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    Adjustable local oscillator path in a communication device with a transmitter
    3.
    发明授权
    Adjustable local oscillator path in a communication device with a transmitter 有权
    具有发射机的通信设备中的可调本地振荡器路径

    公开(公告)号：US08472890B2

    公开(公告)日：2013-06-25

    申请号：US11947597

    申请日：2007-11-29

    申请人： Wei Zhuo ,  Aristotele Hadjichristos ,  Tzu-wang Pan

    发明人： Wei Zhuo ,  Aristotele Hadjichristos ,  Tzu-wang Pan

    IPC分类号： H04B1/40

    CPC分类号： H04B1/109 ,  H04B1/525

    摘要： A communication device includes a transmitter and a receiver. The receiver mixes a local oscillator (LO) signal with the received signal to downconvert the received signal to an intermediate frequency (IF). The LO path that feeds the LO signal to the downconverting mixer is controlled based on the transmit power of the transmitter. For high transmit power, the drive of the LO path is increased, thereby increasing the signal-to-noise ratio of the LO signal input into the mixer. For low transmit power levels, the drive to the LO path is decreased, reducing power consumption in the communication device. In this way, receiver path noise due to mixing of the LO phase noise with the self-generated transmitter signal is selectively controlled while incurring lower power consumption penalty. The communication device may be an access terminal configured for communication with a cellular radio network.

    摘要翻译： 通信设备包括发射机和接收机。 接收器将本地振荡器（LO）信号与接收到的信号混合，以将接收到的信号下变频到中频（IF）。 基于发射机的发射功率来控制将LO信号馈送到下变频混频器的LO路径。 对于高发射功率，LO路径的驱动增加，从而增加输入混频器的LO信号的信噪比。 对于低发射功率电平，降低LO路径的驱动，从而降低通信设备的功耗。 以这种方式，由于LO相位噪声与自发送发射机信号的混合引起的接收机路径噪声被选择性地控制，同时产生较低的功耗损失。 通信设备可以是被配置为与蜂窝无线电网络进行通信的接入终端。

    ADJUSTABLE LOCAL OSCILLATOR PATH IN A COMMUNICATION DEVICE WITH A TRANSMITTER
    4.
    发明申请
    ADJUSTABLE LOCAL OSCILLATOR PATH IN A COMMUNICATION DEVICE WITH A TRANSMITTER 有权
    在具有发射机的通信设备中可调谐的本地振荡器路径

    公开(公告)号：US20090130994A1

    公开(公告)日：2009-05-21

    申请号：US11947597

    申请日：2007-11-29

    申请人： Wei Zhuo ,  Aristotele Hadjichristos ,  Tzu-wang Pan

    发明人： Wei Zhuo ,  Aristotele Hadjichristos ,  Tzu-wang Pan

    IPC分类号： H04B1/40 ,  H04B1/04

    CPC分类号： H04B1/109 ,  H04B1/525

    摘要： A communication device includes a transmitter and a receiver. The receiver mixes a local oscillator (LO) signal with the received signal to downconvert the received signal to an intermediate frequency (IF). The LO path that feeds the LO signal to the downconverting mixer is controlled based on the transmit power of the transmitter. For high transmit power, the drive of the LO path is increased, thereby increasing the signal-to-noise ratio of the LO signal input into the mixer. For low transmit power levels, the drive to the LO path is decreased, reducing power consumption in the communication device. In this way, receiver path noise due to mixing of the LO phase noise with the self-generated transmitter signal is selectively controlled while incurring lower power consumption penalty. The communication device may be an access terminal configured for communication with a cellular radio network.

    摘要翻译： 通信设备包括发射机和接收机。 接收器将本地振荡器（LO）信号与接收到的信号混合，以将接收到的信号下变频到中频（IF）。 基于发射机的发射功率来控制将LO信号馈送到下变频混频器的LO路径。 对于高发射功率，LO路径的驱动增加，从而增加输入混频器的LO信号的信噪比。 对于低发射功率电平，降低LO路径的驱动，从而降低通信设备的功耗。 以这种方式，由于LO相位噪声与自发送发射机信号的混合引起的接收机路径噪声被选择性地控制，同时产生较低的功耗损失。 通信设备可以是被配置为与蜂窝无线电网络进行通信的接入终端。

    Offset correction for passive mixers
    5.
    发明授权
    Offset correction for passive mixers 有权
    无源混频器的偏移校正

    公开(公告)号：US08045944B2

    公开(公告)日：2011-10-25

    申请号：US11864310

    申请日：2007-09-28

    申请人： Wei Zhuo ,  Roger Brockenbrough ,  Solti Peng

    发明人： Wei Zhuo ,  Roger Brockenbrough ,  Solti Peng

    IPC分类号： H04B1/10 ,  G05F1/10

    CPC分类号： H03D7/1441 ,  H03D7/1458 ,  H03D7/1466 ,  H03D2200/0043 ,  H03D2200/0047

    摘要： A downconversion mixer includes a configurable gate or bulk bias voltage to allow calibration and correction of device offsets. Calibration may be performed on the configurable bias voltages to minimize IM2 distortion in the mixer. The techniques have minimal impact on voltage headroom, impose no requirement for a signal path to be phase-matched with a calibration path, and are particularly well-suited for passive mixers.

    摘要翻译： 下变频混频器包括可配置的栅极或体偏置电压，以允许校准和校正器件偏移。 可以对可配置的偏置电压进行校准，以最小化混频器中的IM2失真。 这些技术对电压净空的影响最小，不要求将信号路径与校准路径进行相位匹配，特别适用于被动混频器。

    OFFSET CORRECTION FOR PASSIVE MIXERS
    8.
    发明申请
    OFFSET CORRECTION FOR PASSIVE MIXERS 有权
    被动混合器的偏差校正

    公开(公告)号：US20090075622A1

    公开(公告)日：2009-03-19

    申请号：US11864310

    申请日：2007-09-28

    申请人： Wei Zhuo ,  Roger Brockenbrough ,  Solti Peng

    发明人： Wei Zhuo ,  Roger Brockenbrough ,  Solti Peng

    IPC分类号： H04B1/28

    CPC分类号： H03D7/1441 ,  H03D7/1458 ,  H03D7/1466 ,  H03D2200/0043 ,  H03D2200/0047

    摘要： A downconversion mixer includes a configurable gate or bulk bias voltage to allow calibration and correction of device offsets. Calibration may be performed on the configurable bias voltages to minimize IM2 distortion in the mixer. The techniques have minimal impact on voltage headroom, impose no requirement for a signal path to be phase-matched with a calibration path, and are particularly well-suited for passive mixers.

    摘要翻译： 下变频混频器包括可配置的栅极或体偏置电压，以允许校准和校正器件偏移。 可以对可配置的偏置电压进行校准，以最小化混频器中的IM2失真。 这些技术对电压净空的影响最小，不要求将信号路径与校准路径进行相位匹配，特别适用于被动混频器。

    USE OF NUCLEOLIN AS A BIOMARKER FOR LYMPHANGIOGENESIS IN CANCER PROGNOSIS AND THERAPY
    10.
    发明申请
    USE OF NUCLEOLIN AS A BIOMARKER FOR LYMPHANGIOGENESIS IN CANCER PROGNOSIS AND THERAPY 审中-公开
    作为生物标记物的核蛋白用于癌症预防和治疗中的淋巴细胞生成

    公开(公告)号：US20130023479A1

    公开(公告)日：2013-01-24

    申请号：US13554913

    申请日：2012-07-20

    申请人： Yongzhang Luo ,  Wei Zhuo ,  Yan Fu ,  Guodong Chang

    发明人： Yongzhang Luo ,  Wei Zhuo ,  Yan Fu ,  Guodong Chang

    IPC分类号： G01N33/574 ,  A61K38/17 ,  A61P35/04 ,  C40B30/04

    CPC分类号： G01N33/574 ,  A61K38/39 ,  C07K16/28 ,  C07K2317/76 ,  G01N2333/515 ,  G01N2800/52 ,  G01N2800/56 ,  G01N2800/7014

    摘要： The present invention relates to a method of identifying cancer subjects, in particular human patients, who are suitable for anti-lymphangiogenesis therapy to prevent tumor growth and tumor metastasis. The present invention also relates to a new approach, which uses nucleolin as a bait to search and screen for lymphangiogenesis inhibitors or cancer suppressors, which function in a manner that is analogous to endostatin. The invention is based upon the discovery that nucleolin is specifically expressed on lymphangiogenic vessels and functions as a specific receptor for endostatin, and thus is involved in the signal transduction pathway of endostatin as an anti-lymphangiogenesis inhibitor. The present invention also discloses that cell surface nucleolin on lymphatic endothelial cells is a biomarker for lymphangiogenic vessels, which could be used for the prediction of tumor metastasis.

    摘要翻译： 本发明涉及鉴定适合于抗淋巴管生成治疗以预防肿瘤生长和肿瘤转移的癌症受试者，特别是人类患者的方法。 本发明还涉及使用核仁林作为诱饵来搜索和筛选淋巴管生成抑制剂或癌抑制因子的新方法，其以类似于内皮抑素的方式起作用。 本发明基于以下发现：核仁林在淋巴管生成血管上特异性表达，并且作为内皮抑制素的特异性受体起作用，因此参与作为抗淋巴管生成抑制剂的内皮抑素的信号转导途径。 本发明还公开了淋巴管内皮细胞上的细胞表面核仁素是淋巴管生成血管生物标志物，可用于预测肿瘤转移。