公开(公告)号：US06942837B2

公开(公告)日：2005-09-13

申请号：US09848270

申请日：2001-05-04

申请人： Ward Kevin Frye ,  Jacob Koppel Freudenthal ,  Terri Christina Labelle ,  Eugene Young

发明人： Ward Kevin Frye ,  Jacob Koppel Freudenthal ,  Terri Christina Labelle ,  Eugene Young

IPC分类号： G01N31/20 ,  B01J4/00 ,  B01L3/00 ,  B01L3/02 ,  C12M1/00 ,  C12N15/09 ,  C12Q1/68 ,  G01N1/00 ,  G01N35/00 ,  G01N35/02 ,  G01N35/10 ,  G01N37/00 ,  C12M1/34

CPC分类号： B01L3/50853 ,  B01L3/0203 ,  B01L2200/025 ,  B01L2200/0642 ,  B01L2200/141 ,  B01L2300/046 ,  B01L2300/047 ,  B01L2300/049 ,  B01L2300/0829 ,  B01L2300/0864 ,  B01L2400/049 ,  B01L2400/0633 ,  G01N1/14 ,  G01N35/00 ,  G01N35/028 ,  G01N35/1097 ,  G01N2035/00148 ,  G01N2035/1037

摘要： A system for filling a substrate having at least one chamber with a liquid sample is provided. The system in one embodiment includes a substrate defining a network of passageways including at least one chamber for the liquid sample, and an adapter. The adapter includes a fill reservoir for the liquid sample, a vacuum port for attachment to a vacuum source, and at least two channels. One channel allows a vacuum to be imparted to the network, and the other channel allows the liquid sample to be introduced into the network. The system also includes a mechanism that sequentially closes and opens at least one of the channels so that a vacuum can first be introduced to the substrate and thereafter the liquid sample introduced to the substrate for permitting the vacuum to urge the liquid sample to flow from the fill reservoir into the substrate. An apparatus for positioning a substrate with a plurality of sample detection chambers in a detection unit is also provided.

摘要翻译： 提供了一种用于用液体样品填充具有至少一个室的基板的系统。 在一个实施例中的系统包括限定通道网络的基板，包括用于液体样品的至少一个室和适配器。 适配器包括用于液体样品的填充容器，用于附接到真空源的真空端口和至少两个通道。 一个通道允许将真空赋予网络，另一个通道允许将液体样品引入网络。 该系统还包括依次关闭和打开至少一个通道的机构，使得可以首先将真空引入衬底，然后将引入到衬底中的液体样品引入真空以迫使液体样品从 将储存器填充到基板中。 还提供了一种用于将具有多个样本检测室的基板定位在检测单元中的装置。