摘要:
The present invention is directed to isolated amyloid precursor-like proteins (APLPs), nucleotide sequences coding for and regulating expression of these protein, antibodies directed against these proteins, and recombinant vectors and host cells containing the genetic sequences coding for and regulating the expression of these protein sequences. The invention is also directed to isolated genomic. DNA, cDNA anti-sense RNA, and RNA containing the protein sequence. Antibodies can be used to detect an APLP in biological specimens, including, for example, fluid, serum or tissue samples. APLP1 and APLP2 are candidate genes for late onset familial Alzheimer's disease.
摘要:
The present invention is directed to isolated amyloid precursor-like proteins (APLPs), nucleotide sequences coding for and regulating expression of these protein, antibodies directed against these proteins, and recombinant vectors and host cells containing the genetic sequences coding for and regulating the expression of these protein sequences. The invention is also directed to isolated genomic DNA, cDNA anti-sense RNA, and RNA containing the protein sequence. Antibodies can be used to detect an APLP in biological specimens, including, for example, fluid, serum or tissue samples. APLP1 and APLP2 are candidate genes for late onset familial Alzheimer's disease.
摘要:
Disclosed are gas fed, porous electrodes capable of steady, high current density operation for practical periods of service, e.g. as oxygen cathodes in metal-air batteries. The subject electrodes feature at least two bonded composite layers, one of which is a form-stable, conductive wetproofing layer while the other is an unusually thin active layer containing active carbon particles predominantly between about 2 and about 20 micrometers and having a high internal surface area, e.g. a B.E.T. surface area of over 1000 m.sup.2 /gram. A simple and highly successful method of preparing such electrodes is also disclosed, which avoids the necessity of separately forming and handling the thin active layer.
摘要:
This disclosure is directed to a process for extracting PTFE-wetting agent from PTFE particles containing small amounts of wetting agent in admixture with carbon particles comprising contacting said mixture with an organic liquid medium capable of extracting said wetting agent, and electrodes containing such extracted mixes. Also disclosed is a process for forming an electrode layer by depositing a soluble salt on a filter medium, depositing electrode layer material on said salt consolidating said electrode material and thereafter dissolving said salt.
摘要:
This disclosure is directed to preparing deashed, precious metal catalyst-containing, partially fluorinated active carbon particles of the formula CF.sub.x, where x ranges from 0.1 to about 0.18, preferably using either platinum or silver as the catalyzing material, which can be incorporated into an active layer component of a gas electrode, e.g., an oxygen (air) cathode suitable for use in a chlor-alkali electrolytic cell for producing chlorine and caustic while conserving electrical energy. These particles are deashed to have a B.E.T. surface area of at least 600 m.sup.2 /g and contain less than about 4 weight percent ash. Active electrode layers containing such particles demonstrate an unusually desirable combination of resistance to corrosion, retention of conductive properties and retention of catalytic surface area.
摘要:
A battery assembly of the consumable metal anode type has now been constructed for ready assembly as well as disassembly. In a non-conductive and at least substantially inert cell body, space is provided for receiving an open-structured, non-consumable anode cage. The cage has an open top for facilitating insertion of an anode. A modular cathode is used, comprising a peripheral current conductor frame clamped about a grid reinforced air cathode in sheet form. The air cathode may be double gridded. The cathode frame can be sealed, during assembly, with electrolyte-resistant-sealant as well as with adhesive. The resulting cathode module can be assembled outside the cell body and readily inserted therein, or can later be easily removed therefrom.
摘要:
A unitized electrode-intercell connector module is prepared for use in a bipolar electrode, especially for use in such electrode of the M-alkaline electrolyte-AgO types. In such special electrode, an imperforate foil, contacted with a conductive foam, is plated to a unitized, electrobonded assembly. Pyrolysis can lighten the assembly and may further provide for subsequent resistance to attack in an electrode environment. For the special electrode the reticulate portion of the assembly can be filled to provide an AgO electrode and the bipolar electrode completed by using a suitable electronegative metal on the foil side opposite from the AgO electrode.
摘要:
The active layer of an electrode is laminated on its working surface to a current distributor and on its opposite surface to a porous coherent, hydrophobic, wetproofing layer. The active layer contains from about 60 to about 85 wt. % active carbon particles bound in a matrix of a fibrillated mixture of a fluorocarbon polymer and carbon black. The electrode is useful in chlor-alkali cells.
摘要:
This disclosure is directed to the preparation of cohesive, self-sustaining electrode backing layers by a method comprising mixing from about 20 to about 50 weight parts of polytetrafluoroethylene (PTFE) having a particle size ranging from 0.05 to 0.5 micron with from about 50 to about 80 weight parts of a partially fluorinated carbon black of the formula CF.sub.x, where x is from about 0.1 to about 0.18 and having particles of a size ranging from about 50 to about 3000 angstroms to produce an electrode backing layer having a combination of enhanced electrical conductivity and hydrophobicity.
摘要:
This disclosure is directed to a gas diffusion electrode, e.g., an oxygen (air) electrode, having a conductive, porous, sintered, plaque metal substrate containing generally spherically-shaped anchor site depressions on its active layer-contacting surface; an active layer containing catalyzed or uncatalyzed carbon particles and whose plaque-contacting surface includes anchor portions which interlock with the anchor site depressions and assist in securing the active layer to the plaque substrate, and a hydrophobic backing (wetproofing) layer in contact with the other surface of the active layer. The plaque is made by forming, e.g., by rolling or pressing, the metal powder, preferably silver, containing particulate extractable material on one face or surface thereof into a thin plaque; sintering the plaque containing the extractable material at temperatures of from about 1000.degree. to about 1300.degree. F. for time periods of from about 2 to about 30 minutes and thereafter removing the extractable material to produce a plaque electrode substrate having anchor site depressions in one surface. The active layer material is then deposited, preferably by filtration, on the plaque surface having such depressions followed by depositing the hydrophobic layer, also preferably by filtration.