素分子含有1至3个糖基。 新型糖基化胰岛素抵抗聚集，显示抑制血糖水平的显着活性。

    Control switch
    8.
    发明授权
    Control switch 失效
    控制开关

    公开(公告)号：US5216894A

    公开(公告)日：1993-06-08

    申请号：US959362

    申请日：1992-10-13

    申请人： Wan S. Kim

    发明人： Wan S. Kim

    IPC分类号： F24F11/02 ,  F25B49/00 ,  H01H9/20 ,  H01H35/32

    CPC分类号： F24F11/02 ,  F25B49/005 ,  H01H35/32 ,  H01H9/20 ,  F25B2500/222

    摘要： A control switch comprises a bellow which contracts and expands pressure of the refrigerant, a lock/unlock member which cooperates with the existence of the pressure of the refrigerant, a spring for forcing the lock/unlock member against the pressure of the bellow, and a rotatable shaft operatively disposed through the lock/unlock member. The lock/unlock member has an unlock slot proximate the bellow, a lock slot distal the bellow, and a tapered transition portion between the unlock slot and the lock slot. The shaft is a polygonal, e.g. hexagonal, which fits into the lock slot when the pressure of the refrigerant is under a predetermined value. The user is made aware of the leakage of the refrigerant by the restriction of the rotation of shaft or a break in the power circuit, or both. This prevents the operation of an inefficient in the air conditioner.

    摘要翻译： 控制开关包括收缩和膨胀制冷剂的压力的波纹管，与制冷剂的压力的存在配合的锁定/解锁构件，用于迫使锁定/解锁构件抵抗波纹管的压力的弹簧，以及 可动轴可操作地设置穿过锁/解锁构件。 锁/解锁构件具有靠近波纹管的解锁槽，远离波纹管的锁槽和解锁槽和锁槽之间的锥形过渡部分。 轴是多边形，例如 六边形，当制冷剂的压力低于预定值时装配到锁槽中。 使用者通过限制轴的旋转或电源电路中断或两者来了解制冷剂的泄漏。 这防止了空调器的低效率的操作。