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    Microbicidal active ingredients
    4.
    发明授权
    Microbicidal active ingredients 失效
    杀菌活性成分

    公开(公告)号：US06346260B1

    公开(公告)日：2002-02-12

    申请号：US09629416

    申请日：2000-08-01

    申请人： Werner Hölzl ,  Wolfgang Haap ,  Dietmar Ochs ,  Karin Puchtler ,  Marcel Schnyder

    发明人： Werner Hölzl ,  Wolfgang Haap ,  Dietmar Ochs ,  Karin Puchtler ,  Marcel Schnyder

    IPC分类号： A01N4340

    CPC分类号： A01N43/10 ,  A01N35/04 ,  A01N37/42 ,  A01N43/40

    摘要： The use of hydroxyphenyl-1,3-propanediones of formula: wherein R1 and R2 are each independently of the other hydrogen, C1-C12alkyl, C1-C12alkoxy, trifluoro-C1-C3alkyl, phenyl or halogen; R3 is a 5- or 6-membered heteroaromatic radical; thiophenyl; or a radical of formula: R4, R5, R6 and R7 are each independently of the other hydrogen, halogen, C1-C12alkyl, C1-C12alkoxy, carboxy or trifluoro-C1-C3alkyl; in the antimicrobial treatment of surfaces, is described. The compounds exhibit a pronounced action against pathogenic gram-positive and gram-negative bacteria, and also against yeasts and molds.

    摘要翻译： 使用下式的羟基苯基-1,3-丙二酮：其中R 1和R 2各自独立于另一个氢，C 1 -C 12烷基，C 1 -C 12烷氧基，三氟-C 1 -C 3烷基，苯基或卤素; R 3是5-或6- 元杂芳基; 噻吩基; 或者式R 4，R 5，R 6和R 7基团各自独立地为氢，卤素，C 1 -C 12烷基，C 1 -C 12烷氧基，羧基或三氟-C 1 -C 3烷基;在表面的抗微生物处理中。 化合物表现出对病原性革兰氏阳性和革兰氏阴性细菌以及酵母和霉菌的显着作用。

    Hydroxyphenylvinylthiazoles
    5.
    发明授权
    Hydroxyphenylvinylthiazoles 失效
    羟基苯基乙烯基噻唑

    公开(公告)号：US06624182B1

    公开(公告)日：2003-09-23

    申请号：US09714716

    申请日：2000-11-16

    申请人： Wolfgang Haap ,  Werner Hölzl ,  Dietmar Ochs ,  Karin Puchtler ,  Marcel Schnyder

    发明人： Wolfgang Haap ,  Werner Hölzl ,  Dietmar Ochs ,  Karin Puchtler ,  Marcel Schnyder

    IPC分类号： A61K31425

    CPC分类号： C07D277/22 ,  A01N43/78 ,  C07D277/24

    摘要： The use of hydroxyphenylvinylthiazoles of formula wherein R1, R2, R3 and R4 are each independently of the others hydrogen; halogen; hydroxy, C1-C16-alkyl, C1-C16alkoxy, phenyl; phenyl-C1-C3alkyl; C6-C10aryloxy, amino, mono-C1-C5alkyl-amino, di-C1-C5alkylamino or -NO2; wherein at least one of the radicals R1, R2, R3 and R4 is hydroxy; R5 is C1-C5alkyl; C1-C5alkoxy; or unsubstituted or halo-, C1-C5alkyl-, C1-C5alkoxy-, hydroxy- or pyrrolidinyl-substituted phenyl; as microbicidal active ingredients is described. The compounds exhibit a pronounced action against pathogenic gram-positive and gram-negative bacteria, and also against yeasts and moulds. Accordingly, they are suitable for the antimicrobial treatment, especially the preservation and disinfection, of surfaces.

    摘要翻译： 使用羟基苯基乙烯基噻唑的化合物R1，R2，R3和R4各自独立地为氢; 卤素; 羟基，C 1 -C 16 - 烷基，C 1 -C 16烷氧基，苯基; 苯基-C 1 -C 3烷基; C 1 -C 10芳氧基，氨基，单-C 1 -C 5烷基 - 氨基，二-C 1 -C 5烷基氨基或-NO 2; 其中基团R 1，R 2，R 3和R 4中的至少一个是羟基; R 5是C 1 -C 5烷基; C1-C5烷氧基; 或未取代或卤代 - ，C 1 -C 5烷基 - ，C 1 -C 5烷氧基 - ，羟基 - 或吡咯烷基 - 取代的苯基; 作为杀微生物活性成分被描述。 该化合物对病原性革兰氏阳性和革兰氏阴性细菌以及酵母和霉菌都表现出明显的作用。 因此，它们适用于抗菌处理，特别是表面的保存和消毒。

    4-aminobut-2-ynecarboxylic acid derivatives
    7.
    发明授权
    4-aminobut-2-ynecarboxylic acid derivatives 失效
    4-氨基丁-2-炔酸衍生物

    公开(公告)号：US06743940B2

    公开(公告)日：2004-06-01

    申请号：US10016542

    申请日：2001-12-13

    申请人： Werner Hölzl ,  Wolfgang Haap ,  Jürgen Koppold ,  Dietmar Ochs ,  Karin Petzold ,  Marcel Schnyder

    发明人： Werner Hölzl ,  Wolfgang Haap ,  Jürgen Koppold ,  Dietmar Ochs ,  Karin Petzold ,  Marcel Schnyder

    IPC分类号： C07C22900

    CPC分类号： C07C229/30

    摘要： There are described 4-aminobut-2-ynecarboxylic acid derivatives of formula wherein R1 and R2 are each independently of the other hydrogen, C1-C20alkyl; C3-C12cycloalkyl; unsubstituted or C1-C5alkyl-, C3-C12cycloalkyl-, C1-C5alkoxy-, C3-C12cycloalkoxy-, halo-, oxo-, carboxy-, carboxy-C1-C7alkyl ester-, carboxy-C3-C12cycloalkyl ester-, cyano-, trifluoromethyl-, pentafluoroethyl-, amino-, N,N-mono- or di-C1-C20alkylamino- or nitro-substituted phenyl, phenyl-C1-C5alkyl, naphthyl and naphthyl-C1-C5alkyl; and R3 is C1-C20alkyl; C3-C12cycloalkyl. The compounds exhibit a pronounced activity against gram-positive and gram-negative bacteria, and also against yeasts and moulds.

    摘要翻译： 描述了通式为R 1的4-氨基丁-2-炔酸衍生物，R 2各自独立地为氢，C 1 -C 20烷基; C 3 -C 12环烷基; 未取代的或C 1 -C 5烷基 - ，C 3 -C 12环烷基 - ，C 1 -C 5烷氧基 - ，C 3 -C 12环烷氧基 - ，卤代 - ，氧代 - ，羧基 - ，羧基-C 1 -C 7烷基酯 - ，羧基-C 3 -C 12环烷基酯 - 氰基 - 三氟甲基 - ，五氟乙基 - ，氨基 - ，N，N-单或二-C 1 -C 20烷基氨基或硝基取代的苯基，苯基-C 1 -C 5烷基，萘基和萘基-C 1 -C 5烷基; 和R 3是C 1 -C 20烷基; C3-C12环烷基。化合物对革兰氏阳性和革兰氏阴性细菌以及酵母和霉菌都表现出明显的活性。

    Use of phenylethylamine derivatives for the antimicrobial treatment of surfaces
    8.
    发明授权
    Use of phenylethylamine derivatives for the antimicrobial treatment of surfaces 失效
    苯乙胺衍生物用于表面抗微生物处理

    公开(公告)号：US06846492B2

    公开(公告)日：2005-01-25

    申请号：US10204520

    申请日：2001-02-13

    申请人： Wolfgang Haap ,  Werner Hölzl ,  Dietmar Ochs ,  Karin Petzold ,  Marcel Schnyder

    发明人： Wolfgang Haap ,  Werner Hölzl ,  Dietmar Ochs ,  Karin Petzold ,  Marcel Schnyder

    IPC分类号： A01N33/10 ,  A01N37/38 ,  A01N39/00 ,  A01N39/02 ,  A01N39/04 ,  C07C217/60 ,  C07C255/54 ,  A01N25/00 ,  A61K7/075 ,  A61K7/50 ,  C11D7/00 ,  D06L1/00

    CPC分类号： C07C255/54 ,  A01N33/10 ,  A01N37/38 ,  A01N39/00 ,  A01N39/02 ,  A01N39/04 ,  C07C217/60 ,  C07C2601/08

    摘要： The use of compounds of formula (1) is described, in which compounds R1, R2 and R3 are each independently of the others hydrogen; C1-C20alkyl; C3-C7cycloalkyl; C2-C20alkenyl; C4-C7cycloalkenyl; C2-C20alkynyl, C4-C7cycloalkynyl; or unsubstituted or C1-C5alkyl-, C3-C7cylcoalkyl-, C1-C5alkoxyl-, C3-C7cycloakoxy-, halo-, oxo-, carboxy-, carboxy-C1-C7alkyl ester-, carboxy-C3-C7cylcloalkyl ester-, cyano-, trifluoromethyl-, pentafluoroethyl-, amino-, N,N-mono- or di-C1-C20alkylamino- or nitro-substituted phenyl-C1-C5alkyl, naphthyl-C1-C5alkyl, phenylcarbonyl-C1-C5alkyl, naphthylcarbonyl-C1-C5alkyl, pyrrolylalkyl, furanylalkyl, thiophenylalkyl, pyrazolylalkyl, imidazolylalkyl, oxazolylalkyl, thiazolylalkyl, isoxazolylalkyl, isothiazolylalkyl, 1,2,3-triazolylalkyl, 1,2,4-triazolylalkyl, 1,2,3-oxadiazolylalkyl, 1,3,4-oxadiazolylalkyl, 1,2,3-thiadiazolylalkyl, 1,3,4-thiadiazolylalkyl, indolylalkyl, pyridylalkyl, pyridazinylalkyl, pyrimidinylalkyl, pyridazinylalkyl, quinolinylalkyl, isoquinolinylalkyl, pyrrolyl, furanyl, thiophenyl, pyrazolyl, imidazolyl, oxazolyl, thiazolyl, isoxazolyl, isothiazolyl, 1,2,3-triazolyl, 1,2,4-triazolyl, 1,2,3-oxadiazolyl, 1,3,4-oxadiazolyl, 1,2,3-thiadiazolyl, 1,3,4-thiadiazolyl, indolyl, pyridyl, pyridazinyl, pyrimidinyl, pyridazinyl, quinolinyl or isoquinolinyl; R4, R5, R6 and R7 are each independently of the others hydrogen; C1-C20alkyl; C3-C7 cycloalky; C2-C20alkenyl; C4-C7 cycloalkenyl; C2-C20alkynyl; or C4-C7 cycloalkynyl; and m and n are each independently of the other 0 or 1, for antimicrobial treatment of surfaces. The compounds exhibit a pronounced activity against pathogenic gram-positive and gram-negative bacteria, and also against yeasts and moulds. They are accordingly suitable for the antimicrobial treatment, especially preservation and disinfection, of surfaces.

    摘要翻译： 描述了式（1）化合物的用途，其中化合物R1，R2和R3各自独立地为氢; C1-C20烷基; C 3 -C 7环烷基; C2-C20烯基; C4-C7环烯基; C 2 -C 20炔基，C 4 -C 7环炔基; 或未取代的或C 1 -C 5烷基 - ，C 3 -C 7烷基烷基 - ，C 1 -C 5烷氧基 - ，C 3 -C 7环烷氧基 - ，卤代 - ，氧代 - ，羧基 - ，羧基-C 1 -C 7烷基酯 - ，羧基-C 3 -C 7环烷基酯 - 氰基 - 三氟甲基 - ，五氟乙基 - ，氨基 - ，N，N-单或二-C 1 -C 20烷基氨基或硝基取代的苯基-C 1 -C 5烷基，萘基-C 1 -C 5烷基，苯基羰基-C 1 -C 5烷基，萘基羰基-C 1 -C 5烷基 ，吡咯基烷基，呋喃基烷基，噻吩基烷基，吡唑基烷基，咪唑基烷基，恶唑基烷基，噻唑基烷基，异恶唑基烷基，异噻唑基烷基，1,2,3-三唑基烷基，1,2,4-三唑基烷基，1,2,3-恶二唑基烷基，1,3,4-恶二唑基烷基 1,2,3-噻二唑基烷基，1,3,4-噻二唑基烷基，吲哚基烷基，吡啶基烷基，哒嗪基烷基，嘧啶基烷基，哒嗪基烷基，喹啉基烷基，异喹啉基烷基，吡咯基，呋喃基，噻吩基，吡唑基，咪唑基，恶唑基，噻唑基，异恶唑基，异噻唑基， ，2,3-三唑基，1,2,4-三唑基，1,2,3-恶二唑基，1,3,4-恶二唑基，1,2,3-噻二唑基，1,3,4-噻二唑基，吲哚基， 吡啶基，哒嗪基，嘧啶基，哒嗪基，喹啉基或异喹啉基; R4，R5，R6和R7各自独立地为氢; C1-C20烷基; C3-C7环烷基; C2-C20烯基; C4-C7环烯基; C2-C20炔基; 或C 4 -C 7环炔基; m和n各自独立地为0或1，用于表面的抗微生物处理。 该化合物显示出对病原性革兰氏阳性的显着活性

    Silanyl phenols and naphthols
    10.
    发明授权
    Silanyl phenols and naphthols 失效

    公开(公告)号：US07078550B2

    公开(公告)日：2006-07-18

    申请号：US10466460

    申请日：2002-01-10

    申请人： Werner Hölzl ,  Wolfgang Haap ,  Jürgen Koppold

    发明人： Werner Hölzl ,  Wolfgang Haap ,  Jürgen Koppold

    IPC分类号： C07F7/04

    CPC分类号： C07F7/0838 ,  C07F7/081

    摘要： There are described silanyl phenols and naphthols of formula (1a) or (1b), wherein R1 is hydrogen; halogen; hydroxy; C1–C20alkyl; C3–C12cycloalkyl; C1–C20alkoxy; trifluoromethyl; pentafluoroethyl; mono- or di-C1–C5alkylamino; hydroxy-C1–C5alkyl; or phenyl, phenyl-C1–C20alkyl, phenoxy, phenyl-C1–C20alkoxy, naphthyl or naphthyl-C1–C20alkyl each unsubstituted or substituted by C1–C5alkyl, C3–C12cycloalkyl, C1–C5alkoxy, C3–C12cycloalkoxy, halogen, oxo, carboxy, carboxy-C1–C7alkyl ester, carboxy-C3–C12cycloalkyl ester, cyano, trifluoromethyl, pentafluoroethyl, amino, N,N-mono- or di-C1–C20alkylamino or by nitro; R2, R3 and R4 are each independently of the others hydrogen; C1–C20alkyl; or C3–C12-cycloalkyl; R5, R6 and R7 are each independently of the others C1–C20alkyl, C5–C10aryl, C1–C20alkoxy, phenyl-C1–C20alkyl, phenyl-C1–C20alkoxy, C2–C5alkenyl, —O—Si—(C1–C5alkyl)3; or O—Si—(C1–C5alkyl)2-O—Si(C1–C5alkyl)3 and n is 0 or 1. The compounds exhibit a pronounced activity against Gram positive and Gram negative bacteria, and also against yeasts and moulds