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公开(公告)号：US07849850B2
公开(公告)日：2010-12-14
申请号：US10375957
申请日：2003-02-28
申请人： William G. Atterbury , Chad E. Bouton , David R. Busick , James E. Dvorsky , Peter A. Gaydos , David A. Holley , Daniel D. Meek , Gregory A. Trees
发明人： William G. Atterbury , Chad E. Bouton , David R. Busick , James E. Dvorsky , Peter A. Gaydos , David A. Holley , Daniel D. Meek , Gregory A. Trees
CPC分类号： A61M15/02 , A61M11/001 , B05B1/18 , B05B5/025 , B05B5/03 , B05B5/0533 , B05B5/1691
摘要： An improved Electrohydrodynamic (EHD) nozzle particularly suitable for a handheld pulmonary aerosol inhaler increases the consistent and efficient dispensing of therapeutic liquids by reducing or eliminating wetting through shielding of discharge electrodes. Some versions further eliminate wetting while enhances neutralization of the aerosol through presentation of a corona wind of ions annularly surround the aerosol. Incorporation of improved liquid distribution with consistent pressure drops to each EHD nozzle tip allows horizontal dispensing, and by using dielectric nozzle tips with low surface energy to thereby avoid wicking between dispenses and to advantageously reduce achievable particle size when dispensing. Some versions feature enhanced snap-fit assembly and other manufacturability advantages. One of the unique features of the EHD nozzles is achieved high dose rate (microliters/minute) with low wetting and small particle size (1.0-5 microns), although these properties tend to be mutually exclusive. Furthermore, these attributes are incorporated into a conveniently small, handheld device.
摘要翻译： 特别适用于手持式肺气溶胶吸入器的改进的电动力学（EHD）喷嘴通过减少或消除通过屏蔽放电电极的润湿来增加治疗液体的一致和有效的分配。 一些版本进一步消除了润湿，同时通过环绕环绕气溶胶的离子的电晕放电来增强气溶胶的中和。 将具有一致的压降的改进的液体分布结合到每个EHD喷嘴尖端允许水平分配，并且通过使用具有低表面能的介电喷嘴尖端，从而避免分配之间的芯吸，并且有利地减少分配时可实现的粒度。 某些版本具有增强的卡扣配合和其他可制造性优势。 EHD喷嘴的独特特征之一是实现高剂量率（微升/分钟），具有低润湿和小粒径（1.0-5微米），尽管这些性质倾向于相互排斥。 此外，这些属性被并入到便利的小型手持设备中。
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公开(公告)号：US20080308580A1
公开(公告)日：2008-12-18
申请号：US11560540
申请日：2006-11-16
IPC分类号： B65D88/54
CPC分类号： A61M5/31525 , A61M5/14566 , A61M5/20 , A61M5/31556 , A61M5/31573 , A61M11/00 , A61M11/001 , A61M15/0065 , A61M2005/1402 , A61M2005/14264 , A61M2005/14506 , A61M2005/3128 , A61M2005/31588 , A61M2202/04 , A61M2205/106 , A61M2205/128 , A61M2205/3306 , A61M2205/3372 , A61M2205/3375 , A61M2205/50 , A61M2205/702 , A61M2205/8206 , B05C17/0103 , G01F11/029
摘要： The present invention is directed to metering devices, systems, and methods that mitigate differential thermal expansion/contraction for the efficient, accurate, and reproducible metered delivery of fluids. The present invention allows the net fluid volume and a plunger location within a fluid dispensing container to automatically adjust under the influence of differential thermal expansion/contraction between the fluid and the fluid dispensing container that the fluid is contained within. Further, the present invention allows the metering system drive to sense the adjusted plunger location and allows the metering system drive to re-zero itself to produce an accurate volumetric delivery of fluid from the fluid dispensing container. The metering system includes means for controlling the travel of the metering system drive, and hence the travel of the plunger into the fluid dispensing container, for delivering accurate/precise amounts of the fluid from the fluid dispensing container. The metering system may also mitigate dead volume in the metering system.
摘要翻译： 本发明涉及用于减少不同热膨胀/收缩的计量装置，系统和方法，用于有效，精确和可再现的计量输送流体。 本发明允许流体分配容器内的净流体体积和柱塞位置在流体和流体分配容器之间的不同热膨胀/收缩的影响下自动调节，流体分配容器内部包含有流体。 此外，本发明允许计量系统驱动器感测经调节的柱塞位置，并且允许计量系统驱动器自身重新定位以产生来自流体分配容器的流体的精确的体积输送。 计量系统包括用于控制计量系统驱动器的行程以及因此柱塞进入流体分配容器的行程的装置，用于从流体分配容器输送精确/精确量的流体。 计量系统还可以减轻计量系统中的死体积。
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公开(公告)号：USD610684S1
公开(公告)日：2010-02-23
申请号：US29334739
申请日：2009-03-31
申请人： Peter A. Gaydos
设计人： Peter A. Gaydos
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公开(公告)号：US07959609B2
公开(公告)日：2011-06-14
申请号：US11560540
申请日：2006-11-16
IPC分类号： A61M37/00
CPC分类号： A61M5/31525 , A61M5/14566 , A61M5/20 , A61M5/31556 , A61M5/31573 , A61M11/00 , A61M11/001 , A61M15/0065 , A61M2005/1402 , A61M2005/14264 , A61M2005/14506 , A61M2005/3128 , A61M2005/31588 , A61M2202/04 , A61M2205/106 , A61M2205/128 , A61M2205/3306 , A61M2205/3372 , A61M2205/3375 , A61M2205/50 , A61M2205/702 , A61M2205/8206 , B05C17/0103 , G01F11/029
摘要： The present invention is directed to metering devices, systems, and methods that mitigate differential thermal expansion/contraction for the efficient, accurate, and reproducible metered delivery of fluids. The present invention allows the net fluid volume and a plunger location within a fluid dispensing container to automatically adjust under the influence of differential thermal expansion/contraction between the fluid and the fluid dispensing container that the fluid is contained within. Further, the present invention allows the metering system drive to sense the adjusted plunger location and allows the metering system drive to re-zero itself to produce an accurate volumetric delivery of fluid from the fluid dispensing container. The metering system includes means for controlling the travel of the metering system drive, and hence the travel of the plunger into the fluid dispensing container, for delivering accurate/precise amounts of the fluid from the fluid dispensing container. The metering system may also mitigate dead volume in the metering system.
摘要翻译： 本发明涉及用于减少不同热膨胀/收缩的计量装置，系统和方法，用于有效，精确和可再现的计量输送流体。 本发明允许流体分配容器内的净流体体积和柱塞位置在流体和流体分配容器之间的不同热膨胀/收缩的影响下自动调节，流体分配容器内部包含有流体。 此外，本发明允许计量系统驱动器感测经调节的柱塞位置，并且允许计量系统驱动器自身重新定位以产生来自流体分配容器的流体的精确的体积输送。 计量系统包括用于控制计量系统驱动器的行程以及因此柱塞进入流体分配容器的行程的装置，用于从流体分配容器输送精确/精确量的流体。 计量系统还可以减轻计量系统中的死体积。
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公开(公告)号：US20100274268A1
公开(公告)日：2010-10-28
申请号：US12429315
申请日：2009-04-24
申请人： ERROL O. SINGH , Peter A. Gaydos
发明人： ERROL O. SINGH , Peter A. Gaydos
IPC分类号： A61B17/122 , A61B17/00
CPC分类号： A61B17/122 , A61B17/1227 , A61B2017/0023 , A61B2017/2808 , A61F2/0054
摘要： A squeeze-to-set medical clamp having a first unset position and a second set position is disclosed. The clamp generally includes a primary arm, a secondary arm, a resilient arm connector, a top jaw, a lower jaw, and a deflector. The clamp is generally configured to receive a portion of the human or animal anatomy between the top jaw and the lower jaw when the clamp is in the second set position. In order to transition the clamp from the first unset position to the second set position a force is applied to the primary and secondary arms causing at least one of the top and lower jaws to contact and translate along the deflector until the top jaw and lower jaw are deflected. Next, the force is removed from the primary and secondary arms causing the resilient arm connector to bias the top and lower jaws toward one another.
摘要翻译： 公开了具有第一未设定位置和第二设定位置的挤压固定式医疗夹具。 夹具通常包括主臂，次臂，弹性臂连接器，顶颚，下颚和偏转器。 夹具通常构造成当夹具处于第二设定位置时接收顶部钳口和下钳口之间的人体或动物解剖结构的一部分。 为了将夹具从第一未设定位置转换到第二设定位置，将力施加到主臂和辅助臂，使得上下爪中的至少一个沿着偏转器接触和平移，直到顶颚和下颚 被偏转。 接下来，力从主臂和副臂移除，导致弹性臂连接器朝向彼此偏置上下爪。
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公开(公告)号：USD610685S1
公开(公告)日：2010-02-23
申请号：US29334740
申请日：2009-03-31
申请人： Peter A. Gaydos
设计人： Peter A. Gaydos
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公开(公告)号：US06820652B2
公开(公告)日：2004-11-23
申请号：US10328811
申请日：2002-12-24
IPC分类号： F16K1514
CPC分类号： F16K11/076 , F16K7/075 , Y10T137/7843 , Y10T137/7889 , Y10T137/7896 , Y10T137/87169 , Y10T137/87676
摘要： A multi-channel valve having a valve seat, a valve seal, and valve seal housing. The assembly of the apparatus creates a plurality of inlet, exit, and cross channels enclosed by elastomeric portions of a valve seal. The elastomeric portions of the valve seal create bounded distensible chambers. Pressure exerted by a fluid in excess of the cracking pressure of the seal tends to distend portions of the elastomeric seal and allow flow through and into the chambers. When inflow pressure falls, the elastic rebound of the elastomeric portions of the seal tends to expel fluid from the valve without backflow. Cross channel capacity allows mixing of the fluids. The plurality of, and differentials between, chambers allows one fluid to completely purge the valve of other fluids. The valve may be configured with additional backflow prevention capacities, such as channel variations, secondary elastomeric members, and variations in primary membrane properties.
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