-
公开(公告)号：US20070208019A1
公开(公告)日：2007-09-06
申请号：US11653190
申请日：2007-01-11
申请人： Wolfgang Wrasidlo , John Doukas , Ivor Royston , Glenn Noronha , John Hood , Elena Dneprovskaia , Xianchang Gong , Ute Splittgerber , Ningning Zhao
发明人： Wolfgang Wrasidlo , John Doukas , Ivor Royston , Glenn Noronha , John Hood , Elena Dneprovskaia , Xianchang Gong , Ute Splittgerber , Ningning Zhao
IPC分类号： A61K31/5377 , A61K31/525 , A61K39/395 , A61K31/704 , A61K31/7048 , A61K31/337 , A61K31/404
CPC分类号： C07D209/14 , C07D209/48 , C07D239/88 , C07D239/90 , C07D239/95 , C07D241/42 , C07D253/10 , C07D401/12 , C07D403/12 , C07D405/04 , C07D405/12 , C07D471/04 , C07D487/04
摘要： Compositions and methods and are provided for treating disorders associated with compromised vasculostasis. Invention methods and compositions are useful for treating a variety of disorders including for example, stroke, myocardial infarction, cancer, ischemia/reperfusion injury, autoimmune diseases such as rheumatoid arthritis, eye diseases such as retinopathies or macular degeneration or other vitreoretinal diseases, inflammatory diseases, vascular leakage syndrome, edema, transplant rejection, adult/acute respiratory distress syndrome (ARDS), and the like.
摘要翻译： 组合物和方法，用于治疗与受损的血管淤滞相关的疾病。 本发明的方法和组合物可用于治疗各种疾病，包括例如中风，心肌梗塞，癌症，缺血/再灌注损伤，自身免疫性疾病如类风湿性关节炎，眼睛疾病如视网膜病变或黄斑变性或其他玻璃体视网膜疾病，炎性疾病 ，血管渗漏综合征，水肿，移植排斥，成人/急性呼吸窘迫综合征（ARDS）等。
-
公开(公告)号：US20050282814A1
公开(公告)日：2005-12-22
申请号：US11105845
申请日：2005-04-13
申请人： Wolfgang Wrasidlo , John Doukas , Ivor Royston , Glenn Noronha , John Hood , Elena Dneprovskaia , Xianchang Gong , Ute Splittgerber , Ningning Zhao
发明人： Wolfgang Wrasidlo , John Doukas , Ivor Royston , Glenn Noronha , John Hood , Elena Dneprovskaia , Xianchang Gong , Ute Splittgerber , Ningning Zhao
IPC分类号： C07D209/14 , A61K31/405 , A61K31/525 , A61K31/724 , C07D209/02 , C07D209/04 , C07D209/48 , C07D239/88 , C07D239/90 , C07D239/95 , C07D241/42 , C07D253/10 , C07D401/12 , C07D403/12 , C07D405/04 , C07D405/12 , C07D471/04 , C07D487/04 , C07D519/00
CPC分类号： C07D209/14 , A61K31/337 , A61K31/519 , A61K31/704 , A61K31/724 , A61K45/06 , C07D209/48 , C07D239/88 , C07D239/90 , C07D239/95 , C07D241/42 , C07D253/10 , C07D401/12 , C07D403/12 , C07D405/04 , C07D405/12 , C07D471/04 , C07D487/04 , A61K2300/00
摘要： Compositions and methods and are provided for treating disorders associated with compromised vasculostasis. Invention methods and compositions are useful for treating a variety of disorders including for example, stroke, myocardial infarction, cancer, ischemia/reperfusion injury, autoimmune diseases such as rheumatoid arthritis, eye diseases such as retinopathies or macular degeneration or other vitreoretinal diseases, inflammatory diseases, vascular leakage syndrome, edema, transplant rejection, adult/acute respiratory distress syndrome (ARDS), and the like.
摘要翻译： 组合物和方法，用于治疗与受损的血管淤滞相关的疾病。 本发明的方法和组合物可用于治疗各种疾病，包括例如中风，心肌梗塞，癌症，缺血/再灌注损伤，自身免疫性疾病如类风湿性关节炎，眼睛疾病如视网膜病变或黄斑变性或其他玻璃体视网膜疾病，炎性疾病 ，血管渗漏综合征，水肿，移植排斥，成人/急性呼吸窘迫综合征（ARDS）等。
-
公开(公告)号：US07208493B2
公开(公告)日：2007-04-24
申请号：US10679209
申请日：2003-10-02
申请人： Wolfgang Wrasidlo , John Doukas , Ivor Royston , Glenn Noronha , John D. Hood , Elena Dneprovskaia , Xianchang Gong , Ute Splittgerber , Ningning Zhao
发明人： Wolfgang Wrasidlo , John Doukas , Ivor Royston , Glenn Noronha , John D. Hood , Elena Dneprovskaia , Xianchang Gong , Ute Splittgerber , Ningning Zhao
IPC分类号： A61K31/4985 , C07D471/02
CPC分类号： C07D209/14 , C07D209/48 , C07D239/88 , C07D239/90 , C07D239/95 , C07D241/42 , C07D253/10 , C07D401/12 , C07D403/12 , C07D405/04 , C07D405/12 , C07D471/04 , C07D487/04
摘要： Compositions and methods and are provided for treating disorders associated with compromised vasculostasis. Invention methods and compositions are useful for treating a variety of disorders including for example, stroke, myocardial infarction, cancer, ischemia/reperfusion injury, autoimmune diseases such as rheumatoid arthritis, eye diseases such as retinopathies or macular degeneration or other vitreoretinal diseases , inflammatory diseases, vascular leakage syndrome, edema, transplant rejection, adult/acute respiratory distress syndrome (ARDS), and the like.
摘要翻译： 组合物和方法，用于治疗与受损的血管淤滞相关的疾病。 本发明的方法和组合物可用于治疗各种疾病，包括例如中风，心肌梗塞，癌症，缺血/再灌注损伤，自身免疫性疾病如类风湿性关节炎，眼睛疾病如视网膜病变或黄斑变性或其他玻璃体视网膜疾病，炎性疾病 ，血管渗漏综合征，水肿，移植排斥，成人/急性呼吸窘迫综合征（ARDS）等。
-
公开(公告)号：US20100330030A1
公开(公告)日：2010-12-30
申请号：US12780401
申请日：2010-05-14
申请人： Wolfgang Wrasidlo , John Doukas , Ivor Royston , Glenn Noronha , John D. Hood , Elena Dneprovskaia , Xianchang Gong , Ute Splittgerber , Ningning Zhao
发明人： Wolfgang Wrasidlo , John Doukas , Ivor Royston , Glenn Noronha , John D. Hood , Elena Dneprovskaia , Xianchang Gong , Ute Splittgerber , Ningning Zhao
IPC分类号： A61K39/395 , A61K31/498 , A61K31/4985 , A61K33/24 , A61K38/12 , A61K31/7048 , A61K31/704 , A61K38/20 , A61P35/00 , A61P35/02
CPC分类号： C07D209/14 , A61K31/337 , A61K31/519 , A61K31/704 , A61K31/724 , A61K45/06 , C07D209/48 , C07D239/88 , C07D239/90 , C07D239/95 , C07D241/42 , C07D253/10 , C07D401/12 , C07D403/12 , C07D405/04 , C07D405/12 , C07D471/04 , C07D487/04 , A61K2300/00
摘要： Compositions and methods and are provided for treating disorders associated with compromised vasculostasis. Invention methods and compositions are useful for treating a variety of disorders including for example, stroke, myocardial infarction, cancer, ischemia/reperfusion injury, autoimmune diseases such as rheumatoid arthritis, eye diseases such as retinopathies or macular degeneration or other vitreoretinal diseases, inflammatory diseases, vascular leakage syndrome, edema, transplant rejection, adult/acute respiratory distress syndrome (ARDS), and the like.
摘要翻译： 组合物和方法，用于治疗与受损的血管淤滞相关的疾病。 本发明的方法和组合物可用于治疗各种疾病，包括例如中风，心肌梗塞，癌症，缺血/再灌注损伤，自身免疫性疾病如类风湿性关节炎，眼睛疾病如视网膜病变或黄斑变性或其他玻璃体视网膜疾病，炎性疾病 ，血管渗漏综合征，水肿，移植排斥，成人/急性呼吸窘迫综合征（ARDS）等。
-
公开(公告)号：US20100278811A1
公开(公告)日：2010-11-04
申请号：US12628306
申请日：2009-12-01
申请人： Wolfgang Wrasidlo , John Doukas , Ivor Royston , Glenn Noronha , John D. Hood , Elena Dneprovskaia , Xianchang Gong , Ute Splittgerber , Ningning Zhao
发明人： Wolfgang Wrasidlo , John Doukas , Ivor Royston , Glenn Noronha , John D. Hood , Elena Dneprovskaia , Xianchang Gong , Ute Splittgerber , Ningning Zhao
IPC分类号： A61K39/395 , A61K31/404 , A61K31/5377 , A61K31/519 , A61K31/53 , A61K31/517 , A61K31/407 , A61K38/14 , A61K33/24 , A61K31/704 , A61P35/00 , A61P11/06 , A61P27/02 , A61P9/00
CPC分类号： C07D209/14 , C07D209/48 , C07D239/88 , C07D239/90 , C07D239/95 , C07D241/42 , C07D253/10 , C07D401/12 , C07D403/12 , C07D405/04 , C07D405/12 , C07D471/04 , C07D487/04
摘要： Compositions and methods and are provided for treating disorders associated with compromised vasculostasis. Invention methods and compositions are useful for treating a variety of disorders including for example, stroke, myocardial infarction, cancer, ischemia/reperfusion injury, autoimmune diseases such as rheumatoid arthritis, eye diseases such as retinopathies or macular degeneration or other vitreoretinal diseases, inflammatory diseases, vascular leakage syndrome, edema, transplant rejection, adult/acute respiratory distress syndrome (ARDS), and the like.
摘要翻译： 组合物和方法，用于治疗与受损的血管淤滞相关的疾病。 本发明的方法和组合物可用于治疗各种疾病，包括例如中风，心肌梗塞，癌症，缺血/再灌注损伤，自身免疫性疾病如类风湿性关节炎，眼睛疾病如视网膜病变或黄斑变性或其他玻璃体视网膜疾病，炎性疾病 ，血管渗漏综合征，水肿，移植排斥，成人/急性呼吸窘迫综合征（ARDS）等。
-
公开(公告)号：US20090275569A1
公开(公告)日：2009-11-05
申请号：US12207019
申请日：2008-09-09
申请人： Xianchang Gong , Kathy Barrett , Jianguo Cao , Colleen Gritzen , Glenn Noronha , John D. Hood , Chi Ching Mak , Andrew McPherson , Ved Prakash Pathak , Joel Renick , Richard M. Soll , Ute Splittgerber , Wolfgang Wrasidlo , Ningning Zhao , Elena Dneprovskaia , Binqi Zeng , Glenn Noronha
发明人： Xianchang Gong , Kathy Barrett , Jianguo Cao , Colleen Gritzen , Glenn Noronha , John D. Hood , Chi Ching Mak , Andrew McPherson , Ved Prakash Pathak , Joel Renick , Richard M. Soll , Ute Splittgerber , Wolfgang Wrasidlo , Ningning Zhao , Elena Dneprovskaia , Binqi Zeng , Glenn Noronha
IPC分类号： A61K31/5377 , C07D403/12 , A61K31/541 , A61K31/53 , C07D417/12 , C07D413/12
CPC分类号： C07D253/08 , C07D403/04 , C07D403/12 , C07D413/04
摘要： The invention provides benzotriazine compounds having formula (I). The benzotriazine compounds of the invention are capable of inhibiting kinases, such members of the Src kinase family, and various other specific receptor and non-receptor kinases.
摘要翻译： 本发明提供具有式（I）的苯并三嗪化合物。 本发明的苯并三嗪化合物能够抑制激酶，Src激酶家族的成员和各种其它特异性受体和非受体激酶。
-
公开(公告)号：US08481536B2
公开(公告)日：2013-07-09
申请号：US12980235
申请日：2010-12-28
申请人： Xianchang Gong , Kathy Barrett , Jianguo Cao , Colleen Gritzen , Glenn Noronha , John D. Hood , Chi Ching Mak , Andrew McPherson , Ved Prakash Pathak , Joel Renick , Richard M. Soll , Ute Splittgerber , Wolfgang Wrasidlo , Binqi Zeng , Ningning Zhao , Elena Dneprovskaia
发明人： Xianchang Gong , Kathy Barrett , Jianguo Cao , Colleen Gritzen , Glenn Noronha , John D. Hood , Chi Ching Mak , Andrew McPherson , Ved Prakash Pathak , Joel Renick , Richard M. Soll , Ute Splittgerber , Wolfgang Wrasidlo , Binqi Zeng , Ningning Zhao , Elena Dneprovskaia
IPC分类号： A61K31/53 , A61P35/00 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/12 , C07D403/14 , C07D413/12 , C07D413/14 , C07D417/12 , C07D417/14
CPC分类号： C07D253/08 , C07D403/04 , C07D403/12 , C07D413/04
摘要： The invention provides benzotriazine compounds having formula (I). The benzotriazine compounds of the invention are capable of inhibiting kinases, such members of the Src kinase family, and various other specific receptor and non-receptor kinases.
摘要翻译： 本发明提供具有式（I）的苯并三嗪化合物。 本发明的苯并三嗪化合物能够抑制激酶，Src激酶家族的成员和各种其它特异性受体和非受体激酶。
-
公开(公告)号：US20110294796A1
公开(公告)日：2011-12-01
申请号：US12980235
申请日：2010-12-28
申请人： Xianchang Gong , Kathy Barrett , Jianguo Cao , Colleen Gritzen , John D. Hood , Chi Ching Mak , Andrew McPherson , Ved Prakash Pathak , Joel Renick , Richard M. Soll , Ute Splittgerber , Wolfgang Wrasidlo , Ningning Zhao , Elena Dneprovskaia , Binqi Zeng , Glenn Noronha
发明人： Xianchang Gong , Kathy Barrett , Jianguo Cao , Colleen Gritzen , John D. Hood , Chi Ching Mak , Andrew McPherson , Ved Prakash Pathak , Joel Renick , Richard M. Soll , Ute Splittgerber , Wolfgang Wrasidlo , Ningning Zhao , Elena Dneprovskaia , Binqi Zeng , Glenn Noronha
IPC分类号： A61K31/53 , C07D253/10 , C07D401/12 , C07D413/12 , C07D417/12 , A61K31/5377 , A61K31/541 , A61P9/10 , A61P35/00 , A61P11/00 , A61P17/02 , A61P19/02 , A61P7/00 , A61P9/00 , A61P37/00 , A61P29/00 , C07D403/12
CPC分类号： C07D253/08 , C07D403/04 , C07D403/12 , C07D413/04
摘要： The invention provides benzotriazine compounds having formula (I). The benzotriazine compounds of the invention are capable of inhibiting kinases, such members of the Src kinase family, and various other specific receptor and non-receptor kinases.
摘要翻译： 本发明提供具有式（I）的苯并三嗪化合物。 本发明的苯并三嗪化合物能够抑制激酶，Src激酶家族的成员和各种其它特异性受体和非受体激酶。
-
公开(公告)号：US07456176B2
公开(公告)日：2008-11-25
申请号：US11102405
申请日：2005-04-07
申请人： Glenn Noronha , Kathy Barrett , Jianguo Cao , Colleen Gritzen , Xianchang Gong , John D. Hood , Chi Ching Mak , Andrew McPherson , Ved Prakash Pathak , Joel Renick , Richard M. Soll , Ute Splittgerber , Wolfgang Wrasidlo , Binqi Zeng , Ningning Zhao , Elena Dneprovskaia
发明人： Glenn Noronha , Kathy Barrett , Jianguo Cao , Colleen Gritzen , Xianchang Gong , John D. Hood , Chi Ching Mak , Andrew McPherson , Ved Prakash Pathak , Joel Renick , Richard M. Soll , Ute Splittgerber , Wolfgang Wrasidlo , Binqi Zeng , Ningning Zhao , Elena Dneprovskaia
IPC分类号： C07D401/12 , C07D401/14 , C07D403/04 , C07D403/12 , C07D403/14 , C07D413/12 , C07D413/14 , C07D417/12 , C07D417/14 , A61K31/53 , A61P19/02 , A61P35/00
CPC分类号： C07D253/08 , C07D403/04 , C07D403/12 , C07D413/04
摘要： The invention provides benzotriazine compounds having formula (I). The benzotriazine compounds of the invention are capable of inhibiting kinases, such members of the Src kinase family, and various other specific receptor and non-receptor kinases.
摘要翻译： 本发明提供具有式（I）的苯并三嗪化合物。 本发明的苯并三嗪化合物能够抑制激酶，Src激酶家族的成员和各种其它特异性受体和非受体激酶。
-
公开(公告)号：US20050245524A1
公开(公告)日：2005-11-03
申请号：US11102405
申请日：2005-04-07
申请人： Glenn Noronha , Kathy Barrett , Jianguo Cao , Colleen Gritzen , Xianchang Gong , John Hood , Chi Mak , Andrew McPherson , Ved Pathak , Joel Renick , Richard Soll , Ute Splittgerber , Wolfgang Wrasdilo , Ningning Zhao , Elena Dneprovskaia
发明人： Glenn Noronha , Kathy Barrett , Jianguo Cao , Colleen Gritzen , Xianchang Gong , John Hood , Chi Mak , Andrew McPherson , Ved Pathak , Joel Renick , Richard Soll , Ute Splittgerber , Wolfgang Wrasdilo , Ningning Zhao , Elena Dneprovskaia
CPC分类号： C07D253/08 , C07D403/04 , C07D403/12 , C07D413/04
摘要： The invention provides benzotriazine compounds having formula (I). The benzotriazine compounds of the invention are capable of inhibiting kinases, such members of the Src kinase family, and various other specific receptor and non-receptor kinases.
摘要翻译： 本发明提供具有式（I）的苯并三嗪化合物。 本发明的苯并三嗪化合物能够抑制激酶，Src激酶家族的成员和各种其它特异性受体和非受体激酶。
-
-
-
-
-
-
-
-
-
搜索结果
10 条记录 (耗时 0.06 秒)
