公开(公告)号：US20050124892A1

公开(公告)日：2005-06-09

申请号：US10731302

申请日：2003-12-09

申请人： William Weitzel ,  Kang Kim ,  Matthew O'Donnell ,  Jonathan Rubin ,  Hua Xie ,  Xunchang Chen

发明人： William Weitzel ,  Kang Kim ,  Matthew O'Donnell ,  Jonathan Rubin ,  Hua Xie ,  Xunchang Chen

IPC分类号： A61B8/08 ,  A61B8/06

CPC分类号： A61B8/485 ,  A61B8/08

摘要： Methods and systems for measuring mechanical property of a vascular wall and a method and system for determining health of a vascular structure are provided wherein local deformation of a vessel wall resulting from physiologic pressures with altered transmural forces is measured. A non-invasive free-hand ultrasound scanning-procedure was performed to apply external force, comparable to the force generated in measuring a subject's blood pressure, to achieve higher strains by equalizing the internal arterial baseline pressure. When the applied pressure matched the internal baseline diastolic pressure, strain and strain rate increased by a factor of 10 over a cardiac cycle. Radial arterial strain was assessed in the vessel wall over the entire deformation procedure using a phase-sensitive, two-dimensional speckle-tracking algorithm. An elastic modulus reconstruction procedure was developed to estimate the non-linear elastic properties of the vascular wall.

摘要翻译： 提供了用于测量血管壁的机械性能的方法和系统以及用于确定血管结构健康的方法和系统，其中测量由具有改变的透壁力的生理压力引起的血管壁的局部变形。 进行非侵入性自由手超声扫描程序以施加外力，与测量受试者血压时产生的力相当，以通过平衡内部动脉基线压力来实现更高的应变。 当施加的压力与内部基线舒张压相匹配时，应变和应变率在心脏周期上增加10倍。 使用相敏二维斑点跟踪算法，在整个变形过程的血管壁中评估径向动脉应变。 开发弹性模量重建程序来估计血管壁的非线性弹性性质。

公开(公告)号：US07318804B2

公开(公告)日：2008-01-15

申请号：US10731302

申请日：2003-12-09

申请人： William F. Weitzel ,  Kang Kim ,  Matthew O'Donnell ,  Jonathan M. Rubin ,  Hua Xie ,  Xunchang Chen

发明人： William F. Weitzel ,  Kang Kim ,  Matthew O'Donnell ,  Jonathan M. Rubin ,  Hua Xie ,  Xunchang Chen

IPC分类号： A61B8/00

CPC分类号： A61B8/485 ,  A61B8/08

摘要： Methods and systems for measuring mechanical property of a vascular wall and a method and system for determining health of a vascular structure are provided wherein local deformation of a vessel wall resulting from physiologic pressures with altered transmural forces is measured. A non-invasive free-hand ultrasound scanning-procedure was performed to apply external force, comparable to the force generated in measuring a subject's blood pressure, to achieve higher strains by equalizing the internal arterial baseline pressure. When the applied pressure matched the internal baseline diastolic pressure, strain and strain rate increased by a factor of 10 over a cardiac cycle. Radial arterial strain was assessed in the vessel wall over the entire deformation procedure using a phase-sensitive, two-dimensional speckle-tracking algorithm. An elastic modulus reconstruction procedure was developed to estimate the non-linear elastic properties of the vascular wall.

摘要翻译： 提供了用于测量血管壁的机械性能的方法和系统以及用于确定血管结构健康的方法和系统，其中测量由具有改变的透壁力的生理压力引起的血管壁的局部变形。 进行非侵入性自由手超声扫描程序以施加外力，与测量受试者血压时产生的力相当，以通过平衡内部动脉基线压力来实现更高的应变。 当施加的压力与内部基线舒张压相匹配时，应变和应变率在心脏周期上增加10倍。 使用相敏二维斑点跟踪算法，在整个变形过程的血管壁中评估径向动脉应变。 开发弹性模量重建程序来估计血管壁的非线性弹性性质。

公开(公告)号：US20080081994A1

公开(公告)日：2008-04-03

申请号：US11866000

申请日：2007-10-02

申请人： KANG KIM ,  William Weitzel ,  Jonathan Rubin ,  Congxian Jia ,  Matthew O'Donnell ,  Theodore Kolias

发明人： KANG KIM ,  William Weitzel ,  Jonathan Rubin ,  Congxian Jia ,  Matthew O'Donnell ,  Theodore Kolias

IPC分类号： A61B8/00

CPC分类号： A61B5/0285 ,  A61B8/06 ,  A61B8/08 ,  A61B8/485 ,  G01S7/52036 ,  G01S7/52042

摘要： An optimized elastic modulus reconstruction procedure can estimate the nonlinear elastic properties of vascular wall from intramural strain and pulse wave velocity (PWV) measurements. A noninvasive free-hand ultrasound scanning procedure is used to apply external force, comparable to the force in measuring a subject's blood pressure, to achieve higher strains by equalizing the internal arterial baseline pressure. PWV is estimated at the same location where intramural strain is measured. The reconstructed elastic modulus is optimized and the arterial elastic modulus can be determined and monitored using a simple dual elastic modulus reconstruction procedure.

摘要翻译： 优化的弹性模量重建程序可以从壁内应变和脉搏波速度（PWV）测量中估计血管壁的非线性弹性特性。 使用非侵入性自由手超声扫描程序来施加外力，与测量受试者血压的力相当，以通过平衡内部动脉基线压力来实现更高的应变。 PWV估计在测量壁内应变的相同位置。 重建的弹性模量被优化，并且可以使用简单的双弹性模量重建程序来确定和监测动脉弹性模量。

公开(公告)号：US08167804B2

公开(公告)日：2012-05-01

申请号：US11866000

申请日：2007-10-02

申请人： Kang Kim ,  William F. Weitzel ,  Jonathan M. Rubin ,  Congxian Jia ,  Matthew O'Donnell ,  Theodore J. Kolias

发明人： Kang Kim ,  William F. Weitzel ,  Jonathan M. Rubin ,  Congxian Jia ,  Matthew O'Donnell ,  Theodore J. Kolias

IPC分类号： A61B8/00

CPC分类号： A61B5/0285 ,  A61B8/06 ,  A61B8/08 ,  A61B8/485 ,  G01S7/52036 ,  G01S7/52042

摘要： An optimized elastic modulus reconstruction procedure can estimate the nonlinear elastic properties of vascular wall from intramural strain and pulse wave velocity (PWV) measurements. A noninvasive free-hand ultrasound scanning procedure is used to apply external force, comparable to the force in measuring a subject's blood pressure, to achieve higher strains by equalizing the internal arterial baseline pressure. PWV is estimated at the same location where intramural strain is measured. The reconstructed elastic modulus is optimized and the arterial elastic modulus can be determined and monitored using a simple dual elastic modulus reconstruction procedure.

摘要翻译： 优化的弹性模量重建程序可以从壁内应变和脉搏波速度（PWV）测量中估计血管壁的非线性弹性特性。 使用非侵入性自由手超声扫描程序来施加外力，与测量受试者血压的力相当，以通过平衡内部动脉基线压力来实现更高的应变。 PWV估计在测量壁内应变的相同位置。 重建的弹性模量被优化，并且可以使用简单的双弹性模量重建程序来确定和监测动脉弹性模量。

公开(公告)号：US20080081995A1

公开(公告)日：2008-04-03

申请号：US11866023

申请日：2007-10-02

申请人： Kang Kim ,  Sheng-wen Huang ,  Russell Witte ,  Matthew O'Donnell

发明人： Kang Kim ,  Sheng-wen Huang ,  Russell Witte ,  Matthew O'Donnell

IPC分类号： A61B8/12

CPC分类号： A61B8/0858 ,  A61B8/587

摘要： Thermal strain imaging can be used to identify vascular plaques. Methods include heating and imaging with ultrasound to identify vulnerable plaques, which typically consist of a large lipid-rich core, in peripheral arteries of a patient. Lipid-bearing tissue has a negative temperature dependence of sound speed, whereas water-based tissue has a positive one, allowing thermal strain imaging to differentiate the two different types of tissues with high contrast to characterize plaque composition. Apparatus and methods of the present teachings allow noninvasive and reliable plaque identification.

摘要翻译： 热应变成像可用于鉴定血管斑块。 方法包括用超声波进行加热和成像，以鉴定在患者的外周动脉中通常由大的富脂质核心组成的易损斑块。 脂质组织具有声速的负温度依赖性，而水基组织具有阳性组织，允许热应变成像区分具有高对比度的两种不同类型的组织以表征斑块组成。 本发明的装置和方法允许非侵入性和可靠的斑块鉴定。

公开(公告)号：US20130008361A1

公开(公告)日：2013-01-10

申请号：US13365015

申请日：2012-02-02

申请人： Ramiro Trevino ,  Matthew O'Donnell ,  Brian O'Donnell

发明人： Ramiro Trevino ,  Matthew O'Donnell ,  Brian O'Donnell

IPC分类号： A01C23/02 ,  F17D3/00 ,  F16K37/00

CPC分类号： A01C23/007 ,  A01B79/005 ,  Y02P60/214 ,  Y10T137/8158 ,  Y10T137/85978

摘要： A system for fertilizing a large area. The system may include a fluid bar configured to be towed by a tractor. The fluid bar may include a fluid passageway with at least one aperture and a sensor or meter in communication with the aperture. The aperture may be configured to receive a hose or other attachment distributing fluid to the ground. The system may include a tank, a pump, pump controller and a filter. The pump flow rate and the outlet flow rate may be displayed on monitoring equipment located within a cab of the tractor. The pump controller may be used by the farmer to variably adjust the fluid pressure in each aperture and consequently adjust the flow pressure of fertilizer added to the ground.

摘要翻译： 一个大面积施肥系统。 该系统可以包括构造成由拖拉机牵引的流体杆。 流体条可以包括具有至少一个孔的流体通道和与孔连通的传感器或计量器。 孔可以被配置为接收将流体分配到地面的软管或其它附件。 该系统可以包括罐，泵，泵控制器和过滤器。 泵流量和出口流量可以显示在位于拖拉机驾驶室内的监控设备上。 泵控制器可以由农民使用以可变地调节每个孔中的流体压力，并且因此调节添加到地面的肥料的流动压力。

公开(公告)号：US20120118052A1

公开(公告)日：2012-05-17

申请号：US13273095

申请日：2011-10-13

申请人： Matthew O'Donnell ,  Xiaohu Gao

发明人： Matthew O'Donnell ,  Xiaohu Gao

IPC分类号： G01N29/02

CPC分类号： G01N29/2418 ,  G01N29/222 ,  G01N2291/02466

摘要： Method and system for background suppression in magneto-motive photoacoustic imaging of labeled target objects.

摘要翻译： 标记目标物体磁光成像中背景抑制的方法和系统。

公开(公告)号：US08094802B2

公开(公告)日：2012-01-10

申请号：US11831549

申请日：2007-07-31

申请人： Joaquin Omar Alvarado ,  David Bauer ,  Matthew O'Donnell

发明人： Joaquin Omar Alvarado ,  David Bauer ,  Matthew O'Donnell

IPC分类号： H04M3/00 ,  H04M5/00

CPC分类号： H04M3/523

摘要： A contact originator is given a choice to enqueue the contact in multiple contact queues, to serve multiple needs or interests of the originator. If the contact reaches the head of the queue for the primary need while the contact is being serviced from a queue for a secondary need, the contact either remains at the head of the primary-need queue until the servicing at the secondary-need queue is completed, or a resource of the primary-need queue is conferenced in with the contact and the resource of the secondary-need queue so that the resources can serve both needs simultaneously.

摘要翻译： 联系人发起者可以选择将联系人排队在多个联系人队列中，以满足发起者的多种需求或兴趣。 如果联系人在从辅助需求的队列中服务联系人的情况下到达主要需要的队列的头部，则该联系人将保留在主要需要队列的头部，直到辅助需要队列的服务为 或者主要需求队列的资源与辅助需求队列的联系人和资源进行会议，以便资源同时满足两个需求。

公开(公告)号：US07736317B2

公开(公告)日：2010-06-15

申请号：US10243823

申请日：2002-09-13

申请人： Douglas N. Stephens ,  Matthew O'Donnell

发明人： Douglas N. Stephens ,  Matthew O'Donnell

IPC分类号： A61B8/12

CPC分类号： B06B1/0633 ,  A61B8/12 ,  A61B8/445 ,  A61B8/4488 ,  Y10T29/42

摘要： An ultrasound transducer array (408) includes at least one transducer element (412) having a first (604) and second (606) portions separated by an acoustical discontinuity (520). The first portion (604) has the desired length to form a half-wave k31 resonance, while the second portion (606) has a resonant length for an undesired very low frequency out-of-band k31 resonance. The thickness of the transducer element (412) is designed for k33 half-resonance. Given the design, the transducer element (412) can operate and provide for both forward-looking (514) and side looking (512) elevation apertures. A method is also disclosed for using the disclosed ultrasound transducer (412) in ultrasound imaging.

摘要翻译： 超声换能器阵列（408）包括至少一个换能器元件（412），该换能器元件具有由声学不连续性（520）隔开的第一（604）和第二（606）部分。 第一部分（604）具有期望的长度以形成半波k31谐振，而第二部分（606）具有用于不期望的非常低频带外k31谐振的谐振长度。 换能器元件（412）的厚度被设计用于k33半共振。 考虑到设计，换能器元件（412）可以操作并提供前视（514）和侧视（512）仰角孔。 还公开了在超声成像中使用所公开的超声换能器（412）的方法。

公开(公告)号：US06852082B2

公开(公告)日：2005-02-08

申请号：US10198429

申请日：2002-07-17

申请人： Adam Strickberger ,  Charles Cain ,  Matthew O'Donnell

发明人： Adam Strickberger ,  Charles Cain ,  Matthew O'Donnell

IPC分类号： A61F6/20 ,  A61B8/14

CPC分类号： A61F6/20

摘要： Apparatuses and methods for performing non-invasive vasectomies are provided. In a preferred embodiment, an apparatus according to the present invention comprises a main body defining a recess and an ultrasonic transducer disposed adjacent said recess and adapted to emit ultrasonic energy into said recess. A tissue clamp is removeably disposed in the recess and is adapted to receive parallel sections of a scrotum that include a portion of the vas deferens. The clamp is further adapted to position the vas deferens within an effective distance of the ultrasonic transducer. Also, the apparatus includes means for retaining the parallel sections and the vas deferens within the clamp during a procedure.

摘要翻译： 提供了用于执行非侵入性输精管切除术的装置和方法。 在优选实施例中，根据本发明的装置包括限定凹部的主体和邻近所述凹部设置并适于向所述凹部发射超声波能量的超声波换能器。 组织夹具可移除地设置在凹部中并且适于接收包括输精管的一部分的阴囊的平行部分。 夹具还适于将输精管定位在超声换能器的有效距离内。 此外，该装置还包括用于在手术期间将夹持器中的平行部分和输精管保持在夹具内的装置。