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    Method and apparatus for predicting recurring ventricular arrhythmias
    3.
    发明授权
    Method and apparatus for predicting recurring ventricular arrhythmias 有权
    用于预测复发性室性心律失常的方法和装置

    公开(公告)号：US06922585B2

    公开(公告)日：2005-07-26

    申请号：US10117465

    申请日：2002-04-05

    申请人： Xiaohong Zhou ,  Vinod Sharma ,  Walter H. Olson

    发明人： Xiaohong Zhou ,  Vinod Sharma ,  Walter H. Olson

    IPC分类号： A61B5/0452 ,  A61B5/0402 ,  A61B5/046 ,  A61B5/0464 ,  A61N1/362 ,  A61N1/37 ,  A61N1/39

    CPC分类号： A61B5/4035 ,  A61B5/046 ,  A61B5/0464 ,  A61N1/3622 ,  A61N1/3962

    摘要： An implantable medical device and method are provided for assessing autonomic tone and risk factors associated with arrhythmias and, based on this assessment, an early recurrence of ventricular tachycardia or ventricular fibrillation is predicted. Specifically, changes in R—R interval, heart rate variability, patient activity, and myocardial ischemia are measured prior to and after a detected an arrhythmia episode. A recurrence score is calculated as a weighted sum of measured parameters and compared to a prediction criterion. The prediction criterion may be a preset threshold score or an individualized episode template based on previously calculated recurrence scores associated with recurring episodes. Stored parameters and episode-related data may be downloaded for offline analyses for optimizing prediction criteria and monitoring patient status.

    摘要翻译： 提供了一种用于评估与心律失常相关的自主神经和风险因素的可植入医疗装置和方法，并且基于该评估，预测了室性心动过速或心室颤动的早期复发。 具体地，在检测到心律失常发作之前和之后测量R-R间期，心率变异性，患者活动和心肌缺血的变化。 计算复发得分作为测量参数的加权和并与预测标准进行比较。 预测标准可以是基于先前计算的与重复发作相关联的复发评分的预设阈值评分或个体化发作模板。 可以下载存储的参数和与剧集相关的数据用于离线分析，以优化预测标准和监测患者状态。

    Shunt-current reduction techniques for an implantable therapy system
    6.
    发明授权
    Shunt-current reduction techniques for an implantable therapy system 有权
    用于植入式治疗系统的分流电流还原技术

    公开(公告)号：US09192769B2

    公开(公告)日：2015-11-24

    申请号：US12551331

    申请日：2009-08-31

    申请人： William T. Donofrio ,  John E. Burnes ,  Paul G. Krause ,  Gerald P. Arne ,  Xiaohong Zhou

    发明人： William T. Donofrio ,  John E. Burnes ,  Paul G. Krause ,  Gerald P. Arne ,  Xiaohong Zhou

    IPC分类号： A61N1/08 ,  A61N1/37 ,  A61N1/36 ,  A61N1/372

    CPC分类号： A61N1/3718 ,  A61N1/08 ,  A61N1/086 ,  A61N1/36114 ,  A61N1/37288

    摘要： Techniques for minimizing interference between the first and second medical devices or between the different therapy modules of a common medical device are described herein. In some examples, a medical device may include shunt-current mitigation circuitry and/or at least one clamping structure that helps minimize or even eliminate shunt-current that feeds into a first therapy module of the medical device via one or more electrodes electrically connected to the first therapy module. The shunt-current may be generated by the delivery of electrical stimulation by a second therapy module. The second therapy module may be enclosed in a common housing with the first therapy module or may be separate, e.g., a part of a separate medical device.

    摘要翻译： 本文描述了用于最小化第一和第二医疗装置之间或在普通医疗装置的不同治疗模块之间的干扰的技术。 在一些示例中，医疗装置可以包括分流电流缓解电路和/或至少一个夹持结构，其有助于最小化或甚至消除通过电连接到医疗装置的一个或多个电极馈入医疗装置的第一治疗模块的分流电流 第一疗法模块。 分流电流可以通过第二治疗模块的电刺激递送来产生。 第二治疗模块可以用第一治疗模块封闭在共同的壳体中，或者可以是分离的，例如单独的医疗装置的一部分。

    METHOD AND APPARATUS FOR MONITORING CARDIAC AND RESPIRATORY CONDITIONS USING ACOUSTIC SOUNDS
    8.
    发明申请
    METHOD AND APPARATUS FOR MONITORING CARDIAC AND RESPIRATORY CONDITIONS USING ACOUSTIC SOUNDS 审中-公开
    使用声音监测心脏和呼吸系统状况的方法和装置

    公开(公告)号：US20130060150A1

    公开(公告)日：2013-03-07

    申请号：US13456357

    申请日：2012-04-26

    申请人： Zhendong Song ,  Xiaohong Zhou

    发明人： Zhendong Song ,  Xiaohong Zhou

    IPC分类号： A61B5/0205 ,  A61B7/00 ,  A61B5/08

    CPC分类号： A61B7/003 ,  A61B5/02 ,  A61B5/0205 ,  A61B5/0826 ,  A61B7/00 ,  A61N1/3627 ,  A61N1/36514

    摘要： A medical device system and associated method discriminating conditions that includes a plurality of sensors, a sensing module coupled to the plurality of sensors and configured to acquire signals from the plurality of sensors, and a processor coupled to the sensing module and configured to determine a change in a respiratory related sounds in response to a signal from a sensor of the plurality of sensors, select one or more sensors of the plurality of sensors associated with the determined change, determine a respiratory signature in response to signals from the selected one or more sensors, and determine the respiratory condition in response to the determined respiratory signature.

    摘要翻译： 一种医疗设备系统和相关联的方法来区分包括多个传感器的条件，耦合到多个传感器并被配置为从多个传感器获取信号的感测模块以及耦合到感测模块并被配置为确定变化的处理器 在响应于来自多个传感器的传感器的信号的呼吸相关声音中，选择与所确定的变化相关联的多个传感器中的一个或多个传感器，响应于来自所选择的一个或多个传感器的信号来确定呼吸特征 并且响应于所确定的呼吸标志来确定呼吸状况。

    METHOD AND APPARATUS FOR MONITORING CARDIAC AND RESPIRATORY CONDITIONS USING ACOUSTIC SOUNDS
    9.
    发明申请
    METHOD AND APPARATUS FOR MONITORING CARDIAC AND RESPIRATORY CONDITIONS USING ACOUSTIC SOUNDS 审中-公开
    使用声音监测心脏和呼吸道条件的方法和装置

    公开(公告)号：US20130060149A1

    公开(公告)日：2013-03-07

    申请号：US13456346

    申请日：2012-04-26

    申请人： Zhendong Song ,  Xiaohong Zhou

    发明人： Zhendong Song ,  Xiaohong Zhou

    IPC分类号： A61B7/00 ,  A61B5/0205

    摘要： A medical device system and associated method discriminate respiratory and cardiac conditions using respiratory sounds. A sensing module acquires a first signal and a second signal, at least the second signal acquired from an acoustic transducer. A processor is configured to receive the first signal and to control the sensing module to acquire the second acoustic signal in response to a change in the first signal. The processor discriminates between a cardiac condition and a respiratory condition as a cause of the change in the first signal in response to the second acoustic signal.

    摘要翻译： 医疗设备系统和相关方法使用呼吸音来辨别呼吸和心脏病状。 感测模块​​至少从声换能器获取的第二信号获取第一信号和第二信号。 处理器被配置为接收第一信号并且响应于第一信号的改变来控制感测模块获取第二声信号。 处理器根据第二声信号，将心脏状况与呼吸状况鉴别为第一信号的变化的原因。